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Highly efficient solution-processed CZTSSe solar cells based on a convenient sodium-incorporated post-treatment method 被引量:9
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作者 Biwen Duan Linbao Guo +7 位作者 Qing Yu Jiangjian Shi Huijue Wu Yanhong Luo Dongmei Li Sixin Wu Zhi Zheng Qingbo Meng 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2020年第1期196-203,I0007,共9页
In CZTSSe solar cells,a simple sodium-incorporation post-treatment method toward solution-processed Cu2Zn Sn S4precursor films is presented in this work.An ultrathin NaCl film is deposited on Cu2Zn Sn S4precursor film... In CZTSSe solar cells,a simple sodium-incorporation post-treatment method toward solution-processed Cu2Zn Sn S4precursor films is presented in this work.An ultrathin NaCl film is deposited on Cu2Zn Sn S4precursor films by spin-coating NaCl solution.In subsequent selenization process,the introduction of Na Cl is found to be benefacial for the formation of Cu2-xSe,which can further facilitate the element transportation,leading to dense and smooth CZTSSe films with large grains and less impurity Cu2Sn(S,Se)3phase.SIMS depth profiles confirm the gradient distribution of the sodium element in Na-doped absorbers.Photoluminescence spectra show that the introduction of appropriate sodium into the absorber can inhibit the band tail states.As high as 11.18% of power conversion efficiency(PCE)is achieved for the device treated with 5 mg mL^-1 NaCl solution,and an average efficiency of Na-doped devices is 10.71%,13%higher than that of the control groups(9.45%).Besides,the depletion width and the charge recombination lifetime can also have regular variation with sodium treatment.This work offers an easy modification method for high-quality Na-doped CZTSSe films and high-performance devices,in the meantime,it can also help to further understand the effects of sodium in CZTSSe solar cells. 展开更多
关键词 Thin film solar cell CZTSSe Sodium doping post-treatment Spin-coating method
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Comparison of pre-treatment and post-treatment use of selenium in retinal ischemia reperfusion injury 被引量:3
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作者 Alper Yazici Hasan Aksit +6 位作者 Esin Sogutlu Sari Arzu Yay Haydar Ali Erken Dilek Aksit Harun Cakmak Kamil Seyrek Sitki Samet Ermis 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2015年第2期263-268,共6页
AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion(IR) model and compare pretreatment and post-treatment use.METHODS: Selenium pre-treatment group(n =8) was treated with intraperitoneal(i.... AIM: To investigate the effects of selenium in rat retinal ischemia reperfusion(IR) model and compare pretreatment and post-treatment use.METHODS: Selenium pre-treatment group(n =8) was treated with intraperitoneal(i.p.) selenium 0.5 mg/kg for7 d and terminated 24 h after the IR injury. Selenium posttreatment group( n = 8) was treated with i. p. selenium0.5 mg/kg for 7d after the IR injury with termination at the end of the 7d period. Sham group(n =8) received i.p.saline injections identical to the selenium volume for 7d with termination 24 h after the IR injury. Control group(n =8) received no intervention. Main outcome measures were retina superoxide dismutase(SOD), glutathione(GSH),total antioxidant status(TAS), malondialdehyde(MDA),DNA fragmentation levels, and immunohistological