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Exploring the therapeutic potential of Qi Teng Mai Ning recipe in ischemic stroke and vascular cognitive impairment
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作者 Jia-Yan Yao Yue-Lan Yang +1 位作者 Wei-Jian Chen Hai-Ying Fan 《Traditional Medicine Research》 2024年第10期21-35,共15页
Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on id... Background:This study aims to explore the therapeutic effects of the Qi Teng Mai Ning recipe on ischemic stroke and vascular cognitive impairment through its potential to modulate cellular autophagy,with a focus on identifying its active ingredients and their target proteins.Methods:The study began with the identification of active ingredients in the Qi Teng Mai Ning recipe.It proceeded to screen the gene expression omnibus database for ischemic stroke and vascular cognitive impairment-associated differentially expressed mRNAs and to identify cellular autophagy-related proteins via the Human Autophagy Database.These proteins were annotated with Gene Ontology and Kyoto Encyclopedia of Genes and Genomes functions and subjected to molecular docking with the recipe’s core active ingredients.In vitro cell experiments were conducted on hypoxic HT22 cells,involving CCK8 assay,lentiviral transfection to silence autophagy related 9B(ATG9B),immunofluorescence staining,and qPCR validation to investigate the effects of the recipe on autophagy.Results:The analysis identified 104 active ingredients targeting 408 proteins and forming a complex ingredient-target network.Intersecting 55 ischemic stroke-related and 909 vascular cognitive impairment-related differentially expressed mRNAs revealed 14 co-expressed mRNAs.Molecular docking showed quercetin,kaempferol,myrcene,and conferone as key ingredients targeting autophagy-related proteins.Cellular experiments indicated that the recipe significantly enhanced cell viability under hypoxic conditions,reduced apoptosis,and modulated the expression of autophagy-related factors,thereby decreasing apoptosis rates in HT22 cells.Conclusion:The Qi Teng Mai Ning recipe offers protective effects against ischemic stroke and vascular cognitive impairment by modulating autophagy-related proteins.Its efficacy highlights the potential of traditional Chinese medicine in treating these conditions,though further research is needed to fully understand its mechanisms and clinical applications. 展开更多
关键词 qi Teng Mai Ning recipe AUTOPHAGY ischemic stroke vascular cognitive impairment traditional Chinese medicine
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The Essential Role of Zheng Qi in Promoting Health: From the Perspective of Chinese Medicine and Modern Medicine
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作者 Kam Ming Ko Hoi Yan Leung 《Chinese Medicine》 CAS 2024年第2期27-33,共7页
The concept of Zheng Qi in traditional Chinese medicine (TCM) refers to the vital energy produced by the interaction of Yin and Yang forces in the body. Zheng Qi performs two main functions: Wei Qi (defensive Qi), whi... The concept of Zheng Qi in traditional Chinese medicine (TCM) refers to the vital energy produced by the interaction of Yin and Yang forces in the body. Zheng Qi performs two main functions: Wei Qi (defensive Qi), which shields the body from external pathogens, and Ying Qi (nutritive Qi), which sustains the internal organs and enhances their functionality. In TCM, Chinese tonifying herbs can help restore the balance of Yin/Yang and Qi/Blood function in visceral organs (i.e., optimal physiological functions), thereby fostering the efficient production of Zheng Qi and enhancing health. To ensure the quality of Chinese herbal products, functional assays to measure Yin/Yang, Qi/Blood functions, and Zheng Qi production should be implemented. The efficacy of Yang and Qi herbs can be evaluated by their ability to increase mitochondrial ATP in cultured mouse cardiomyocytes, while Yin and Blood herbs are tested through their immunostimulatory effects on antigen-induced T/B cell proliferation in mouse splenocytes and the production of erythropoietin/nitric oxide in hepatocytes/vascular endothelial cells, respectively. Additionally, Zheng Qi’s effect can be gauged by examining natural killer cell activity and antigen-induced T/B cell proliferation in mice ex vivo. These assays act as biomarkers for assessing the quality and effectiveness of herbal health products within TCM theory. 展开更多
