期刊文献+
共找到19,364篇文章
< 1 2 250 >
每页显示 20 50 100
Parental Psychological Control and Internet Gaming Disorder Tendency:A Moderated Mediation Model of Core Self-Evaluation and Intentional Self-Regulation
1
作者 Zhiqiao Ji Shuhua Wei Hejuan Ding 《International Journal of Mental Health Promotion》 2024年第7期547-558,共12页
Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high... Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high school student population.The present study aimed to reveal the explanatory mechanisms underlying the association between parental psychological control(PPC)and internet gaming disorder tendency among junior high school students by testing the mediating role of core self-evaluation(CSE)and the moderating role of intentional self-regulation(ISR).Participants in present study were 735 Chinese junior high school students who completed offline self-report questionnaires on parental psychological control,core self-evaluation,intentional self-regulation,and Internet gaming disorder tendency.Analyses were conducted via mediation and moderated mediation.The results showed that:(1)Parental psychological control was positively related to junior high school students’Internet gaming disorder tendency.Core self-evaluation,and intentional self-regulation were negatively related to junior high school students’Internet gaming disorder tendency,respectively.(2)Core self-evaluation partially mediated the relationship between parental psychological control and junior high school students’Internet gaming disorder tendency.(3)Intentional self-regulation moderated the association between parental psychological control and Internet gaming disorder tendency,as well as the relationships between parental psychological control and core self-evaluation and core self-evaluation and Internet gaming disorder tendency in the mediated model.Based on these findings,we believe that there is a need to weaken parental psychological control,strengthen junior high school students’core self-evaluation and intentional self-regulation,and to recognize the important role of parents as well as their children’s personal positive traits in the healthy development of junior high school students. 展开更多
关键词 Internet gaming disorder tendency parental psychological control core self-evaluation intentional self-regulation moderated mediation model junior high school students
下载PDF
A Study on Rural Cultural Communication of Short Videos From the Perspective of Mediation-Taking the Popularization of “Village BA” (Village Basketball Association) in Qiandongnan as an Example
2
作者 SHEN Lei JIA Peng WEI Xiaojia 《Journalism and Mass Communication》 2024年第3期209-214,共6页
With the rise of new media and short videos shaping the new communication environment,rural culture has been mediated and transformed to spread to a wider region.As a cultural achievement of rural revitalization,“Vil... With the rise of new media and short videos shaping the new communication environment,rural culture has been mediated and transformed to spread to a wider region.As a cultural achievement of rural revitalization,“Village BA”(Village Basketball Association)demonstrates Chinese modernization.The use of short videos,mass rural movements,and“spectacle”spaces to attract spectators has become a key issue in the dissemination of rural culture. 展开更多
关键词 new media mediated rural culture short video “Village BA”
下载PDF
Bio-capped and green synthesis of ZnO/g-C_(3)N_(4) nanocomposites and its improved antibiotic and photocatalytic activities: An exceptional approach towards environmental remediation 被引量:2
3
作者 Iltaf Khan Chunjuan Wang +7 位作者 Shoaib Khan Jinyin Chen Aftab Khan Sayyar Ali Shah Aihua Yuan Sohail Khan Mehwish KButt Humaira Asghar 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第4期215-224,共10页
In this research study, we have synthesized the bio-capped ZnO/g-C_(3)N_(4) nanocomposites by employing lemon juice(Citrus limon) as a stabilizer and mediator. Fruitfully, lemon juice which contains various acidic fun... In this research study, we have synthesized the bio-capped ZnO/g-C_(3)N_(4) nanocomposites by employing lemon juice(Citrus limon) as a stabilizer and mediator. Fruitfully, lemon juice which contains various acidic functional groups and citric acid has the capability to block the surface of g-C_(3)N_(4) from chemical reactivity and activated the surface of g-C_(3)N_(4) for various reactions. Consequently, the agglomeration behavior and controlled shape of g-C_(3)N_(4) has also been achieved. Our experimental results i.e. XRD,TEM, HRTEM, PL, FS, XPS, and PEC have confirmed that the lemon juice mediated and green g-C_(3)N_(4)(L-CN) have good performances and remarkable visible light photocatalytic activities as compared to the chemically synthesized g-C_(3)N_(4)(CN). Furthermore, the