In this paper we investigate optimal control problems governed by a advection-diffusion-reaction equation. We present a method for deriving conditions in the form of Pontryagin’s principle. The main tools used are th...In this paper we investigate optimal control problems governed by a advection-diffusion-reaction equation. We present a method for deriving conditions in the form of Pontryagin’s principle. The main tools used are the Ekeland’s variational principle combined with penalization and spike variation techniques.展开更多
By using the properties of w-distances and Gerstewitz's functions, we first give a vectorial Takahashi's nonconvex minimization theorem with a w-distance. From this, we deduce a general vectorial Ekeland's variatio...By using the properties of w-distances and Gerstewitz's functions, we first give a vectorial Takahashi's nonconvex minimization theorem with a w-distance. From this, we deduce a general vectorial Ekeland's variational principle, where the objective function is from a complete metric space into a pre-ordered topological vector space and the perturbation contains a w-distance and a non-decreasing function of the objective function value. From the general vectorial variational principle, we deduce a vectorial Caristfs fixed point theorem with a w-distance. Finally we show that the above three theorems are equivalent to each other. The related known results are generalized and improved. In particular, some conditions in the theorems of [Y. Araya, Ekeland's variational principle and its equivalent theorems in vector optimization, J. Math. Anal. Appl. 346(2008), 9-16] are weakened or even completely relieved.展开更多
Fuel consumption is one of the main concerns for heavy-duty trucks.Predictive cruise control(PCC)provides an intriguing opportunity to reduce fuel consumption by using the upcoming road information.In this study,a rea...Fuel consumption is one of the main concerns for heavy-duty trucks.Predictive cruise control(PCC)provides an intriguing opportunity to reduce fuel consumption by using the upcoming road information.In this study,a real-time implementable PCC,which simultaneously optimizes engine torque and gear shifting,is proposed for heavy-duty trucks.To minimize fuel consumption,the problem of the PCC is formulated as a nonlinear model predictive control(MPC),in which the upcoming road elevation information is used.Finding the solution of the nonlinear MPC is time consuming;thus,a real-time implementable solver is developed based on Pontryagin’s maximum principle and indirect shooting method.Dynamic programming(DP)algorithm,as a global optimization algorithm,is used as a performance benchmark for the proposed solver.Simulation,hardware-in-the-loop and real-truck experiments are conducted to verify the performance of the proposed controller.The results demonstrate that the MPC-based solution performs nearly as well as the DP-based solution,with less than 1%deviation for testing roads.Moreover,the proposed co-optimization controller is implementable in a real-truck,and the proposed MPC-based PCC algorithm achieves a fuel-saving rate of 7.9%without compromising the truck’s travel time.展开更多
The utilization of traffic information received from intelligent vehicle highway systems(IVHS) to plan velocity and split output power for multi-source vehicles is currently a research hotspot. However, it is an open ...The utilization of traffic information received from intelligent vehicle highway systems(IVHS) to plan velocity and split output power for multi-source vehicles is currently a research hotspot. However, it is an open issue to plan vehicle velocity and distribute output power between different supply units simultaneously due to the strongly coupling characteristic of the velocity planning and the power distribution. To address this issue, a flexible predictive power-split control strategy based on IVHS is proposed for electric vehicles(EVs) equipped with battery-supercapacitor system(BSS). Unlike hierarchical strategies to plan vehicle velocity and distribute output power separately, a monolayer model predictive control(MPC) method is employed to optimize them online at the same time. Firstly, a flexible velocity planning strategy is designed based on the signal phase and time(SPAT) information received from IVHS and then the Pontryagin’s minimum principle(PMP) is adopted to formulate the optimal control problem of the BSS. Then, the flexible velocity planning strategy and the optimal control problem of BSS are embedded into an MPC framework, which is online solved using the shooting method in a fashion of receding horizon. Simulation results verify that the proposed strategy achieves a superior performance compared with the hierarchical strategy in terms of transportation efficiency, battery capacity loss, energy consumption and computation time.展开更多