关键词 Traditional Chinese Medicine Zheng qi IMMUNITY Biomarkers Functional Assays
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Pharmacological Investigation on the Qi-Invigorating Action of Schisandrin B: Effects on Mitochondrial ATP Generation in Multiple Tissues and Innate/Adaptive Immunity in Mice
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作者 Hoi Yan Leung Suen Chit Sze Kam Ming Ko 《Chinese Medicine》 CAS 2024年第2期15-26,共12页
Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five visceral organs. Our laboratory ha... Schisandrae Fructus, containing schisandrin B (Sch B) as its main active component, is recognized in traditional Chinese medicine (TCM) for its Qi-invigorating properties in the five visceral organs. Our laboratory has shown that the Qi-invigorating action of Chinese tonifying herbs is linked to increased mitochondrial ATP generation and an enhancement in mitochondrial glutathione redox status. To explore whether Sch B can exert Qi-invigorating actions across various tissues, we investigated the effects of Sch B treatment on mitochondrial ATP generation and glutathione redox status in multiple mouse tissues ex vivo. In line with TCM theory, which posits that Zheng Qi generation relies on the Qi function of the visceral organs, we also examined Sch B’s impact on natural killer cell activity and antigen-induced splenocyte proliferation, both serving as indirect measures of Zheng Qi. Our findings revealed that Sch B treatment consistently enhanced mitochondrial ATP generation and improved mitochondrial glutathione redox status in mouse tissues. This boost in mitochondrial function was associated with stimulated innate and adaptive immune responses, marked by increased natural killer cell activity and antigen-induced T/B cell proliferation, potentially through the increased generation of Zheng Qi. 展开更多
关键词 Zheng qi Schisandrin B Mitochondria ATP Generation Glutathione Redox Innate Immunity Adaptive Immunity Natural Killer Cell Activity Splenocyte Proliferation
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Observation on the Nursing Effect of Ginger Moxibustion on Gastrointestinal Symptoms in Patients with Heart Failure Due to Yang Qi Deficiency
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作者 Yijing Wang 《Journal of Clinical and Nursing Research》 2024年第6期135-141,共7页
Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi defi... Objective:To evaluate the nursing measures and effects of ginger moxibustion in the treatment of heart failure(yang qi deficiency type)with gastrointestinal symptoms.Methods:86 patients with heart failure(yang qi deficiency type)accompanied by gastrointestinal symptoms who were admitted to the hospital between January 2023 and January 2024 were selected and divided into 43 cases in each group by random number table grouping;Group I implemented integrated care,while Group II adopted conventional care.The indicators of care were compared between the two groups.Results:After the nursing care,the digestive symptom scores of Group I were lower than those of Group I,and the psychological scores were lower than those of Group II(P<0.05).Conclusion:Ginger moxibustion can improve gastrointestinal symptoms and enhance the psychological health of patients with heart failure(yang qi deficiency type)with gastrointestinal symptoms. 展开更多
关键词 Ginger moxibustion Yang qi deficiency Heart failure Gastrointestinal symptoms
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Traditional Chinese medicine Qi model
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作者 Rui Chen 《TMR Theory and Hypothesis》 2020年第2期311-324,共14页
