Hardening Effect on Machined Surface for Precise Hard Cutting Process with Consideration of Tool Wear

During hard cutting process there is severe thermodynamic coupling effect between cutting tool and workpiece, which causes quenching effect on finished surfaces under certain conditions. However, material phase transformation mechanism of heat treatment in cutting process is different from the one in traditional process, which leads to changes of the formation mechanism of damaged layer on machined workpiece surface. This paper researches on the generation mechanism of damaged layer on machined surface in the process of PCBN tool hard cutting hardened steel Cr12MoV. Rules of temperature change on machined surface and subsurface are got by means of finite element simulation. In phase transformation temperature experiments rapid transformation instrument is employed, and the effect of quenching under cutting conditions on generation of damaged layer is revealed. Based on that, the phase transformation points of temperature under cutting conditions are determined. By experiment, the effects of cutting speed and tool wear on white layer thickness in damaged layer are revealed. The temperature distribution law of third deformation zone is got by establishing the numerical prediction model, and thickness of white layer in damaged layer is predicted, taking the tool wear effect into consideration. The experimental results show that the model prediction is accurate, and the establishment of prediction model provides a reference for wise selection of parameters in precise hard cutting process. For the machining process with high demanding on surface integrity, the generation of damaged layer on machined surface can be controlled precisely by using the prediction model.

Alcohol metabolites and lipopolysaccharide: Roles in the development and/or progression of alcoholic liver disease

The onset of alcoholic liver disease (ALD) is initiated by different cell types in the liver and a number of different factors including: products derived from ethanol-induced inflammation, ethanol metabolites, and the indirect reactions from those metabolites. Ethanol oxidation results in the production of metabolites that have been shown to bind and form protein adducts, and to increase inflammatory, fibrotic and cirrhotic responses. Lipopolysaccharide (LPS) has many deleterious effects and plays a significant role in a number of disease processes by increasing inflammatory cytokine release. In ALD, LPS is thought to be derived from a breakdown in the intestinal wall enabling LPS from resident gut bacterial cell walls to leak into the blood stream. The ability of adducts and LPS to independently stimulate the various cells of the liver provides for a two-hit mechanism by which various biological responses are induced and result in liver injury. Therefore, the purpose of this article is to evaluate the effects of a two-hit combination of ethanol metabolites and LPS on the cells of the liver to increase inflamma-tion and fi brosis, and play a role in the development and/or progression of ALD.

Development of Integrated Precision Vibration-Assisted Micro-Engraving System

A novel precision vibration-assisted micro-engraving system was developed by the integration of fast tool servo and ultrasonic elliptical vibration system, in which the flexure hinge was designed to avoid backlash and PID control algorithm was established to guarantee specific precision. Apart from experimental validation of the performance of the system, various micro-V-grooves cutting experiments on aluminum alloy, ferrous material and hard cutting material were performed, in which Kistler force sensor was used to measure cutting force. Through experiments, it was clear that the vibration-assisted micro-engraving system can ensure good quality of micro-V-grooves and reduce cutting force by about 60% compared with traditional removal process without ultrasonic vibration.

Adaptive compensation of sculptured surface machining errors by open architecture manufacturing system

Presents the adaptive compensation of sculptured surface machining errors by using the open architecture intelligent manufacturing system to ensure real time high precision machining of sculptured surface, and the tool deflection model constructed for prediction of machining errors to be compensated and analysis of the effect of tool deflection on machining errors, and concludes from experimental results that the open architecture intelligent manufacturing system can effectively improve the machining precision and reduce the machining errors by 30%.

Hybrid multibody system method for the dynamic analysis of an ultra‐precision fly‐cutting machine tool

The dynamics of an ultra‐precision machine tool determines the precision of the machined surface.This study aims to propose an effective method to model and analyze the dynamics of an ultra‐precision fly‐cutting machine tool.First,the dynamic model of the machine tool considering the deformations of the cutter head and the lathe head is developed.Then,the mechanical elements are classified into M subsystems and F subsystems according to their properties and connections.The M‐subsystem equations are formulated using the transfer matrix method for multibody systems(MSTMM),and the F‐subsystem equations are analyzed using the finite element method and the Craig-Bampton reduction method.Furthermore,all the subsystems are assembled by combining the restriction equations at connection points among the subsystems to obtain the overall transfer equation of the machine tool system.Finally,the vibration characteristics of the machine tool are evaluated numerically and are validated experimentally.The proposed modeling and analysis method preserves the advantages of the MSTMM,such as high computational efficiency,low computational load,systematic reduction of the overall transfer equation,and generalization of its computational capability to general flexible‐body elements.In addition,this study provides theoretical insights and guidance for the design of ultra‐precision machine tools.