The whole performance of the networked control system （NCSs） depends on two interaction factors, namely the quality of control performance （QoP） and quality of network service （QoS）. So, to optimize the whole pe...The whole performance of the networked control system （NCSs） depends on two interaction factors, namely the quality of control performance （QoP） and quality of network service （QoS）. So, to optimize the whole perfor-mance of NCSs, the problem of guaranteeing QoP and QoS plays an important role in the design of NCSs. However, up to now, little work has been done in this field. In this paper, a synthesizing control model of NCSs to guarantee QoP and QoS is proposed, and a feasible condition of optimizing whole performance of NCSs is also suggested. Finally, the simulation results show that the proposed model is effective.展开更多
A simple and reliable high performance liquid chromatography （HPLC） method has been developed for the simultaneous quantification of five major bioactive components in ＇Shu-Jin- Zhi-Tong＇ capsules （SJZTC）, for t...A simple and reliable high performance liquid chromatography （HPLC） method has been developed for the simultaneous quantification of five major bioactive components in ＇Shu-Jin- Zhi-Tong＇ capsules （SJZTC）, for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC.展开更多
A rapid and effective method, solid phase extraction coupled with high performance liquid chromatography（SPE-HPLC）, was applied to the separation and analysis of ginsenosides. Waters OASIS HLB was used for concentra...A rapid and effective method, solid phase extraction coupled with high performance liquid chromatography（SPE-HPLC）, was applied to the separation and analysis of ginsenosides. Waters OASIS HLB was used for concentrating and purifying samples and Alltima C18（53 mm×7 mm, 3 μm） chromatography column was used for separating ginsenoside Rg1, Re, Rb1, Rc, Rb2 and Rd. These ginsenosides were analyzed within 20 min in our gradient elution process and the equilibrium time of the chromatography column cost only 5 min. Moreover, there was no obvious baseline drift in our experiment. This method was used to analyze the contents of ginsenosides in different ginseng products for quality control. Four ginseng products were studied, including two kinds of capsules, one kind of tablet and one kind of injection. The results show that the method developed in this paper had good accuracy, linearity and precision. Therefore, this method could be applied in quality control of ginseng products.展开更多
为提高船舶总体设计质效,本文基于船舶设计、多学科设计优化(Multi-disciplinary Design and Optimization,MDO)理论及其应用的相关资料,在梳理现阶段船舶设计理论及基本流程的基础上,分析MDO理论在指导船舶设计中应用的可行性。结果表...为提高船舶总体设计质效,本文基于船舶设计、多学科设计优化(Multi-disciplinary Design and Optimization,MDO)理论及其应用的相关资料,在梳理现阶段船舶设计理论及基本流程的基础上,分析MDO理论在指导船舶设计中应用的可行性。结果表明,在船舶设计过程中应重点关注船舶型线设计、推进系统设计及振动噪声性能控制等关键技术。通过分析上述技术方面的研究进展,并基于MDO理论提出若干关于提高船舶总体设计质效的建议,对改进船舶总体设计方法具有一定工程指导价值。展开更多
Objective:Huamaoyan Granules(HMYG)and Huamaoyan Capsules(HMYC)are Chinese patent medicines with different dosage forms of the same prescription.Due to the different preparation process,the chemical composition of thes...Objective:Huamaoyan Granules(HMYG)and Huamaoyan Capsules(HMYC)are Chinese patent medicines with different dosage forms of the same prescription.Due to the different preparation process,the chemical composition of these Chinese patent medicines varies greatly among different forms,but there were few studies on the difference comparison and quality control of them.In order to improve the effectiveness and safety in its clinical application,an idea combining high performance liquid chromatography(HPLC)and chemometrics was put forward to study the quality control of Chinese patent medicines in different dosage forms of the same prescription.Methods:The differential markers of HMYG and HMYC were explored based on HPLC fingerprint and chemometrics including orthogonal projections to latent structures-discriminant analysis(OPLS-DA),principal component analysis(PCA),and hierarchical cluster analysis(HCA).Finally,the quantitative analysis method of related components was established by HPLC.Results:A quality control method for HMYG and HMYC was established.Firstly,the chemical components of HMYG and HMYC were systematically analyzed by HPLC fingerprinting.Further exploration showed that there were 20 characteristic peaks and 57 common peaks.Then,the potential differential markers between HMYG and HMYC were explored by chemometrics,and the differential markers were screened after intersection with the 20 characteristic peaks.Finally,HPLC quantitative analysis methods for nine components were established,including seven differential markers(neochlorogenic acid,protocatechualdehyde,chlorogenic acid,cryptochlorogenic acid,caffeic acid,rosmarinic acid and salvianolic acid A).The results of HPLC quantitative analysis showed that the contents of eight components in HMYG and HMYC samples were significantly different.According to the above results,the differential markers between HMYG and HMYC screened based on HPLC fingerprint and chemometrics can effectively characterize the differences between the two dosage forms.Conclusion:The present work provides a rapid and effective method for routine quality evaluation and control of HMYG and HMYC.This work also provides feasible methods for the quality evaluation and control of Chinese patent medicines with different dosage forms of the same prescription.展开更多
文摘The whole performance of the networked control system （NCSs） depends on two interaction factors, namely the quality of control performance （QoP） and quality of network service （QoS）. So, to optimize the whole perfor-mance of NCSs, the problem of guaranteeing QoP and QoS plays an important role in the design of NCSs. However, up to now, little work has been done in this field. In this paper, a synthesizing control model of NCSs to guarantee QoP and QoS is proposed, and a feasible condition of optimizing whole performance of NCSs is also suggested. Finally, the simulation results show that the proposed model is effective.
