AIM:To find the way to improve the eradication rate of first-line therapy in Japanese patients.METHODS:We prospectively compared the effectiveness of 7-d quadruple therapy to standard 7 d triple therapy in Japanese pa...AIM:To find the way to improve the eradication rate of first-line therapy in Japanese patients.METHODS:We prospectively compared the effectiveness of 7-d quadruple therapy to standard 7 d triple therapy in Japanese patients infected with Helicobacter pylori(H.pylori).One hundred and nineteen patients were randomly assigned to receive 7-d non-bismuth quadruple therapy with lansoprazole,amoxicillin,clarithromycin and metronidazole(LACM7) or 7-d triple therapy with lansoprazole,amoxicillin and clarithromycin(LAC7).After three months,H.pylori status was analyzed by 13C-urea breath test.Incidence rates of adverse events were evaluated by use of questionnaires.RESULTS:By intention-to-treat(ITT) analysis,the eradication rate in the LACM7 group was 94.9%,which was significantly higher than the LAC7 group(68.3%,P < 0.001).Per protocol analysis also showed a significantly higher eradication rate in the LACM7 group(98.3%) than the LAC7 group(73.2%,P < 0.001).Nevertheless,the incidence of serious adverse events did not differ between the two groups(RR:1.10,95% CI:0.70-1.73,P = 0.67).CONCLUSION:Seven day non-bismuth quadruple therapy(LACM7) was superior to standard 7-d triple therapy(LAC7) for first-line eradication.展开更多
Self-aligned multiple patterning (SAMP) can enable the semiconductor scaling before EUV lithography becomes mature for industry use.Theoretically any small size of pitch can be achieved by repeating SADP on same wafer...Self-aligned multiple patterning (SAMP) can enable the semiconductor scaling before EUV lithography becomes mature for industry use.Theoretically any small size of pitch can be achieved by repeating SADP on same wafer but with challenges of pitch walking and line cut since line cut has to be done by lithography instead of self-aligned method.Line cut can become an issue at sub-30nm pitch due to edge placement error (EPE).In this paper we will discuss some recent novel ideas on line cut after self-aligned multiple patterning.展开更多
输电线路带电水冲洗是电力系统防污闪的主要措施之一。500 k V输电线路4联污秽绝缘子串具有间距小、污秽重、难以清洗等特点,为实现其带电水冲洗,在武汉大学户外带电水冲洗试验场进行了冲洗试验,比较了4个污秽度等级下1冲4回和1冲6回这...输电线路带电水冲洗是电力系统防污闪的主要措施之一。500 k V输电线路4联污秽绝缘子串具有间距小、污秽重、难以清洗等特点,为实现其带电水冲洗,在武汉大学户外带电水冲洗试验场进行了冲洗试验,比较了4个污秽度等级下1冲4回和1冲6回这2种冲洗方法。结果表明:冲洗过程中在较长冲洗时间段泄漏电流幅值都<10 m A;冲洗到绝缘子串上部3/4及5/6位置附近处时出现了泄漏电流突增现象;冲洗泄漏电流基波幅值最大值、结束时刻泄漏电流基波幅值随污秽度等级增大而增大。4种污秽度等级下,1冲4回和1冲6回冲洗过程中泄漏电流基波幅值最大值分别小于61 m A和31 m A,这2种方法用于500 k V输电线路4联污秽绝缘子串的带电水冲洗都是安全的。展开更多
文摘AIM:To find the way to improve the eradication rate of first-line therapy in Japanese patients.METHODS:We prospectively compared the effectiveness of 7-d quadruple therapy to standard 7 d triple therapy in Japanese patients infected with Helicobacter pylori(H.pylori).One hundred and nineteen patients were randomly assigned to receive 7-d non-bismuth quadruple therapy with lansoprazole,amoxicillin,clarithromycin and metronidazole(LACM7) or 7-d triple therapy with lansoprazole,amoxicillin and clarithromycin(LAC7).After three months,H.pylori status was analyzed by 13C-urea breath test.Incidence rates of adverse events were evaluated by use of questionnaires.RESULTS:By intention-to-treat(ITT) analysis,the eradication rate in the LACM7 group was 94.9%,which was significantly higher than the LAC7 group(68.3%,P < 0.001).Per protocol analysis also showed a significantly higher eradication rate in the LACM7 group(98.3%) than the LAC7 group(73.2%,P < 0.001).Nevertheless,the incidence of serious adverse events did not differ between the two groups(RR:1.10,95% CI:0.70-1.73,P = 0.67).CONCLUSION:Seven day non-bismuth quadruple therapy(LACM7) was superior to standard 7-d triple therapy(LAC7) for first-line eradication.
文摘Self-aligned multiple patterning (SAMP) can enable the semiconductor scaling before EUV lithography becomes mature for industry use.Theoretically any small size of pitch can be achieved by repeating SADP on same wafer but with challenges of pitch walking and line cut since line cut has to be done by lithography instead of self-aligned method.Line cut can become an issue at sub-30nm pitch due to edge placement error (EPE).In this paper we will discuss some recent novel ideas on line cut after self-aligned multiple patterning.
文摘输电线路带电水冲洗是电力系统防污闪的主要措施之一。500 k V输电线路4联污秽绝缘子串具有间距小、污秽重、难以清洗等特点,为实现其带电水冲洗,在武汉大学户外带电水冲洗试验场进行了冲洗试验,比较了4个污秽度等级下1冲4回和1冲6回这2种冲洗方法。结果表明:冲洗过程中在较长冲洗时间段泄漏电流幅值都<10 m A;冲洗到绝缘子串上部3/4及5/6位置附近处时出现了泄漏电流突增现象;冲洗泄漏电流基波幅值最大值、结束时刻泄漏电流基波幅值随污秽度等级增大而增大。4种污秽度等级下,1冲4回和1冲6回冲洗过程中泄漏电流基波幅值最大值分别小于61 m A和31 m A,这2种方法用于500 k V输电线路4联污秽绝缘子串的带电水冲洗都是安全的。