A mathematical optimal-control tumor therapy framework consisting of radio- and anti-angiogenesis control strategies that are included in a tumor growth model is investigated. The governing system, resulting from the ...A mathematical optimal-control tumor therapy framework consisting of radio- and anti-angiogenesis control strategies that are included in a tumor growth model is investigated. The governing system, resulting from the combination of two well established models, represents the differential constraint of a non-smooth optimal control problem that aims at reducing the volume of the tumor while keeping the radio- and anti-angiogenesis chemical dosage to a minimum. Existence of optimal solutions is proved and necessary conditions are formulated in terms of the Pontryagin maximum principle. Based on this principle, a so-called sequential quadratic Hamiltonian (SQH) method is discussed and benchmarked with an “interior point optimizer—a mathematical programming language” (IPOPT-AMPL) algorithm. Results of numerical experiments are presented that successfully validate the SQH solution scheme. Further, it is shown how to choose the optimisation weights in order to obtain treatment functions that successfully reduce the tumor volume to zero.展开更多
This article presents the Parametric Iteration Method (PIM) for finding optimal control and its corresponding trajectory of linear systems. Without any discretization or transformation, PIM provides a sequence of func...This article presents the Parametric Iteration Method (PIM) for finding optimal control and its corresponding trajectory of linear systems. Without any discretization or transformation, PIM provides a sequence of functions which converges to the exact solution of problem. Our emphasis will be on an auxiliary parameter which directly affects on the rate of convergence. Comparison of PIM and the Variational Iteration Method (VIM) is given to show the preference of PIM over VIM. Numerical results are given for several test examples to demonstrate the applicability and efficiency of the method.展开更多
This paper examines optimal control of transmission dynamics of Mycobacterium ulceran (MU) infection. A nonlinear mathematical model for the problem is proposed and analysed qualitatively using the stability theory of...This paper examines optimal control of transmission dynamics of Mycobacterium ulceran (MU) infection. A nonlinear mathematical model for the problem is proposed and analysed qualitatively using the stability theory of the differential equations, optimal control and computer simulation. The basic reproduction number of the reduced model system is obtained by using the next generation operator method. It is found that by using Ruth Hurwitz criteria, the disease free equilibrium point is locally asymptotically stable and using centre manifold theory, the model shows the transcritical (forward) bifurcation. Optimal control is applied to the model seeking to minimize the transmission dynamics of MU infection on human and water-bugs. Pontryagin’s maximum principle is used to characterize the optimal levels of the controls. The results of optimality are solved numerically using MATLAB software and the results show that optimal combination of two controls (environmental and health education for prevention) and (water and environmental purification) minimizes the MU infection in the population.展开更多
Listeriosis is an illness caused by the germ</span><i><span style="font-family:Verdana;"> <i>Listeria</i> <i>monocytogenes</i></span></i><span style=&...Listeriosis is an illness caused by the germ</span><i><span style="font-family:Verdana;"> <i>Listeria</i> <i>monocytogenes</i></span></i><span style="font-family:Verdana;">. Generally, humans are infected with listeriosis after eating contaminated food. Listeriosis mostly affects people with weakened immune systems, pregnant women and newborns. In this paper, a model describing the dynamics o</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">f Listeriosis is developed and analysed using ordinary differential equations. The model was analysed both quantitatively and qualitatively for its local and global stability, basic reproductive number and parameter contributions to the basic reproductive number to understand the impact of each parameter on the disease spread. The Listeriosis model has been extended to include time dependent control variables such as treatment of both humans and animals, vaccination and education of humans. Pontryagin</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">’</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s Maximum Principle was introduced to obtain the best optimal control strategies required for curbing Listeriosis infections. Numerical simulation was performed and the results displayed graphically and discussed. Cost effectiveness analysis was conducted using the intervention averted ratio (IAR) concepts and it was revealed that the most effective intervention strategy is the treatment of infect</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ed</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> humans and animals.展开更多
