This paper discusses the optimization strategy of education and teaching quality assurance systems in applied colleges and universities under the background of digital intelligence.It first summarizes the relevant the...This paper discusses the optimization strategy of education and teaching quality assurance systems in applied colleges and universities under the background of digital intelligence.It first summarizes the relevant theories of digital intelligence transformation and analyzes the impact of digital intelligence transformation on higher education.Secondly,this paper puts forward the principles of constructing the quality assurance system of applied colleges,including strengthening the quality assurance consciousness,improving teachers’digital literacy,and implementing digital intelligence governance.From the practical perspective,this paper expounds on strategies such as optimizing educational teaching resource allocation,constructing a diversified evaluation system of teaching quality,strengthening the construction and training of teaching staff,and innovating teaching management methods.Specific optimization measures are put forward,such as improving policies,regulations,and system guarantees,strengthening cooperation between schools and enterprises,integrating industry,school,and research,building an educational information platform,and improving the monitoring and feedback mechanism of educational quality.展开更多
Background:Rosa chinensis Jacq.and Rosa rugosa Thunb.are not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional medicines.The two plants h...Background:Rosa chinensis Jacq.and Rosa rugosa Thunb.are not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional medicines.The two plants have some differences in efficacy,but the flower buds are easily confused for similar traits.In addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal roses.Therefore,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography fingerprints.Then,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large differences.Differential compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and Meigui.Results:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the samples.Through principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four groups.Partial least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavonoid glycosides,as well as phenolic acids.Eight differential components were screened out by orthogonal partial least-squares discriminant analysis and S-plot analysis.Quantitative analyses of the eight compounds,including gallic acid,ellagic acid,hyperoside,isoquercitrin,etc.,showed that Yueji was generally richer in phenolic acids and flavonoids than Meigui,and the quality of Yueji from Shandong and Hebei was better.It is worth noting that Xinjiang rose is rich in various components,which is worth focusing on more in-depth research.Conclusion:In this study,the fingerprints of Meigui and Yueji were established.The chemical components information of roses was further improved based on non-targeted metabolomics and mass spectrometry technology.At the same time,eight differential components of Meigui and Yueji were screened out and quantitatively analyzed.The research results provided a scientific basis for the quality control and rational development and utilization of Rosae Chinensis Flos and Rosae Rugosae Flos,and also laid a foundation for the study of their pharmacodynamic material basis.展开更多
The customer driven dynamic global market and geographical distribution of collaborating partners bring new challenges to the development of quality assurance information system (QAIS) for agile manufacturing. With re...The customer driven dynamic global market and geographical distribution of collaborating partners bring new challenges to the development of quality assurance information system (QAIS) for agile manufacturing. With recent dramatic advances in information technology, firstly the requirements of QAIS are examined in agile manufacturing environment, then a new implementation framework of a distributed QAIS is presented, where a deve loping environment of QAIS is established and some critical techniques are studied. Finally a prototype system based on world wide web (WWW) is accomplished.展开更多
This paper focuses on a strategic improving quality of"high quality assurance CAE (computer aided engineering) analysis model" to be used in development design. The authors present a case oftransaxle oil seal leak...This paper focuses on a strategic improving quality of"high quality assurance CAE (computer aided engineering) analysis model" to be used in development design. The authors present a case oftransaxle oil seal leakage in automotive drive trains, a technical reliability problem that generates bottlenecks for auto manufacturers around the world. The application of this model is used to analyze cavitation caused by the metal particles (foreign matter) generated through transaxle wear. This analyzing method primarily uses numerical simulation (CAE) to clarify the technological mechanism generating oil leaks as a result of foreign metallic substances entering oil seals in the drive train. Quality improvement using this CAE analyzing method was verified by successfully applying it to the technological problem of development design bottlenecks at auto manufacturers.展开更多
Quality assurance (QA) and quality control (QC) are fundamental aspects of any laboratory measurement. However, in comparison with other medical disciplines, the need for QA and QC in laboratory andrology has been...Quality assurance (QA) and quality control (QC) are fundamental aspects of any laboratory measurement. However, in comparison with other medical disciplines, the need for QA and QC in laboratory andrology has been recognized only recently. Furthermore, there is evidence that the effort required to undertake QA and QC has not been wholly welcomed by some clinicians. Nevertheless, accrediting bodies and regulatory authorities increasingly require evidence that laboratories have effective QA and QC measures in place because both are central to the quality management processes. Following the publication of the 5th edition of the World Health Organization Laboratory Manual, existing QA and QC systems will need to be updated to take into account some of the methodological changes recommended by the manual. Three of these are discussed in this commentary; they relate to: (i) the move to infer semen volume from its weight; (ii) the re-classification of sperm motility grades from four to three; and (iii) the publication of a lower reference limit for morphology of 4% (with a corresponding 95% confidence interval of 3%-4%). The importance of QA and QC in all laboratory tests, including up and coming new tests to assess sperm DNA integrity, is discussed. The need for adequate initial training and continuing professional development programmes to support laboratory scientists performing andrology is also described.展开更多
