The performance of the designed digital electro-pneumatic cabin pressure control system for the cabin pressure schedule of transport aircraft is investigated.For the purpose of this study,an experimental setup consist...The performance of the designed digital electro-pneumatic cabin pressure control system for the cabin pressure schedule of transport aircraft is investigated.For the purpose of this study,an experimental setup consisting of a simulated hermetic cabin and altitude simulation chamber is configured for cabin pressure control system operation.A series of experimental tests are executed to evaluate the performance of the cabin pressure control system.The parameters of the PID controller are optimized.In the optimization process,the variation regularity of the rate of cabin pressure change under various conditions is considered.An approach to prioritize the control of the rate of change of cabin pressure based on the flight status model is proposed and verified experimentally.The experimental results indicate that the proposed approach can be adopted for the designed digital electro-pneumatic cabin pressure control system to obtain a better cabin pressure schedule and rate of cabin pressure change.展开更多
Objective: The association hypertension and diabetes is important. The two pathologies may influence each other. The aim was to study the correlation between glycemic control and blood pressure control and to determin...Objective: The association hypertension and diabetes is important. The two pathologies may influence each other. The aim was to study the correlation between glycemic control and blood pressure control and to determine the factors associated with blood pressure control. Methodology: This was a descriptive cross-sectional study with an analytical focus over 7 months. Patients were recruited as outpatients and all underwent ambulatory blood pressure measure, glycated hemoglobin and creatinine measurements, and assessment of compliance with treatment. Results: During this period 116 patients were collected. The predominance was female 69%. The mean age of the patients was 62 ± 7 years with a peak between 60 and 70 years. The average age of hypertension was 12 years and that of diabetes 6 1/2 years. The most frequently associated cardiovascular risk factor was a sedentary lifestyle (71.5%) after age. 57.8% of patients were not controlled at the office, with a predominance of systolic hypertension (58.2%). 61.6% of patients were controlled by ambulatory blood pressure measure, a rate of 47.8% of white coat hypertension. Glycemic control was observed in 42.2% of cases and 87% of patients had good renal function (glomerular filter rate ≥ 60 ml/mn). Therapeutic compliance was good in 53.4% of cases and dual therapy was the most used therapeutic modality 44.8% (52 patients) followed by triple therapy. The factors associated with poor blood pressure control were glycemic imbalance, non-compliance and monotherapy. Dual therapy had a protective effect. Conclusion: The association of hypertension and type 2 diabetes is frequent. The risk of occurrence increases with age. Ambulatory blood pressure measure is the best method to assess blood pressure control. Optimization of blood pressure control should also include optimization of glycemic control.展开更多
The pneumatic pressure control systems have been used in some fields. However, the researches on pneumatic pressure control mainly focus on constant pressure regulation. Poor dynamic characteristics and strong nonline...The pneumatic pressure control systems have been used in some fields. However, the researches on pneumatic pressure control mainly focus on constant pressure regulation. Poor dynamic characteristics and strong nonlinearity of such systems limit its application in the field of pressure tracking control. In order to meet the demand of generating dynamic pressure signal in the application of the hardware-in-the-loop simulation of aerospace engineering, a positive and negative pneumatic pressure servo system is provided to implement dynamic adjustment of sealed chamber pressure. A mathematical model is established with simulation and experiment being implemented afterwards to discuss the characteristics of the system, which shows serious asymmetry in the process of charging and discharging. Based on the analysis of the system dynamics, a fuzzy proportional integral derivative(PID) controller with asymmetric fuzzy compensator is proposed. Different from conventional adjusting mechanisms employing the error and change in error of the controlled variable as input parameters, the current chamber pressure and charging or discharging state are chosen as inputs of the compensator, which improves adaptability.To verify the effectiveness and performance of the proposed controller, the comparison experiments tracking sinusoidal and square wave commands are conducted.Experimental results show that the proposed controller can obtain better dynamic performance and relatively consistent control performance across the scope of work(2-140 kPa). The research proposes a fuzzy control method to overcome asymmetry and enhance adaptability for the positive and negative pneumatic pressure servo system.展开更多
In-situ pressure-preserved coring(IPP-Coring)is considered to be the most reliable and efficient method for the identification of the scale of oil and gas resources.During IPP-Coring,because the rotation behavior of t...In-situ pressure-preserved coring(IPP-Coring)is considered to be the most reliable and efficient method for the identification of the scale of oil and gas resources.During IPP-Coring,because the rotation behavior of the pressure controller valve cover in different medium environments is unclear,interference between the valve cover and inner pipe may occur and negatively affect the IPP-Coring success rate.To address this issue,we conducted a series of indoor experiments employing a high-speed camera to gain greater insights into the valve cover rotation behavior in different medium environments,e.g.,air,water,and simulated drilling fluids.The results indicated that the variation in the valve cover rotation angle in the air and fluid environments can be described by a one-phase exponential decay function with a constant time parameter and by biphasic dose response function,respectively.The rotation behavior in the fluid environments exhibited distinct elastic and gravitational acceleration zones.In the fluid environments,the density clearly impacted the valve cover closing time and rotation behavior,whereas the effect of viscosity was very slight.This can be attributed to the negligible influence of the fluid viscosity on the drag coefficient found in this study;meanwhile,the density can increase the buoyancy and the time period during which the valve cover experienced a high drag coefficient.Considering these results,control schemes for the valve cover rotation behavior during IPP-Coring were proposed for different layers and geological conditions in which the different drilling fluids should be used,e.g.,the use of a high-density valve cover in high-pore pressure layers.展开更多
Objective:The purpose of the study was to assess the clinical efficacy and safety of a combined perfusion suction platform with pressure feedback control function and an ureteroscopic suction sheath that can measure t...Objective:The purpose of the study was to assess the clinical efficacy and safety of a combined perfusion suction platform with pressure feedback control function and an ureteroscopic suction sheath that can measure the ureteropelvic pressure in implementing lithotripsies.Methods:Fifty-two patients who underwent lithotripsy under intelligent monitoring of ureteral intraluminal pressure from June 2016 to January 2018 were retrospectively recruited.The inclusion standard was stone diameter>1.5 cm but<2.5 cm.After the 12/14 Fr suction sheath was placed,manometer interface and suction interface of the sheath were connected to the platform via the pressure sensor and suction tube,respectively.The ureteroscope was connected to the platform perfusion pump,and the crushed stones were aspirated out under negative pressure.Results:According to the location of the stone,21(40.4%)cases were classified as upper ureteral stones,19(36.5%)were midureteral stones,and 12(23.1%)were lower ureteral stones.Forty-seven patients underwent successful primary sheath placement and lithotripsy with a mean operative time of 34.5(standard deviation 18.3)min.Retrograde stone migration did not occur.There were eight patients with hematuria postoperatively.Serious complication was 1.9% with one case of ureteral perforation.Stone clearance was 95.7% at Day 1e2 postoperatively,and 100% at Day 30 postoperatively.Conclusion:Ureteroscopic lithotripsy with intelligent pressure control using our device improved the efficiency of the lithotripsy and rate of stone clearance.The safety of the operation can be ensured.It is worth popularization and application in clinical practice.展开更多