The optimal use of intervention strategies to mitigate the spread of Nipah Virus (NiV) using optimal control technique is studied in this paper. First of all we formulate a dynamic model of NiV infections with variabl...The optimal use of intervention strategies to mitigate the spread of Nipah Virus (NiV) using optimal control technique is studied in this paper. First of all we formulate a dynamic model of NiV infections with variable size population and two control strategies where creating awareness and treatment are considered as controls. We intend to find the optimal combination of these two control strategies that will minimize the cost of the two control measures and as a result the number of infectious individuals will decrease. We establish the existence for the optimal controls and Pontryagin’s maximum principle is used to characterize the optimal controls. The numerical simulation suggests that optimal control technique is much more effective to minimize the infected individuals and the corresponding cost of the two controls. It is also monitored that in the case of high contact rate, controls have to work for longer period of time to get the desired result. Numerical simulation reveals that the spread of Nipah virus can be controlled effectively if we apply control strategy at early stage.展开更多
This paper is concerned with periodic optimal control problems governed by semi- linear parabolic differential equations with impulse control. Pontryagin's maximum principle is derived. The proofs rely on a unique co...This paper is concerned with periodic optimal control problems governed by semi- linear parabolic differential equations with impulse control. Pontryagin's maximum principle is derived. The proofs rely on a unique continuation estimate at one time for a linear parabolic equation.展开更多
In this paper, we consider a leptospirosis epidemic model to implement optimal campaign by using multiple control variables. First, we show the existence of the control problem. Then we derive the conditions under whi...In this paper, we consider a leptospirosis epidemic model to implement optimal campaign by using multiple control variables. First, we show the existence of the control problem. Then we derive the conditions under which it is optimal to eradicate the leptospirosis infection and examine the impact of a possible educatioal/vaccinaction campaign using Pontryagin’s Maximum Principle. We completely characterize the optimal control problem and compute the numerical solution of the optimality system using an iterative method. The results obtained from the numerical simulations of the model show that a possible educational/vaccinaction combined with effective treatment regime would reduce the spread of the leptospirosis infection appreciably.展开更多
In this paper, we propose and analyze a mathematical model to study the dynamics of a fishery resource system with stage structure in an aquatic environment that consists of two zones namely unreserved zone (fishing p...In this paper, we propose and analyze a mathematical model to study the dynamics of a fishery resource system with stage structure in an aquatic environment that consists of two zones namely unreserved zone (fishing permitted) and reserved zone (fishing is strictly prohibited). In this model we introduce a stage structure in which predators are split into two kinds as immature predators and mature predators. It is assumed that immature predators cannot catch the prey and their foods are given by their parents (mature predators). It is also assumed that the fishing of immature predators prohibited in the unreserved zone and predator species are not allowed to enter inside the reserved zone. The local and global stability analysis has been specified. Biological and Bionomical equilibriums of the system are derived. Mathematical formulation of the optimal harvesting policy is given and its solution is derived in the equilibrium case by using Pontryagin’s maximum principle.展开更多
Heterogeneous wireless sensor networks(HWSNs)are vulnerable to malware propagation,because of their low configuration and weak defense mechanism.Therefore,an optimality system for HWSNs is developed to suppress malwar...Heterogeneous wireless sensor networks(HWSNs)are vulnerable to malware propagation,because of their low configuration and weak defense mechanism.Therefore,an optimality system for HWSNs is developed to suppress malware propagation in this paper.Firstly,a heterogeneous-susceptible-exposed-infectious-recovered-susceptible(HSEIRS)model is proposed to describe the state dynamics of heterogeneous sensor nodes(HSNs)in HWSNs.Secondly,the existence of an optimal control problem with installing antivirus on HSNs to minimize the sum of the cumulative infection probabilities of HWSNs at a low cost based on the HSEIRS model is proved,and then an optimal control strategy for the problem is derived by the optimal control theory.Thirdly,the optimal control strategy based on the HSEIRS model is transformed into corresponding Hamiltonian by the Pontryagin’s minimum principle,and the corresponding optimality system is derived.Finally,the effectiveness of the optimality system is validated by the experimental simulations,and the results show that the infectious HSNs will fall to an extremely low level at a low cost.展开更多