A mobile C-band dual polarimetric weather radar J type (PCDJ), which adopts simultaneous transmission and simultaneous reception (STSR) of horizontally and vertically polarized signals, was first developed in Chin...A mobile C-band dual polarimetric weather radar J type (PCDJ), which adopts simultaneous transmission and simultaneous reception (STSR) of horizontally and vertically polarized signals, was first developed in China in 2008. It was deployed in the radar observation plan in the South China Heavy Rainfall Experiment (SCHeREX) in the summer of 2008 and 2009, as well as in Tropical Western Pacific Ocean Observation Experiments and Research on the Predictability of High Impact Weather Events from 2008 to 2010 in China (TWPOR). Using the observation data collected in these experiments, the radar systematic error and its sources were analyzed in depth. Meanwhile an algorithm that can smooth differential propagation phase (~Dp) for estimating the high-resolution specific differential phase (KDP) was developed. After attenuation correction of reflectivity in horizontal polarization (ZH) and differential reflectivity (ZDR) of PCDJ radar by means of KDP, the data quality was improved significantly. Using quality-controlled radar data, quantitative rainfall estimation was performed, and the resutls were compared with rain-gauge measurements. A synthetic ZH /KDp-based method was analyzed. The results the traditional ZH-based method when the rain suggest that the synthetic method has the advantage over rate is 〉5 mm h^-1. The more intensive the rain rates, the higher accuracy of the estimation.展开更多
This paper describes the development and challenge of HIV/AIDS testing laboratory network and quality assurance system in China. At present,the HIV/AIDS testing laboratories includes three classes,the National AIDS Re...This paper describes the development and challenge of HIV/AIDS testing laboratory network and quality assurance system in China. At present,the HIV/AIDS testing laboratories includes three classes,the National AIDS Reference Laboratory,HIV/AIDS confirmatory laboratories and HIV/AIDS screening laboratories. All of them are accredited by the health authorities,and each class of laboratories take charge of their function strictly according to the "National Management of HIV/AIDS Detection (2006)". A complete quality assurance and quality control system for HIV/AIDS testing has been developed,which includes technical training,strict laboratory monitoring and approval,examination or proficiency testing on HIV/AIDS detection,and quality evaluation and supervision of HIV/AIDS diagnostic kits. Besides conduct the routine anti-HIV antibody test,more and more laboratories began to conduct other tests,such as CD4+ T lymphocyte cell counting,HIV viral load,HIV DNA PCR,genotyping,drug resistance,and HIV-1 recent infection test. The primary challenges faced by the HIV/AIDS testing laboratory network are in the areas of laboratory management and quality control. For example,the provincial PT program is inefficient,the internal quality control is conducted perfunctorily,personnel training can not met the needs of the workplace,which need to be improved.展开更多
Aerospace manufacturing SMEs are continuously facing the challenge on managing their supply chain and complying with the aerospace manufacturing quality standard requirement due to their lack of resources and the natu...Aerospace manufacturing SMEs are continuously facing the challenge on managing their supply chain and complying with the aerospace manufacturing quality standard requirement due to their lack of resources and the nature of business. In this paper, the ERP system based approach is presented to quality control and assurance work in light of seamless integration of in-process production data and information internally and therefore managing suppliers more effectively and efficiently. The Aerospace Manufacturing Quality Assurance Standard (BS/EN9100) is one of the most recognised and essential protocols for developing the industry-operated-and-driven quality assurance systems. The research investigates using the ERP based system as an enabler to implement BS/EN9100 quality management system at manufacturing SMEs and the associated implementation and application perspectives. An application case study on a manufacturing SME is presented by using the SAP based implementation, which helps fiarther evaluate and validate the approach and application system development.展开更多
Since each rock joint is unique by nature,the utilization of replicas in direct shear testing is required to carry out experimental parameter studies.However,information about the ability of the replicas to simulate t...Since each rock joint is unique by nature,the utilization of replicas in direct shear testing is required to carry out experimental parameter studies.However,information about the ability of the replicas to simulate the shear mechanical behavior of the rock joint and their dispersion in direct shear testing is lacking.With the aim to facilitate generation of high-quality direct shear test data from replicas,a novel component in the testing procedure is introduced by presenting two parameters for geometric quality assurance.The parameters are derived from surface comparisons of three-dimensional(3D)scanning data of the rock joint and its replicas.The first parameter,smf,captures morphological deviations between the replica and the rock joint surfaces.smf is derived as the standard deviation of the deviations between the coordinate points of the replica and the rock joint.Four sources of errors introduced in the replica manufacturing process employed in this study could be identified.These errors could be minimized,yielding replicas with smf0.06 mm.The second parameter is a vector,VHp100,which describes deviations with respect to the shear direction.It is the projection of the 100 mm long normal vector of the best-fit plane of the replica joint surface to the corresponding plane of the rock joint.VHp100was found to be less than or equal to 0.36 mm in this study.Application of these two geometric quality assurance parameters demonstrates that it is possible to manufacture replicas with high geometric similarity to the rock joint.In a subsequent paper(part 2),smf and VHp100 are incorporated in a novel quality assurance method,in which the parameters shall be evaluated prior to direct shear testing.Replicas having parameter values below established thresholds shall have a known and narrow dispersion and imitate the shear mechanical behavior of the rock joint.展开更多
Improving the quality assurance (QA) processes and acquiring accreditation are top priorities for academic programs. The learning outcomes (LOs)assessment and continuous quality improvement represent core components ...Improving the quality assurance (QA) processes and acquiring accreditation are top priorities for academic programs. The learning outcomes (LOs)assessment and continuous quality improvement represent core components ofthe quality assurance system (QAS). Current assessment methods suffer deficiencies related to accuracy and reliability, and they lack well-organized processes forcontinuous improvement planning. Moreover, the absence of automation, andintegration in QA processes forms a major obstacle towards developing efficientquality system. There is a pressing need to adopt security protocols that providerequired security services to safeguard the valuable information processed byQAS as well. This research proposes an effective methodology for LOs assessment and continuous improvement processes. The proposed approach ensuresmore accurate and reliable LOs assessment results and provides systematic wayfor utilizing those results in the continuous quality improvement. This systematicand well-specified QA processes were then utilized to model and implement automated and secure QAS that efficiently performs quality-related processes. Theproposed system adopts two security protocols that provide confidentiality, integrity, and authentication for quality data and reports. The security protocols avoidthe source repudiation, which is important in the quality reporting system. This isachieved through implementing powerful cryptographic algorithms. The QASenables efficient data collection and processing required for analysis and interpretation. It also prepares for the development of datasets that can be used in futureartificial intelligence (AI) researches to support decision making and improve thequality of academic programs. The proposed approach is implemented in a successful real case study for a computer science program. The current study servesscientific programs struggling to achieve academic accreditation, and gives rise tofully automating and integrating the QA processes and adopting modern AI andsecurity technologies to develop effective QAS.展开更多