small surface area and low charge separation of g-C_(3)N_(4) is upgraded by coupling with Zn O nanoparticles. It is proved that the coupling of Zn O worked as a facilitator and photoelectron modulator to enhance the charge separation of g-C_(3)N_(4). Compared to pristine lemon-mediated green g-C_(3)N_(4)(L-CN), the most active sample 5Zn O/L-CN showed ~ 5-fold improvement in activities for ciprofloxacin(CIP) and methylene blue(MB) degradation. More specifically,the mineralization process and degradation pathways, and the mineralization process of ciprofloxacin(CIP) and methylene blue(MB) are suggested. Finally, our present novel research work will provide new access to synthesize the eco-friendly and bio-caped green g-C_(3)N_(4)nanomaterials and their employment for pollutants degradation and environmental purification. 展开更多
关键词 Bio-caped green g-C_(3)N_(4) Lemon juice mediators ZnO/g-C_(3)N_(4)nanocomposite Environmental remediation Degradation pathways
下载PDF
Reflections on,and Improvements of,the Mediation Functions of People's Assessors
4
作者 Wang Gali 《Contemporary Social Sciences》 2023年第6期20-32,共13页
Legislatively,the people’s assessors are defined as individuals who share judicial power.However,in the context of dispute resolutions,their role is restricted by the courts,which affects the extent of their assessor... Legislatively,the people’s assessors are defined as individuals who share judicial power.However,in the context of dispute resolutions,their role is restricted by the courts,which affects the extent of their assessorial activities.It is imperative to reconsider the implications of the people’s assessors’deep involvement in mediation from the standpoint of societal division of labor.To enhance this division of labor,it is advisable that the people’s assessors relinquish their mediation roles.It is necessary to redefine the distinctions between people’s assessors,judges,and people’s mediators,including specially invited mediators.This would not only make up the deficiencies in the role of professional judges but also relieve the tension between judicial professionalism and popular accountability. 展开更多
关键词 social division of labor assessor system mediation function REFLECTION improvement
下载PDF
Mediation Effect of Employee Training on Implementation of Hotel Environmental Management Practices for Hotel Business Sustainability in Tanzania
5
作者 Naiman N.Mbise Perpetua Ishika 《Journal of Tourism and Hospitality Management》 2023年第2期60-86,共27页
The study assessed the mediation effect of employee training on implementation of hotel management practices for hotel business sustainability in Tanzania.Study was conducted in two cities Arusha and Dar es Salaam whe... The study assessed the mediation effect of employee training on implementation of hotel management practices for hotel business sustainability in Tanzania.Study was conducted in two cities Arusha and Dar es Salaam whereby a structured questionnaire with Likert scale range from one to five was used to collect information from the sample of 400 hotels’managers.The findings of the hypothesis indicate that two hypotheses were significant at significant at p<0.001 and one was not significant.The first hypothesis found that environmental management practice has positive effect on business sustainability highly significant at p<0.001.The second hypothesis was that there was positive relationship between environmental management practices and employee training at highly significant of p<0.001 and was accepted.Third hypothesis was that employee training has no mediation effect on the hotel business sustainability whereby p>0.05 hence rejected.It was also found the direct effect was significance at p<0.01 while indirect effect was not significance at p>0.05 and total effect was significance at p<0.01.It was concluded that,employees’training does not mediate the implementation of hotel environmental management practices for sustainability of hotel business in Tanzania. 展开更多
关键词 mediation employee training SUSTAINABILITY hotel business
下载PDF
The Social Surveillance and Generational Compliance in New Mediation
6
作者 Khamis Juma Abdalla 《Journalism and Mass Communication》 2023年第1期26-34,共9页