apoptosis evaluation.RESULTS: Compared to the Sham group, selenium pre-treatment had a statistical difference in all parameters except SOD. Post-treatment selenium also resulted in statistical differences in all parameters except the MDA levels. When comparing selenium groups, the pre-treatment selenium group had a statistically higher success in reduction of markers of cell damage such as MDA and DNA fragmentation. In contrast, the post-selenium treatment group had resulted in statisticallyhigher levels of GSH. Histologically both selenium groups succeeded to limit retinal thickening and apoptosis. Pre-treatment use was statistically more successful in decreasing apoptosis in ganglion cell layer compared to post-treatment use.CONCLUSION: Selenium was successful in retinal protection in IR injuries. Pre-treatment efficacy was superior in terms of prevention of tissue damage and apoptosis. 展开更多
关键词 RETINA SELENIUM ISCHEMIA-REPERFUSION APOPTOSIS pre-treatment post-treatment oxidative stress
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Influence of the post-treatment of HZSM-5 zeolite on catalytic performance for alkylation of benzene with methanol 被引量:17
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作者 Qingtao Wang Wenwen Han +5 位作者 Hualei Hu Jinghui Lyu Xiaolong Xu Qunfeng Zhang Hongjing Wang Xiaonian Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2017年第12期1777-1783,共7页
The porous material HZSM-5 zeolite with micro-mesopore hierarchical porosity was prepared by post-treatment (combined alkali treatment and acid leaching) of parent zeolite and its catalytic performance for benzene a... The porous material HZSM-5 zeolite with micro-mesopore hierarchical porosity was prepared by post-treatment (combined alkali treatment and acid leaching) of parent zeolite and its catalytic performance for benzene alkylation with methanol was investigated. The effect of post-treatment on the textural properties was characterized by various techniques (including ICP-AES, XRD, nitrogen sorption isotherms, SEM, NH3-TPD, Py-IR and TG). The results indicated that the post-treatment could modify the structural and acidic properties of HZSM-5 zeolite. In this procedure, not only additional mesopores were created by selective extraction of silicon but also the acidity was tuned. Consequently, the modified HZSM-5 zeolite showed larger external surface area with less acid sites as compared to the parent zeolite. It was found out that the modified zeolite exhibited a higher benzene conversion and xylene selectivity for alkylation of benzene with methanol as well as excellent life span of the catalyst than conventional ones. This can be explained by the facts that the presence of additional mesopores improved the diffusion property in the reactions. Furthermore, the modified zeolite showed an appropriate Bronsted acidity for effective suppression of the side reaction of methanol to olefins, thus reduced the accumulation of coke on the HZSM-5 zeolite, which was favorable for the catalyst stability. In comparison with the parent HZSM-5 zeolite, the modified zeolite by alkali treatment and acid leaching showed better performance for the benzene alkylation with methanol. 展开更多
关键词 HZSM-5 zeolite Hierarchical porosity post-treatment Benzene alkylation with methanol
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Curcumin pretreatment and post-treatment both improve the antioxidative ability of neurons with oxygen-glucose deprivation 被引量:8