Deep oil exploration coring technology cannot accurately maintain the in-situ pressure and temperature of samples, which leads to a distortion of deep oil and gas resource reserve evaluations based on conventional cor...Deep oil exploration coring technology cannot accurately maintain the in-situ pressure and temperature of samples, which leads to a distortion of deep oil and gas resource reserve evaluations based on conventional cores and cannot guide the development of deep oil and gas resources on Earth. The fundamental reason is the lack of temperature and pressure control in in-situ coring environments. In this paper, a pressure control method of a coring device is studied. The theory and method of deep intelligent temperature-pressure coupling control are innovatively proposed, and a multifield coupling dynamic sealing model is established. The optimal cardinality three term PID (Proportional-Integral-Differential) intelligent control algorithm of pressure system is developed. The temperature-pressure characteristic of the gas-liquid two-phase cavity is analyzed, and the pressure intelligent control is carried out based on three term PID control algorithms. An in-situ condition-preserved coring (ICP-Coring) device is developed, and an intelligent control system for the temperature and pressure of the coring device is designed and verified by experiments. The results show that the temperature-pressure coupling control system can effectively realize stable sealing under temperature-pressure fields of 140 MPa and 150 °C. The temperature-pressure coupling control method can accurately realize a constant pressure inside the coring device. The maximum working pressure is 140 MPa, and the effective pressure compensation range is 20 MPa. The numerical simulation experiment of pressure system control algorithm is carried out, and the optimal cardinality and three term coefficients are obtained. The pressure steady-state error is less than 0.01%. The method of temperature-pressure coupling control has guiding significance for coring device research, and is also the basis for temperature-pressure decoupling control in ICP-Coring.展开更多
Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled tr...Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled trial to evaluate whether HBPT plus support(patient education and clinician remote hypertension management)improves blood pressure control more than usual care(UC)in the Chinese population.Methods This single-center,randomized controlled study was conducted in Beijing,China.Patients aged 30-75 years were eligible for enrolment if they had blood pressure[systolic(SBP)≥140 mmHg and/or diastolic(DBP)≥90 mmHg;or SBP≥130 mmHg and/or DBP≥80 mmHg with diabetes].We recruited 190 patients randomized to either the HBPT or the UC groups for 12 weeks.The primary endpoints were blood pressure reduction and the proportion of patients achieving the target blood pressure.Results Totally,172 patients completed the study,the HBPT plus support group(n=84),and the UC group(n=88).Patients in the plus support group showed a greater reduction in mean ambulatory blood pressure than those in the UC group.The plus support group had a significantly higher proportion of patients who achieved the target blood pressure and maintained a dipper blood pressure pattern at the12th week of follow-up.Additionally,the patients in the plus support group showed lower blood pressure variability and higher drug adherence than those in the UC group.Conclusion HBPT plus additional support results in greater blood pressure reduction,better blood pressure control,a higher proportion of dipper blood pressure patterns,lower blood pressure variability,and higher drug adherence than UC.The development of telemedicine may be the cornerstone of hypertension management in primary care.展开更多
Controlled,guided munitions can reduce dispersion in the shot,while providing the capability of engaging both stationary and maneuvering targets.The Netherlands Organisation for Applied Scientific Research has develop...Controlled,guided munitions can reduce dispersion in the shot,while providing the capability of engaging both stationary and maneuvering targets.The Netherlands Organisation for Applied Scientific Research has developed a fin-less control technology called Stagnation Pressure Reaction Control(SPRC)that takes stagnation pressure air and directs it sideways to control non-spinning projectiles.In a previous study,this technology was demonstrated at Mach 2 wind-tunnel conditions to achieve up to 1.5°controllable angle of incidence for a non-spinning,aerodynamically unstable projectile-like test object.In an operational scenario,the decelerating projectile will experience a decline in control force while the simultaneous forward shift of the center of pressure increases the need for control force.Furthermore,angles of incidence exceeding 1.5°will be experienced under realistic flight conditions,especially against maneuvering targets.This work addresses these challenges and presents an operational feasibility study for a practical application of SPRC in a non-spinning mid-caliber gun-launched projectile,using experiment data on control latency and force of the earlier study.It illustrates the combined effect of the control-and stability dynamics and underlines the potential of an SPRC projectile as a precisionoperation ammunition.This research revealed that SPRC technology can stabilize and control the hypothesized projectile in a direct fire scenario against stationary and maneuvering targets.展开更多
Introduction: The management of hypertension is mostly based on pharmacotherapy and hygienic and dietary measures (HDMs) for which little data is available in Cameroon. The concern to improve the quality of life of hy...Introduction: The management of hypertension is mostly based on pharmacotherapy and hygienic and dietary measures (HDMs) for which little data is available in Cameroon. The concern to improve the quality of life of hypertensive patients led us to study the knowledge, compliance and effect of HDMs among Cameroonian hypertensive patients. Methods: This was a cross-sectional study carried out at the Douala General Hospital;the census of patients was carried out from 05 March to 10 May 2018. The data evaluated were knowledge and compliance with HDMs with an inference of their effect on blood pressure control. Results: We recruited 330 participants at mean age of 60 ± 11 years, 37.9% men;57.3% with blood pressure (BP) controlled. Out of 330 subjects, 308 (93.3%) who had been educated about dietary health measures for hypertension were assessed on knowledge, compliance and effect of these measures against 22 (6.7%) who had never heard about them. Around 85.7% of participants had good knowledge of HDMs and 78.9% had good compliance with them. There was no statistically significant influence of knowledge and compliance with HDMs on blood pressure control. Conclusion: The level of knowledge and adherence to HDMs of hypertensive patients at the Douala General Hospital was appreciable. It is however appropriate for physicians to intensify patient education on HDMs and BP control.展开更多
