加味补阳还五汤治疗缺血性中风(气虚血瘀证)的疗效观察及安全性评估

目的 观察加味补阳还五汤治疗缺血性中风(气虚血瘀证)的临床疗效并探讨其作用机制。方法 100例患者按随机数字表法分为试验组与对照组各50例。对照组给予常规治疗。试验组在对照组常规治疗基础上加服加味补阳还五汤。两组疗程均为2周。于治疗前、治疗后14 d分别根据神经功能缺损量表(NIHSS)评分、日常生活活动能力量表(ADL)评分、改良金兰量表(MRS)评分、中医证候疗效评价两组的临床疗效。在治疗前、治疗后14 d检查患者肝功、肾功、大便隐血,观察患者有无恶心呕吐、腹泻的不良反应,从而评估其安全性。结果 试验组总有效率为96.00%,高于对照组的78.00%(P <0.05)。两组治疗后中医证候评分与治疗前比较均降低,且观察组中医证候各项评分均低于对照组(均P <0.05)。两组治疗后NIHSS、MRS评分与治疗前比较均降低,ADL量表评分则均升高,且观察组各项指标评分情况均优于对照组(均P <0.05)。两组患者治疗期间均未出现明显不良反应,患者肝功、肾功、大便隐血均未见明显变化,安全性良好。结论 加味补阳还五汤联合西医常规治疗缺血性中风(气虚血瘀证),可提高临床总有效率,促进患者自理能力和神经功能恢复,降低致残率,改善预后,提高患者生活质量。

加服益气活血方对急性冠脉综合征PCI术后气虚血瘀证患者左心室功能及生活质量的影响

[目的]探究加服益气活血方对急性冠脉综合征(ACS)经皮冠状动脉介入(PCI)术后气虚血瘀证患者左心室功能及生活质量的影响。[方法]收集104例急性冠脉综合征PCI术后气虚血瘀证患者病历,按治疗方案不同分成中西医组52例和西医组52例,西医组予常规西医治疗,中西医组在常规西医治疗基础上加服益气活血方,两组均治疗2个月,比较两组治疗前后左心室功能指标[左心室收缩末内径(LVESD)、左心室短轴缩短率(FS)、左心室射血分数(LVEF)]、血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)及西雅图心绞痛量表(SAQ)评分。[结果]治疗2个月后,中西医组LVESD、IL-6、TNF-α水平较西医组低,FS、LVEF较西医组高(P<0.01);治疗1个月、2个月后,中西医组SAQ评分均较西医组高(P<0.05)。[结论]加服益气活血方可进一步改善急性冠脉综合征PCI术后气虚血瘀证患者左心室功能,减轻炎性反应,提高生活质量。

十一味参芪片对气血两虚型消化道恶性肿瘤化疗效果的影响

【目的】探讨十一味参芪片对气血两虚型消化道恶性肿瘤化疗后临床疗效的影响。【方法】本院收治的气血两虚型消化道恶性肿瘤患者90例，随机分为观察组和对照组，每组45例。两组患者均进行化疗治疗，对照组在此基础上给予鲨肝醇治疗，观察组给予鲨肝醇＋十一味参芪片治疗。比较两组患者治疗后症状改善、生活质量及白细胞下降情况。【结果】观察组总有效率为73．33％（33／45），明显高于对照组42．22％（19／45），且差异有显著性（P〈0．05）；两组治疗后白细胞均有不同程度的减少，但对照组减少比例明显高于观察组，且差异有显著性（P〈O．05）；观察组患者治疗后各项生活质量评分明显高于对照组（P〈0．05）。【结论】十一味参芪片能减缓气血两虚型消化道恶性肿瘤患者化疗后的毒副作用，提高患者治疗后的生活质量，具有一定的临床疗效，值得推广应用。

Treatment of 30 Cases of Vertigo due to Qi-blood Deficiency by Pricking Jingbailao (EX-HN 15) with Fire Needle Therapy

Objective: To observe the clinical effect of fire needle therapy on vertigo due to qi-blood deficiency by pricking Jingbailao (EX-HN 15). Methods: Thirty cases with vertigo due to qi-blood deficiency in conformity with the inclusion criteria were treated with fire needle therapy by pricking Jingbailao (EX-HN15), once every day, seven sessions as one course. The clinical effects were assessed after one course of treatment. Results: After one-course treatment, the results showed cure in 3 cases, remarkable effect in 14 cases, effect in 11 cases and failure in 2 cases out of 30 cases. Conclusion: Fire needle therapy by pricking Jingbailao (EX-HN15) can obviously relieve the clinical symptoms in patients with vertigo due to qi-blood deficiency.

Detwmination of Blood Flow in the Lower Leg of Patients withDiabetes Mellitus and the Effects of Treatment with thePrinciple of Vitalizing Blood and Solubilizing Thrombus

Blood flow in the lower leg was determined in 50 cases of non-insulin dependent diabetesmellitus using an XLJ-2 bipolar rheoencephalometry impedance rheogram. In patients with leg pain (85legsi and diabetic foat (15 legs3, the blood flow of the lower leg was decreased as compared withhealthy legs (P<0. 01￣0. 001) . The group with diabetic foot showed a bigger decrease compared withthe leg pain group (PMO. 051 . Atter treatment with the principle of vitalizing blood and solubilizing throm-bus, 22 cases with leg pain (32 legs) showed a significant increase of blood flow in the lower leg (P<0. 001). The group with diabetic foot failed to show any significant increase, indicating the importance ofearly treatment. This method of determining blood flow in the lower leg will help early discovery of abnor-mal changes of blood supply in the lower leg. Treatment with the principle of vitalizing blood and solubiliz-ing thrombus can help improve the conditions of the patients.