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作者 Jing-xian Wu Lu-yu Zhang +3 位作者 Yan-lin Chen Shan-shan Yu Yong Zhao Jing Zhao 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第3期481-489,共9页
Recent studies have shown that induced expression of endogenous antioxidative enzymes thr- ough activation of the antioxidant response element/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway may be a neur... Recent studies have shown that induced expression of endogenous antioxidative enzymes thr- ough activation of the antioxidant response element/nuclear factor erythroid 2-related factor 2 (Nrf2) pathway may be a neuroprotective strategy. In this study, rat cerebral cortical neurons cultured in vitro were pretreated with 10 ktM curcumin or post-treated with 5 pM curcumin, respectively before or after being subjected to oxygen-glucose deprivation and reoxygenation for 24 hours. Both pretreatment and post-treatment resulted in a significant decrease of cell injury as indicated by propidium iodide/Hoechst 33258 staining, a prominent increase of Nrf2 protein expression as indicated by western blot analysis, and a remarkable increase of protein expression and enzyme activity in whole cell lysates of thioredoxin before ischemia, after ischemia, and after reoxygenation. In addition, post-treatment with curcumin inhibited early DNA/RNA oxidation as indicated by immunocytochemistry and increased nuclear Nrf2 protein by inducing nuclear accumulation of Nrf2. These findings suggest that curcumin activates the expression of thi- oredoxin, an antioxidant protein in the Nrf2 pathway, and protects neurons from death caused by oxygen-glucose deprivation in an in vitro model of ischemia/reperfusion. We speculate that pharmacologic stimulation of antioxidant gene expression may be a promising approach to neu- roprotection after cerebral ischemia. 展开更多
关键词 nerve regeneration brain injury CURCUMIN ischemia/reperfusion injury OXIDATIVESTRESS primary cell culture cortical neurons oxygen-glucose deprivation PRETREATMENT post-treatment NSFC grant neural regeneration
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Post-treatment of TS-1 with Mixtures of TPAOH and Ammonium Salts and the Catalytic Properties in Propylene Epoxidation 被引量:1
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作者 Yaquan Wang Xinpeng Han +1 位作者 Haoyang Li Xiao Wang 《Transactions of Tianjin University》 EI CAS 2018年第5期461-470,共10页
TS-1/SiO_2 extrudate was post-treated with mixed solution of tetrapropyl ammonium hydroxide(TPAOH)and various ammonium salts solution(NH_4F,(NH_4)_3PO_4,(NH_4)_2CO_3,(NH_4)_2SO_4,NH_4CH_3CO_2,NH_4NO_3,NH_4Cl and(NH_4)... TS-1/SiO_2 extrudate was post-treated with mixed solution of tetrapropyl ammonium hydroxide(TPAOH)and various ammonium salts solution(NH_4F,(NH_4)_3PO_4,(NH_4)_2CO_3,(NH_4)_2SO_4,NH_4CH_3CO_2,NH_4NO_3,NH_4Cl and(NH_4)_2TiF_6).The obtained hierarchical TS-1 catalysts were characterized by many techniques and tested for propylene epoxidation using hydrogen peroxide as an oxidant in a fixed-bed reactor.It was shown that the physicochemical and catalytic properties of the treated TS-1/SiO_2 extrudate depended on the types of ammonium salts added.Compared to the treatment with TPAOH alone,the treatment with a mixed solution of TPAOH and some ammonium salts can greatly improve the catalytic properties of the treated TS-1/SiO_2 extrudate.Some of these ammonium salts were favorable for the incorporation of titanium in the framework,and the beneficial effect depended on the types of ammonium salt.TS-1/SiO_2 extrudate treated with a mixed solution of TPAOH and(NH_4)_3PO_4 exhibited the highest catalyst stability in propylene epoxidation.Such catalytic property can be correlated to high crystallinity,more framework titanium,large specific surface area and large external surface area. 展开更多
