Ancient DNA was extracted from 13 skeletal remains from the burial groups of Khitan nobles, which were excavated in northeast China. The hypervariable segment Ⅰ sequences （ HVS Ⅰ ） of the mitochondrial DNA control...Ancient DNA was extracted from 13 skeletal remains from the burial groups of Khitan nobles, which were excavated in northeast China. The hypervariable segment Ⅰ sequences （ HVS Ⅰ ） of the mitochondrial DNA control region, in the 13 individuals, were used as genetic markers to determine the genetic relationships between the individuals and the genetic affinity to other interrelated populations by using the known database of mtDNA. Based on the phylogenetic analysis of these ancient DNA sequences, the genetic structures of two Khitan noble kindreds were obtained, including the Yel Yuzhi＇s kindred and the Xiao He＇s kindred. Furthermore, the relationships between the Khitan nobles and some modern interrelated populations were analyzed. On the basis of the result of the analysis, the gene flows of the ancient Khitans and their demographic expansion in history was deduced.展开更多
Objective: To evaluate the therapeutic effects and mechanisms of Qidan granule in blemycinA5-induced pulmonary interstitial fibrosis (PIF)in rats. Methods: PIF models were established by blemycinA5-induced in rats. Th...Objective: To evaluate the therapeutic effects and mechanisms of Qidan granule in blemycinA5-induced pulmonary interstitial fibrosis (PIF)in rats. Methods: PIF models were established by blemycinA5-induced in rats. They were treated by Qidan granule and Hydrocortisone respectively. The pathological changes and collagen protein disposition were observed, and the expression of TGF-β, TNF-α proteins were measured by immunohistochemical technique. Results: The pulmonary alveolitis and fibrosis were alleviated remarkably in Qidan granule group compared with those in the model control group and hydrocortisone group (P<0.01). The expression of TGF-β and TNF-α protein were higher in Qidan granule group than those in normal group ,and were significantly less than those in the model control group and in hydrocortisone group (P<0.01). Conclusion: Qidan granule would ameliorate the pulmonary alveolitis and fibrosis. TGF-β and TNF-α might play an important role in the development of alveolitis and fibrosis in rats.展开更多
Cauterization(Perian:Dāgh/Arabic:Al-Kayy or Al-Wasm)is one of the oldest methods of treatment in most ancient cultures and medical schools;the history of these methods,with archaeological studies,is estimated to be m...Cauterization(Perian:Dāgh/Arabic:Al-Kayy or Al-Wasm)is one of the oldest methods of treatment in most ancient cultures and medical schools;the history of these methods,with archaeological studies,is estimated to be more than a few thousand years,and this issue can determine the reason for the spread of cauterizing methods in the traditional medicine of ancient civilizations,including Iran and China.The present research,as a descriptive/historical research,tries to examine the text of the manuscript of Tanksuq-nāmeh;and identify the theoretical foundations and practical methods of cauterization in Chinese and Khitans medicine,based on one of the key texts of the Ilkhanid period.(Text translated from Chinese to Persian in the 14th century AD)The results of the present study show that cauterization has a long history among the Chinese and Khitans peoples and has been performed in different ways and for different diseases.展开更多
文摘Ancient DNA was extracted from 13 skeletal remains from the burial groups of Khitan nobles, which were excavated in northeast China. The hypervariable segment Ⅰ sequences （ HVS Ⅰ ） of the mitochondrial DNA control region, in the 13 individuals, were used as genetic markers to determine the genetic relationships between the individuals and the genetic affinity to other interrelated populations by using the known database of mtDNA. Based on the phylogenetic analysis of these ancient DNA sequences, the genetic structures of two Khitan noble kindreds were obtained, including the Yel Yuzhi＇s kindred and the Xiao He＇s kindred. Furthermore, the relationships between the Khitan nobles and some modern interrelated populations were analyzed. On the basis of the result of the analysis, the gene flows of the ancient Khitans and their demographic expansion in history was deduced.
基金Supported by the National Natural Science Foundation of China(No.30271625).
文摘Objective: To evaluate the therapeutic effects and mechanisms of Qidan granule in blemycinA5-induced pulmonary interstitial fibrosis (PIF)in rats. Methods: PIF models were established by blemycinA5-induced in rats. They were treated by Qidan granule and Hydrocortisone respectively. The pathological changes and collagen protein disposition were observed, and the expression of TGF-β, TNF-α proteins were measured by immunohistochemical technique. Results: The pulmonary alveolitis and fibrosis were alleviated remarkably in Qidan granule group compared with those in the model control group and hydrocortisone group (P<0.01). The expression of TGF-β and TNF-α protein were higher in Qidan granule group than those in normal group ,and were significantly less than those in the model control group and in hydrocortisone group (P<0.01). Conclusion: Qidan granule would ameliorate the pulmonary alveolitis and fibrosis. TGF-β and TNF-α might play an important role in the development of alveolitis and fibrosis in rats.
基金specific grant from any funding agency in the public,commercial,or not-for-profit sectors.
文摘Cauterization(Perian:Dāgh/Arabic:Al-Kayy or Al-Wasm)is one of the oldest methods of treatment in most ancient cultures and medical schools;the history of these methods,with archaeological studies,is estimated to be more than a few thousand years,and this issue can determine the reason for the spread of cauterizing methods in the traditional medicine of ancient civilizations,including Iran and China.The present research,as a descriptive/historical research,tries to examine the text of the manuscript of Tanksuq-nāmeh;and identify the theoretical foundations and practical methods of cauterization in Chinese and Khitans medicine,based on one of the key texts of the Ilkhanid period.(Text translated from Chinese to Persian in the 14th century AD)The results of the present study show that cauterization has a long history among the Chinese and Khitans peoples and has been performed in different ways and for different diseases.