The implementation of optimal control strategies involving preventive measures and antiviral treatment can significantly reduce the number of clinical cases of influenza. In this paper, a model for the transmission dy...The implementation of optimal control strategies involving preventive measures and antiviral treatment can significantly reduce the number of clinical cases of influenza. In this paper, a model for the transmission dynamics of influenza is formulated and two control strategies involving preventive measures (awareness campaign, washing hand, using hand sanitizer, wearing mask) and treatment are considered and used to minimize the total number of infected individuals and associated cost of using these two controls. The resulting optimality system is solved numerically. Hamiltonian is formulated to investigate the existence of the optimal control, in the optimal control model. Pontryagin’s Maximum Principle is applied to describe the control variables and the objective function is designed to reduce both the infection and the cost of interventions. From the numerical simulation, it is observed that in the case of high contact rate (β = 3), both the controls work for a longer period of time to reduce the disease burden. The optimal control analysis and numerical simulations reveal that the interventions reduce the number of exposed and infected individuals.展开更多
The purpose of this paper is to introduce to you, the Western people, nowadays a “widely unknown” Japanese thermodynamicist by the name of Motoyosi Sugita and his study on the thermodynamics of transient phenomena a...The purpose of this paper is to introduce to you, the Western people, nowadays a “widely unknown” Japanese thermodynamicist by the name of Motoyosi Sugita and his study on the thermodynamics of transient phenomena and his theory of life. This is because although he was one of the top theoretical physicists in Japan before, during and after WWII and after WWII he promoted the establishment of the biophysical society of Japan as one of the founding members, he himself and his studies themselves have seemed to be totally forgotten nowadays in spite that his study was absolutely important for the study of life. Therefore, in this paper I would like to present what kind of person he was and what he studied in physics as a review on the physics work of Motoyosi Sugita for the first time. I will follow his past studies to introduce his ideas in theoretical physics as well as in biophysics as follows: He proposed the bright ideas such as the quasi-static change in the broad sense, the virtual heat, and the field of chemical potential etc. in order to establish his own theory of thermodynamics of transient phenomena, as the generalization of the Onsager-Prigogine’s theory of the irreversible processes. By the concept of the field of chemical potential that acquired the nonlinear transport, he was seemingly successful to exceed and go beyond the scope of Onsager and Prigogine. Once he established his thermodynamics, he explored the existence of the 4th law of thermodynamics for the foundation of theory of life. He applied it to broad categories of transient phenomena including life and life being such as the theory of metabolism. He regarded the 4th law of thermodynamics as the maximum principle in transient phenomena. He tried to prove it all life long. Since I have recently found that his maximum principle can be included in more general maximum principle, which was known as the Pontryagin’s maximum principle in the theory of optimal control, I would like to explain such theories produced by Motoyosi Sugita as detailed as possible. And also I have put short history of Motoyosi Sugita’s personal life in order for you to know him well. I hope that this article helps you to know this wonderful man and understand what he did in the past, which was totally forgotten in the world and even in Japan.展开更多
