With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Techn...With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Technology”serves as the foundation for cultivating students’abilities in cosmetic development and preparation.To foster high-quality skilled talents capable of adapting to the rapid growth of color cosmetics and to better promote the deep integration of scientific and technological industries with curriculum teaching,the teacher team embarked on active explorations and practical teaching research for curriculum teaching reform from four dimensions:strengthening top-level design,enriching teaching content,optimizing teaching design,and reforming assessment methods.These efforts have enhanced students’comprehensive vocational qualities and innovative consciousness,contributing to the teaching reform in higher vocational colleges under the integration of industry,education,and research.展开更多
[Objectives]To optimize the extraction and preparation technology of Wuwei Xiaoke granules.[Methods]Taking the extraction rate of extract as the scoring standard,the water extraction technology was optimized by orthog...[Objectives]To optimize the extraction and preparation technology of Wuwei Xiaoke granules.[Methods]Taking the extraction rate of extract as the scoring standard,the water extraction technology was optimized by orthogonal test.The influence of the proportion of pharmaceutical excipients on the molding conditions of Wuwei Xiaoke granules was investigated using granule molding rate,solubility,moisture,granularity,water-soluble extract and microorganism examination as evaluation indicators,and the optimal molding technology was optimized.[Results]The extraction technology was soaking in water for 0.5 h and heat extraction twice for 1 h each time:adding 10 times the amount of water in the first time,and adding 8 times the amount of water in the second time.The best molding technology was:extract density 1.13-1.16(55-60℃),extract:soluble starch=1:2,and 0.15%stevioside.[Conclusions]The water extraction technology and granule molding technology optimized by orthogonal test are reliable and stable,with good granular characteristics,easy oral administration and good solubility,which can maximize the comprehensive quality of Wuwei Xiaoke granules,and provide an effective reference for the preparation and production of Wuwei Xiaoke granules.展开更多
Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier fo...Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier for the inheritance and innovation of traditional Chinese medicine.In recent years,the research and development of traditional Chinese medicine preparations has become a hot spot in the research and development of preparations by medical institutions.Traditional Chinese medicine preparations prepared by traditional processes and their entrusted preparation matters have changed from the current licensing management to filing management.The registration model of traditional Chinese medicine preparations has undergone significant changes,emphasizing more on real data and evaluation results from the objective world,respecting traditional medication experience,and emphasizing the inheritance and innovative development of traditional technological experience.In the process of following teachers in the inheritance project of traditional Chinese medicine,we combined the inheritance of traditional Chinese medicine characteristic technology with the research and development practice of traditional Chinese medicine preparations in medical institutions,and focused on the analysis and discussion of technical problems such as prescription screening,dosage form selection,process route design and clinical observation of traditional Chinese medicine preparations,hoping to provide reference for scholars in the same field of traditional Chinese medicine.展开更多
Cu-Zn-Al slurry catalysts were prepared using a complete liquid-phase preparation technology under different heat treatment atmospheres.The catalysts were characterized using X-ray diffraction,X-ray photoelectron spec...Cu-Zn-Al slurry catalysts were prepared using a complete liquid-phase preparation technology under different heat treatment atmospheres.The catalysts were characterized using X-ray diffraction,X-ray photoelectron spectroscope,and N2 adsorption-desorption.Their application in the single-step synthesis of dimethyl ether from syngas was also investigated.The results indicate that the type of heat treatment atmosphere has an influence on the Cu species and the Cu0/Cu+ ratio on the catalyst surface.Moreover,the final Cu/Zn ratio on the catalyst surface is mainly dependent on the composition and reaction environment of the catalyst and less on the type of heat treatment atmosphere.The prepared catalysts can suppress sintering of active sites at high temperatures,and the type of heat treatment atmosphere mainly affects the capability of the catalyst for methanol synthesis.The catalysts perform best using N2 as the heat treatment atmosphere.展开更多
Coated capillary columns were prepared by sol-gel technology and used in the separation of basic proteins with capillary zone electrophoresis. The results indicated that a significant decrease in protein adsorption wa...Coated capillary columns were prepared by sol-gel technology and used in the separation of basic proteins with capillary zone electrophoresis. The results indicated that a significant decrease in protein adsorption was obtained and EOF was also diminished to zero in the pH range of 3-10.展开更多
The inception of radioisotope and its application in China are introduced. The research,development, production, application progress and the future development prospect of radioisotope and its products are described.