关键词 AMMONIUM SALT post-treatment Catalyst stability TS-1/SiO2 EXTRUDATE EPOXIDATION
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Effect of Post-Treatment Conditions on the Inactivation of MS2 Bacteriophage as Indicator for Pathogenic Viruses after the Composting Process 被引量:1
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作者 Hamidatu S. Darimani Ryusei Ito +1 位作者 Naoyuki Funamizu Amadou H. Maiga 《Journal of Agricultural Chemistry and Environment》 2018年第2期73-80,共8页
A rural model composting toilet system still had some pathogens in the compost after months of operation and hence requires a post-treatment. The aim of the study was to sanitize compost withdrawn from the composting ... A rural model composting toilet system still had some pathogens in the compost after months of operation and hence requires a post-treatment. The aim of the study was to sanitize compost withdrawn from the composting toilet by setting post-treatment conditions. The kinetics inactivation of MS2 bacteriophage, selected as indicator for pathogenic viruses were determined during post-treatment at different temperatures (30°C, 40°C and 50°C) with varying moisture contents (50%, 60% and 70%). As a result, the inactivation rates during the post-treatment were 0.093 - 0.020 h-1, 0.025 - 0.088 h1, 0.447 - 0.100 h-1 at 30°C, 40°C and 50°C respectively. The inactivation rate coefficient (k) values of MS2 bacteriophage depended on higher temperature but not on moisture content. 展开更多
关键词 COMPOSTING TOILET MS2 BACTERIOPHAGE Temperature Moisture Content post-treatment
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Heat Post-Treatment to Reduce Thickness Swelling of Particleboard from Fast-Growing Poplars
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作者 濮安彬 陆仁书 +1 位作者 张显全 王伟宏 《Journal of Forestry Research》 SCIE CAS CSCD 1997年第3期188-190,共3页
According to the high thickness swelling and low dimensional stability of Poplars particleboard, this paper studied the effect of heat post-treatment on the board properties. The results indicated that the post-treatm... According to the high thickness swelling and low dimensional stability of Poplars particleboard, this paper studied the effect of heat post-treatment on the board properties. The results indicated that the post-treatment could be a very effective way to produce dimensinaly stable fast-growing poplars particleboard. The thickness swelling of the board decreased with increasing the time and temperatures of post-heat treatment. So under190℃, being treated for 15 min., the total thickness swelling (TS1) of the board was 8.96%, reduced by 22.88%. The irreversible thickness swelling (TS2) was also reduced with the post-treatment of 190 ℃ or 220℃; The reversible thickness swelling (TS3) was not signifcantly changed when the time of treatment increased up to 25 min. under 190℃. 展开更多
关键词 Heat post-treatment Thickness swelling PARTICLEBOARD
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Post-treatments of Super Absorbent Polymer