In this paper, we attempt to give a unified approach to the existing several versions of Ekeland's variational principle. In the framework of uniiorm spaces, we introduce p-distances and more generally, q-distances....In this paper, we attempt to give a unified approach to the existing several versions of Ekeland's variational principle. In the framework of uniiorm spaces, we introduce p-distances and more generally, q-distances. Then we introduce a new type of completeness for uniform spaces, i.e., sequential completeness with respect to a q-distance (particularly, a p-distance), which is a very extensive concept of completeness. By using q-distances and the new type of completeness, we prove a generalized Takahashi's nonconvex minimization theorem, a generalized Ekeland's variational principle and a generalized Caristi's fixed point theorem. Moreover, we show that the above three theorems are equivalent to each other. From the generalized Ekeland's variational principle, we deduce a number of particular versions of Ekeland's principle, which include many known versions of the principle and their improvements.展开更多
In this paper, by using p-distances on uniform spaces, we establish a general vectorial Ekeland variational principle (in short EVP), where the objective function is defined on a uniform space and taking values in a...In this paper, by using p-distances on uniform spaces, we establish a general vectorial Ekeland variational principle (in short EVP), where the objective function is defined on a uniform space and taking values in a pre-ordered real linear space and the perturbation involves a p-distance and a monotone function of the objective function. Since p-distances are very extensive, such a form of the perturbation in deed contains many different forms of perturbations appeared in the previous versions of EVP. Besides, we only require the objective function has a very weak property, as a substitute for lower semi-continuity, and only require the domain space (which is a uniform space) has a very weak type of completeness, i.e., completeness with respect to a certain p-distance. Such very weak type of completeness even includes local completeness when the uniform space is a locally convex topological vector space. From the general vectorial EVP, we deduce a general vectorial Caristi's fixed point theorem and a general vectorial Takahashi's nonconvex minimization theorem. Moreover, we show that the above three theorems are equivalent to each other. We see that the above general vectorial EVP includes many particular versions of EVP, which extend and complement the related known results.展开更多
文摘In this paper we investigate optimal control problems governed by a advection-diffusion-reaction equation. We present a method for deriving conditions in the form of Pontryagin’s principle. The main tools used are the Ekeland’s variational principle combined with penalization and spike variation techniques.
基金Supported by the National Natural Science Foundation of China(10871141)
文摘By using the properties of w-distances and Gerstewitz's functions, we first give a vectorial Takahashi's nonconvex minimization theorem with a w-distance. From this, we deduce a general vectorial Ekeland's variational principle, where the objective function is from a complete metric space into a pre-ordered topological vector space and the perturbation contains a w-distance and a non-decreasing function of the objective function value. From the general vectorial variational principle, we deduce a vectorial Caristfs fixed point theorem with a w-distance. Finally we show that the above three theorems are equivalent to each other. The related known results are generalized and improved. In particular, some conditions in the theorems of [Y. Araya, Ekeland's variational principle and its equivalent theorems in vector optimization, J. Math. Anal. Appl. 346(2008), 9-16] are weakened or even completely relieved.
基金Supported by International Technology Cooperation Program of Science and Technology Commission of Shanghai Municipality of China(Grant No.21160710600)National Nature Science Foundation of China(Grant No.52372393)Shanghai Pujiang Program of China(Grant No.21PJD075).
文摘Fuel consumption is one of the main concerns for heavy-duty trucks.Predictive cruise control(PCC)provides an intriguing opportunity to reduce fuel consumption by using the upcoming road information.In this study,a real-time implementable PCC,which simultaneously optimizes engine torque and gear shifting,is proposed for heavy-duty trucks.To minimize fuel consumption,the problem of the PCC is formulated as a nonlinear model predictive control(MPC),in which the upcoming road elevation information is used.Finding the solution of the nonlinear MPC is time consuming;thus,a real-time implementable solver is developed based on Pontryagin’s maximum principle and indirect shooting method.Dynamic programming(DP)algorithm,as a global optimization algorithm,is used as a performance benchmark for the proposed solver.Simulation,hardware-in-the-loop and real-truck experiments are conducted to verify the performance of the proposed controller.The results demonstrate that the MPC-based solution performs nearly as well as the DP-based solution,with less than 1%deviation for testing roads.Moreover,the proposed co-optimization controller is implementable in a real-truck,and the proposed MPC-based PCC algorithm achieves a fuel-saving rate of 7.9%without compromising the truck’s travel time.