[Objectives] The aim was to explore the best parameters for processing Aconiti Kusnezoffii Radix by bean curd. [Methods] Orthogonal test( L_(16)(4~3)) was designed to investigate the optimal soaking time,decocting tim...[Objectives] The aim was to explore the best parameters for processing Aconiti Kusnezoffii Radix by bean curd. [Methods] Orthogonal test( L_(16)(4~3)) was designed to investigate the optimal soaking time,decocting time and bean curd proportion for processing Aconiti Kusnezoffii Radix by bean curd. The contents of monoester alkaloids and diester-alkaloids were measured as the evaluation indexes. [Results]The contents of monoester alkaloids were 0. 11%,0. 07%,0. 062% and 0. 048% respectively under the four levels of soaking time,were0. 081%,0. 066%,0. 074% and 0. 067% respectively under the four levels of decocting time,and were 0. 070%,0. 072%,0. 080% and0. 073% respectively under the four levels of bean curd proportion. The content of diester-alkaloids was all below 0. 034%. The influence intensity of the three factors on the content of monoester alkaloids ranked as soaking time > decocting time > bean curd proportion. Under any of the above conditions,the content of diester-alkaloids was below the limit of Chinese Pharmacopoeia. The content of diester-alkaloids was reduced obviously with the increased use of bean curd. [Conclusions] The optimum processing conditions for Aconiti Kusnezoffii Radix were A_3B_3C_2,i. e.,soaking time of 6 d,decocting time of 5 h and bean curd proportion of 25%.展开更多
[Objectives] To explore the optimal process for preparing hydroxypropyl tetrahydropyrantriol liposomes. [Methods] A refractive index method was used to determine the content of hydroxypropyl tetrahydropyrantriol. Usin...[Objectives] To explore the optimal process for preparing hydroxypropyl tetrahydropyrantriol liposomes. [Methods] A refractive index method was used to determine the content of hydroxypropyl tetrahydropyrantriol. Using particle size distribution and encapsulation rate as evaluation indicators, the effects of hydration time, ratio of organic phase to aqueous phase, granulation method, as well as thin film dispersion and reverse evaporation methods on liposomes preparation were investigated, and the optimal preparation method was selected. Single factor experiments were used to screen the drug phospholipid ratio, ultrasound time, and phospholipid cholesterol ratio, and the preparation process was optimized through orthogonal experiments. [Results] The optimal process of preparing hydroxypropyl tetrahydropyrantriol liposomes was as below: 1 : 10 of drug phospholipid ratio, 6 min of ultrasound time, 4 : 1 of phospholipid cholesterol ratio, (60.94%±7.24%) of entrapment efficiency, (86.44±6.08) nm of particle size, (0.195±0.077) of PDI. [Conclusions] The optimal preparation process of hydroxypropyl tetrahydropyrantriol liposomes selected by orthogonal experiment could effectively improve the encapsulation efficiency of hydroxypropyl tetrahydropyranotriol and reduce particle size. Moreover, the method was stable and reliable.展开更多
In this work, the costs for machinery and all means for site preparation of forest clearings for afforestation with intensivepoplar plantations were studied by applying various technological schemes. For this purpose,...In this work, the costs for machinery and all means for site preparation of forest clearings for afforestation with intensivepoplar plantations were studied by applying various technological schemes. For this purpose, three technological schemes (TS1,TS2and TS3), applying in Bulgaria, were studied. By applying the respective technological scheme, the site preparation was performedentirely with a milling aggregate PT-400, equipped with multifunctional forest tiller FAE-300/S. The processes of shredding stumps,mulching clearing debris and bushes, and primary tillage of the soil up to depth of 50 cm were examined. The survey was conductedin poplar clearings along the river Danube, over alluvial moderately moist soil. A new categorization of the poplar clearings isproposed depending on the operating conditions. The performance of the milling unit and the relative costs for labor, machinery andmeans for site preparation per unit area were defined. Depending on the category of poplar clearings, total cost for site preparationapplying the studied technology vary between 27.6 h/ha and 29.3 h/ha, which at current prices of 53.5 ∈/h for the operation of PT-400with FAE 300/S is between ∈1,478/ha and ∈1,569/ha. To conduct comparative analysis of the new technology and the oldtechnologies under similar operating conditions, the relatively costs for site preparation of the previously applied technologies whichuse rotary and tooth uprooter machines are defmed. According to the applied technological scheme and used machines in differentcategories, clearings costs for land preparation vary between ∈1,230/ha and ∈3,300/ha. Based on comparative analysis, it is designeda new technological scheme for afforestation with poplar plantations in riverside clearings, where by ensuring high quality work, thecosts for site preparation become lower (24.2-25.9 h/ha) and thus cost from ∈993/ha to 61,084/ha is achieved.展开更多
文摘With the upgrading of industries,the cosmetics industry has posed new requirements for technical talents.As a professional core course in cosmetic technology,“Cosmetic Product Formulation Design and Preparation Technology”serves as the foundation for cultivating students’abilities in cosmetic development and preparation.To foster high-quality skilled talents capable of adapting to the rapid growth of color cosmetics and to better promote the deep integration of scientific and technological industries with curriculum teaching,the teacher team embarked on active explorations and practical teaching research for curriculum teaching reform from four dimensions:strengthening top-level design,enriching teaching content,optimizing teaching design,and reforming assessment methods.These efforts have enhanced students’comprehensive vocational qualities and innovative consciousness,contributing to the teaching reform in higher vocational colleges under the integration of industry,education,and research.