Objective:To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control.Methods:A retrospective analysis of 80 patients with diabetic nephropathy(diabetic nephropathy group)and an...Objective:To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control.Methods:A retrospective analysis of 80 patients with diabetic nephropathy(diabetic nephropathy group)and another 80 patients with diabetes(diabetic group)who were admitted to the Department of Nephrology and Endocrinology at our hospital from October 2021 to October 2022 was conducted.The general data of the two groups were compared,the influencing factors associated with the two groups were analyzed unilaterally,and unconditional dichotomous logistic regression was performed to analyze the influencing factors in patients with diabetic nephropathy.Results:There were no significant differences in high-density lipoprotein,systolic blood pressure,diastolic blood pressure,and creatinine between the two groups(P>0.05);however,compared with the diabetic group,the DN group had significantly elevated glycated hemoglobin,low-density lipoprotein,24-h urine protein,insulin resistance,and diabetes duration≥10 years(P<0.05).Conclusion:The clinical research on the correlation between the incidence of hypertension and the control of blood pressure in patients with diabetic nephropathy should be strengthened in order to formulate reasonable and feasible treatment plans.展开更多
To develop the pressure control algorithm for active braking of adaptive cruise control(ACC) system,a test bench with real parts of the tested vehicle is built.With the dynamic analysis of the active braking actuators...To develop the pressure control algorithm for active braking of adaptive cruise control(ACC) system,a test bench with real parts of the tested vehicle is built.With the dynamic analysis of the active braking actuators,it is demonstrated that different duty of pulse-width modulation(PWM) signals could control the pressure changing rate of the wheel cylinder.To obtain that signal,a modified proportional-integral-differential(PID) control algorithm is developed using the variable parameter method,the control value reset method,the dead zone method and the integral saturation method.Experimental results show that the delay and overshoot of the pressure response could be reduced considerably using the modified PID algorithm compared with the conventional one.The proposed pressure control algorithm could be used for the further development of the ACC's controller.展开更多
When mining extra-thick coal seams,the main cause of strong ground pressure are the high-level thick and hard strata,but as yet there is no active and effective control technology.This paper proposes the method of sub...When mining extra-thick coal seams,the main cause of strong ground pressure are the high-level thick and hard strata,but as yet there is no active and effective control technology.This paper proposes the method of subjecting hard roofs to ground fracturing,and physical simulation is used to study the control effect of ground fracturing on the strata structure and energy release.The results show that ground fracturing changes the structural characteristics of the strata and reduces the energy release intensity and the spatial extent of overburden movement,thereby exerting significant control on the ground pressure.The Datong mining area in China is selected as the engineering background.An engineering test was conducted on site by ground horizontal well fracturing,and a 20-m-thick hard rock layer located 110 m vertically above the coal seam was targeted as the fracturing layer.On-site microseismic monitoring shows that the crack propagation length is up to 216 m and the height is up to 50 m.On-site mine pressure monitoring shows that(1)the roadway deformation is reduced to 100 mm,(2)the periodic weighting characteristics of the hydraulic supports are not obvious,and(3)the ground pressure in the working face is controlled significantly,thereby showing that the ground fracturing is successful.Ground fracturing changed the breaking characteristics of the high-level hard strata,thereby helping to ameliorate the stress concentration in the stope and providing an effective control approach for hard rock.展开更多
In situ pressure-preserved coring(IPP-Coring)technology is considered one of the most efficient methods for assessing resources.However,seal failure caused by the rotation of pressure controllers greatly affects the s...In situ pressure-preserved coring(IPP-Coring)technology is considered one of the most efficient methods for assessing resources.However,seal failure caused by the rotation of pressure controllers greatly affects the success of pressure coring.In this paper,a novel spherical-cylindrical shell pressure controller was proposed.The finite element analysis model was used to analyze the stress distribution and deformation characteristics of the pressure controller at different rotation angles.The seal failure mechanism caused by the rotation of the pressure controller was discussed.The stress deviation rate was defined to quantitatively characterize the stress concentration.Based on the test equipment designed in this laboratory,the ultimate bearing strength of the pressure controller was tested.The results show that the rotation of the valve cover causes an increase in the deformation on its lower side.Furthermore,the specific sealing pressure in the weak zone is greatly reduced by a statistically significant amount,resulting in seal failure.When the valve cover rotates 5°around the major axis,the stress deviation rate is-92.6%.To prevent rotating failure of the pressure controller,it is necessary to control the rotation angle of the valve cover within 1°around the major axis.The results of this research can help engineers reduce failure-related accidents,provide countermeasures for pressure coring,and contribute to the exploration and evaluation of deep oil and gas resources.展开更多
Acute stress concentration plays an important role in plaque rupture and may cause stroke or myocardial infarction.Quantitative evaluation of the relation between in vivo plaque stress and variations in blood pressure...Acute stress concentration plays an important role in plaque rupture and may cause stroke or myocardial infarction.Quantitative evaluation of the relation between in vivo plaque stress and variations in blood pressure and flow rates is valuable to optimize daily monitoring of the cardiovascular system for high-risk patients as well as to set a safe physical exercise intensity for better quality of life.In this study,we constructed an in vivo stress model for a human carotid bifurcation with atherosclerotic plaque,and analyzed the effects of blood pressure,flow rates,plaque stiffness,and stenosis on the elastic stress and fluid viscous stress around the plaque.According to the maximum values of the mechanical stress,we define a risk index to predict the risk level of plaque rupture under different exercise intensities.For a carotid bifurcation where the blood flow divides,the results suggest that the stenosis ratio determines the ratio of the contributions of elastic shear stress and viscous shear stress to plaque rupture.A n increase of the plaque stiffness enhances the maximum elastic shear stress in the plaque,indicating that a high-stiffness plaque is more prone to rupture for given stenosis ratio.High stress co-localization at the shoulder of plaques agrees with the region of plaque injury in clinical observations.It is demonstrated that,due to the stress-shield effect,the rupture risk of a high-stiffness plaque tends to decrease under high-stenosis conditions,suggesting the existence of a specific stenosis corresponding to the maximum risk.This study may help to complement risk stratification of vulnerable plaques in clinical practice and provides a stenosis mechanical property-specific guide for blood pressure control in cardiovascular health management.展开更多