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作者 刘嵩 周翔 邢志奇 《Journal of Donghua University(English Edition)》 EI CAS 2002年第2期36-40,共5页
Properties of high absorbency and modulus (gel strength) were both needed in applications of superabsorbent polymer (SAP). Generally, the absorption characteristic and gel strength reach a crossover point for a given ... Properties of high absorbency and modulus (gel strength) were both needed in applications of superabsorbent polymer (SAP). Generally, the absorption characteristic and gel strength reach a crossover point for a given system. Beyond this point, a given property will show improvement at the expense of another property. To synthesize SAP with properties superior to this optimum value, further modification in the process becomes essential. In our post-treatment modification of superabsorbent polymer, neither the variety of the crosslinkers, nor their amount was found the effective factors to the polymer performance, but the liquor ratio of the treating liquid to polymer. The combination of the chemical treating and heat-treating method was also explored. But this didn’t put any positive effect on SAP’s properties. 展开更多
关键词 post-treatment SUPERABSORBENT POLYMER
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Method for determining the sliding-friction coefficient of the aluminum-zincplated post-treatment plate
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作者 ZHANG Xiaota FAN Chun 《Baosteel Technical Research》 CAS 2020年第1期44-48,共5页
With reference to the testing standard ASTM D1894,the sliding-friction coefficient of the aluminumzinc-plated post-treatment plate was measured.To reduce the detection error in practical applications,a correction fact... With reference to the testing standard ASTM D1894,the sliding-friction coefficient of the aluminumzinc-plated post-treatment plate was measured.To reduce the detection error in practical applications,a correction factor is proposed.Although the test results showed that the relative standard deviation of the friction coefficient of the aluminum-zinc-plated post-treatment plate was 12.1%indicating that the test results experienced a certain fluctuation,it can nevertheless be used as an internal factory-controlled test method.At the same time,problems were encountered with respect to sample contact,sample edge burr,and sample surface contamination.However,measures can be taken to reduce the impact of these factors. 展开更多
关键词 sliding-friction COEFFICIENT aluminum-zinc PLATE post-treatment PLATE
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Effects of microwave post-treatments on leaching resistance of ACQ-D treated Chinese fir
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作者 YU Li-li GAO Wei CAO Jin-zhen TANG Zhen-zhong 《Forestry Studies in China》 CAS 2010年第1期1-8,共8页
In order to improve the leaching resistance of active ingredient-copper in ammoniacal copper quat-type D (ACQ-D) treated Chinese fir (Cunninghamia lanceolata Hook.), microwave post-treatments were carried out. The... In order to improve the leaching resistance of active ingredient-copper in ammoniacal copper quat-type D (ACQ-D) treated Chinese fir (Cunninghamia lanceolata Hook.), microwave post-treatments were carried out. The percentages of leached copper from ACQ-D treated Chinese fir with different microwave post-treatments were obtained after leaching tests by analyzing the copper retention