This paper expounds the effect of"Qi"on human body by constructing the model of Qi,classifies the parts according to the category of Yin and Yang on the coordinate frame of 5 models of Yin and Yang,and compa... This paper expounds the effect of"Qi"on human body by constructing the model of Qi,classifies the parts according to the category of Yin and Yang on the coordinate frame of 5 models of Yin and Yang,and compares each kind of parts according to the normal image state of human body.with the running direction of integer instead of Qi,the number of Qi in each part is calculated by the method of modern number theory,and the development and changes of human physiology and diseases are explained by"Qi".To explore the Trasitional Chinese Medicine treatment method of"the morbid Qi state of the human body adjusts the qi mode,the direction of qi operation and the intensity of Qi by means of medicinal taste and acupuncture,and returns to the normal state of qi balance mode in the direction of operation". 展开更多
关键词 Frame of reference Analogy of image acquisition Integer yin and yang Yin and yang number 5 model Image state qi qi model State of qi qi mode Running direction of qi qi number qi intensity
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Doctor Song Fuyin's Experience in Treating Hashimoto's Thyroiditis Based on Qi,Blood Essence and Spirit Syndrome Differentiation Stage Classification
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作者 李晓红 宋福印 庄扬名 《World Journal of Integrated Traditional and Western Medicine》 2023年第2期53-60,共8页
The paper systematically summarizes the experience of Director Song Fuyin in treating Hashimoto's thyroiditis which is a typical emotional disease that causes obvious changes in organ morphology and endocrine and ... The paper systematically summarizes the experience of Director Song Fuyin in treating Hashimoto's thyroiditis which is a typical emotional disease that causes obvious changes in organ morphology and endocrine and body fluid metabolism.It belongs to the category of psychosomatic diseases,and is the embodiment of a series of pathogenesis processes of qi disease,blood disease,essence disease and deformation in TCM theory.The whole course of the disease is dominated by the dialectical relationship of mutual influence,mutual control,mutual root and mutual use among the deity disease,qi disease,blood disease,essence and spiritual disease.Therefore,the treatment emphasizes the dialectical relationship based on qi,blood,essence and spirit.At the beginning,the treatment focuses on regulating qi and clearing heat and eliminating phlegm;at the middle stage,the treatment focuses on replenishing essence and promoting yang and eliminating wind and calming the deity;at the late stage,the treatment focuses on replenishing qi and eliminating phlegm and promoting collages.Flexible use of calming the spirits,regulating qi,dispersing essence,eliminating phlegm,promoting blood and other methods of stage classification treatment,can be targeted,improve the cure rate of the disease.This article aims to clarify the experience of Director Song Fuyin in treating Hashimoto's thyroiditis based on syndrome differentiation of qi,blood essence and spirit. 展开更多
关键词 Hashimoto's thyroiditis Song Fuyin Differentiation of qi blood essence and spirit.Experience of famous doctors Regulating qi and clearing heat Nourishing essence and enhancing yang Quenching the wind and calming the spirit Eliminating phlegm and clearing collaterals
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Unstable periodic orbits analysis in the Qi system
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作者 贾莲 董成伟 +1 位作者 李瀚涛 眭晓红 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第4期237-248,共12页