This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products....This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products.The past test results using this method showed a casting yield of 90% to 95%,while conventional methods only show a casting yield of 60% to 70%.Although the press casting method does not require a sprue cup or runner channel casting defects such as metal penetration are often caused by the high pressure in the high-velocity pressing part of this casting process.Therefore,we proposed a pressure control method with a mathematical model of molten metal pressure,and with it we achieved experimental confirmation of the successful production of brake drums at different pressing temperatures.Results show that the proposed pressing control method can realize sound,penetration-free casting production.However,the theoretical analysis and design of this pressing process had not previously been studied sufficiently,and therefore this paper presents the theoretical design algorithm for the process as well as its experimental confirmation.展开更多
A Continuously Variable Transmission (CVT) is a type of transmissions that provides a continuous range of speed ratios, thus it allows increasing the overall powertrain efficiency by running the engine at the optimal ...A Continuously Variable Transmission (CVT) is a type of transmissions that provides a continuous range of speed ratios, thus it allows increasing the overall powertrain efficiency by running the engine at the optimal operating points. This paper investigates implementing a model based hydraulic pressure controller to achieve the desired CVT gear ratio. A map of desired gear ratios was estimated using the Optimal Operating Line (OOL) strategy, which minimizes the engine fuel consumption according to a defined cost function and a set of systems constraints. The controller was implemented in a complete vehicle model that includes driver, powertrain and road load models. The model was subjected to two different driving cycles and the results demonstrate the effectiveness of the control strategy and the pressure controller in keeping the engine at the most efficient operating regions.展开更多
Objective To investigate the role of decompressive craniectomy (DC) to decrease intractable intracranial hypertension(ICH) due to diffuse brain swelling and / or cerebral edema after severe traumatic brain injury and ...Objective To investigate the role of decompressive craniectomy (DC) to decrease intractable intracranial hypertension(ICH) due to diffuse brain swelling and / or cerebral edema after severe traumatic brain injury and the time window of DC to affect on prognosis. Methods The clinical record of 132 patients who underwent DC for posttraumatic intractable ICH in our hospital from July 2003 to展开更多
Objective:Home blood pressure monitoring(HBPM)is viewed as a facilitating factor in the initial diagnosis and long-term management of treated hypertension.However,evidence remains scarce about the effectiveness of HBP...Objective:Home blood pressure monitoring(HBPM)is viewed as a facilitating factor in the initial diagnosis and long-term management of treated hypertension.However,evidence remains scarce about the effectiveness of HBPM use in the real world.This study aimed to examine the associations of HBPM use with blood pressure(BP)control and medication adherence.Methods:This prospective cohort study included hypertensive patients with high cardiovascular risk who were aged≥50 years.At baseline,information about types of BP monitor,frequency of HBPM,perception of anti-hypertensive treatment,and measured office BP were collected.During the 1-year follow-up(visits at 1,2,3,6,and 12 months),information on medication adherence was collected at each visit.The 2 major outcomes were BP control at baseline and medication adherence during the 1-year follow-up.A log-binomial regression model was used to examine the association between frequency of HBPM and outcomes,stratified by the perceptions of anti-hypertensive treatment.Results:A total of 5,363 hypertensive patients were included in the analysis.The age was(64.6±7.2)years,and 41.2%(2,208)were female.Of the total patients,85.9%(4,606)had a home BP monitor and 47.8%(2,564)had an incorrect perception of anti-hypertensive treatment.Overall,24.2%(1,299)of patients monitored their BP daily,37.6%(2,015)weekly,17.3%(926)monthly,and 20.9%(1,123)less than monthly.At baseline,the systolic BP and diastolic BP were(146.6±10.8)mmHg and(81.9±10.6)mmHg,respectively,and 28.5%(1,527)of patients had their BP controlled.Regardless of whether the patients had correct or incorrect perceptions of anti-hypertensive treatment,there is no significant association between HBPM frequency and BP control at baseline.During the 1-year follow-up,23.9%(1,280)of patients had non-adherence to medications at least once.In patients with an incorrect perception of anti-hypertensive treatment,those monitoring BP most frequently(daily)had the highest non-adherence rate(29.9%,175/585).Compared with those monitoring their BP less than monthly,patients who monitored their BP daily were more likely not to adhere to anti-hypertensive medications(adjusted relative risk=1.38,95%confidence interval:1.11–1.72,P=0.004).Conclusions:HBPM performance among hypertensive patients in China is,in general,sub-optimal.No association was observed between using HBPM alone and hypertension control,indicating that the effects of HBPM could be conditional.Patients’misconceptions about anti-hypertensive treatment may impair the role of BP monitoring in achieving medication adherence.Fully incorporating the correct perception of hypertension into the management of hypertensive patients is needed.展开更多
A novel miniature pressure regulator is fabricated and studied. The regulator can easily be integrated into portable mechatronics or miniature robotic applications because of its lightweight and compact size. An espec...A novel miniature pressure regulator is fabricated and studied. The regulator can easily be integrated into portable mechatronics or miniature robotic applications because of its lightweight and compact size. An especial poppet is designed to minimize its size and to withstand high-pressure. The pressure regulator is designed for a hopping robot which is powered by a combustion system. The hopping robot has great moving capacities such as jumping over big obstacles,walls and ditches. The regulator helps the hopping robot to decrease size and weight,and to sustain high pressure of oxygen and fuel tank. It will maintain constant output pressure to obtain suitable proportion of oxygen and fuel in the combustion cylinder. Dynamic simulation of the miniature pneumatic pressure regulator is performed. Experiments on prototype of miniature pneumatic pressure regulator are also carried out to validate the performance and satisfied performance is obtained.展开更多
Objective To evaluate the effect of a workplace-based comprehensive intervention strategy on the improvement of blood pressure (BP) control.Methods A cluster controlled trail, with workplaces (clusters)assigned to eit...Objective To evaluate the effect of a workplace-based comprehensive intervention strategy on the improvement of blood pressure (BP) control.Methods A cluster controlled trail, with workplaces (clusters)assigned to either the intervention or control group. Totally, 30 statedowned enterprises across China were included, among which 20were allocated to the intervention group and 10 to the control group.展开更多
文摘The performance of the designed digital electro-pneumatic cabin pressure control system for the cabin pressure schedule of transport aircraft is investigated.For the purpose of this study,an experimental setup consisting of a simulated hermetic cabin and altitude simulation chamber is configured for cabin pressure control system operation.A series of experimental tests are executed to evaluate the performance of the cabin pressure control system.The parameters of the PID controller are optimized.In the optimization process,the variation regularity of the rate of cabin pressure change under various conditions is considered.An approach to prioritize the control of the rate of change of cabin pressure based on the flight status model is proposed and verified experimentally.The experimental results indicate that the proposed approach can be adopted for the designed digital electro-pneumatic cabin pressure control system to obtain a better cabin pressure schedule and rate of cabin pressure change.