in treated wood. The fixation mechanism of copper in the treated wood was determined with the help of SEM and FTIR spectra, while the valence conversion of copper after microwave post-treatments was studied by UV spectroscopy. Our experimental results show that the percentage of leached copper was reduced significantly after microwave post-treatment over time. This development was reinforced by allowing even more time for the treatment as well as with an increase in the power of microwave post-treatment. The leaching resistance of copper in wrapped samples was better than that in unwrapped samples, which is attributed to the combined effects of temperature and moisture content. Compared with air-dried samples, the valence conversion in the samples with microwave post-treatments changed slightly, which demonstrates that microwave post-treatments cannot impair the natural decay resistance of ACQ-D treated wood. SEM and FTIR spectra showed the presence of crystal particles formed by chemical reactions between copper and wood ingredients in wood cell walls and wood pits. Only a small amount of copper reacted with cellulose, while lignin and hemicellulose were the major bonding sites for copper in wood. Given the experimental results of mechanical properties, microwave post-treatments had a slight effect on the compression strength parallel to the grain and on the erystallinity of ACQ-D treated Chinese fir. 展开更多
关键词 Chinese fir (Cunninghamia lanceolata Hook.) ammoniaeal copper quaternary ammonium salts type D (ACQ-D) COPPER leaching resistance microwave post-treatment
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老年早期胃癌患者内镜治疗术后伴发营养不良的风险预测模型构建
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作者 张军玲 黄娟娟 +2 位作者 姜素峰 卢晓云 张婷 《老年医学与保健》 CAS 2024年第4期947-952,共6页
目的 分析老年早期胃癌患者行内镜黏膜下剥离术(ESD)、内镜黏膜切除术(EMR)居家伴发营养不良的影响因素。方法 选取2022年1月-2023年12月在江苏省中医院接受早期胃癌行ESD或EMR治疗的80例老年患者作为研究对象,根据术后在居家环境中是... 目的 分析老年早期胃癌患者行内镜黏膜下剥离术(ESD)、内镜黏膜切除术(EMR)居家伴发营养不良的影响因素。方法 选取2022年1月-2023年12月在江苏省中医院接受早期胃癌行ESD或EMR治疗的80例老年患者作为研究对象,根据术后在居家环境中是否发生营养不良,将患者分为发生营养不良组(n=45)和未发生营养不良组(n=35)。采用单因素和多因素分析方法,探讨影响营养不良发生的高危因素。结果 单因素分析显示,2组高血压、血钾、血糖、血红蛋白检测值差异无统计学意义(P>0.05)。2组年龄、文化程度、焦虑得分、抑郁得分、早饱感、人格特质、术前低蛋白血症、术前血钙等均与胃癌患者术后发生营养不良有关(均P<0.05)。Logistic回归分析显示,年龄>75岁、抑郁得分>35分、有早饱感、焦虑得分≥29分、术前低蛋白血症等均为导致胃癌患者术后发生营养不良的独立危险因素(P<0.05)。以模型新生成概率值为依据,对该模型进行数据验证,绘制预测模型ROC曲线,可见AUC=0.862(95%CI:0.795~0.859)>0.75,最佳临界值为0.554,提示模型具有一定的预测能力。Hosmer-Lemeshow检验评价模型校准能力(χ^(2)=0.879,P=0.761>0.05),提示模型有良好的拟合优度。DCA结果显示,当营养不良临界概率值在9%~95%时,使用该模型能够获得较高的净收益。结论 本研究构建的老年早期胃癌患者术后营养不良风险预测模型,通过多因素Logistic回归分析发现,年龄>75岁、抑郁得分>35分、有早饱感、焦虑得分≥29分、术前低蛋白血症等可能为其独立危险因素。该模型经数据验证,具有较好的预测能力和校准度,且在营养不良临界概率值范围内显示出较高的净收益,可为临床实践中老年早期胃癌患者的术后营养管理提供参考。 展开更多
关键词 老年 胃癌 营养不良 影响因素 人格特质 低蛋白血症
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食管癌术后吻合口瘘的危险因素研究
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作者 赵云 崔健 《实用临床医药杂志》 CAS 2024年第1期37-40,共4页
目的探讨食管癌患者术后发生吻合口瘘的危险因素。方法回顾性分析107例食管癌手术患者的临床资料,将术后发生吻合口瘘的21例患者纳入观察组,将术后未发生吻合口瘘的86例患者纳入对照组,通过单因素分析和多因素Logistic回归分析明确食管... 目的探讨食管癌患者术后发生吻合口瘘的危险因素。方法回顾性分析107例食管癌手术患者的临床资料,将术后发生吻合口瘘的21例患者纳入观察组,将术后未发生吻合口瘘的86例患者纳入对照组,通过单因素分析和多因素Logistic回归分析明确食管癌术后发生吻合口瘘的危险因素。结果单因素分析结果显示,年龄、低蛋白血症、糖尿病史、术前新辅助治疗、吻合部位均与食管癌术后吻合口瘘有关(P<0.05);多因素Logistic回归分析显示,术前接受新辅助治疗是食管癌患者术后发生吻合口瘘的独立危险因素(OR=5.392,95%CI:1.335~30.382,P=0.020)。结论术前接受新辅助治疗是食管癌患者术后发生吻合口瘘的独立危险因素,对于术前合并其他系统疾病尤其是糖尿病、低蛋白血症的高危患者,应做好充分的术前准备。 展开更多
关键词 食管癌手术 吻合口瘘 新辅助治疗 低白蛋白血症 糖尿病 危险因素