This article explores the social transformation on account of surveillance conception preoccupied through the technology diffusion thanks to the Web 2.0 novel features.The new mediation abstracts the social provisions... This article explores the social transformation on account of surveillance conception preoccupied through the technology diffusion thanks to the Web 2.0 novel features.The new mediation abstracts the social provisions into radical customs of surveillance.It primes the supposition of socialization hitherto to transpire the scrutiny of the mutual rehearses of vertical and horizontal surveillance.Hence,the ultimate conversion keeps on through self-exposition notion in views of social interaction which so far posit the question of the privacy and public boundary owing to the hypothetical undue freedom of self-expression through Web 2.0.Thus,this paper examines the Surveillance Society in a comprehensive scope of the social structure vis-à-vis the ideas of generational submission towards social transformation.Using the dichotomy of digital revolutions,the Digital“Natives”are classified as typically addicted digital consumptions bearing the community outlooks,while Digital“Immigrants”persist in semi obedience along with the traditional adherence.Ultimately,the Panopticon conceptualizes the certainty of social surveillance by dint of proliferation of information flows keen on social conducts automated in both online and offline paths through technological appliances. 展开更多
关键词 generational divide new mediation self-expression and exposition social transformation Surveillance Society Web 2.0
下载PDF
METTL7A-mediated m6A modification of corin reverses bisphosphonates-impaired osteogenic differentiation of orofacial BMSCs
7
作者 Yizhou Jin Xiao Han +1 位作者 Yuejun Wang Zhipeng Fan 《International Journal of Oral Science》 SCIE CAS CSCD 2024年第3期528-538,共11页
Bisphosphonate-related osteonecrosis of jaw(BRONJ)is characterized by impaired osteogenic differentiation of orofacial bone marrow stromal cells(BMSCs).Corin has recently been demonstrated to act as a key regulator in... Bisphosphonate-related osteonecrosis of jaw(BRONJ)is characterized by impaired osteogenic differentiation of orofacial bone marrow stromal cells(BMSCs).Corin has recently been demonstrated to act as a key regulator in bone development and orthopedic disorders.However,the role of corin in BRONJ-related BMSCs dysfunction remains unclarified.A m6A epitranscriptomic microarray study from our group shows that the CORIN gene is significantly upregulated and m6A hypermethylated during orofacial BMSCs osteogenic differentiation.Corin knockdown inhibits BMSCs osteogenic differentiation,whereas corin overexpression or soluble corin(sCorin)exerts a promotion effect.Furthermore,corin expression is negatively regulated by bisphosphonates(BPs).Corin overexpression or sCorin reverses BPs-impaired BMSCs differentiation ability.Mechanistically,we find altered expression of phos-ERK in corin knockdown/overexpression BMSCs and BMSCs under sCorin stimulation.PD98059(a selective ERK inhibitor)blocks the corin-mediated promotion effect.With regard to the high methylation level of corin during osteogenic differentiation,we apply a non-selective m6A methylase inhibitor,Cycloleucine,which also blocks the corin-mediated promotion effect.Furthermore,we demonstrate that METTL7A modulates corin m6A modification and reverses BPs-impaired BMSCs function,indicating that METTL7A regulates corin expression and thus contributes to orofacial BMSCs differentiation ability.To conclude,our study reveals that corin reverses BPs-induced BMSCs dysfunction,and METTL7A-mediated corin m6A modification underlies corin promotion of osteogenic differentiation via the ERK pathway.We hope this brings new insights into future clinical treatments for BRONJ. 展开更多
关键词 IMPAIRED cor mediated
下载PDF
Heterostructured nickel-cobalt metal alloy and metal oxide nanoparticles as a polysulfide mediator for stable lithium-sulfur full batteries with lean electrolyte
8
作者 Hyeona Park Suyeong Lee +6 位作者 Hyerim Kim Hyunyoung Park Hun Kim Jongsoon Kim Marco Agostini Yang-Kook Sun Jang-Yeon Hwang 《Carbon Energy》 SCIE EI CAS CSCD 2024年第7期163-177,共15页
Batteries that utilize low-cost elemental sulfur and light metallic lithium as electrodes have great potential in achieving high energy density.However,building a lithium-sulfur(Li-S)full battery by controlling the el... Batteries that utilize low-cost elemental sulfur and light metallic lithium as electrodes have great potential in achieving high energy density.However,building a lithium-sulfur(Li-S)full battery by controlling the electrolyte volume generally produces low practical energy because of the limited electrochemical Li-S redox.Herein,the high energy/high performance of a Li-S full battery with practical sulfur loading and minimum electrolyte volume is reported.A unique hybrid architecture configured with Ni-Co metal alloy(NiCo)and metal oxide(NiCoO_(2))nanoparticles heterogeneously anchored in carbon nanotube-embedded selfstanding carbon matrix is fabricated as a host for sulfur.This work demonstrates the considerable improvement that the hybrid structure's high conductivity and satisfactory porosity promote the transport of electrons and lithium ions in Li-S batteries.Through experimental and theoretical validations,the function of NiCo and NiCoO_(2) nanoparticles as an efficient polysulfide mediator is established.These particles afford polysulfide anchoring and catalytic sites for Li-S redox reaction,thus improving the redox conversion reversibility.Even at high sulfur loading,the nanostructured Ni-Co metal alloy and metal oxide enable to have stable cycling performance under lean electrolyte conditions both in half-cell and full-cell batteries using a graphite anode. 展开更多