文摘Objective: The association hypertension and diabetes is important. The two pathologies may influence each other. The aim was to study the correlation between glycemic control and blood pressure control and to determine the factors associated with blood pressure control. Methodology: This was a descriptive cross-sectional study with an analytical focus over 7 months. Patients were recruited as outpatients and all underwent ambulatory blood pressure measure, glycated hemoglobin and creatinine measurements, and assessment of compliance with treatment. Results: During this period 116 patients were collected. The predominance was female 69%. The mean age of the patients was 62 ± 7 years with a peak between 60 and 70 years. The average age of hypertension was 12 years and that of diabetes 6 1/2 years. The most frequently associated cardiovascular risk factor was a sedentary lifestyle (71.5%) after age. 57.8% of patients were not controlled at the office, with a predominance of systolic hypertension (58.2%). 61.6% of patients were controlled by ambulatory blood pressure measure, a rate of 47.8% of white coat hypertension. Glycemic control was observed in 42.2% of cases and 87% of patients had good renal function (glomerular filter rate ≥ 60 ml/mn). Therapeutic compliance was good in 53.4% of cases and dual therapy was the most used therapeutic modality 44.8% (52 patients) followed by triple therapy. The factors associated with poor blood pressure control were glycemic imbalance, non-compliance and monotherapy. Dual therapy had a protective effect. Conclusion: The association of hypertension and type 2 diabetes is frequent. The risk of occurrence increases with age. Ambulatory blood pressure measure is the best method to assess blood pressure control. Optimization of blood pressure control should also include optimization of glycemic control.
基金Supported by National Natural Science Foundation of China(Grant No.51575199)
文摘The pneumatic pressure control systems have been used in some fields. However, the researches on pneumatic pressure control mainly focus on constant pressure regulation. Poor dynamic characteristics and strong nonlinearity of such systems limit its application in the field of pressure tracking control. In order to meet the demand of generating dynamic pressure signal in the application of the hardware-in-the-loop simulation of aerospace engineering, a positive and negative pneumatic pressure servo system is provided to implement dynamic adjustment of sealed chamber pressure. A mathematical model is established with simulation and experiment being implemented afterwards to discuss the characteristics of the system, which shows serious asymmetry in the process of charging and discharging. Based on the analysis of the system dynamics, a fuzzy proportional integral derivative(PID) controller with asymmetric fuzzy compensator is proposed. Different from conventional adjusting mechanisms employing the error and change in error of the controlled variable as input parameters, the current chamber pressure and charging or discharging state are chosen as inputs of the compensator, which improves adaptability.To verify the effectiveness and performance of the proposed controller, the comparison experiments tracking sinusoidal and square wave commands are conducted.Experimental results show that the proposed controller can obtain better dynamic performance and relatively consistent control performance across the scope of work(2-140 kPa). The research proposes a fuzzy control method to overcome asymmetry and enhance adaptability for the positive and negative pneumatic pressure servo system.
基金The authors are grateful for the financial support from the National Natural Science Foundation of China(No.51827901&No.52274133)the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)the Shenzhen National Science Fund for Distinguished Young Scholars(RCJC20210706091948015).
文摘In-situ pressure-preserved coring(IPP-Coring)is considered to be the most reliable and efficient method for the identification of the scale of oil and gas resources.During IPP-Coring,because the rotation behavior of the pressure controller valve cover in different medium environments is unclear,interference between the valve cover and inner pipe may occur and negatively affect the IPP-Coring success rate.To address this issue,we conducted a series of indoor experiments employing a high-speed camera to gain greater insights into the valve cover rotation behavior in different medium environments,e.g.,air,water,and simulated drilling fluids.The results indicated that the variation in the valve cover rotation angle in the air and fluid environments can be described by a one-phase exponential decay function with a constant time parameter and by biphasic dose response function,respectively.The rotation behavior in the fluid environments exhibited distinct elastic and gravitational acceleration zones.In the fluid environments,the density clearly impacted the valve cover closing time and rotation behavior,whereas the effect of viscosity was very slight.This can be attributed to the negligible influence of the fluid viscosity on the drag coefficient found in this study;meanwhile,the density can increase the buoyancy and the time period during which the valve cover experienced a high drag coefficient.Considering these results,control schemes for the valve cover rotation behavior during IPP-Coring were proposed for different layers and geological conditions in which the different drilling fluids should be used,e.g.,the use of a high-density valve cover in high-pore pressure layers.
基金This study was funded by Major Science and Technology Projects of Jiangxi Provincial Science and Technology Department(20152ACG70009).