We use the variational method to extract the short periodic orbits of the Qi system within a certain topological length.The chaotic dynamical behaviors of the Qi system with five equilibria are analyzed by the means o... We use the variational method to extract the short periodic orbits of the Qi system within a certain topological length.The chaotic dynamical behaviors of the Qi system with five equilibria are analyzed by the means of phase portraits,Lyapunov exponents,and Poincarémaps.Based on several periodic orbits with different sizes and shapes,they are encoded systematically with two letters or four letters for two different sets of parameters.The periodic orbits outside the attractor with complex topology are discovered by accident.In addition,the bifurcations of cycles and the bifurcations of equilibria in the Qi system are explored by different methods respectively.In this process,the rule of orbital period changing with parameters is also investigated.The calculation and classification method of periodic orbits in this study can be widely used in other similar low-dimensional dissipative systems. 展开更多
关键词 CHAOS periodic orbits BIFURCATION qi system
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The First Documented Experience of Qi and an Account of Healing Failure:4th-Century BCE
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作者 Constance A.Cook 《Chinese Medicine and Culture》 2023年第2期139-146,共8页
This essay will review the earliest case that documents a patient’s experience of qi,one found on a bamboo text buried with the patient who died in the 318 BCE.Details of the healing encounter and of concepts of illn... This essay will review the earliest case that documents a patient’s experience of qi,one found on a bamboo text buried with the patient who died in the 318 BCE.Details of the healing encounter and of concepts of illness show how non-transmitted documents hidden from later editors in tombs preserve an older layer of medical understanding than that in transmitted canons,such as the Huang Di Nei Jing(Inner Canon of the Yellow Emperor).The 4th-century BCE case record described below is the longest early medical record concerning the treatment of a specific individual.It is also an account of failure formally recorded for the sake of the survivors and buried with the dead to be transmitted to the world of the spirits.The essay begins with a reevaluation of ancient concept of qi and then moves on to the individual case record. 展开更多
关键词 Ancient DIVINATION Heart Magic MANUSCRIPT qi Wu Xing YIN-YANG
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Nashville Qi?Chinese Medicine in an American Heartland
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作者 Ruth Rogaski 《Chinese Medicine and Culture》 2023年第3期224-232,共9页
This article shares preliminary results from current research on Chinese medicine in Nashville,Tennessee,a city in the American South known both as“Music City,USA”and“The Buckle of the Bible Belt.”The author has i... This article shares preliminary results from current research on Chinese medicine in Nashville,Tennessee,a city in the American South known both as“Music City,USA”and“The Buckle of the Bible Belt.”The author has interviewed dozens of patients and practitioners in Nashville to understand how Chinese medicine came to the city,what styles of practice are present,and whether or not new understandings of Chinese medicine’s fundamental concept of qi might emerge from the unique cultural setting of the American South.While Chinese medicine is flourishing in the city,because of complexities at the intersection of religion,science,and the experience of healing,the clinical encounter between patients and practitioners is not typically characterized by a mutual embrace of a language of qi. 展开更多
关键词 Chinese medicine Nashville qi United States
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Effect of Sijunzi Decoction on the Myonuclear Domain of Rat Soleus in Spleen Qi Deficiency
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作者 Linlin Zhang Dan Ma +3 位作者 Songnan Wang Xudong Liu Lingzhi Wang Dehong Shan 《Chinese Medicine》 2023年第4期276-285,共10页