关键词 full cell high energy lean electrolyte Li-S batteries polysulfide mediator
下载PDF
Linear paired electrolysis of furfural to furoic acid at both anode and cathode in a multiple redox mediated system
9
作者 Xinxin Li Linchuan Cong +4 位作者 Haibo Lin Fangbing Liu Xiangxue Fu Hai-Chao Xu Nan Lin 《Green Energy & Environment》 SCIE EI CAS CSCD 2024年第1期104-113,共10页
Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we r... Implementing a new energy-saving electrochemical synthesis system with high commercial value is a strategy of the sustainable development for upgrading the bulk chemicals preparation technology in the future.Here,we report a multiple redox-mediated linear paired electrolysis system,combining the hydrogen peroxide mediated cathode process with the I2 mediated anode process,and realize the conversion of furfural to furoic acid in both side of the dividedflow cell simultaneously.By reasonably controlling the cathode potential,the undesired water splitting reaction and furfural reduction side reactions are avoided.Under the galvanostatic electrolysis,the two-mediated electrode processes have good compatibility,which reduce the energy consumption by about 22%while improving the electronic efficiency by about 125%.This system provides a green electrochemical synthesis route with commercial prospects. 展开更多
关键词 Multiple redox mediated system Linear paired electrolysis FURFURAL Furoic acid
下载PDF
Causal association of obesity-related anthropometric traits with myopia and the mediating role of educational attainment:a Mendelian randomization study
10
作者 Yi Lu Can-Can Zhang +4 位作者 Run-Ting Ma Yuan-Jing Li Wen-Ping Li Die-Wen-Jie Hu Lian-Hong Zhou 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第11期2082-2092,共11页
AIM:To study the causal relationship between obesityrelated anthropometric traits and myopia and the mediating role of educational attainment(EA).METHODS:Univariable Mendelian randomization(UVMR)was performed to evalu... AIM:To study the causal relationship between obesityrelated anthropometric traits and myopia and the mediating role of educational attainment(EA).METHODS:Univariable Mendelian randomization(UVMR)was performed to evaluate the causal association between body mass index(BMI),height,waist-hip ratio(WHR,adjusted for BMI),and mean spherical equivalent(MSE).BMI was divided into fat and fat-free mass and included in multivariable Mendelian randomization(MVMR)to explore the roles of different BMI components in the causal relationship between BMI and MSE.A mediation analysis based on two-step Mendelian randomization(MR)was carried out.Specifically,UVMR was conducted to estimate the causal effect of BMI on EA.The direct effect of EA on MSE was estimated from MVMR.The mediation effect of EA in the BMI-EA-MSE model was calculated by the product of coefficients method.Expression quantitative trait loci(eQTL)-MR,reverse MR,and Linkage Disequilibrium Score Regression(LDSC)were performed to assess the robustness.RESULTS:Genetically predicted higher BMI had a positive total effect on MSE(βIVW=0.26 D,95%CI=0.14 to 0.37 D,P<0.001),whereas there was no significant association between height,WHR,and MSE.Fat mass was found to play a significant role in the effect of body mass on MSE(βIVW=0.50 D,95%CI=0.21 to 0.78 D,P=0.001),but there was no significant association between fat-free mass and MSE.The causal effect of BMI on EA was-0.14(95%CI=-0.16 to-0.11,P<0.001),and the direct effect of EA on MSE was-0.63 D(95%CI=-0.81 to-0.44 D,P<0.001).The mediating effect of EA in the BMI-EA-MSE model was 0.09 D(95%CI=0.06 to 0.12 D),with a mediation proportion of 33%(95%CI=22.1%to 44.6%).No reverse causal associations were detected except for BMI on EA.The results of eQTL-MR and LDSC were consistent with each MR analysis.CONCLUSION:Genetically predicted higher BMI decreases the degree of myopia with a 33%mediation proportion by EA,and fat mass provides a dominant protective role in body mass-myopia.As a supplement to previous observational studies,it provides strong evidence for the relationship between anthropometric traits and refractive errors and offers a theoretical basis for future measures to prevent and control myopia. 展开更多
关键词 MYOPIA anthropometric traits educational attainment mediation analysis Mendelian randomization
下载PDF
Pro-resolving lipid mediator reduces amyloid-β42–induced gene expression in human monocyte–derived microglia