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人体感染狒狒巴拉姆希阿米巴脑炎1例报告
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作者 李道佩 《中国人兽共患病学报》 CAS CSCD 北大核心 2024年第7期696-700,共5页
目的探讨狒狒巴拉姆希阿米巴脑炎的临床特点、诊断方法和治疗策略。方法回顾性分析病例资料。结果患者入院时检查异常的指标有:呼吸道病原体IgM阳性,华大基因测序结果检出狒狒巴拉姆希阿米巴的检出序列数为55,脑脊液分析结果显示白细胞... 目的探讨狒狒巴拉姆希阿米巴脑炎的临床特点、诊断方法和治疗策略。方法回顾性分析病例资料。结果患者入院时检查异常的指标有:呼吸道病原体IgM阳性,华大基因测序结果检出狒狒巴拉姆希阿米巴的检出序列数为55,脑脊液分析结果显示白细胞计数为371×10^(6)/L,蛋白定量为3321.4 mg/L,葡萄糖为2.33 mmol/L,氯化物为110 mmol/L,这些数据表明,患者存在严重感染症和免疫紊乱。经过6 d治疗,患者的病情虽有所好转,仍然危重。由于缺乏特效药物,预后极差,家属要求出院。结论狒狒巴拉姆希阿米巴脑炎是一种罕见但危险的疾病,临床表现多样,诊断难度较大,缺乏特效药物,治疗难度极大,预后极差。但对于疑似狒狒巴拉姆希阿米巴脑炎的患者,乃应早期进行综合性治疗,包括抗感染、免疫调节等治疗措施。 展开更多
关键词 狒狒巴拉姆阿米巴脑炎 基因测序 脑脊液 低蛋白血症 低钾血症 高钠血症
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持续非卧床腹膜透析患者低蛋白血症的影响因素分析
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作者 邓兆燕 李秋林 +2 位作者 甘剑光 李彦璇 杨雪群 《医药前沿》 2024年第27期32-35,共4页
目的:分析持续非卧床腹膜透析(CAPD)患者低蛋白血症的影响因素。方法:回顾性分析2018年1月—2022年12月玉林市第一人民医院收治的CAPD患者,按血清白蛋白水平分为低蛋白组(n=132)和正常蛋白组(n=215),比较两组临床资料,使用Logistic回归... 目的:分析持续非卧床腹膜透析(CAPD)患者低蛋白血症的影响因素。方法:回顾性分析2018年1月—2022年12月玉林市第一人民医院收治的CAPD患者,按血清白蛋白水平分为低蛋白组(n=132)和正常蛋白组(n=215),比较两组临床资料,使用Logistic回归分析模型分析低蛋白血症的危险因素。结果:低蛋白组的血清白蛋白、左室射血分数、白细胞、血红蛋白、球蛋白、前白蛋白、总胆固醇、甘油三酯和血钙水平低于正常蛋白组,24 h腹透液蛋白浓度、24 h腹透液蛋白总量高于正常蛋白组,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,左室射血分数、血红蛋白、前白蛋白和甘油三酯下降是CAPD患者低蛋白血症的影响因素(P<0.05)。结论:CAPD患者低蛋白血症发生率较高。左室射血分数、血红蛋白、前白蛋白和甘油三酯下降是CAPD患者低蛋白血症的影响因素。积极预防和治疗心力衰竭与心肌重构,纠正贫血,进行营养评估和干预,以预防低蛋白血症的发生。 展开更多
关键词 持续非卧床腹膜透析 低蛋白血症 影响因素
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四肢创伤骨折病人术后低蛋白血症的危险因素分析及风险预测模型的构建 被引量:1
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作者 朱爱朝 魏建军 +2 位作者 周俊 方五洲 程恺 《安徽医药》 CAS 2024年第2期376-380,共5页
目的 探讨四肢创伤骨折病人术后低蛋白血症的危险因素,并构建四肢创伤骨折病人术后低蛋白血症的风险预测模型。方法 选取2018年3月至2022年8月池州市人民医院手术治疗的226例四肢创伤骨折病人作为研究对象。应用Lasso分析筛选四肢创伤... 目的 探讨四肢创伤骨折病人术后低蛋白血症的危险因素,并构建四肢创伤骨折病人术后低蛋白血症的风险预测模型。方法 选取2018年3月至2022年8月池州市人民医院手术治疗的226例四肢创伤骨折病人作为研究对象。应用Lasso分析筛选四肢创伤骨折病人术后低蛋白血症的预测因素,应用logistic回归分析筛选四肢创伤骨折病人术后低蛋白血症的危险因素,应用R软件构建四肢创伤骨折病人术后低蛋白血症的列线图模型,并对四肢创伤骨折病人术后低蛋白血症的列线图模型进行验证。结果 logistic回归分析结果显示,女性、年龄≥65岁、术中出血量≥300 mL、胃肠功能损伤、肺部感染、术前白蛋白<35 g/L、衰弱、输注胶体液及蛋白等是四肢创伤骨折病人术后低蛋白血症的危险因素(P<0.05)。四肢创伤骨折病人术后低蛋白血症的列线图模型的校正曲线显示预测值与实际值的拟合度较好;模型的AUC是0.84[95%CI:(0.80,0.87)];决策曲线显示阈值概率在2%~75%范围内时,应用该列线图预测四肢创伤骨折病人术后低蛋白血症净获益值较高。结论 女性、年龄≥65岁、术中出血量≥300 mL、胃肠功能损伤、肺部感染、术前白蛋白<35 g/L、衰弱、输注胶体液及蛋白等是四肢创伤骨折病人术后低蛋白血症的危险因素,本研究基于以上8项危险因素构建的列线图能够对四肢创伤骨折病人术后低蛋白血症的防治工作起到帮助作用。 展开更多
关键词 骨折 四肢 骨折固定术 低蛋白血症 危险因素 列线图
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胃肠道肿瘤患者术后低蛋白血症的相关危险因素分析和预测模型建立
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作者 李壮 王珊珊 +4 位作者 丁丽蓉 苏珍 刘海林 陶国全 张志捷 《现代肿瘤医学》 CAS 2024年第14期2579-2585,共7页
目的:旨在筛选胃肠道肿瘤术后低蛋白血症的围术期相关危险因素,并建立相应预测模型。方法:回顾性分析2022年12月至2023年6月在我院行胃肠道肿瘤根治术的244例患者临床资料,运用Logistic回归分析对术后低蛋白血症的相关因素进行单因素和... 目的:旨在筛选胃肠道肿瘤术后低蛋白血症的围术期相关危险因素,并建立相应预测模型。方法:回顾性分析2022年12月至2023年6月在我院行胃肠道肿瘤根治术的244例患者临床资料,运用Logistic回归分析对术后低蛋白血症的相关因素进行单因素和多因素分析,筛选出独立危险因素;并建立Nomogram预测模型,评估其预测价值。结果:研究结果显示,共计125例患者术后出现低蛋白血症,占比54.8%。多因素Logistic回归分析显示:术前白蛋白水平(OR 0.70,P<0.01)、BMI(OR 0.79,P<0.01),术中激素(OR 0.92,P<0.01)、白蛋白使用量(OR 0.72,P<0.01),术毕血糖(OR 1.54,P<0.01)和复合硬膜外麻醉(OR 0.38,P<0.05)为术后低蛋白血症发生的独立危险因素。预测模型ROC曲线下面积为0.848(95%CI 0.800~0.896),预测价值较好。结论:术前白蛋白水平、BMI,术中激素、术中白蛋白使用量,术毕血糖和复合硬膜外麻醉是术后低蛋白血症发生的独立危险因素,基于上述变量的Nomogram列线图预测模型具有较高的预测效能,可为临床决策提供有效参考。 展开更多
关键词 胃肠道肿瘤 低蛋白血症 手术后并发症 危险因素 列线图
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应用托伐普坦治疗糖尿病肾病综合征所致顽固性水肿个案分析
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作者 刘睿茜 杨阳 高金祥 《国际医药卫生导报》 2024年第7期1172-1176,共5页