Objectives: To classify community pharmacies (CPs) in Riyadh, Saudi Arabia, in terms of the quality of medicines sold by them, using?the lot quality assurance sampling (LQAS) technique with a predefined threshold. Met...Objectives: To classify community pharmacies (CPs) in Riyadh, Saudi Arabia, in terms of the quality of medicines sold by them, using?the lot quality assurance sampling (LQAS) technique with a predefined threshold. Methods: Riyadh CPs were divided into 2 categories (“lots” for the purpose of LQAS), i.e., chain and independent CPs. Upper and lower rate thresholds for CPs that sell low-quality medicines were predefined as 20% and 5%, respectively. Consumer and provider risks were predefined as 0.05 and 0.10, respectively. The calculated number of randomly selected CPs required in each lot was 36;then, sale of low-quality medicines in >3 CPs implies a prevalence of >20% of such CPs according to LQAS. A randomly selected brand of amoxicillin (selected as a quality indicator of medicines because it is both widely counterfeited and heat-sensitive) was purchased from each pharmacy by a “mystery shopper”, checked for authenticity, and analyzed for drug content and content uniformity using a validated HPLC method. Results: Substandard amoxicillin was purchased in 9 pharmacies (4 chains and 5 independent). Both lots were thus rejected as unacceptable, which may indicate that consumers in Riyadh are at risk of purchasing substandard medicines at CPs. Conclusions: The quality of medicines sold in CPs in Riyadh did not meet our acceptability criterion, and appropriate intervention by decision makers is recommended. LQAS proved to be a practical, economical, and statistically valid sampling method for surveying the quality of medicines. It should enable decision makers to allocate resources for improvement more efficiently.展开更多
Each rock joint is unique by nature which means that utilization of replicas in direct shear tests is required in experimental parameter studies.However,a method to acquire knowledge about the ability of the replicas ...Each rock joint is unique by nature which means that utilization of replicas in direct shear tests is required in experimental parameter studies.However,a method to acquire knowledge about the ability of the replicas to imitate the shear mechanical behavior of the rock joint and their dispersion in direct shear testing is lacking.In this study,a novel method is presented for geometric quality assurance of replicas.The aim is to facilitate generation of high-quality direct shear testing data as a prerequisite for reliable subsequent analyses of the results.In Part 1 of this study,two quality assurance parameters,smf and V_(Hp100),are derived and their usefulness for evaluation of geometric deviations,i.e.geometric reproducibility,is shown.In Part 2,the parameters are validated by showing a correlation between the parameters and the shear mechanical behavior,which qualifies the parameters for usage in the quality assurance method.Unique results from direct shear tests presenting comparisons between replicas and the rock joint show that replicas fulfilling proposed threshold values of σ_(mf)<0.06 mm and|V_(Hp100)|<0.2 mm have a narrow dispersion and imitate the shear mechanical behavior of the rock joint in all aspects apart from having a slightly lower peak shear strength.The wear in these replicas,which have similar morphology as the rock joint,is in the same areas as in the rock joint.The wear is slightly larger in the rock joint and therefore the discrepancy in peak shear strength derives from differences in material properties,possibly from differences in toughness.It is shown by application of the suggested method that the quality assured replicas manufactured following the process employed in this study phenomenologically capture the shear strength characteristics,which makes them useful in parameter studies.展开更多
A systematic method was proposed to estimate the occurrence probability of defective piles(OPDP) from a site according to quality assurance inspection. The OPDP was firstly suggested as the criterion to weight the per...A systematic method was proposed to estimate the occurrence probability of defective piles(OPDP) from a site according to quality assurance inspection. The OPDP was firstly suggested as the criterion to weight the performance of a pile foundation. Its prior distribution and updating distribution were deduced to follow Beta distributions. To calibrate the OPDP, a dynamic estimation model was established according to the relationships between prior mean and variance and updating mean and variance. Finally, a reliability-control method dealing with uncertainties arising from quality assurance inspection was formalized to judge whether all the bored piles from a site can be accepted. It is exemplified that the OPDP can be substantially improved when more definite prior information and sampling formation become available. For the example studied herein, the Bayesian estimator of updating variance for OPDP is reduced from 0.0037 to 0.0014 for the first inspection, from 0.0014 to 0.0009 for the second inspection, and with less uncertainty by incorporating experience information.展开更多
Continuously improving the internal quality assurance system and promoting the innovative development of higher vocational education is a challenge that every higher vocational institution must solve on the road of di...Continuously improving the internal quality assurance system and promoting the innovative development of higher vocational education is a challenge that every higher vocational institution must solve on the road of diagnosis and improvement.To address the current dilemma of building internal quality assurance systems in higher education institutions,this study utilizes a case study approach.This study takes Jingzhou Vocational and Technical College as the research object for research.Conclusion:The excellent diagnosis and reform model and the effectiveness of diagnosis and reform in this school can provide new strategic ideas for the practice of diagnosis and reform for the high-quality development of higher education in Hubei.展开更多
The radiation dose received by patients undergoing chest radiography was included. 200 patients who attended these investigations in 10 hospitals in Iran were randomly selected from all ages groups and both female and...The radiation dose received by patients undergoing chest radiography was included. 200 patients who attended these investigations in 10 hospitals in Iran were randomly selected from all ages groups and both female and male. Critically ill patients were excluded. This paper presents the work, which was implemented on 200 patients and evaluated using the entrance skin dose (ESD) in the posterior anterior (PA) chest projection measured directly at the center of the X-ray field. In addition, the machine room, and dark room .parameters, as well as work practices and repeat rates were studied. The quality control (QC) parameters and the ESD before and after QC were evaluated utilizing an anthropomorphic phantom to define the optimal exposure condition at all hospitals. This research shows that after using the QC parameters and after optimization of the exposure conditions, the ESD was decreased by 42% on average. Also the qua/ity of the radiographs generally increased. The reported method is easily implemented in any clinical situation where optimization of chest radiography is needed.展开更多