基金supported by the National Natural Science Foundation of China (62173303)the Fundamental Research for the Zhejiang P rovincial Universities (RF-C2020003)。
文摘The utilization of traffic information received from intelligent vehicle highway systems(IVHS) to plan velocity and split output power for multi-source vehicles is currently a research hotspot. However, it is an open issue to plan vehicle velocity and distribute output power between different supply units simultaneously due to the strongly coupling characteristic of the velocity planning and the power distribution. To address this issue, a flexible predictive power-split control strategy based on IVHS is proposed for electric vehicles(EVs) equipped with battery-supercapacitor system(BSS). Unlike hierarchical strategies to plan vehicle velocity and distribute output power separately, a monolayer model predictive control(MPC) method is employed to optimize them online at the same time. Firstly, a flexible velocity planning strategy is designed based on the signal phase and time(SPAT) information received from IVHS and then the Pontryagin’s minimum principle(PMP) is adopted to formulate the optimal control problem of the BSS. Then, the flexible velocity planning strategy and the optimal control problem of BSS are embedded into an MPC framework, which is online solved using the shooting method in a fashion of receding horizon. Simulation results verify that the proposed strategy achieves a superior performance compared with the hierarchical strategy in terms of transportation efficiency, battery capacity loss, energy consumption and computation time.
文摘A mathematical optimal-control tumor therapy framework consisting of radio- and anti-angiogenesis control strategies that are included in a tumor growth model is investigated. The governing system, resulting from the combination of two well established models, represents the differential constraint of a non-smooth optimal control problem that aims at reducing the volume of the tumor while keeping the radio- and anti-angiogenesis chemical dosage to a minimum. Existence of optimal solutions is proved and necessary conditions are formulated in terms of the Pontryagin maximum principle. Based on this principle, a so-called sequential quadratic Hamiltonian (SQH) method is discussed and benchmarked with an “interior point optimizer—a mathematical programming language” (IPOPT-AMPL) algorithm. Results of numerical experiments are presented that successfully validate the SQH solution scheme. Further, it is shown how to choose the optimisation weights in order to obtain treatment functions that successfully reduce the tumor volume to zero.
文摘This article presents the Parametric Iteration Method (PIM) for finding optimal control and its corresponding trajectory of linear systems. Without any discretization or transformation, PIM provides a sequence of functions which converges to the exact solution of problem. Our emphasis will be on an auxiliary parameter which directly affects on the rate of convergence. Comparison of PIM and the Variational Iteration Method (VIM) is given to show the preference of PIM over VIM. Numerical results are given for several test examples to demonstrate the applicability and efficiency of the method.
文摘This paper examines optimal control of transmission dynamics of Mycobacterium ulceran (MU) infection. A nonlinear mathematical model for the problem is proposed and analysed qualitatively using the stability theory of the differential equations, optimal control and computer simulation. The basic reproduction number of the reduced model system is obtained by using the next generation operator method. It is found that by using Ruth Hurwitz criteria, the disease free equilibrium point is locally asymptotically stable and using centre manifold theory, the model shows the transcritical (forward) bifurcation. Optimal control is applied to the model seeking to minimize the transmission dynamics of MU infection on human and water-bugs. Pontryagin’s maximum principle is used to characterize the optimal levels of the controls. The results of optimality are solved numerically using MATLAB software and the results show that optimal combination of two controls (environmental and health education for prevention) and (water and environmental purification) minimizes the MU infection in the population.
文摘Listeriosis is an illness caused by the germ</span><i><span style="font-family:Verdana;"> <i>Listeria</i> <i>monocytogenes</i></span></i><span style="font-family:Verdana;">. Generally, humans are infected with listeriosis after eating contaminated food. Listeriosis mostly affects people with weakened immune systems, pregnant women and newborns. In this paper, a model describing the dynamics o</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">f Listeriosis is developed and analysed using ordinary differential equations. The model was analysed both quantitatively and qualitatively for its local and global stability, basic reproductive number and parameter contributions to the basic reproductive number to understand the impact of each parameter on the disease spread. The Listeriosis model has been extended to include time dependent control variables such as treatment of both humans and animals, vaccination and education of humans. Pontryagin</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">’</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">s Maximum Principle was introduced to obtain the best optimal control strategies required for curbing Listeriosis infections. Numerical simulation was performed and the results displayed graphically and discussed. Cost effectiveness analysis was conducted using the intervention averted ratio (IAR) concepts and it was revealed that the most effective intervention strategy is the treatment of infect</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">ed</span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;"> humans and animals.