11
作者 Ying Wang Xiang Zhang +6 位作者 Henrik Biverstål Nicolas GBazan Shuai Tan Nailin Li Makiko Ohshima Marianne Schultzberg Xiaofei Li 《Neural Regeneration Research》 SCIE CAS 2025年第3期873-886,共14页
Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment o... Specialized pro-resolving lipid mediators including maresin 1 mediate resolution but the levels of these are reduced in Alzheimer's disease brain, suggesting that they constitute a novel target for the treatment of Alzheimer's disease to prevent/stop inflammation and combat disease pathology. Therefore, it is important to clarify whether they counteract the expression of genes and proteins induced by amyloid-β. With this objective, we analyzed the relevance of human monocyte–derived microglia for in vitro modeling of neuroinflammation and its resolution in the context of Alzheimer's disease and investigated the pro-resolving bioactivity of maresin 1 on amyloid-β42–induced Alzheimer's disease–like inflammation. Analysis of RNA-sequencing data and secreted proteins in supernatants from the monocyte-derived microglia showed that the monocyte-derived microglia resembled Alzheimer's disease–like neuroinflammation in human brain microglia after incubation with amyloid-β42. Maresin 1 restored homeostasis by down-regulating inflammatory pathway related gene expression induced by amyloid-β42 in monocyte-derived microglia, protection of maresin 1 against the effects of amyloid-β42 is mediated by a re-balancing of inflammatory transcriptional networks in which modulation of gene transcription in the nuclear factor-kappa B pathway plays a major part. We pinpointed molecular targets that are associated with both neuroinflammation in Alzheimer's disease and therapeutic targets by maresin 1. In conclusion, monocyte-derived microglia represent a relevant in vitro microglial model for studies on Alzheimer's disease-like inflammation and drug response for individual patients. Maresin 1 ameliorates amyloid-β42–induced changes in several genes of importance in Alzheimer's disease, highlighting its potential as a therapeutic target for Alzheimer's disease. 展开更多
关键词 Alzheimer's disease amyloid-β maresin MICROGLIA MONOCYTE NEUROINFLAMMATION resolution RNA-sequencing specialized pro-resolving lipid mediator
下载PDF
Interoception mediates the association between social support and sociability in patients with major depressive disorder
12
作者 Wen-Liang Wang Ji-Kang Liu +6 位作者 Yi-Fan Sun Xiao-Hong Liu Yu-Hang Ma Xue-Zheng Gao Li-Min Chen Zhen-He Zhou Hong-Liang Zhou 《World Journal of Psychiatry》 SCIE 2024年第10期1484-1494,共11页
BACKGROUND Interoception dysfunction has an important impact on the onset and development of major depressive disorder(MDD).Social support serves as a protective factor against MDD,and sociability also plays a signifi... BACKGROUND Interoception dysfunction has an important impact on the onset and development of major depressive disorder(MDD).Social support serves as a protective factor against MDD,and sociability also plays a significant role in this condition.These interconnected constructs-social support and sociability-play pivotal roles in MDD.However,no research on the mechanisms underlying the associations be-tween social support and sociability,particularly the potential role of interocep-tion,have been reported.ception,social support,and sociability,respectively.A mediation analysis model for the eight dimensions of intero-ception(noticing,not distracting,not worrying,attention regulation,emotional awareness,self-regulation,body listening,and trust),social support,and sociability were established to evaluate the mediating effects.RESULTS A partial correlation analysis of eight dimensions of the MAIA-2,SSRS,and TSBI scores,with demographic data as control variables,revealed pairwise correlations between the SSRS score and both the MAIA-2 score and TSBI score.In the major depression(MD)group,the SSRS score had a positive direct effect on the TSBI score,while the scores for body listening,emotional awareness,self-regulation,and trust in the MAIA-2C had indirect effects on the TSBI score.In the HC group,the SSRS score had a positive direct effect on the TSBI score,and the scores for attention regulation,emotional awareness,self-regulation,and trust in the MAIA-2C had indirect effects on the TSBI score.The proportion of mediators in the MD group was lower than that in the HC group.CONCLUSION Interoceptive awareness is a mediating factor in the association between social support and sociability in both HCs and depressed patients.Training in interoceptive awareness might not only help improve emotional regulation in depressed patients but also enhance their social skills and support networks. 展开更多
关键词 INTEROCEPTION Social support SOCIABILITY Major depression mediation analysis
下载PDF