Objective: To study the mechanism of Sijunzi decoction treating limb weakness in spleen Qi deficiency (SQD) based on the myonuclear domain (MND) theory. Methods: 40 male Sprague-Dawley rats were randomly divided into ... Objective: To study the mechanism of Sijunzi decoction treating limb weakness in spleen Qi deficiency (SQD) based on the myonuclear domain (MND) theory. Methods: 40 male Sprague-Dawley rats were randomly divided into the normal group, SQD model group (model group), SQD+ still water group (SW group) and SQD+ Sijunzi decoction group (CM group), 10 rats each group;Grip-Strength Meter was used to measure limb grip strength;transmission electron microscope was employed to observe the ultrastructural changes of the myofibers, Image Pro 6.0 was used to measure the myonuclear numbers, cross-section area (CSA) and then their ratios (the MND sizes) were calculated, immunofluorescence assay was chosen to test the expressions of paired box gene 7 (Pax7) and myogenic differentiation antigen (MyoD). Results: Compared with those in the normal group, limb grip strength was decreased, sarcomeres were abnormal, and all the myonuclear numbers, CSA and MND sizes were reduced, but the Pax7+ cell numbers were increased, significantly, in the model and SW groups;Compared with those in the model and SW groups, limb grip strength was increased, sarcomeres were basically normal, the myonuclear number and CSA were both greater, and the Pax7+ and MyoD+ cell numbers were both increased, significantly, in the CM group. Conclusion: Sijunzi decoction might increase the myonuclear number by activating the MSCs to treat limb weakness in SQD. 展开更多
关键词 Sijunzi Decoction Spleen qi Deficiency Limb Weakness Myonuclear Domain Muscle Stem Cell
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Clinical effects of a traditional Chinese medicine nursing programme to intervene in gastric pain of the spleen and stomach with Qi deficiency
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作者 Yin-Hong Yu Yu-Shuang Yu Xiao-He Cheng 《World Journal of Clinical Cases》 SCIE 2023年第21期5056-5062,共7页
BACKGROUND Gastroparesis is a common digestive disorder characterized by delayed gastric emptying,which can lead to symptoms such as nausea,vomiting,abdominal pain,and poor appetite.Traditional Chinese medicine(TCM)ha... BACKGROUND Gastroparesis is a common digestive disorder characterized by delayed gastric emptying,which can lead to symptoms such as nausea,vomiting,abdominal pain,and poor appetite.Traditional Chinese medicine(TCM)has been used for centuries to treat gastrointestinal disorders,including gastroparesis.TCM theory suggests that spleen and stomach qi deficiency syndrome is one of the main pathogenic factors in gastroparesis.Nursing care plays an important role in the treatment of gastroparesis,and TCM nursing interventions have shown promising results in improving patient outcomes.However,there is limited research on the clinical effectiveness of TCM nursing interventions for gastroparesis with spleen stomach deficiency syndrome.This study aimed to evaluate the clinical effect of TCM nursing intervention in the treatment of gastroparesis with spleen stomach deficiency syndrome and to compare it with routine nursing interventions.AIM To analyze the clinical effect of traditional Chinese medicine nursing intervention in the treatment of gastric paraplegia with spleen stomach deficiency syndrome.METHODS From January 2020 to July 2021,80 patients with gastroparesis of spleen stomach qi deficiency type diagnosed in our hospital were selected for the study.The 80 patients were randomly divided into a control group and an experimental group,with 40 cases in each group.During the treatment period,the control group received routine nursing interventions,while the experimental group received traditional Chinese medicine nursing procedures.Compare the nursing effects of the two groups and observe the changes in traditional Chinese medicine symptom scores,pain levels,and sleep quality before and after treatment.RESULTS After treatment,comparing the treatment effects of the two groups,the total effective rate of the experimental group was significantly higher than that of the control group,with statistical significance(P<0.05).There was no statistically significant difference in the TCM symptom score,visual analogue scale(VAS)score,and Pittsburgh sleep quality index(PSQI)score between the two groups before treatment(P>0.05).However,after treatment,the TCM syndrome scores,VAS scores,and PSQI scores of the experimental group were significantly lower than those of the control group,with a statistically significant difference(P<0.05).CONCLUSION In the clinical nursing intervention of patients with mild gastroparesis due to spleen and stomach qi deficiency,the traditional Chinese medicine nursing plan has good clinical application value and nursing effect,and has a good effect on improving patients’pain and sleep quality. 展开更多