文摘The optimal use of intervention strategies to mitigate the spread of Nipah Virus (NiV) using optimal control technique is studied in this paper. First of all we formulate a dynamic model of NiV infections with variable size population and two control strategies where creating awareness and treatment are considered as controls. We intend to find the optimal combination of these two control strategies that will minimize the cost of the two control measures and as a result the number of infectious individuals will decrease. We establish the existence for the optimal controls and Pontryagin’s maximum principle is used to characterize the optimal controls. The numerical simulation suggests that optimal control technique is much more effective to minimize the infected individuals and the corresponding cost of the two controls. It is also monitored that in the case of high contact rate, controls have to work for longer period of time to get the desired result. Numerical simulation reveals that the spread of Nipah virus can be controlled effectively if we apply control strategy at early stage.
基金partially supported by the National Science Foundation of China(11371285)
文摘This paper is concerned with periodic optimal control problems governed by semi- linear parabolic differential equations with impulse control. Pontryagin's maximum principle is derived. The proofs rely on a unique continuation estimate at one time for a linear parabolic equation.
文摘In this paper, we consider a leptospirosis epidemic model to implement optimal campaign by using multiple control variables. First, we show the existence of the control problem. Then we derive the conditions under which it is optimal to eradicate the leptospirosis infection and examine the impact of a possible educatioal/vaccinaction campaign using Pontryagin’s Maximum Principle. We completely characterize the optimal control problem and compute the numerical solution of the optimality system using an iterative method. The results obtained from the numerical simulations of the model show that a possible educational/vaccinaction combined with effective treatment regime would reduce the spread of the leptospirosis infection appreciably.
文摘In this paper, we propose and analyze a mathematical model to study the dynamics of a fishery resource system with stage structure in an aquatic environment that consists of two zones namely unreserved zone (fishing permitted) and reserved zone (fishing is strictly prohibited). In this model we introduce a stage structure in which predators are split into two kinds as immature predators and mature predators. It is assumed that immature predators cannot catch the prey and their foods are given by their parents (mature predators). It is also assumed that the fishing of immature predators prohibited in the unreserved zone and predator species are not allowed to enter inside the reserved zone. The local and global stability analysis has been specified. Biological and Bionomical equilibriums of the system are derived. Mathematical formulation of the optimal harvesting policy is given and its solution is derived in the equilibrium case by using Pontryagin’s maximum principle.
基金National Natural Science Foundation of China(No.61772018)Zhejiang Provincial Natural Science Foundation of China(No.LZ22F020002)。
文摘Heterogeneous wireless sensor networks(HWSNs)are vulnerable to malware propagation,because of their low configuration and weak defense mechanism.Therefore,an optimality system for HWSNs is developed to suppress malware propagation in this paper.Firstly,a heterogeneous-susceptible-exposed-infectious-recovered-susceptible(HSEIRS)model is proposed to describe the state dynamics of heterogeneous sensor nodes(HSNs)in HWSNs.Secondly,the existence of an optimal control problem with installing antivirus on HSNs to minimize the sum of the cumulative infection probabilities of HWSNs at a low cost based on the HSEIRS model is proved,and then an optimal control strategy for the problem is derived by the optimal control theory.Thirdly,the optimal control strategy based on the HSEIRS model is transformed into corresponding Hamiltonian by the Pontryagin’s minimum principle,and the corresponding optimality system is derived.Finally,the effectiveness of the optimality system is validated by the experimental simulations,and the results show that the infectious HSNs will fall to an extremely low level at a low cost.
文摘The implementation of optimal control strategies involving preventive measures and antiviral treatment can significantly reduce the number of clinical cases of influenza. In this paper, a model for the transmission dynamics of influenza is formulated and two control strategies involving preventive measures (awareness campaign, washing hand, using hand sanitizer, wearing mask) and treatment are considered and used to minimize the total number of infected individuals and associated cost of using these two controls. The resulting optimality system is solved numerically. Hamiltonian is formulated to investigate the existence of the optimal control, in the optimal control model. Pontryagin’s Maximum Principle is applied to describe the control variables and the objective function is designed to reduce both the infection and the cost of interventions. From the numerical simulation, it is observed that in the case of high contact rate (β = 3), both the controls work for a longer period of time to reduce the disease burden. The optimal control analysis and numerical simulations reveal that the interventions reduce the number of exposed and infected individuals.
