Background:This study was aimed to investigate whether patients with epilepsy(PWE)have higher depression and anxiety levels than the normal population in low-risk areas for coronavirus disease 2019(COVID-19)in the nor...Background:This study was aimed to investigate whether patients with epilepsy(PWE)have higher depression and anxiety levels than the normal population in low-risk areas for coronavirus disease 2019(COVID-19)in the northern part of Guizhou Province,China,during the COVID-19 epidemic,to evaluate their knowledge on COVID-19,and to analyze related factors for the psychological distress of PWE at this special time.Methods:The survey was conducted online from February 28,2020 to March 7,2020 via a questionnaire.PWE from the outpatient clinic of epilepsy of the Aflited Hospital of Zunyi Medical University,and healthy people matched for age and sex,participated in this study.Mental health was assessed via a generalized anxiety self-rating scale(GAD-7)and the self-rating depression scale(PHQ-9).The knowledge of COVID-19 in both groups was investigated.Results:There were no significant differences in the general demographics between the PWE and healthy control groups.The scores of PHQ-9(P<0.01)and GAD-7(P<0.001)were higher in the PWE group than in the healthy group.There was a signifcant difference in the proportions of respondents with different severities of depression and anxi-ety,between the two groups,which revealed significantly higher degree of depression and anxiety in PWE than in healthy people(P=0,P=0).Overwhelming awareness and stressful concerns for the pandemic and female patients with epilepsy were key factors that affect the level of anxiety and depression in PWE.Further,the PWE had less accu-rate knowledge of COVID-19 than healthy people(P<0.001).There was no statistically signifcant difference between the two groups in the knowledge of virus transmission route,incubation period,susceptible population,transmis-sion speed,clinical characteristics,and isolation measures on COVID-19(P>0.05).PWE knew less about some of the prevention and control measures of COVID-19 than healthy people.Conclusions:During the COVID-19 epidemic,excessive attention to the epidemic and the female sex are factors associated with anxiety and depression in PWE,even in low-risk areas.展开更多
基金the Collaborative Innovation Center of Chinese Ministry of Education(2020-39).
文摘Background:This study was aimed to investigate whether patients with epilepsy(PWE)have higher depression and anxiety levels than the normal population in low-risk areas for coronavirus disease 2019(COVID-19)in the northern part of Guizhou Province,China,during the COVID-19 epidemic,to evaluate their knowledge on COVID-19,and to analyze related factors for the psychological distress of PWE at this special time.Methods:The survey was conducted online from February 28,2020 to March 7,2020 via a questionnaire.PWE from the outpatient clinic of epilepsy of the Aflited Hospital of Zunyi Medical University,and healthy people matched for age and sex,participated in this study.Mental health was assessed via a generalized anxiety self-rating scale(GAD-7)and the self-rating depression scale(PHQ-9).The knowledge of COVID-19 in both groups was investigated.Results:There were no significant differences in the general demographics between the PWE and healthy control groups.The scores of PHQ-9(P<0.01)and GAD-7(P<0.001)were higher in the PWE group than in the healthy group.There was a signifcant difference in the proportions of respondents with different severities of depression and anxi-ety,between the two groups,which revealed significantly higher degree of depression and anxiety in PWE than in healthy people(P=0,P=0).Overwhelming awareness and stressful concerns for the pandemic and female patients with epilepsy were key factors that affect the level of anxiety and depression in PWE.Further,the PWE had less accu-rate knowledge of COVID-19 than healthy people(P<0.001).There was no statistically signifcant difference between the two groups in the knowledge of virus transmission route,incubation period,susceptible population,transmis-sion speed,clinical characteristics,and isolation measures on COVID-19(P>0.05).PWE knew less about some of the prevention and control measures of COVID-19 than healthy people.Conclusions:During the COVID-19 epidemic,excessive attention to the epidemic and the female sex are factors associated with anxiety and depression in PWE,even in low-risk areas.