To be a worldwide competitor, enterprise needs to e va luate and select its supplier carefully. Generally, to evaluate a supplier, the evaluating effort is focused on the purchase price, delivery time, product quali t...To be a worldwide competitor, enterprise needs to e va luate and select its supplier carefully. Generally, to evaluate a supplier, the evaluating effort is focused on the purchase price, delivery time, product quali ty, etc. The vendors’ quality assurance is seldom considered. However, it reflec ts the ability that a vendor can provide high quality but low cost products cont inuously and stably. In this paper, with the study on evaluation of supplier’s q uality assurance system, a set of methods and indices to supplier’s quality assu rance evaluation is introduced. The indices construct an index system, which is based on the ISO9000 series standards. According to the problem’s character and the requirement of evaluation, all the evaluation indices are set off to three k inds: general index, functional index and protective index. And the evaluation m ethod combines quantitative analysis with qualitative analysis. Firstly, a sensi tive factor model is constructed to estimate the contribution of factors that ha ve key effect on synthetic evaluation in supplier’s quality system. Then, those suppliers having low evaluating value are rejected. Secondly, fuzzy logic is int roduced to evaluate other suppliers synthetically. The rest suppliers are compar able. So, supplier’s quality assurance system can be evaluated in quantity. Afte r unification works, the evaluated suppliers can be ranked. And the best vendor can be selected out intuitively.展开更多
As developing countries become more involved in the international chemical trade, they must adhere to certain requirements for importation of their chemicals into foreign countries. These developing countries will be ...As developing countries become more involved in the international chemical trade, they must adhere to certain requirements for importation of their chemicals into foreign countries. These developing countries will be required to provide basic safety information on their chemical products, including data developed from chemical and toxicologic testing. These data must be developed in accordance with the national requirements of the importing country. Many importing countries have adopted the OECD Test Guidelines and the OECD Principles of Good Laboratory Practice (GLP) as primary guidance to assure the quality of laboratory data. These procedures provide a basis for internationally acceptable data. Several countries have incorporated many of these provisions into their national laws or administrative procedures. These procedures describe the process of documenting the conduct of laboratory studies, including recording of data, reporting of study results, and storage of data gathered. This process is intended to assure the quality and integrity of the data so that, if required, the study can be reconstructed by an auditor or an inspector. Details of these procedures and their applicability to the international chemical trade are discussed. 1989 Academic Press, Inc.展开更多
Objective:The main purpose of this work was to present a Z-phantom manufactured in home (at National Cancer Institute Cairo University) and it's use in a simple way to check the accuracy of the computed-tomography...Objective:The main purpose of this work was to present a Z-phantom manufactured in home (at National Cancer Institute Cairo University) and it's use in a simple way to check the accuracy of the computed-tomography (CT) table movement and CT gantry tilt, also the other general quality control (QC) tests of the CT simulator used at radiotherapy department. Methods:The laser phantom was used to check the external mobile laser position accuracy, for internal image indicator laser beam (light field) the coincidence between light field and radiation exposure at CT simulator was checked using X-Omat ready back film. The Z-phantom was used to check the slice thickness and the table movement and so the gantry tilts. The image quality testes were checked using the CT image quality phantom. TLDs were inserted to the Cicil phantom at the center of each scan volume to estimate the patient dose. Results:The results showed that the difference in the fixed distance between the external mobile laser and the internal image indicator laser beam was less than ± 1 mm; the orientation of the two mobile lateral lasers was coincident. The mechanical movement and the image quality of the CT simulator were within the tolerances and the results were 0.5 mm, 0.2% and 0.6% for the mechanical movement, noise and image uniformity respectively. Conclusion:A CT simulator with a good performance is important for the radiotherapy treatment planning specially with the extremely revolution in radiotherapy techniques, also a rotten quality assurance (QA) program is very important to be shore about the reproducibility of the CT performance. The use of Z-phantom to check the gantry tilt and the table movement is faster than the use of ready back films in these tests.展开更多
This paper presents a broad range of suggestions on the concept of quality-assured industry-oriented higher education in software engineering,a central theme of the annual CEISIE(CEISEE this year) workshops since the ...This paper presents a broad range of suggestions on the concept of quality-assured industry-oriented higher education in software engineering,a central theme of the annual CEISIE(CEISEE this year) workshops since the first one held in Harbin,China,in 2005.It draws on the lessons of collaborative experiences involving academics and industrialists from Europe and China.These experiences make the case for a strong role for software industryoriented higher education in the production of the software architects,developers and engineers required for the future.展开更多
基金2023 Annual Funded Projects for Educational Scientific Research at Xuzhou University of Technology“Construction and Practice of the Quality Assurance System for Education and Teaching in Applied Undergraduate Colleges under the Background of Digitalization”(YGJ2345)。
文摘This paper discusses the optimization strategy of education and teaching quality assurance systems in applied colleges and universities under the background of digital intelligence.It first summarizes the relevant theories of digital intelligence transformation and analyzes the impact of digital intelligence transformation on higher education.Secondly,this paper puts forward the principles of constructing the quality assurance system of applied colleges,including strengthening the quality assurance consciousness,improving teachers’digital literacy,and implementing digital intelligence governance.From the practical perspective,this paper expounds on strategies such as optimizing educational teaching resource allocation,constructing a diversified evaluation system of teaching quality,strengthening the construction and training of teaching staff,and innovating teaching management methods.Specific optimization measures are put forward,such as improving policies,regulations,and system guarantees,strengthening cooperation between schools and enterprises,integrating industry,school,and research,building an educational information platform,and improving the monitoring and feedback mechanism of educational quality.