文摘The purpose of this paper is to introduce to you, the Western people, nowadays a “widely unknown” Japanese thermodynamicist by the name of Motoyosi Sugita and his study on the thermodynamics of transient phenomena and his theory of life. This is because although he was one of the top theoretical physicists in Japan before, during and after WWII and after WWII he promoted the establishment of the biophysical society of Japan as one of the founding members, he himself and his studies themselves have seemed to be totally forgotten nowadays in spite that his study was absolutely important for the study of life. Therefore, in this paper I would like to present what kind of person he was and what he studied in physics as a review on the physics work of Motoyosi Sugita for the first time. I will follow his past studies to introduce his ideas in theoretical physics as well as in biophysics as follows: He proposed the bright ideas such as the quasi-static change in the broad sense, the virtual heat, and the field of chemical potential etc. in order to establish his own theory of thermodynamics of transient phenomena, as the generalization of the Onsager-Prigogine’s theory of the irreversible processes. By the concept of the field of chemical potential that acquired the nonlinear transport, he was seemingly successful to exceed and go beyond the scope of Onsager and Prigogine. Once he established his thermodynamics, he explored the existence of the 4th law of thermodynamics for the foundation of theory of life. He applied it to broad categories of transient phenomena including life and life being such as the theory of metabolism. He regarded the 4th law of thermodynamics as the maximum principle in transient phenomena. He tried to prove it all life long. Since I have recently found that his maximum principle can be included in more general maximum principle, which was known as the Pontryagin’s maximum principle in the theory of optimal control, I would like to explain such theories produced by Motoyosi Sugita as detailed as possible. And also I have put short history of Motoyosi Sugita’s personal life in order for you to know him well. I hope that this article helps you to know this wonderful man and understand what he did in the past, which was totally forgotten in the world and even in Japan.
基金Supported by National Natural Science Foundation of China(Grant No.10871141)
文摘In this paper, we attempt to give a unified approach to the existing several versions of Ekeland's variational principle. In the framework of uniiorm spaces, we introduce p-distances and more generally, q-distances. Then we introduce a new type of completeness for uniform spaces, i.e., sequential completeness with respect to a q-distance (particularly, a p-distance), which is a very extensive concept of completeness. By using q-distances and the new type of completeness, we prove a generalized Takahashi's nonconvex minimization theorem, a generalized Ekeland's variational principle and a generalized Caristi's fixed point theorem. Moreover, we show that the above three theorems are equivalent to each other. From the generalized Ekeland's variational principle, we deduce a number of particular versions of Ekeland's principle, which include many known versions of the principle and their improvements.
基金Supported by National Natural Science Foundation of China (Grant No. 10871141)
文摘In this paper, by using p-distances on uniform spaces, we establish a general vectorial Ekeland variational principle (in short EVP), where the objective function is defined on a uniform space and taking values in a pre-ordered real linear space and the perturbation involves a p-distance and a monotone function of the objective function. Since p-distances are very extensive, such a form of the perturbation in deed contains many different forms of perturbations appeared in the previous versions of EVP. Besides, we only require the objective function has a very weak property, as a substitute for lower semi-continuity, and only require the domain space (which is a uniform space) has a very weak type of completeness, i.e., completeness with respect to a certain p-distance. Such very weak type of completeness even includes local completeness when the uniform space is a locally convex topological vector space. From the general vectorial EVP, we deduce a general vectorial Caristi's fixed point theorem and a general vectorial Takahashi's nonconvex minimization theorem. Moreover, we show that the above three theorems are equivalent to each other. We see that the above general vectorial EVP includes many particular versions of EVP, which extend and complement the related known results.