Scarcity and Mental Health—Multiple Mediators of Sleep Quality and Life Satisfaction
13
作者 Na Liu Yan Zhang Junxiu Wang 《International Journal of Mental Health Promotion》 2024年第6期449-462,共14页
Background:In the current social environment,scarcity,as a universally present objective state,profoundly impacts individuals’decision-making and health through the subjective feeling it induces,known as a“scarcity ... Background:In the current social environment,scarcity,as a universally present objective state,profoundly impacts individuals’decision-making and health through the subjective feeling it induces,known as a“scarcity mindset.”Particularly,the feeling of scarcity related to money and sleep time is not only widespread but also directly linked to an individual’s mental health.Purpose:This study aims to delve into the relationship between the feeling of scarcity and mental health,with a specific focus on the relationship between the feeling of money scarcity or sleep time scarcity and mental health,as well as the role of sleep quality or life satisfaction in this relationship.Procedure:We determined the sampling quotas based on the population and economic development levels of each province in the“China Statistical Yearbook(2021)”(National Bureau of Statistics,2021).Participants were selected using the Probability Proportional to Size(PPS)sampling method.Data was collected by distributing online questionnaires to participants,and the relationships between the main variables were explored using structural equation modeling.Results:1.In China,the feeling of sleep time scarcity is stronger than the feeling of money scarcity among the public.2.The feeling of money scarcity is positively correlated with depression and anxiety,whereas the feeling of sleep time scarcity is only positively correlated with depression.3.The feeling of scarcity mainly leads to depression and self-denial through reducing life satisfaction,and it leads to anxiety through reducing sleep quality.Conclusion:The feeling of scarcity in money and sleep time is related to different dimensions of mental health.Therefore,reasonably planning financial allocation and ensuring an adequate amount of sleep can reduce the sense of scarcity,thereby improving mental health.Additionally,improving sleep quality and increasing life satisfaction can alleviate the adverse effects of scarcity on mental health. 展开更多
关键词 SCARCITY sleep quality life satisfaction mental health multiple mediators
下载PDF
Resilience provides mediating effect of resilience between fear of progression and sleep quality in patients with hematological malignancies
14
作者 Yuan Tian Ying-Li Wang 《World Journal of Psychiatry》 SCIE 2024年第4期541-552,共12页
BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health bec... BACKGROUND Hematological tumors are common malignant tumors,with high morbidity and mortality rates.Most patients with hematological malignancies develop sleep disorders that seriously affect their life and health because of acute onset of disease,rapid progression,high recurrence rates,complex treatment methods,and treatment costs.AIM To explore the mediating effect of resilience on fear of disease progression and sleep quality in patients with hematological malignancies.METHODS A cross-sectional analysis of 100 patients with hematological malignancies,treated in the First Affiliated Hospital of Jinzhou Medical University between August 2022 and August 2023,was conducted.Patients were assessed using a general data survey,a simplified scale for the fear of progression(FoP)of disease,a resilience scale,and the Pittsburgh Sleep Quality Index.Statistical analysis was conducted to determine the relationship between various patient characteristics and FoP,resilience,and sleep quality.Spearman’s correlation analysis was used to examine the correlations between mental resilience,FoP,and sleep quality.RESULTS The total FoP score mean value in patients with hematological malignancies was 38.09±5.16;the total resilience score mean value was 40.73±7.04;and the Pittsburgh Sleep Quality Index score mean value was 10.72±1.90.FoP,resilience,and sleep quality of the patients were associated with family per capita monthly income and patient education level(P<0.05).Spearman correlation analysis revealed that FoP was negatively correlated with resilience and sleep quality scores(r=-0.560,-0.537,P<0.01),respectively,and resilience was significantly associated with sleep quality scores(r=0.688,P<0.01).Mediation analysis showed that the mediating effect of resilience between FoP and sleep quality in patients with hematological malignancies was-0.100 and accounted for 50.51%of the total effect.This indicated that FoP directly and indirectly affected sleep quality through the mesomeric effect of resilience.CONCLUSION Resilience is an intermediary variable between FoP and sleep quality in patients with hematological malignancies.Medical staff should evaluate and follow-up FoP and resilience to implement measures to improve sleep quality. 展开更多