文摘Objective:The purpose of the study was to assess the clinical efficacy and safety of a combined perfusion suction platform with pressure feedback control function and an ureteroscopic suction sheath that can measure the ureteropelvic pressure in implementing lithotripsies.Methods:Fifty-two patients who underwent lithotripsy under intelligent monitoring of ureteral intraluminal pressure from June 2016 to January 2018 were retrospectively recruited.The inclusion standard was stone diameter>1.5 cm but<2.5 cm.After the 12/14 Fr suction sheath was placed,manometer interface and suction interface of the sheath were connected to the platform via the pressure sensor and suction tube,respectively.The ureteroscope was connected to the platform perfusion pump,and the crushed stones were aspirated out under negative pressure.Results:According to the location of the stone,21(40.4%)cases were classified as upper ureteral stones,19(36.5%)were midureteral stones,and 12(23.1%)were lower ureteral stones.Forty-seven patients underwent successful primary sheath placement and lithotripsy with a mean operative time of 34.5(standard deviation 18.3)min.Retrograde stone migration did not occur.There were eight patients with hematuria postoperatively.Serious complication was 1.9% with one case of ureteral perforation.Stone clearance was 95.7% at Day 1e2 postoperatively,and 100% at Day 30 postoperatively.Conclusion:Ureteroscopic lithotripsy with intelligent pressure control using our device improved the efficiency of the lithotripsy and rate of stone clearance.The safety of the operation can be ensured.It is worth popularization and application in clinical practice.
基金supported by the National Natural Science Foundation of China(grant numbers 51827901,51805340)funded by the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)Shenzhen Basic Research Program(General Program)(No.JCYJ20190808153416970).
文摘Deep oil exploration coring technology cannot accurately maintain the in-situ pressure and temperature of samples, which leads to a distortion of deep oil and gas resource reserve evaluations based on conventional cores and cannot guide the development of deep oil and gas resources on Earth. The fundamental reason is the lack of temperature and pressure control in in-situ coring environments. In this paper, a pressure control method of a coring device is studied. The theory and method of deep intelligent temperature-pressure coupling control are innovatively proposed, and a multifield coupling dynamic sealing model is established. The optimal cardinality three term PID (Proportional-Integral-Differential) intelligent control algorithm of pressure system is developed. The temperature-pressure characteristic of the gas-liquid two-phase cavity is analyzed, and the pressure intelligent control is carried out based on three term PID control algorithms. An in-situ condition-preserved coring (ICP-Coring) device is developed, and an intelligent control system for the temperature and pressure of the coring device is designed and verified by experiments. The results show that the temperature-pressure coupling control system can effectively realize stable sealing under temperature-pressure fields of 140 MPa and 150 °C. The temperature-pressure coupling control method can accurately realize a constant pressure inside the coring device. The maximum working pressure is 140 MPa, and the effective pressure compensation range is 20 MPa. The numerical simulation experiment of pressure system control algorithm is carried out, and the optimal cardinality and three term coefficients are obtained. The pressure steady-state error is less than 0.01%. The method of temperature-pressure coupling control has guiding significance for coring device research, and is also the basis for temperature-pressure decoupling control in ICP-Coring.
基金The Project of the National Ministry of Industry and Information Technology[2020-0103-3-1-1]The Project of Beijing Science and technology“capital characteristics”[Z181100001718007]。
文摘Objective Current clinical evidence on the effects of home blood pressure telemonitoring(HBPT)on improving blood pressure control comes entirely from developed countries.Thus,we performed this randomized controlled trial to evaluate whether HBPT plus support(patient education and clinician remote hypertension management)improves blood pressure control more than usual care(UC)in the Chinese population.Methods This single-center,randomized controlled study was conducted in Beijing,China.Patients aged 30-75 years were eligible for enrolment if they had blood pressure[systolic(SBP)≥140 mmHg and/or diastolic(DBP)≥90 mmHg;or SBP≥130 mmHg and/or DBP≥80 mmHg with diabetes].We recruited 190 patients randomized to either the HBPT or the UC groups for 12 weeks.The primary endpoints were blood pressure reduction and the proportion of patients achieving the target blood pressure.Results Totally,172 patients completed the study,the HBPT plus support group(n=84),and the UC group(n=88).Patients in the plus support group showed a greater reduction in mean ambulatory blood pressure than those in the UC group.The plus support group had a significantly higher proportion of patients who achieved the target blood pressure and maintained a dipper blood pressure pattern at the12th week of follow-up.Additionally,the patients in the plus support group showed lower blood pressure variability and higher drug adherence than those in the UC group.Conclusion HBPT plus additional support results in greater blood pressure reduction,better blood pressure control,a higher proportion of dipper blood pressure patterns,lower blood pressure variability,and higher drug adherence than UC.The development of telemedicine may be the cornerstone of hypertension management in primary care.
文摘Controlled,guided munitions can reduce dispersion in the shot,while providing the capability of engaging both stationary and maneuvering targets.The Netherlands Organisation for Applied Scientific Research has developed a fin-less control technology called Stagnation Pressure Reaction Control(SPRC)that takes stagnation pressure air and directs it sideways to control non-spinning projectiles.In a previous study,this technology was demonstrated at Mach 2 wind-tunnel conditions to achieve up to 1.5°controllable angle of incidence for a non-spinning,aerodynamically unstable projectile-like test object.In an operational scenario,the decelerating projectile will experience a decline in control force while the simultaneous forward shift of the center of pressure increases the need for control force.Furthermore,angles of incidence exceeding 1.5°will be experienced under realistic flight conditions,especially against maneuvering targets.This work addresses these challenges and presents an operational feasibility study for a practical application of SPRC in a non-spinning mid-caliber gun-launched projectile,using experiment data on control latency and force of the earlier study.It illustrates the combined effect of the control-and stability dynamics and underlines the potential of an SPRC projectile as a precisionoperation ammunition.This research revealed that SPRC technology can stabilize and control the hypothesized projectile in a direct fire scenario against stationary and maneuvering targets.
文摘Introduction: The management of hypertension is mostly based on pharmacotherapy and hygienic and dietary measures (HDMs) for which little data is available in Cameroon. The concern to improve the quality of life of hypertensive patients led us to study the knowledge, compliance and effect of HDMs among Cameroonian hypertensive patients. Methods: This was a cross-sectional study carried out at the Douala General Hospital;the census of patients was carried out from 05 March to 10 May 2018. The data evaluated were knowledge and compliance with HDMs with an inference of their effect on blood pressure control. Results: We recruited 330 participants at mean age of 60 ± 11 years, 37.9% men;57.3% with blood pressure (BP) controlled. Out of 330 subjects, 308 (93.3%) who had been educated about dietary health measures for hypertension were assessed on knowledge, compliance and effect of these measures against 22 (6.7%) who had never heard about them. Around 85.7% of participants had good knowledge of HDMs and 78.9% had good compliance with them. There was no statistically significant influence of knowledge and compliance with HDMs on blood pressure control. Conclusion: The level of knowledge and adherence to HDMs of hypertensive patients at the Douala General Hospital was appreciable. It is however appropriate for physicians to intensify patient education on HDMs and BP control.
