The purpose of this cross-sectional study was to investigate the importance of health vigilance in the prevention of cervical cancer. The sample consisted of 536 women. To identify which risk factors were associated w...The purpose of this cross-sectional study was to investigate the importance of health vigilance in the prevention of cervical cancer. The sample consisted of 536 women. To identify which risk factors were associated with cervical cancer or with an increase in the mortality rate of this kind of cancer, a logistic regression model was used. The Odds Ratios (OR) and their respective 95% confidence intervals were also calculated. Most of them were at the age of highest incidence of cervical cancer (21 - 59 years old), had an unstable conjugal situation, minimal educational level (78.7%), low income (58.3%), consumed alcoholic beverages (56.4%), had a history of smoking (57.0%) and possessed limited knowledge about the prevention. These results are discussed in terms of a predictive model for cervical cancer that considers the importance of public health vigilance in the screening and precocious diagnosis.展开更多
AIM To clarify risk based upon segment length, diagnostic histological findings, patient age and year of surveillance, duration of surveillance and gender.METHODS Patients registered with the United Kingdom Barrett...AIM To clarify risk based upon segment length, diagnostic histological findings, patient age and year of surveillance, duration of surveillance and gender.METHODS Patients registered with the United Kingdom Barrett's Oesophagus Registry from 9 United Kingdom centers were included. The outcome measures were(1) development of all grades of dysplasia;(2) development of high-grade of dysplasia or adenocarcinoma; and(3) development of adenocarcinoma. Prevalent cases and subjects with < 1 year of follow-up were excluded. The covariates examined were segment length, previous biopsy findings, age at surveillance, duration of surveillance, year of surveillance and gender.RESULTS One thousand and one hundred thirty six patients were included(total 6474 patient-years). Fifty-four patients developed adenocarcinoma(0.83% per annum), 70 developed high-grade dysplasia/adenocarcinoma(1.1% per annum) and 190 developed any grade of dysplasia(3.5% per annum). High grade dysplasia and adenocarcinoma increased with age and duration of surveillance. The risk of low-grade dysplasia development was not dependent on age at surveillance. Segment length and previous biopsy findings were also significant factors for development of dysplasia and adenocarcinoma.CONCLUSION The risk of development of low-grade dysplasia is independent of age at surveillance, but high-grade dysplasia and adenocarcinoma were more commonly found at older age. Segment length and previous biopsy findings are also markers of risk. This study did not demonstrate stabilisation of the metaplastic segment with prolonged surveillance.展开更多
Background: There has been a great interest in tracking health-related fitness across the United States. The NFL PLAY 60 FITNESSGRAM Partnership Project (NFL P60FGPP) is a large participatory research network that inv...Background: There has been a great interest in tracking health-related fitness across the United States. The NFL PLAY 60 FITNESSGRAM Partnership Project (NFL P60FGPP) is a large participatory research network that involves the surveillance of fitness among more than 1000 schools spread throughout the country. Fitness data are collected by school staff and therefore these data can vary in quality and representativeness. Therefore, careful screening procedures are needed to ensure that the data can reflect actual patterns in the schools. This study examined the impact of different data screening procedures on outcomes of aerobic fitness (AF) collected from the NFL P60FGPP. Methods: Data were compiled from 149,101 youth from 504 schools and were processed using the established age- and gender-specific AF FITNESSGRAM health-related standards. Data were subjected to three different screening procedures (based on grade size and boy-to-girl ratio per grade). Linear models were computed to obtain unadjusted and adjusted (for age, BMI-Z, and socio-economic status) estimates of % youth in the Healthy Fitness Zone (HFZ) in order to determine if, 1) there were differences in % in the HFZ and 2) if differences could be explained by changes in the representativeness of the sample due to the different data screening procedures. Results: Depending on the screening procedure used, the final sample ranged from 96,999 (no screening) to 46,572 youth (most stringent criteria). The proportion of youth achieving appropriate levels of AF ranged from 56% to 61% with unscreened data resulting in consistently lower percentages of youth achieving the standard (P < 0.05). Overall, these differences were not explained by possible changes in demographic characteristics as the result of applying different screening criteria. Conclusions: The findings demonstrate the importance of establishing appropriate screening procedures that maximize sample size while also ensuring generalizability of the findings.展开更多
People’s health is the basis for the progress of social civilization and an important symbol of national prosperity and national strength.Using the entropy method,spatial autocorrelation,spatio-temporal geographic we...People’s health is the basis for the progress of social civilization and an important symbol of national prosperity and national strength.Using the entropy method,spatial autocorrelation,spatio-temporal geographic weighted regression and other methods,we conducted a comprehensive evaluation of the high-quality development level of public health in Guizhou Province from 2011 to 2020 and an evolutionary analysis of the spatio-temporal divergence.The results revealed four key aspects of the state of public health in Guizhou Province.(1)The overall level of public health is constantly improving,but structural imbalance is prominent.(2)From the spatial dimension,the spatial differences in the level of public health have gradually moved from significant to a state of equilibrium.The northeastern cities were more strongly driven by the radiation of the peripheral cities,while this effect was weaker in the southwestern cities.From the time dimension,the spatial pattern shows a clear gradient,with a faster vertical growth rate.(3)The overall spatial correlation of the level of public health is weak,with more cold spots than hot spots,showing a distribution pattern of“strong in the northeast and weak in the southwest”.(4)The new rural cooperative medical care participation rate,(rural)per capita health expenditure,and the electronic health record creation rate have become the most important drivers affecting the high-quality development of public health in Guizhou Province.展开更多
文摘The purpose of this cross-sectional study was to investigate the importance of health vigilance in the prevention of cervical cancer. The sample consisted of 536 women. To identify which risk factors were associated with cervical cancer or with an increase in the mortality rate of this kind of cancer, a logistic regression model was used. The Odds Ratios (OR) and their respective 95% confidence intervals were also calculated. Most of them were at the age of highest incidence of cervical cancer (21 - 59 years old), had an unstable conjugal situation, minimal educational level (78.7%), low income (58.3%), consumed alcoholic beverages (56.4%), had a history of smoking (57.0%) and possessed limited knowledge about the prevention. These results are discussed in terms of a predictive model for cervical cancer that considers the importance of public health vigilance in the screening and precocious diagnosis.