关键词 RESILIENCE Blood tumor Fear of progression Sleep quality mediating effect
下载PDF
Association of education with cholelithiasis and mediating effects of cardiometabolic factors:A Mendelian randomization study
15
作者 Chang-Lei Li Yu-Kun Liu +1 位作者 Ying-Ying Lan Zu-Sen Wang 《World Journal of Clinical Cases》 SCIE 2024年第20期4272-4288,共17页
BACKGROUND Education,cognition,and intelligence are associated with cholelithiasis occurrence,yet which one has a prominent effect on cholelithiasis and which cardiometabolic risk factors mediate the causal relationsh... BACKGROUND Education,cognition,and intelligence are associated with cholelithiasis occurrence,yet which one has a prominent effect on cholelithiasis and which cardiometabolic risk factors mediate the causal relationship remain unelucidated.AIM To explore the causal associations between education,cognition,and intelligence and cholelithiasis,and the cardiometabolic risk factors that mediate the associations.METHODS Applying genome-wide association study summary statistics of primarily European individuals,we utilized two-sample multivariable Mendelian randomization to estimate the independent effects of education,intelligence,and cognition on cholelithiasis and cholecystitis(FinnGen study,37041 and 11632 patients,respectively;n=486484 participants)and performed two-step Mendelian randomization to evaluate 21 potential mediators and their mediating effects on the relationships between each exposure and cholelithiasis.RESULTS Inverse variance weighted Mendelian randomization results from the FinnGen consortium showed that genetically higher education,cognition,or intelligence were not independently associated with cholelithiasis and cholecystitis;when adjusted for cholelithiasis,higher education still presented an inverse effect on cholecystitis[odds ratio:0.292(95%CI:0.171-0.501)],which could not be induced by cognition or intelligence.Five out of 21 cardiometabolic risk factors were perceived as mediators of the association between education and cholelithiasis,including body mass index(20.84%),body fat percentage(40.3%),waist circumference(44.4%),waist-to-hip ratio(32.9%),and time spent watching television(41.6%),while time spent watching television was also a mediator from cognition(20.4%)and intelligence to cholelithiasis(28.4%).All results were robust to sensitivity analyses.CONCLUSION Education,cognition,and intelligence all play crucial roles in the development of cholelithiasis,and several cardiometabolic mediators have been identified for prevention of cholelithiasis due to defects in each exposure. 展开更多
关键词 CHOLELITHIASIS Mendelian randomization mediation analysis Education attainment Cardiometabolic risk factors COGNITION INTELLIGENCE
下载PDF
Mediating role of social support in dysphoria,despondency,and quality of life in patients undergoing maintenance hemodialysis
16
作者 Xiang Zhou Hong Jiang +4 位作者 Yi-Peng Zhou Xiao-Yu Wang Hai-Yan Ren Xue-Fei Tian Qing-Qing Zhang 《World Journal of Psychiatry》 SCIE 2024年第3期409-420,共12页
BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing Maintenance Hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can signif... BACKGROUND Dysphoria and despondency are prevalent psychological issues in patients undergoing Maintenance Hemodialysis(MHD)that significantly affect their quality of life(QOL).High levels of social support can significantly improve the physical and mental well-being of patients undergoing MHD.Currently,there is limited research on how social support mediates the relationship between dysphoria,despondency,and overall QOL in patients undergoing MHD.It is imperative to investigate this mediating effect to mitigate dysphoria and despondency in patients undergoing MHD,ultimately enhancing their overall QOL.AIM To investigate the mediating role of social support in relationships between dysphoria,despondency,and QOL among patients undergoing MHD.METHODS Participants comprised 289 patients undergoing MHD,who were selected using a random sampling approach.The Social Support Rating Scale,Self-Rating Anxiety Scale,Self-Rating Depression Scale,and QOL Scale were administered.Correlation analysis was performed to examine the associations between social support,dysphoria,despondency,and QOL in patients undergoing MHD.To assess the mediating impact of social support on dysphoria,despondency,and QOL in patients undergoing MHD,a bootstrap method was applied.RESULTS Significant correlations among social support,dysphoria,despondency,and quality in patients undergoing MHD were observed(all P<0.01).Dysphoria and despondency negatively correlated with social support and QOL(P<0.01).Dysphoria and despondency had negative predictive impacts on the QOL of patients undergoing MHD(P<0.05).The direct effect of dysphoria on QOL was statistically significant(P<0.05).Social support mediated the relationship between dysphoria and QOL,and this mediating effect was significant(P<0.05).Similarly,the direct effect of despondency on QOL was significant(P<0.05).Moreover,social support played a mediating role between despondency and QOL,with a significant mediating effect(P<0.05).CONCLUSION These findings suggest that social support plays a significant mediating role in the relationship between dysphoria,despondency,and QOL in patients undergoing MHD. 展开更多