基金supported by the key project at the central government level:The ability establishment of sustainable use for valuable Chinese medicine resources(Grant number 2060302)the National Natural Science Foundation of China(Grant number 82373982,82173929).
文摘Background:Rosa chinensis Jacq.and Rosa rugosa Thunb.are not only of ornamental value,but also edible flowers and the flower buds have been listed in the Chinese Pharmacopoeia as traditional medicines.The two plants have some differences in efficacy,but the flower buds are easily confused for similar traits.In addition,large-scale cultivation of ornamental rose flowers may lead to a decrease in the effective components of medicinal roses.Therefore,it is necessary to study the chemical composition and make quality evaluation of Rosae Chinensis Flos(Yueji)and Rosae Rugosae Flos(Meigui).Methods:In this study,40 batches of samples including Meigui and Yueji from different regions in China were collected to establish high-performance liquid chromatography fingerprints.Then,the fingerprints data was analyzed using principal component analysis,hierarchical cluster analysis,and partial least squares discriminant analysis analysis chemometrics to obtain information on intergroup differences,and non-targeted metabolomic techniques were applied to identify and compare chemical compositions of samples which were chosen from groups with large differences.Differential compounds were screened by orthogonal partial least-squares discriminant analysis and S-plot,and finally multi-component quantification was performed to comprehensively evaluate the quality of Yueji and Meigui.Results:The similarity between the fingerprints of 40 batches roses and the reference print R was 0.73 to 0.93,indicating that there were similarities and differences between the samples.Through principal component analysis and hierarchical cluster analysis of fingerprints data,the samples from different origins and varieties were intuitively divided into four groups.Partial least-squares discriminant analysis analysis showed that Meigui and Yueji cluster into two categories and the model was reliable.A total of 89 compounds were identified by high resolution mass spectrometry,mainly were flavonoids and flavonoid glycosides,as well as phenolic acids.Eight differential components were screened out by orthogonal partial least-squares discriminant analysis and S-plot analysis.Quantitative analyses of the eight compounds,including gallic acid,ellagic acid,hyperoside,isoquercitrin,etc.,showed that Yueji was generally richer in phenolic acids and flavonoids than Meigui,and the quality of Yueji from Shandong and Hebei was better.It is worth noting that Xinjiang rose is rich in various components,which is worth focusing on more in-depth research.Conclusion:In this study,the fingerprints of Meigui and Yueji were established.The chemical components information of roses was further improved based on non-targeted metabolomics and mass spectrometry technology.At the same time,eight differential components of Meigui and Yueji were screened out and quantitatively analyzed.The research results provided a scientific basis for the quality control and rational development and utilization of Rosae Chinensis Flos and Rosae Rugosae Flos,and also laid a foundation for the study of their pharmacodynamic material basis.
文摘The customer driven dynamic global market and geographical distribution of collaborating partners bring new challenges to the development of quality assurance information system (QAIS) for agile manufacturing. With recent dramatic advances in information technology, firstly the requirements of QAIS are examined in agile manufacturing environment, then a new implementation framework of a distributed QAIS is presented, where a deve loping environment of QAIS is established and some critical techniques are studied. Finally a prototype system based on world wide web (WWW) is accomplished.
文摘This paper focuses on a strategic improving quality of"high quality assurance CAE (computer aided engineering) analysis model" to be used in development design. The authors present a case oftransaxle oil seal leakage in automotive drive trains, a technical reliability problem that generates bottlenecks for auto manufacturers around the world. The application of this model is used to analyze cavitation caused by the metal particles (foreign matter) generated through transaxle wear. This analyzing method primarily uses numerical simulation (CAE) to clarify the technological mechanism generating oil leaks as a result of foreign metallic substances entering oil seals in the drive train. Quality improvement using this CAE analyzing method was verified by successfully applying it to the technological problem of development design bottlenecks at auto manufacturers.