基金Supported by The Barrett’s Oesophagus CampaignThe Wexham Gastrointestinal Trust+1 种基金The Childwick Trust,The R.L.St J.Harmsworth Memorial Research FundThe David and Frederick Barclay Foundation
文摘AIM To clarify risk based upon segment length, diagnostic histological findings, patient age and year of surveillance, duration of surveillance and gender.METHODS Patients registered with the United Kingdom Barrett's Oesophagus Registry from 9 United Kingdom centers were included. The outcome measures were(1) development of all grades of dysplasia;(2) development of high-grade of dysplasia or adenocarcinoma; and(3) development of adenocarcinoma. Prevalent cases and subjects with < 1 year of follow-up were excluded. The covariates examined were segment length, previous biopsy findings, age at surveillance, duration of surveillance, year of surveillance and gender.RESULTS One thousand and one hundred thirty six patients were included(total 6474 patient-years). Fifty-four patients developed adenocarcinoma(0.83% per annum), 70 developed high-grade dysplasia/adenocarcinoma(1.1% per annum) and 190 developed any grade of dysplasia(3.5% per annum). High grade dysplasia and adenocarcinoma increased with age and duration of surveillance. The risk of low-grade dysplasia development was not dependent on age at surveillance. Segment length and previous biopsy findings were also significant factors for development of dysplasia and adenocarcinoma.CONCLUSION The risk of development of low-grade dysplasia is independent of age at surveillance, but high-grade dysplasia and adenocarcinoma were more commonly found at older age. Segment length and previous biopsy findings are also markers of risk. This study did not demonstrate stabilisation of the metaplastic segment with prolonged surveillance.
文摘Background: There has been a great interest in tracking health-related fitness across the United States. The NFL PLAY 60 FITNESSGRAM Partnership Project (NFL P60FGPP) is a large participatory research network that involves the surveillance of fitness among more than 1000 schools spread throughout the country. Fitness data are collected by school staff and therefore these data can vary in quality and representativeness. Therefore, careful screening procedures are needed to ensure that the data can reflect actual patterns in the schools. This study examined the impact of different data screening procedures on outcomes of aerobic fitness (AF) collected from the NFL P60FGPP. Methods: Data were compiled from 149,101 youth from 504 schools and were processed using the established age- and gender-specific AF FITNESSGRAM health-related standards. Data were subjected to three different screening procedures (based on grade size and boy-to-girl ratio per grade). Linear models were computed to obtain unadjusted and adjusted (for age, BMI-Z, and socio-economic status) estimates of % youth in the Healthy Fitness Zone (HFZ) in order to determine if, 1) there were differences in % in the HFZ and 2) if differences could be explained by changes in the representativeness of the sample due to the different data screening procedures. Results: Depending on the screening procedure used, the final sample ranged from 96,999 (no screening) to 46,572 youth (most stringent criteria). The proportion of youth achieving appropriate levels of AF ranged from 56% to 61% with unscreened data resulting in consistently lower percentages of youth achieving the standard (P < 0.05). Overall, these differences were not explained by possible changes in demographic characteristics as the result of applying different screening criteria. Conclusions: The findings demonstrate the importance of establishing appropriate screening procedures that maximize sample size while also ensuring generalizability of the findings.
基金The Guizhou Science and Technology Foundation(ZK[2021]General 186)The National Natural Science Foundation of China(42271228,42101209)+1 种基金The Guizhou Provincial Department of Education Natural Science Research Fund(Guizhou Jiaohe KY Zi[2022]No.156)TheGuizhou Normal University Doctoral Research Project(GZNUD[2019]No.5).
文摘People’s health is the basis for the progress of social civilization and an important symbol of national prosperity and national strength.Using the entropy method,spatial autocorrelation,spatio-temporal geographic weighted regression and other methods,we conducted a comprehensive evaluation of the high-quality development level of public health in Guizhou Province from 2011 to 2020 and an evolutionary analysis of the spatio-temporal divergence.The results revealed four key aspects of the state of public health in Guizhou Province.(1)The overall level of public health is constantly improving,but structural imbalance is prominent.(2)From the spatial dimension,the spatial differences in the level of public health have gradually moved from significant to a state of equilibrium.The northeastern cities were more strongly driven by the radiation of the peripheral cities,while this effect was weaker in the southwestern cities.From the time dimension,the spatial pattern shows a clear gradient,with a faster vertical growth rate.(3)The overall spatial correlation of the level of public health is weak,with more cold spots than hot spots,showing a distribution pattern of“strong in the northeast and weak in the southwest”.(4)The new rural cooperative medical care participation rate,(rural)per capita health expenditure,and the electronic health record creation rate have become the most important drivers affecting the high-quality development of public health in Guizhou Province.
