In this paper our studies about the sequential testing program for predicting and identificating carcinogens, sequential discriminant method and cost- effectiveness analysis are summarized. The analysis of our databas...In this paper our studies about the sequential testing program for predicting and identificating carcinogens, sequential discriminant method and cost- effectiveness analysis are summarized. The analysis of our database of carcinogeniclty and genotoxicity of chemicals demonstrates the uncertainty . of short- term tests ( STTs ) to predict carcinogens and the results of most routine STTs are statistically dependent. We recommend the sequential testing program combining STTs and carclnogenicity assay, the optimal STT batteries, the rules of the sequential discrimination and the preferal choices of STTs tor specific chemical class. For illustrative pmposes the carclnogenicity prediction of several sample chamicals is presented. The results of cost-effectiveness analysis suggest that this program has vast social-economic effectiveness.展开更多
Computer supported collaborative design (CSCD) technology has been applied extensively with intensive market competition.The key technologies and problems of CSCD are analyzed and a CSCD design frame faced to product ...Computer supported collaborative design (CSCD) technology has been applied extensively with intensive market competition.The key technologies and problems of CSCD are analyzed and a CSCD design frame faced to product design is estab- lished.Then a CSCD system faced to radar key components is founded with Pro/INTRALINK software and re-exploiting technolo- gy.Some key processes are also designed,such as database management,work flow programming,information communication, file release,conflict identification and safety management.These will provide a reference for constructing a cooperative design en- vironment.展开更多
文摘In this paper our studies about the sequential testing program for predicting and identificating carcinogens, sequential discriminant method and cost- effectiveness analysis are summarized. The analysis of our database of carcinogeniclty and genotoxicity of chemicals demonstrates the uncertainty . of short- term tests ( STTs ) to predict carcinogens and the results of most routine STTs are statistically dependent. We recommend the sequential testing program combining STTs and carclnogenicity assay, the optimal STT batteries, the rules of the sequential discrimination and the preferal choices of STTs tor specific chemical class. For illustrative pmposes the carclnogenicity prediction of several sample chamicals is presented. The results of cost-effectiveness analysis suggest that this program has vast social-economic effectiveness.
基金Funded by Tackling Item of Minister of Science and Technology(2001BA201A56)
文摘Computer supported collaborative design (CSCD) technology has been applied extensively with intensive market competition.The key technologies and problems of CSCD are analyzed and a CSCD design frame faced to product design is estab- lished.Then a CSCD system faced to radar key components is founded with Pro/INTRALINK software and re-exploiting technolo- gy.Some key processes are also designed,such as database management,work flow programming,information communication, file release,conflict identification and safety management.These will provide a reference for constructing a cooperative design en- vironment.