基金Supported by Self-funded Research Project of Traditional Chinese Medicine Administration of Guangxi Zhuang Autonomous Region(GXZYZ20210313)National TCM Characteristic Technology Inheritance Talent Training Program(GZYYBRJF[2014]39).
文摘[Objectives]To optimize the extraction and preparation technology of Wuwei Xiaoke granules.[Methods]Taking the extraction rate of extract as the scoring standard,the water extraction technology was optimized by orthogonal test.The influence of the proportion of pharmaceutical excipients on the molding conditions of Wuwei Xiaoke granules was investigated using granule molding rate,solubility,moisture,granularity,water-soluble extract and microorganism examination as evaluation indicators,and the optimal molding technology was optimized.[Results]The extraction technology was soaking in water for 0.5 h and heat extraction twice for 1 h each time:adding 10 times the amount of water in the first time,and adding 8 times the amount of water in the second time.The best molding technology was:extract density 1.13-1.16(55-60℃),extract:soluble starch=1:2,and 0.15%stevioside.[Conclusions]The water extraction technology and granule molding technology optimized by orthogonal test are reliable and stable,with good granular characteristics,easy oral administration and good solubility,which can maximize the comprehensive quality of Wuwei Xiaoke granules,and provide an effective reference for the preparation and production of Wuwei Xiaoke granules.
基金Supported by The Third Batch of Traditional Chinese Medicine Famous Doctors Inheritance Implementation Project in Guizhou Province in 2021(QZYYH[2021]106).
文摘Medical institution preparations play an important role in the development of hospitals,being one of the main forms of traditional Chinese medicine clinical characteristic medication,as well as an important carrier for the inheritance and innovation of traditional Chinese medicine.In recent years,the research and development of traditional Chinese medicine preparations has become a hot spot in the research and development of preparations by medical institutions.Traditional Chinese medicine preparations prepared by traditional processes and their entrusted preparation matters have changed from the current licensing management to filing management.The registration model of traditional Chinese medicine preparations has undergone significant changes,emphasizing more on real data and evaluation results from the objective world,respecting traditional medication experience,and emphasizing the inheritance and innovative development of traditional technological experience.In the process of following teachers in the inheritance project of traditional Chinese medicine,we combined the inheritance of traditional Chinese medicine characteristic technology with the research and development practice of traditional Chinese medicine preparations in medical institutions,and focused on the analysis and discussion of technical problems such as prescription screening,dosage form selection,process route design and clinical observation of traditional Chinese medicine preparations,hoping to provide reference for scholars in the same field of traditional Chinese medicine.
基金supported by the National Natural Science Foundation of China(No.20706039)the National Basic Research Program(973 Program) of China (No.2005CB221204)+1 种基金the Program for the Top Young Academic Leaders of Higher Learning Institutions of Shanxi of China in 2010the Young Scientific and the Technical Fund of Shanxi of China (No.2006021010)
文摘Cu-Zn-Al slurry catalysts were prepared using a complete liquid-phase preparation technology under different heat treatment atmospheres.The catalysts were characterized using X-ray diffraction,X-ray photoelectron spectroscope,and N2 adsorption-desorption.Their application in the single-step synthesis of dimethyl ether from syngas was also investigated.The results indicate that the type of heat treatment atmosphere has an influence on the Cu species and the Cu0/Cu+ ratio on the catalyst surface.Moreover,the final Cu/Zn ratio on the catalyst surface is mainly dependent on the composition and reaction environment of the catalyst and less on the type of heat treatment atmosphere.The prepared catalysts can suppress sintering of active sites at high temperatures,and the type of heat treatment atmosphere mainly affects the capability of the catalyst for methanol synthesis.The catalysts perform best using N2 as the heat treatment atmosphere.
文摘Coated capillary columns were prepared by sol-gel technology and used in the separation of basic proteins with capillary zone electrophoresis. The results indicated that a significant decrease in protein adsorption was obtained and EOF was also diminished to zero in the pH range of 3-10.