文摘Quality assurance (QA) and quality control (QC) are fundamental aspects of any laboratory measurement. However, in comparison with other medical disciplines, the need for QA and QC in laboratory andrology has been recognized only recently. Furthermore, there is evidence that the effort required to undertake QA and QC has not been wholly welcomed by some clinicians. Nevertheless, accrediting bodies and regulatory authorities increasingly require evidence that laboratories have effective QA and QC measures in place because both are central to the quality management processes. Following the publication of the 5th edition of the World Health Organization Laboratory Manual, existing QA and QC systems will need to be updated to take into account some of the methodological changes recommended by the manual. Three of these are discussed in this commentary; they relate to: (i) the move to infer semen volume from its weight; (ii) the re-classification of sperm motility grades from four to three; and (iii) the publication of a lower reference limit for morphology of 4% (with a corresponding 95% confidence interval of 3%-4%). The importance of QA and QC in all laboratory tests, including up and coming new tests to assess sperm DNA integrity, is discussed. The need for adequate initial training and continuing professional development programmes to support laboratory scientists performing andrology is also described.
基金funded by National Natural Science Foundation of China (Grant Nos. 40975013 and 40975014)Chinese Academy of Meteorological Sciences (CAMS) basic scientific and operational project:Observation and retrieval methods of microphysics and dynamic parameters of cloud and precipitation with multi-wavelength Remote Sensing,SCHeREX and TWPOR
文摘A mobile C-band dual polarimetric weather radar J type (PCDJ), which adopts simultaneous transmission and simultaneous reception (STSR) of horizontally and vertically polarized signals, was first developed in China in 2008. It was deployed in the radar observation plan in the South China Heavy Rainfall Experiment (SCHeREX) in the summer of 2008 and 2009, as well as in Tropical Western Pacific Ocean Observation Experiments and Research on the Predictability of High Impact Weather Events from 2008 to 2010 in China (TWPOR). Using the observation data collected in these experiments, the radar systematic error and its sources were analyzed in depth. Meanwhile an algorithm that can smooth differential propagation phase (~Dp) for estimating the high-resolution specific differential phase (KDP) was developed. After attenuation correction of reflectivity in horizontal polarization (ZH) and differential reflectivity (ZDR) of PCDJ radar by means of KDP, the data quality was improved significantly. Using quality-controlled radar data, quantitative rainfall estimation was performed, and the resutls were compared with rain-gauge measurements. A synthetic ZH /KDp-based method was analyzed. The results the traditional ZH-based method when the rain suggest that the synthetic method has the advantage over rate is 〉5 mm h^-1. The more intensive the rain rates, the higher accuracy of the estimation.
基金MOH Program on Applied Research in the Prevention and Treatment of AIDS (WA 2003-17)
文摘This paper describes the development and challenge of HIV/AIDS testing laboratory network and quality assurance system in China. At present,the HIV/AIDS testing laboratories includes three classes,the National AIDS Reference Laboratory,HIV/AIDS confirmatory laboratories and HIV/AIDS screening laboratories. All of them are accredited by the health authorities,and each class of laboratories take charge of their function strictly according to the "National Management of HIV/AIDS Detection (2006)". A complete quality assurance and quality control system for HIV/AIDS testing has been developed,which includes technical training,strict laboratory monitoring and approval,examination or proficiency testing on HIV/AIDS detection,and quality evaluation and supervision of HIV/AIDS diagnostic kits. Besides conduct the routine anti-HIV antibody test,more and more laboratories began to conduct other tests,such as CD4+ T lymphocyte cell counting,HIV viral load,HIV DNA PCR,genotyping,drug resistance,and HIV-1 recent infection test. The primary challenges faced by the HIV/AIDS testing laboratory network are in the areas of laboratory management and quality control. For example,the provincial PT program is inefficient,the internal quality control is conducted perfunctorily,personnel training can not met the needs of the workplace,which need to be improved.
基金support for this research (R85169) from Mollart Engineering Ltd
文摘Aerospace manufacturing SMEs are continuously facing the challenge on managing their supply chain and complying with the aerospace manufacturing quality standard requirement due to their lack of resources and the nature of business. In this paper, the ERP system based approach is presented to quality control and assurance work in light of seamless integration of in-process production data and information internally and therefore managing suppliers more effectively and efficiently. The Aerospace Manufacturing Quality Assurance Standard (BS/EN9100) is one of the most recognised and essential protocols for developing the industry-operated-and-driven quality assurance systems. The research investigates using the ERP based system as an enabler to implement BS/EN9100 quality management system at manufacturing SMEs and the associated implementation and application perspectives. An application case study on a manufacturing SME is presented by using the SAP based implementation, which helps fiarther evaluate and validate the approach and application system development.
文摘Since each rock joint is unique by nature,the utilization of replicas in direct shear testing is required to carry out experimental parameter studies.However,information about the ability of the replicas to simulate the shear mechanical behavior of the rock joint and their dispersion in direct shear testing is lacking.With the aim to facilitate generation of high-quality direct shear test data from replicas,a novel component in the testing procedure is introduced by presenting two parameters for geometric quality assurance.The parameters are derived from surface comparisons of three-dimensional(3D)scanning data of the rock joint and its replicas.The first parameter,smf,captures morphological deviations between the replica and the rock joint surfaces.smf is derived as the standard deviation of the deviations between the coordinate points of the replica and the rock joint.Four sources of errors introduced in the replica manufacturing process employed in this study could be identified.These errors could be minimized,yielding replicas with smf0.06 mm.The second parameter is a vector,VHp100,which describes deviations with respect to the shear direction.It is the projection of the 100 mm long normal vector of the best-fit plane of the replica joint surface to the corresponding plane of the rock joint.VHp100was found to be less than or equal to 0.36 mm in this study.Application of these two geometric quality assurance parameters demonstrates that it is possible to manufacture replicas with high geometric similarity to the rock joint.In a subsequent paper(part 2),smf and VHp100 are incorporated in a novel quality assurance method,in which the parameters shall be evaluated prior to direct shear testing.Replicas having parameter values below established thresholds shall have a known and narrow dispersion and imitate the shear mechanical behavior of the rock joint.