关键词 Chinese medicine nursing programme Spleen and stomach qi deficiency type Gastric and epigastric pain Nursing effect PAIN Sleep quality
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基于5QI精确调度空口资源测试研究
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作者 吕昌金 马传项 《江苏通信》 2023年第3期29-33,共5页
移动通信网络传输等有线资源较为充足,容易受限的是无线空口资源。当5G用户数较多,此时空口资源不足,需要根据用户等级精准调度空口资源,做到空口资源正比公平分配。本案例研究通过差异化设置5QI做到精准分配无线资源,合理化分配空口资... 移动通信网络传输等有线资源较为充足,容易受限的是无线空口资源。当5G用户数较多,此时空口资源不足,需要根据用户等级精准调度空口资源,做到空口资源正比公平分配。本案例研究通过差异化设置5QI做到精准分配无线资源,合理化分配空口资源,提升用户满意度。 展开更多
关键词 QCI 5qi QoSFlow 加权因子
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脱除煤焦油中原生QI杂质的方法和条件 被引量:5
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作者 薛改凤 许斌 刘瑞周 《煤化工》 CAS 1997年第4期46-49,共4页
研究了煤焦油净化处理过程中絮凝剂种类、焦油水分含量、净化处理温度和静置时间对净化效果的影响,净化澄清液QI含量为0.2%~0.5%。
关键词 煤焦油 净化 qi杂质 原生qi杂质
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Experience in the Treatment of Tumors by Replenishing Qi and Nourishing Blood,Detoxicating and Resolving Masses
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作者 刘楠楠 陈士洲 魏丽华 《World Journal of Integrated Traditional and Western Medicine》 2021年第3期37-41,共5页
The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the cl... The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the clinical experiences in tumor treatment of Dr.Chen Shizhou,a well-known traditional Chinese medicine expert in Weifang City,Shandong Province.He put forward the treatment method of"replenishing Qi and nourishing blood,detoxicating and resolving masses",paying attention to protecting stomach qi and advocating survival with tumor,with remarkable clinical effects. 展开更多
关键词 Malignant tumors The deficiency of vital qi and the excess of pathogenic qi Strengthening vital qi to eliminate pathogenic factor Replenishing qi and nourishing blood Detoxicating and resolving masses Protecting stomach qi
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Qi系统的Hopf分叉分析与幅值控制 被引量:12
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作者 刘素华 赵成刚 +1 位作者 唐驾时 杨先林 《动力学与控制学报》 2008年第2期141-145,共5页
通过非线性状态反馈,不改变Hopf分叉点,实现对四维Qi系统极限环的幅值控制.推导出Qi系统在第一类非零平衡点上产生Hopf分叉的条件,绘制第一类平衡点的分叉图.采用washout filter非线性控制律,利用中心流形定理对受控系统降维,得到极限... 通过非线性状态反馈,不改变Hopf分叉点,实现对四维Qi系统极限环的幅值控制.推导出Qi系统在第一类非零平衡点上产生Hopf分叉的条件,绘制第一类平衡点的分叉图.采用washout filter非线性控制律,利用中心流形定理对受控系统降维,得到极限环的幅值与控制增益之间的近似解析式.通过数值模拟以及幅值解析解与数值解的比较,验证幅值预测的正确性与控制的有效性. 展开更多
关键词 qi系统 HOPF分叉 极限环 幅值控制
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过滤精度对煤焦油QI的组成和结构的影响 被引量:3
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作者 王磊 李冬 +4 位作者 毕瑶 黄江流 朱永红 张琳娜 袁扬 《煤炭学报》 EI CAS CSCD 北大核心 2017年第4期1043-1049,共7页
采用精度为2~5μm和20~40μm的滤芯分别对煤焦油进行热过滤,从得到的滤渣中提取出喹啉不溶物(QI)。然后利用元素分析(EA)、激光粒度仪(LPSA)、扫描电子显微镜/X射线能量色散光谱(SEM/EDS)、傅里叶红外光谱(FT-IR)、X射线衍射仪(XRD)、X... 采用精度为2~5μm和20~40μm的滤芯分别对煤焦油进行热过滤,从得到的滤渣中提取出喹啉不溶物(QI)。然后利用元素分析(EA)、激光粒度仪(LPSA)、扫描电子显微镜/X射线能量色散光谱(SEM/EDS)、傅里叶红外光谱(FT-IR)、X射线衍射仪(XRD)、X射线光电子能谱(XPS)等对所得煤焦油QI组分进行对比分析。结果表明:煤焦油QI组分芳构化程度高,有机物多为稠环类物质并带有很多侧链或杂质原子,同时存在少量石英石、方解石以及煤灰等无机物;当煤焦油热过滤时采用的滤芯精度较低时,最终提取出的QI组分缩聚度相对较高,并且稠环结构中所含侧链和杂原子也相对较少。经精度较低的滤芯热过滤后提取的QI组分中金属杂原子含量相对较高,这些金属杂原子主要存在于大颗粒无机物中,部分存在于小颗粒有机物中。当滤芯精度较高时所得QI组分中主要含酚类、醚类和羧酸类有机物,酮类含量相对较少;反之,QI中则主要含酚类、醚类和酮类有机物。因此,煤焦油热过滤所选的滤芯精度不宜过高,尤其不宜选精度在5μm以下的滤芯。 展开更多
关键词 滤芯 喹啉不溶物(qi) 表征 对比分析
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建立结点上弧-弧拓扑关系的Qi算法 被引量:25
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作者 齐华 刘文熙 《测绘学报》 EI CSCD 北大核心 1996年第3期233-235,共3页
建立结点上弧-弧拓扑关系的Qi算法齐华,刘文熙(成都西南交通大学,610031)1引言在地理信息系统中,“自动生成多边形拓扑关系”是一个使用频率很高的过程。如何优化算法来提高这个过程的时间效率是一个十分有意义的问题。... 建立结点上弧-弧拓扑关系的Qi算法齐华,刘文熙(成都西南交通大学,610031)1引言在地理信息系统中,“自动生成多边形拓扑关系”是一个使用频率很高的过程。如何优化算法来提高这个过程的时间效率是一个十分有意义的问题。对于这个过程的研究引起了学者们的关... 展开更多
关键词 GIS 结点 弧-弧拓扑 qi算法
