OBJECTIVE To study the clinical and histopathological characteristics of pulmonary blastoma(PB),and to review the diagnostic criterion and treatment methods.METHODS Clinical and histopathological data from 15 cases of...OBJECTIVE To study the clinical and histopathological characteristics of pulmonary blastoma(PB),and to review the diagnostic criterion and treatment methods.METHODS Clinical and histopathological data from 15 cases of PB in this hospital,from 1990 to 2006,were retrospectively analyzed.RESULTS Surgical procedures were conducted in all 15 patients,including pulmonary lobectomy in 9,lobectomy of the 2 right pulmonary lobes in 2,excision of pulmonary segments in 1,lobectomy and bronchoplasty in 1,lobectomy and angioplasty in 1,and excision of the whole left lung in 1.Of the 15 cases,11 were misdiagnosed as lung cancer,2 were doubted to be a benign tumor before surgery,1 was suspected to be a malignant mesenchymoma,and only 1 was diagnosed as a PB.CONCLUSION Preoperative final diagnosis of PB is very difficult,since the clinical symptoms of the disease are nonspecific.To confirm the diagnosis,comprehensive consideration of the factors,such as the clinical manifestations,morphological characteristics and immunohistochemical tumor markers,should be taken.Surgery is the treatment of choice for PB,and a thorough removal is the key to a cure.PB has a high malignancy and o en recurs and metastasizes,usually with a poor prognosis.展开更多
Pulmonary blastoma （PB） is a relatively rare intrathoracic neoplasm that is composed of immature malignant epithelial and/or mesenchymal tissues whose features may resemble early embryological lung tissues . They ha...Pulmonary blastoma （PB） is a relatively rare intrathoracic neoplasm that is composed of immature malignant epithelial and/or mesenchymal tissues whose features may resemble early embryological lung tissues . They have been divided into three subgroups - classic biphasic pulmonary blastoma （BPB）, well-differentiated fetal ad enocarcinoma （WDFA） and pleuropulmonary blastoma （PPB） , among which BPB is the most common subtype and its prognosis is fairly poor, especially in case of accompanying local infiltration or distant metastasis. There have been several case reports about BPB with distant metastasis to brain, lung, kidney, even to pancrea. Here we reported a case of biphasic pulmonary blastoma with metastasis to adjacent rib.展开更多
基金the Hebei Provincial Fund for Development of Oncology Faculty,based on High Scholarship and Creative Research Potential (No.[2005]52)
文摘OBJECTIVE To study the clinical and histopathological characteristics of pulmonary blastoma(PB),and to review the diagnostic criterion and treatment methods.METHODS Clinical and histopathological data from 15 cases of PB in this hospital,from 1990 to 2006,were retrospectively analyzed.RESULTS Surgical procedures were conducted in all 15 patients,including pulmonary lobectomy in 9,lobectomy of the 2 right pulmonary lobes in 2,excision of pulmonary segments in 1,lobectomy and bronchoplasty in 1,lobectomy and angioplasty in 1,and excision of the whole left lung in 1.Of the 15 cases,11 were misdiagnosed as lung cancer,2 were doubted to be a benign tumor before surgery,1 was suspected to be a malignant mesenchymoma,and only 1 was diagnosed as a PB.CONCLUSION Preoperative final diagnosis of PB is very difficult,since the clinical symptoms of the disease are nonspecific.To confirm the diagnosis,comprehensive consideration of the factors,such as the clinical manifestations,morphological characteristics and immunohistochemical tumor markers,should be taken.Surgery is the treatment of choice for PB,and a thorough removal is the key to a cure.PB has a high malignancy and o en recurs and metastasizes,usually with a poor prognosis.
文摘Pulmonary blastoma （PB） is a relatively rare intrathoracic neoplasm that is composed of immature malignant epithelial and/or mesenchymal tissues whose features may resemble early embryological lung tissues . They have been divided into three subgroups - classic biphasic pulmonary blastoma （BPB）, well-differentiated fetal ad enocarcinoma （WDFA） and pleuropulmonary blastoma （PPB） , among which BPB is the most common subtype and its prognosis is fairly poor, especially in case of accompanying local infiltration or distant metastasis. There have been several case reports about BPB with distant metastasis to brain, lung, kidney, even to pancrea. Here we reported a case of biphasic pulmonary blastoma with metastasis to adjacent rib.