文摘Objective:To explore the risk factors of diabetic nephropathy and its correlation with blood pressure control.Methods:A retrospective analysis of 80 patients with diabetic nephropathy(diabetic nephropathy group)and another 80 patients with diabetes(diabetic group)who were admitted to the Department of Nephrology and Endocrinology at our hospital from October 2021 to October 2022 was conducted.The general data of the two groups were compared,the influencing factors associated with the two groups were analyzed unilaterally,and unconditional dichotomous logistic regression was performed to analyze the influencing factors in patients with diabetic nephropathy.Results:There were no significant differences in high-density lipoprotein,systolic blood pressure,diastolic blood pressure,and creatinine between the two groups(P>0.05);however,compared with the diabetic group,the DN group had significantly elevated glycated hemoglobin,low-density lipoprotein,24-h urine protein,insulin resistance,and diabetes duration≥10 years(P<0.05).Conclusion:The clinical research on the correlation between the incidence of hypertension and the control of blood pressure in patients with diabetic nephropathy should be strengthened in order to formulate reasonable and feasible treatment plans.
基金Supported by the Ministerial Level Advanced Research Foundation(40401040302)
文摘To develop the pressure control algorithm for active braking of adaptive cruise control(ACC) system,a test bench with real parts of the tested vehicle is built.With the dynamic analysis of the active braking actuators,it is demonstrated that different duty of pulse-width modulation(PWM) signals could control the pressure changing rate of the wheel cylinder.To obtain that signal,a modified proportional-integral-differential(PID) control algorithm is developed using the variable parameter method,the control value reset method,the dead zone method and the integral saturation method.Experimental results show that the delay and overshoot of the pressure response could be reduced considerably using the modified PID algorithm compared with the conventional one.The proposed pressure control algorithm could be used for the further development of the ACC's controller.
基金This work was supported by the State Key Research Development Program of China(Grant No.2018YFC0604500,2018YFC0604506)by the China Postdoctoral Science Foundation(Grant No.2019M651080)+3 种基金as an applied basic research Project of Shanxi Province(Grant No.201901D211030)by the Scientific,Technological Innovation Programs of Higher Education Institutions in Shanxi(STIP)(Grant No.2019L0208)as a Major Program in Shanxi Province(Grant No.20191101015)as a Distinguished Youth Funds of National Natural Science Foundation of China(No.51925402).
文摘When mining extra-thick coal seams,the main cause of strong ground pressure are the high-level thick and hard strata,but as yet there is no active and effective control technology.This paper proposes the method of subjecting hard roofs to ground fracturing,and physical simulation is used to study the control effect of ground fracturing on the strata structure and energy release.The results show that ground fracturing changes the structural characteristics of the strata and reduces the energy release intensity and the spatial extent of overburden movement,thereby exerting significant control on the ground pressure.The Datong mining area in China is selected as the engineering background.An engineering test was conducted on site by ground horizontal well fracturing,and a 20-m-thick hard rock layer located 110 m vertically above the coal seam was targeted as the fracturing layer.On-site microseismic monitoring shows that the crack propagation length is up to 216 m and the height is up to 50 m.On-site mine pressure monitoring shows that(1)the roadway deformation is reduced to 100 mm,(2)the periodic weighting characteristics of the hydraulic supports are not obvious,and(3)the ground pressure in the working face is controlled significantly,thereby showing that the ground fracturing is successful.Ground fracturing changed the breaking characteristics of the high-level hard strata,thereby helping to ameliorate the stress concentration in the stope and providing an effective control approach for hard rock.
基金supported by the Program for Guangdong Introducing Innovative and Enterpreneurial Teams(No.2019ZT08G315)National Natural Science Foundation of China No.51827901 and U2013603
文摘In situ pressure-preserved coring(IPP-Coring)technology is considered one of the most efficient methods for assessing resources.However,seal failure caused by the rotation of pressure controllers greatly affects the success of pressure coring.In this paper,a novel spherical-cylindrical shell pressure controller was proposed.The finite element analysis model was used to analyze the stress distribution and deformation characteristics of the pressure controller at different rotation angles.The seal failure mechanism caused by the rotation of the pressure controller was discussed.The stress deviation rate was defined to quantitatively characterize the stress concentration.Based on the test equipment designed in this laboratory,the ultimate bearing strength of the pressure controller was tested.The results show that the rotation of the valve cover causes an increase in the deformation on its lower side.Furthermore,the specific sealing pressure in the weak zone is greatly reduced by a statistically significant amount,resulting in seal failure.When the valve cover rotates 5°around the major axis,the stress deviation rate is-92.6%.To prevent rotating failure of the pressure controller,it is necessary to control the rotation angle of the valve cover within 1°around the major axis.The results of this research can help engineers reduce failure-related accidents,provide countermeasures for pressure coring,and contribute to the exploration and evaluation of deep oil and gas resources.
基金This work was supported by the National Key R&D Program of China(Grant 2017YFE0117100)the National Natural Science Foundation of China(Grants 11872040 and 11232010)+1 种基金the Outstanding Clinical Discipline Project of Shanghai Pudong(Grant PWYgy-2018-08)the Science and Technology Commission of Shanghai Municipality(Grant 18ZR1433900).
文摘Acute stress concentration plays an important role in plaque rupture and may cause stroke or myocardial infarction.Quantitative evaluation of the relation between in vivo plaque stress and variations in blood pressure and flow rates is valuable to optimize daily monitoring of the cardiovascular system for high-risk patients as well as to set a safe physical exercise intensity for better quality of life.In this study,we constructed an in vivo stress model for a human carotid bifurcation with atherosclerotic plaque,and analyzed the effects of blood pressure,flow rates,plaque stiffness,and stenosis on the elastic stress and fluid viscous stress around the plaque.According to the maximum values of the mechanical stress,we define a risk index to predict the risk level of plaque rupture under different exercise intensities.For a carotid bifurcation where the blood flow divides,the results suggest that the stenosis ratio determines the ratio of the contributions of elastic shear stress and viscous shear stress to plaque rupture.A n increase of the plaque stiffness enhances the maximum elastic shear stress in the plaque,indicating that a high-stiffness plaque is more prone to rupture for given stenosis ratio.High stress co-localization at the shoulder of plaques agrees with the region of plaque injury in clinical observations.It is demonstrated that,due to the stress-shield effect,the rupture risk of a high-stiffness plaque tends to decrease under high-stenosis conditions,suggesting the existence of a specific stenosis corresponding to the maximum risk.This study may help to complement risk stratification of vulnerable plaques in clinical practice and provides a stenosis mechanical property-specific guide for blood pressure control in cardiovascular health management.