基金Author extends his appreciation to the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University for funding and supporting this work through Graduate Student Research Support Program.
文摘Improving the quality assurance (QA) processes and acquiring accreditation are top priorities for academic programs. The learning outcomes (LOs)assessment and continuous quality improvement represent core components ofthe quality assurance system (QAS). Current assessment methods suffer deficiencies related to accuracy and reliability, and they lack well-organized processes forcontinuous improvement planning. Moreover, the absence of automation, andintegration in QA processes forms a major obstacle towards developing efficientquality system. There is a pressing need to adopt security protocols that providerequired security services to safeguard the valuable information processed byQAS as well. This research proposes an effective methodology for LOs assessment and continuous improvement processes. The proposed approach ensuresmore accurate and reliable LOs assessment results and provides systematic wayfor utilizing those results in the continuous quality improvement. This systematicand well-specified QA processes were then utilized to model and implement automated and secure QAS that efficiently performs quality-related processes. Theproposed system adopts two security protocols that provide confidentiality, integrity, and authentication for quality data and reports. The security protocols avoidthe source repudiation, which is important in the quality reporting system. This isachieved through implementing powerful cryptographic algorithms. The QASenables efficient data collection and processing required for analysis and interpretation. It also prepares for the development of datasets that can be used in futureartificial intelligence (AI) researches to support decision making and improve thequality of academic programs. The proposed approach is implemented in a successful real case study for a computer science program. The current study servesscientific programs struggling to achieve academic accreditation, and gives rise tofully automating and integrating the QA processes and adopting modern AI andsecurity technologies to develop effective QAS.
文摘Objectives: To classify community pharmacies (CPs) in Riyadh, Saudi Arabia, in terms of the quality of medicines sold by them, using?the lot quality assurance sampling (LQAS) technique with a predefined threshold. Methods: Riyadh CPs were divided into 2 categories (“lots” for the purpose of LQAS), i.e., chain and independent CPs. Upper and lower rate thresholds for CPs that sell low-quality medicines were predefined as 20% and 5%, respectively. Consumer and provider risks were predefined as 0.05 and 0.10, respectively. The calculated number of randomly selected CPs required in each lot was 36;then, sale of low-quality medicines in >3 CPs implies a prevalence of >20% of such CPs according to LQAS. A randomly selected brand of amoxicillin (selected as a quality indicator of medicines because it is both widely counterfeited and heat-sensitive) was purchased from each pharmacy by a “mystery shopper”, checked for authenticity, and analyzed for drug content and content uniformity using a validated HPLC method. Results: Substandard amoxicillin was purchased in 9 pharmacies (4 chains and 5 independent). Both lots were thus rejected as unacceptable, which may indicate that consumers in Riyadh are at risk of purchasing substandard medicines at CPs. Conclusions: The quality of medicines sold in CPs in Riyadh did not meet our acceptability criterion, and appropriate intervention by decision makers is recommended. LQAS proved to be a practical, economical, and statistically valid sampling method for surveying the quality of medicines. It should enable decision makers to allocate resources for improvement more efficiently.
文摘Each rock joint is unique by nature which means that utilization of replicas in direct shear tests is required in experimental parameter studies.However,a method to acquire knowledge about the ability of the replicas to imitate the shear mechanical behavior of the rock joint and their dispersion in direct shear testing is lacking.In this study,a novel method is presented for geometric quality assurance of replicas.The aim is to facilitate generation of high-quality direct shear testing data as a prerequisite for reliable subsequent analyses of the results.In Part 1 of this study,two quality assurance parameters,smf and V_(Hp100),are derived and their usefulness for evaluation of geometric deviations,i.e.geometric reproducibility,is shown.In Part 2,the parameters are validated by showing a correlation between the parameters and the shear mechanical behavior,which qualifies the parameters for usage in the quality assurance method.Unique results from direct shear tests presenting comparisons between replicas and the rock joint show that replicas fulfilling proposed threshold values of σ_(mf)<0.06 mm and|V_(Hp100)|<0.2 mm have a narrow dispersion and imitate the shear mechanical behavior of the rock joint in all aspects apart from having a slightly lower peak shear strength.The wear in these replicas,which have similar morphology as the rock joint,is in the same areas as in the rock joint.The wear is slightly larger in the rock joint and therefore the discrepancy in peak shear strength derives from differences in material properties,possibly from differences in toughness.It is shown by application of the suggested method that the quality assured replicas manufactured following the process employed in this study phenomenologically capture the shear strength characteristics,which makes them useful in parameter studies.
基金Project(51278216) supported by the National Natural Science Foundation of ChinaProject(2013BS010) supported by Henan University of Technology Fund for High-level Talent,China
文摘A systematic method was proposed to estimate the occurrence probability of defective piles(OPDP) from a site according to quality assurance inspection. The OPDP was firstly suggested as the criterion to weight the performance of a pile foundation. Its prior distribution and updating distribution were deduced to follow Beta distributions. To calibrate the OPDP, a dynamic estimation model was established according to the relationships between prior mean and variance and updating mean and variance. Finally, a reliability-control method dealing with uncertainties arising from quality assurance inspection was formalized to judge whether all the bored piles from a site can be accepted. It is exemplified that the OPDP can be substantially improved when more definite prior information and sampling formation become available. For the example studied herein, the Bayesian estimator of updating variance for OPDP is reduced from 0.0037 to 0.0014 for the first inspection, from 0.0014 to 0.0009 for the second inspection, and with less uncertainty by incorporating experience information.