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Effect of Huangqi Xiaoke Recipe combined with alprostadil on qi and yin deficiency type diabetic nephropathy and its effect on vascular endothelium and oxidative stress
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作者 Rui-Bin Chen Ji-Bin Zeng Li Gong 《Journal of Hainan Medical University》 2019年第7期10-14,共5页
Objective: To observe the clinical efficacy of Huangqi Xiaoke Decoction combined with alprostadil on qi and yin deficiency type diabetic nephropathy (DN) and its effect on vascular endothelium and oxidative stress. Me... Objective: To observe the clinical efficacy of Huangqi Xiaoke Decoction combined with alprostadil on qi and yin deficiency type diabetic nephropathy (DN) and its effect on vascular endothelium and oxidative stress. Methods: A total of 72 patients with qi and yin deficiency type DN who were admitted to the diabetes specialist ward and outpatient department of Baoan District Hospital of Shenzhen from January 2017 to July 2018 were enrolled. The patients were divided into the control group and the observation group according to the random number method. 36 cases in each group. Both groups were treated with conventional treatments such as hypoglycemic, hypotensive, lipid-lowering and anti-platelet aggregation. The control group was treated with alprostadil on the basis of conventional treatment. The observation group was given orally on the basis of the control group. Both groups were treated once a day for a total of 4 weeks. Compare the clinical syndrome scores and clinical efficacy of the two groups before and after treatment;fasting blood glucose (FPG), glycosylated hemoglobin (HbA1C), blood lipids (TC, TG, LDL, HDL), serum creatinine (SCr), blood urea nitrogen (BUN Endothelin-1 (ET-1), nitric oxide (NO), von Willebrand factor (vWF);glutathione peroxidase (GSH-Px), superoxide disproportionation The level of enzyme (SOD), malondialdehyde (MDA). Results:The total effective rate of TCM syndromes in observation group was 94.44%, which was significantly different from 72.22% in the control group. The scores of TCM syndromes in the observation group were significantly lower than those in the control group;Compared with the control group, the HDL-C of the observation group did not change much, there was no statistical difference;FBG, HbA1C, SCr, BUN, TC, TG, LDL-C, ET-1, vWF, MDA Significantly decreased, NO, GSH-Px, SOD increased significantly, with significant difference. Conclusion: Huangqi Xiaoke Decoction combined with alprostadil in the treatment of qi and yin deficiency type DN has significant curative effect, which can not only lower blood sugar, regulate blood lipids, improve renal function and clinical symptoms, but also inhibit oxidative stress and protect endothelial function. 展开更多
关键词 Huangqi Xiaoke Decoction qianlie Dilt qi and Yin deficiency TYPE diabetic NEPHROPATHY Vascular ENDOTHELIUM Oxidative stress
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基于Qi算法的Delaunay三角网逐点插入法 被引量:3
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作者 杨琦明 周晓光 +2 位作者 张剑 王美玲 周辉 《遥感信息》 CSCD 2011年第1期92-96,共5页
Delaunay三角网在很多领域都有着广泛的应用,快速高效地生成Delaunay三角网十分重要。逐点插入法是构建Delaunay三角网中使用最广泛的方法之一。本文深入研究了使用逐点插入法构建不带约束条件Delaunay三角网的过程。在使用该方法生成De... Delaunay三角网在很多领域都有着广泛的应用,快速高效地生成Delaunay三角网十分重要。逐点插入法是构建Delaunay三角网中使用最广泛的方法之一。本文深入研究了使用逐点插入法构建不带约束条件Delaunay三角网的过程。在使用该方法生成Delaunay三角网中建立结点拓扑关系这一影响构网效率的关键步骤中引入了Qi算法,简化了该方法生成Delaunay三角网的复杂度。然后在向Delaunay三角网内插入约束边的过程中,再次引入Qi算法,从而提高了构网的效率。为了验证上述模型,我们在Microsoft Visual Studio 2005开发环境下,以C#为开发工具,采用底层开发模式实现了改进的逐点插入法,实验证明引入Qi算法能够提高逐点插入法Delaunay三角网构建及插入约束边的效率。 展开更多
关键词 DELAUNAY三角网 拓扑关系 qi算法 效率
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煤沥青中原生QI性质分析 被引量:8
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作者 任绍梅 熊杰明 《炭素技术》 CAS CSCD 2008年第1期13-15,共3页
利用元素分析、红外光谱、激光粒度仪、原子发射光谱仪等分析手段对攀钢中温煤沥青的原生QI进行了结构组成分析。结果表明,原生QI粒径90%以上小于2μm,为无定型的微晶乱堆结构,其灰分质量分数达到5.8%。元素分析和红外光谱分析表明,QI... 利用元素分析、红外光谱、激光粒度仪、原子发射光谱仪等分析手段对攀钢中温煤沥青的原生QI进行了结构组成分析。结果表明,原生QI粒径90%以上小于2μm,为无定型的微晶乱堆结构,其灰分质量分数达到5.8%。元素分析和红外光谱分析表明,QI有机成分主要为高度缩合的炭黑状物质,金属分析表明无机成分主要由耐火材料粉屑和铁件的氧化物构成。这为原生QI的脱除提供了科学依据。 展开更多
关键词 原生qi 结构 分析
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