文摘This paper presents a technique for controlling the pressure of a molten metal when using a new type of iron casting method called sand mold press casting to realize high productivity and obtain high-quality products.The past test results using this method showed a casting yield of 90% to 95%,while conventional methods only show a casting yield of 60% to 70%.Although the press casting method does not require a sprue cup or runner channel casting defects such as metal penetration are often caused by the high pressure in the high-velocity pressing part of this casting process.Therefore,we proposed a pressure control method with a mathematical model of molten metal pressure,and with it we achieved experimental confirmation of the successful production of brake drums at different pressing temperatures.Results show that the proposed pressing control method can realize sound,penetration-free casting production.However,the theoretical analysis and design of this pressing process had not previously been studied sufficiently,and therefore this paper presents the theoretical design algorithm for the process as well as its experimental confirmation.
文摘A Continuously Variable Transmission (CVT) is a type of transmissions that provides a continuous range of speed ratios, thus it allows increasing the overall powertrain efficiency by running the engine at the optimal operating points. This paper investigates implementing a model based hydraulic pressure controller to achieve the desired CVT gear ratio. A map of desired gear ratios was estimated using the Optimal Operating Line (OOL) strategy, which minimizes the engine fuel consumption according to a defined cost function and a set of systems constraints. The controller was implemented in a complete vehicle model that includes driver, powertrain and road load models. The model was subjected to two different driving cycles and the results demonstrate the effectiveness of the control strategy and the pressure controller in keeping the engine at the most efficient operating regions.
文摘Objective To investigate the role of decompressive craniectomy (DC) to decrease intractable intracranial hypertension(ICH) due to diffuse brain swelling and / or cerebral edema after severe traumatic brain injury and the time window of DC to affect on prognosis. Methods The clinical record of 132 patients who underwent DC for posttraumatic intractable ICH in our hospital from July 2003 to
基金supported by the National Key Research and Development Program of China(2018YFC1312404,2018YFC1312400)by the National Clinical Research Center for Cardiovascular Diseases,Fuwai Hospital,Chinese Academy of Medical Sciences(NCRC2021001).
文摘Objective:Home blood pressure monitoring(HBPM)is viewed as a facilitating factor in the initial diagnosis and long-term management of treated hypertension.However,evidence remains scarce about the effectiveness of HBPM use in the real world.This study aimed to examine the associations of HBPM use with blood pressure(BP)control and medication adherence.Methods:This prospective cohort study included hypertensive patients with high cardiovascular risk who were aged≥50 years.At baseline,information about types of BP monitor,frequency of HBPM,perception of anti-hypertensive treatment,and measured office BP were collected.During the 1-year follow-up(visits at 1,2,3,6,and 12 months),information on medication adherence was collected at each visit.The 2 major outcomes were BP control at baseline and medication adherence during the 1-year follow-up.A log-binomial regression model was used to examine the association between frequency of HBPM and outcomes,stratified by the perceptions of anti-hypertensive treatment.Results:A total of 5,363 hypertensive patients were included in the analysis.The age was(64.6±7.2)years,and 41.2%(2,208)were female.Of the total patients,85.9%(4,606)had a home BP monitor and 47.8%(2,564)had an incorrect perception of anti-hypertensive treatment.Overall,24.2%(1,299)of patients monitored their BP daily,37.6%(2,015)weekly,17.3%(926)monthly,and 20.9%(1,123)less than monthly.At baseline,the systolic BP and diastolic BP were(146.6±10.8)mmHg and(81.9±10.6)mmHg,respectively,and 28.5%(1,527)of patients had their BP controlled.Regardless of whether the patients had correct or incorrect perceptions of anti-hypertensive treatment,there is no significant association between HBPM frequency and BP control at baseline.During the 1-year follow-up,23.9%(1,280)of patients had non-adherence to medications at least once.In patients with an incorrect perception of anti-hypertensive treatment,those monitoring BP most frequently(daily)had the highest non-adherence rate(29.9%,175/585).Compared with those monitoring their BP less than monthly,patients who monitored their BP daily were more likely not to adhere to anti-hypertensive medications(adjusted relative risk=1.38,95%confidence interval:1.11–1.72,P=0.004).Conclusions:HBPM performance among hypertensive patients in China is,in general,sub-optimal.No association was observed between using HBPM alone and hypertension control,indicating that the effects of HBPM could be conditional.Patients’misconceptions about anti-hypertensive treatment may impair the role of BP monitoring in achieving medication adherence.Fully incorporating the correct perception of hypertension into the management of hypertensive patients is needed.
文摘A novel miniature pressure regulator is fabricated and studied. The regulator can easily be integrated into portable mechatronics or miniature robotic applications because of its lightweight and compact size. An especial poppet is designed to minimize its size and to withstand high-pressure. The pressure regulator is designed for a hopping robot which is powered by a combustion system. The hopping robot has great moving capacities such as jumping over big obstacles,walls and ditches. The regulator helps the hopping robot to decrease size and weight,and to sustain high pressure of oxygen and fuel tank. It will maintain constant output pressure to obtain suitable proportion of oxygen and fuel in the combustion cylinder. Dynamic simulation of the miniature pneumatic pressure regulator is performed. Experiments on prototype of miniature pneumatic pressure regulator are also carried out to validate the performance and satisfied performance is obtained.
文摘Objective To evaluate the effect of a workplace-based comprehensive intervention strategy on the improvement of blood pressure (BP) control.Methods A cluster controlled trail, with workplaces (clusters)assigned to either the intervention or control group. Totally, 30 statedowned enterprises across China were included, among which 20were allocated to the intervention group and 10 to the control group.