文摘The inception of radioisotope and its application in China are introduced. The research,development, production, application progress and the future development prospect of radioisotope and its products are described.
文摘[Objectives] The aim was to explore the best parameters for processing Aconiti Kusnezoffii Radix by bean curd. [Methods] Orthogonal test( L_(16)(4~3)) was designed to investigate the optimal soaking time,decocting time and bean curd proportion for processing Aconiti Kusnezoffii Radix by bean curd. The contents of monoester alkaloids and diester-alkaloids were measured as the evaluation indexes. [Results]The contents of monoester alkaloids were 0. 11%,0. 07%,0. 062% and 0. 048% respectively under the four levels of soaking time,were0. 081%,0. 066%,0. 074% and 0. 067% respectively under the four levels of decocting time,and were 0. 070%,0. 072%,0. 080% and0. 073% respectively under the four levels of bean curd proportion. The content of diester-alkaloids was all below 0. 034%. The influence intensity of the three factors on the content of monoester alkaloids ranked as soaking time > decocting time > bean curd proportion. Under any of the above conditions,the content of diester-alkaloids was below the limit of Chinese Pharmacopoeia. The content of diester-alkaloids was reduced obviously with the increased use of bean curd. [Conclusions] The optimum processing conditions for Aconiti Kusnezoffii Radix were A_3B_3C_2,i. e.,soaking time of 6 d,decocting time of 5 h and bean curd proportion of 25%.
基金Supported by Innovation and Entrepreneurship Training Program Project of Southwest Minzu University(S202210656134)Project of Sichuan Department of Science and Technology(2022NSFSC1437)Project of Sichuan Administration of Traditional Chinese Medicine(2021MS121).
文摘[Objectives] To explore the optimal process for preparing hydroxypropyl tetrahydropyrantriol liposomes. [Methods] A refractive index method was used to determine the content of hydroxypropyl tetrahydropyrantriol. Using particle size distribution and encapsulation rate as evaluation indicators, the effects of hydration time, ratio of organic phase to aqueous phase, granulation method, as well as thin film dispersion and reverse evaporation methods on liposomes preparation were investigated, and the optimal preparation method was selected. Single factor experiments were used to screen the drug phospholipid ratio, ultrasound time, and phospholipid cholesterol ratio, and the preparation process was optimized through orthogonal experiments. [Results] The optimal process of preparing hydroxypropyl tetrahydropyrantriol liposomes was as below: 1 : 10 of drug phospholipid ratio, 6 min of ultrasound time, 4 : 1 of phospholipid cholesterol ratio, (60.94%±7.24%) of entrapment efficiency, (86.44±6.08) nm of particle size, (0.195±0.077) of PDI. [Conclusions] The optimal preparation process of hydroxypropyl tetrahydropyrantriol liposomes selected by orthogonal experiment could effectively improve the encapsulation efficiency of hydroxypropyl tetrahydropyranotriol and reduce particle size. Moreover, the method was stable and reliable.
文摘In this work, the costs for machinery and all means for site preparation of forest clearings for afforestation with intensivepoplar plantations were studied by applying various technological schemes. For this purpose, three technological schemes (TS1,TS2and TS3), applying in Bulgaria, were studied. By applying the respective technological scheme, the site preparation was performedentirely with a milling aggregate PT-400, equipped with multifunctional forest tiller FAE-300/S. The processes of shredding stumps,mulching clearing debris and bushes, and primary tillage of the soil up to depth of 50 cm were examined. The survey was conductedin poplar clearings along the river Danube, over alluvial moderately moist soil. A new categorization of the poplar clearings isproposed depending on the operating conditions. The performance of the milling unit and the relative costs for labor, machinery andmeans for site preparation per unit area were defined. Depending on the category of poplar clearings, total cost for site preparationapplying the studied technology vary between 27.6 h/ha and 29.3 h/ha, which at current prices of 53.5 ∈/h for the operation of PT-400with FAE 300/S is between ∈1,478/ha and ∈1,569/ha. To conduct comparative analysis of the new technology and the oldtechnologies under similar operating conditions, the relatively costs for site preparation of the previously applied technologies whichuse rotary and tooth uprooter machines are defmed. According to the applied technological scheme and used machines in differentcategories, clearings costs for land preparation vary between ∈1,230/ha and ∈3,300/ha. Based on comparative analysis, it is designeda new technological scheme for afforestation with poplar plantations in riverside clearings, where by ensuring high quality work, thecosts for site preparation become lower (24.2-25.9 h/ha) and thus cost from ∈993/ha to 61,084/ha is achieved.