文摘Continuously improving the internal quality assurance system and promoting the innovative development of higher vocational education is a challenge that every higher vocational institution must solve on the road of diagnosis and improvement.To address the current dilemma of building internal quality assurance systems in higher education institutions,this study utilizes a case study approach.This study takes Jingzhou Vocational and Technical College as the research object for research.Conclusion:The excellent diagnosis and reform model and the effectiveness of diagnosis and reform in this school can provide new strategic ideas for the practice of diagnosis and reform for the high-quality development of higher education in Hubei.
文摘The radiation dose received by patients undergoing chest radiography was included. 200 patients who attended these investigations in 10 hospitals in Iran were randomly selected from all ages groups and both female and male. Critically ill patients were excluded. This paper presents the work, which was implemented on 200 patients and evaluated using the entrance skin dose (ESD) in the posterior anterior (PA) chest projection measured directly at the center of the X-ray field. In addition, the machine room, and dark room .parameters, as well as work practices and repeat rates were studied. The quality control (QC) parameters and the ESD before and after QC were evaluated utilizing an anthropomorphic phantom to define the optimal exposure condition at all hospitals. This research shows that after using the QC parameters and after optimization of the exposure conditions, the ESD was decreased by 42% on average. Also the qua/ity of the radiographs generally increased. The reported method is easily implemented in any clinical situation where optimization of chest radiography is needed.
文摘To be a worldwide competitor, enterprise needs to e va luate and select its supplier carefully. Generally, to evaluate a supplier, the evaluating effort is focused on the purchase price, delivery time, product quali ty, etc. The vendors’ quality assurance is seldom considered. However, it reflec ts the ability that a vendor can provide high quality but low cost products cont inuously and stably. In this paper, with the study on evaluation of supplier’s q uality assurance system, a set of methods and indices to supplier’s quality assu rance evaluation is introduced. The indices construct an index system, which is based on the ISO9000 series standards. According to the problem’s character and the requirement of evaluation, all the evaluation indices are set off to three k inds: general index, functional index and protective index. And the evaluation m ethod combines quantitative analysis with qualitative analysis. Firstly, a sensi tive factor model is constructed to estimate the contribution of factors that ha ve key effect on synthetic evaluation in supplier’s quality system. Then, those suppliers having low evaluating value are rejected. Secondly, fuzzy logic is int roduced to evaluate other suppliers synthetically. The rest suppliers are compar able. So, supplier’s quality assurance system can be evaluated in quantity. Afte r unification works, the evaluated suppliers can be ranked. And the best vendor can be selected out intuitively.
文摘As developing countries become more involved in the international chemical trade, they must adhere to certain requirements for importation of their chemicals into foreign countries. These developing countries will be required to provide basic safety information on their chemical products, including data developed from chemical and toxicologic testing. These data must be developed in accordance with the national requirements of the importing country. Many importing countries have adopted the OECD Test Guidelines and the OECD Principles of Good Laboratory Practice (GLP) as primary guidance to assure the quality of laboratory data. These procedures provide a basis for internationally acceptable data. Several countries have incorporated many of these provisions into their national laws or administrative procedures. These procedures describe the process of documenting the conduct of laboratory studies, including recording of data, reporting of study results, and storage of data gathered. This process is intended to assure the quality and integrity of the data so that, if required, the study can be reconstructed by an auditor or an inspector. Details of these procedures and their applicability to the international chemical trade are discussed. 1989 Academic Press, Inc.
文摘Objective:The main purpose of this work was to present a Z-phantom manufactured in home (at National Cancer Institute Cairo University) and it's use in a simple way to check the accuracy of the computed-tomography (CT) table movement and CT gantry tilt, also the other general quality control (QC) tests of the CT simulator used at radiotherapy department. Methods:The laser phantom was used to check the external mobile laser position accuracy, for internal image indicator laser beam (light field) the coincidence between light field and radiation exposure at CT simulator was checked using X-Omat ready back film. The Z-phantom was used to check the slice thickness and the table movement and so the gantry tilts. The image quality testes were checked using the CT image quality phantom. TLDs were inserted to the Cicil phantom at the center of each scan volume to estimate the patient dose. Results:The results showed that the difference in the fixed distance between the external mobile laser and the internal image indicator laser beam was less than ± 1 mm; the orientation of the two mobile lateral lasers was coincident. The mechanical movement and the image quality of the CT simulator were within the tolerances and the results were 0.5 mm, 0.2% and 0.6% for the mechanical movement, noise and image uniformity respectively. Conclusion:A CT simulator with a good performance is important for the radiotherapy treatment planning specially with the extremely revolution in radiotherapy techniques, also a rotten quality assurance (QA) program is very important to be shore about the reproducibility of the CT performance. The use of Z-phantom to check the gantry tilt and the table movement is faster than the use of ready back films in these tests.
文摘This paper presents a broad range of suggestions on the concept of quality-assured industry-oriented higher education in software engineering,a central theme of the annual CEISIE(CEISEE this year) workshops since the first one held in Harbin,China,in 2005.It draws on the lessons of collaborative experiences involving academics and industrialists from Europe and China.These experiences make the case for a strong role for software industryoriented higher education in the production of the software architects,developers and engineers required for the future.