糖尿病肾病综合征(diabeticnephropathysyndrome,DNS)是一种非免疫因素介导的继发性肾病综合征。由于其发病为非免疫因素介导,此类患者应用激素治疗无效,导致其引起的水肿在治疗上更加依赖利尿剂。新型利尿剂托伐普坦是一种选择性血管... 糖尿病肾病综合征(diabeticnephropathysyndrome,DNS)是一种非免疫因素介导的继发性肾病综合征。由于其发病为非免疫因素介导,此类患者应用激素治疗无效,导致其引起的水肿在治疗上更加依赖利尿剂。新型利尿剂托伐普坦是一种选择性血管加压素V2受体拮抗剂,其发挥作用不依赖于白蛋白,目前主要用于减轻肝硬化、心力衰竭、抗利尿激素分泌异常综合征等导致的水肿,还可用于常染色体显性多囊肾病的辅助治疗,但在DNS患者中的应用较少。本文通过分享应用托伐普坦治疗1例顽固性水肿的DNS患者的经过,探讨托伐普坦治疗DNS患者的效果、安全性及未来前景。 展开更多
关键词 糖尿病肾病综合征 托伐普坦 水肿 低蛋白血症
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重度子痫前期并发心功能不全的危险因素分析
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作者 吴秀秀 胡文胜 +1 位作者 沈旭娜 占思思 《中国现代医生》 2024年第6期63-66,共4页
目的探究重度子痫前期(severe preeclampsia,sPE)出现心功能不全相关的危险因素。方法选取2020年1月至2023年9月于温州市中心医院住院的sPE并发心功能不全的患者32例作为实验组,并随机选取同时期心功能正常的sPE患者75例作为对照组。比... 目的探究重度子痫前期(severe preeclampsia,sPE)出现心功能不全相关的危险因素。方法选取2020年1月至2023年9月于温州市中心医院住院的sPE并发心功能不全的患者32例作为实验组,并随机选取同时期心功能正常的sPE患者75例作为对照组。比较两组患者的一般资料和实验室指标的差异,采用二元Logistic回归分析探讨sPE出现心功能不全的危险因素。结果实验组患者出现呼吸衰竭、血管内溶血-肝酶升高-低血小板、感染的例数高于对照组,差异有统计学意义(P<0.05)。对照组发生新生儿窒息、新生儿转重症监护的例数高于实验组,差异有统计学意义(P<0.05)。两组患者的孕前体质量指数、孕期体质量增幅、血钙、白蛋白、血红蛋白、双胎、感染差异有统计学意义(P<0.05),二元Logistic回顾分析结果显示,孕前体质量指数增加、孕期体质量增幅≥20kg、低血钙、低白蛋白、中度贫血、孕期血压增加是sPE出现心功能不全的危险因素。结论孕期应积极控制血压、补钙、补铁、补充白蛋白、控制体质量;对sPE患者增加血钙、白蛋白、血红蛋白、血压相关指标监测的频率,积极控制血压、解痉、预防感染可减少sPE患者心功能不全的发生。 展开更多
关键词 重度子痫前期 心功能不全 低钙血症 低蛋白血症 贫血
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冠状动脉旁路移植术后低清蛋白血症危险因素与预后
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作者 赵冬 张雪娟 路长鸿 《青岛大学学报(医学版)》 CAS 2024年第1期100-104,共5页
目的探讨冠状动脉旁路移植术(CABG)后低清蛋白血症的危险因素及临床预后。方法回顾分析CABG病人483例,定义术后第1天血清清蛋白(ALB)水平较术前下降的差值为△ALB,将△ALB≤7 g/L病人97例归为A组、7 g/L<△ALB≤15 g/L病人298例归为... 目的探讨冠状动脉旁路移植术(CABG)后低清蛋白血症的危险因素及临床预后。方法回顾分析CABG病人483例,定义术后第1天血清清蛋白(ALB)水平较术前下降的差值为△ALB,将△ALB≤7 g/L病人97例归为A组、7 g/L<△ALB≤15 g/L病人298例归为B组、△ALB>15 g/L病人88例归为C组。比较3组病人术前、术中、术后相关资料及术后随访36个月主要不良心血管事件(MACE)发生情况。结果C组合并高尿酸血症的病人数及左室射血分数<40%的病人数高于A、B两组,差异有统计学意义(χ^(2)=6.802~6.857,P<0.05);B、C两组中有介入治疗(PCI)史的病人数高于A组,差异有统计学意义(χ^(2)=8.193,P<0.05);C组术后在ICU停留时间>72 h、CABG当天引流>400 mL、大量失血、输注红细胞、输注血浆、肾损伤等病人占比明显高于A、B两组,差异有统计学意义(χ^(2)=6.741~39.287,P<0.05);C组术后MACE事件发生率高于A、B两组,差异有统计学意义(χ^(2)=8.205,P<0.05)。Cox回归分析中校正多种混杂因素后,病人术前有PCI史(OR=1.670,95%CI=1.091~2.556,P=0.018)及左室射血分数<40%(OR=4.468,95%CI=2.304~8.665,P<0.001)是术后ALB水平减低的独立危险因素,CABG后第1天ALB水平较术前下降程度7 g/L<△ALB≤15 g/L(OR=2.784,95%CI=1.190~6.516,P=0.018)和△ALB>15 g/L(OR=3.487,95%CI=1.373~8.853,P=0.009)是远期MACE的独立预测因素。结论PCI史及左室射血分数<40%是CABG后ALB水平减低的独立危险因素,术后第1天ALB水平较术前下降>7 g/L是CABG预后的预测因素。 展开更多
关键词 低白蛋白血症 冠状动脉分流术 危险因素 预后
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腹腔镜结直肠癌根治术后动力性肠梗阻发生情况及高危因素分析 被引量:1
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作者 张梦娇 《罕少疾病杂志》 2024年第3期80-81,84,共3页
目的探讨结直肠癌患者腹腔镜下根治术后动力性肠梗阻发生现状及影响因素。方法选取2020年2月-2023年4月我院收治的80例腹腔镜下结直肠癌根治术患者,根据术后是否发生动力性肠梗阻分为两组。收集患者性别、年龄、体重指数、文化程度、肿... 目的探讨结直肠癌患者腹腔镜下根治术后动力性肠梗阻发生现状及影响因素。方法选取2020年2月-2023年4月我院收治的80例腹腔镜下结直肠癌根治术患者,根据术后是否发生动力性肠梗阻分为两组。收集患者性别、年龄、体重指数、文化程度、肿瘤位置、TNM分期、分化程度、术前是否有肠梗阻、腹部手术史、合并贫血、淋巴结转移、低蛋白血症、肿瘤直径、手术时间、吸烟酗酒史等资料。对一般资料进行单因素分析,再对有统计学差异因素的进行多因素Logistic回归分析。结果80例腹腔镜下结直肠癌根治术患者,18例动力性肠梗阻,发生率22.50%;单因素分析显示,两组TNM分期、术前是否有肠梗阻、腹部手术史、术前是否合并贫血、是否淋巴结转移、术前是否有低蛋白血症比较,差异有统计学意义(χ^(2)=18.148、7.681、8.119、10.904、9.395,P=0.000、0.003、0.006、0.0.05、0.001);Logistic回归分析TNM分期为Ⅲ期、术前有肠梗阻、有腹部手术史等是影响腹腔镜下结直肠癌根治术后动力性肠梗阻发生的独立危险因素(P<0.05且OR>1)。结论直肠癌患者腹腔镜根治术后动力性肠梗阻发生与TNM分期为Ⅲ期、术前有肠梗阻等有关,及时制定针对性预防措施,从而减少动力性肠梗阻。 展开更多
关键词 结直肠癌 动力性肠梗阻 高危因素 低蛋白血症
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