关键词 Maintenance hemodialysis Social support DYSPHORIA Despondency Quality of life mediating effect
下载PDF
The Influence of Academic Self-Efficacy on Learning Engagement in Online Education in China:The Mediating Role of Effort
17
作者 Yan Zhang Zhicui Yao Jian Wang 《Journal of Contemporary Educational Research》 2024年第10期61-68,共8页
The shift towards online intelligent learning has become the norm in education and is now a fundamental part of modern educational activities.However,this new model can influence students’learning behavior and lead t... The shift towards online intelligent learning has become the norm in education and is now a fundamental part of modern educational activities.However,this new model can influence students’learning behavior and lead to changes in their approach to learning.Based on online intelligent learning,we investigated how the academic self-efficacy of nursing students affects their engagement with learning and explored the role of academic attribution as a mediator.Five hundred fifty-three nursing college students from Hebei and Hunan provinces in China participated in the online questionnaire.The results revealed that effort plays a mediating role in the relationship between academic self-efficacy and learning engagement. 展开更多
关键词 Academic self-efficacy Learning engagement Online learning mediating role EFFORT
下载PDF
Dynamic Non-Invasive Detection of NADH Based on Blood Flow-Mediated Skin Fluorescence (FMSF) Method
18
作者 Peng Liu Tengfei Bi +2 位作者 Gongzhi Du Long Yan Huayi Hou 《Open Journal of Applied Sciences》 2024年第6期1437-1453,共17页
Nicotinamide adenine dinucleotide (NADH/NAD+) is involved in important biochemical reactions in human metabolism, including participation in energy production by mitochondria. The changes in fluorescence intensity as ... Nicotinamide adenine dinucleotide (NADH/NAD+) is involved in important biochemical reactions in human metabolism, including participation in energy production by mitochondria. The changes in fluorescence intensity as a function of time in response to blocking and releasing of blood flow in a forearm are used as a measure of oxygen transport with blood to the tissue, which directly correlates with the skin microcirculation status. In this paper, a non-invasive dynamic monitoring system based on blood flow-mediated skin fluorescence (FMSF) technology is developed to monitor the NADH fluorescence intensity of skin tissue during the process of blocking reactive hyperemia. Simultaneously, laser speckle contrast imaging (LSCI) and laser Doppler flowmetry (LDF) were used to observe blood flow, blood oxygen saturation (SOt2) and relative amount of hemoglobin (rHb) during the measurement process, which helped to explore NADH dynamics relevant physiological changes. A variety of parameters have been derived to describe NADH fluorescence curve based on the FMSF device. The experimental results are conducive to understanding the NADH measurement and the physiological processes related to it, which help FMSF to be a great avenue for in vivo physiological, clinical and pharmacological research on mitochondrial metabolism. 展开更多
关键词 Reduced Nicotinamide Adenine Dinucleotide (NADH) Flow-mediated Skin Fluorescence (FMSF) Laser Doppler Flowmetry (LDF) Blood Flow
下载PDF
基于Mediation的异构数据集成系统HDIS设计与实现 被引量:15
19
作者 袁晓洁 于士涛 李志梁 《计算机工程与应用》 CSCD 北大核心 2006年第1期162-165,221,共5页
采用Mediator/Wrapper方式集成分布式异构数据是当今数据库领域的研究热点。论文在分析国外现有产品的基础上,提出了一个基于Mediation的异构数据集成解决方案,并针对该方案设计实现了一个异构数据集成系统HDIS(HeterogeneousDataIntegr... 采用Mediator/Wrapper方式集成分布式异构数据是当今数据库领域的研究热点。论文在分析国外现有产品的基础上,提出了一个基于Mediation的异构数据集成解决方案,并针对该方案设计实现了一个异构数据集成系统HDIS(HeterogeneousDataIntegrationSystem)。该文主要介绍HDIS的整体架构和实现过程中的关键技术。 展开更多
关键词 异构数据集成 中介器 包装器 框架
下载PDF
On legal value of mediation——from the view of jurisprudence
20
作者 陈娟 《科教文汇》 2007年第1期120-120,共1页
Mediation is becoming more and more important in the process of settling conflict nowadays,so it’s quite necessary to explain the legal value of mediation from the view of jurisprudence.
关键词 mediation value of law justice
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部