基金was funded by a grant from the Scientific and Technological Innovation Project Foundation of Shanxi China (No. 20090321099)
文摘A simple and reliable high performance liquid chromatography （HPLC） method has been developed for the simultaneous quantification of five major bioactive components in ＇Shu-Jin- Zhi-Tong＇ capsules （SJZTC）, for the purposes of quality control of this commonly prescribed traditional Chinese medicine. Under the optimum conditions, excellent separation was achieved, and the assay was fully validated in terms of linearity, precision, repeatability, stability and accuracy. The validated method was applied successfully to the determination of the five compounds in SJZTC samples from different production batches. The HPLC method can be used as a valid analytical method to evaluate the intrinsic quality of SJZTC.
基金Supported by the Doctor Research Fund of Henan University of Technology,China(No.2009BS027)
文摘A rapid and effective method, solid phase extraction coupled with high performance liquid chromatography（SPE-HPLC）, was applied to the separation and analysis of ginsenosides. Waters OASIS HLB was used for concentrating and purifying samples and Alltima C18（53 mm×7 mm, 3 μm） chromatography column was used for separating ginsenoside Rg1, Re, Rb1, Rc, Rb2 and Rd. These ginsenosides were analyzed within 20 min in our gradient elution process and the equilibrium time of the chromatography column cost only 5 min. Moreover, there was no obvious baseline drift in our experiment. This method was used to analyze the contents of ginsenosides in different ginseng products for quality control. Four ginseng products were studied, including two kinds of capsules, one kind of tablet and one kind of injection. The results show that the method developed in this paper had good accuracy, linearity and precision. Therefore, this method could be applied in quality control of ginseng products.
文摘为提高船舶总体设计质效,本文基于船舶设计、多学科设计优化(Multi-disciplinary Design and Optimization,MDO)理论及其应用的相关资料,在梳理现阶段船舶设计理论及基本流程的基础上,分析MDO理论在指导船舶设计中应用的可行性。结果表明,在船舶设计过程中应重点关注船舶型线设计、推进系统设计及振动噪声性能控制等关键技术。通过分析上述技术方面的研究进展,并基于MDO理论提出若干关于提高船舶总体设计质效的建议,对改进船舶总体设计方法具有一定工程指导价值。
基金supported by Shineway Pharmaceutical Group Ltd.(No.2020110031006073).
文摘Objective:Huamaoyan Granules(HMYG)and Huamaoyan Capsules(HMYC)are Chinese patent medicines with different dosage forms of the same prescription.Due to the different preparation process,the chemical composition of these Chinese patent medicines varies greatly among different forms,but there were few studies on the difference comparison and quality control of them.In order to improve the effectiveness and safety in its clinical application,an idea combining high performance liquid chromatography(HPLC)and chemometrics was put forward to study the quality control of Chinese patent medicines in different dosage forms of the same prescription.Methods:The differential markers of HMYG and HMYC were explored based on HPLC fingerprint and chemometrics including orthogonal projections to latent structures-discriminant analysis(OPLS-DA),principal component analysis(PCA),and hierarchical cluster analysis(HCA).Finally,the quantitative analysis method of related components was established by HPLC.Results:A quality control method for HMYG and HMYC was established.Firstly,the chemical components of HMYG and HMYC were systematically analyzed by HPLC fingerprinting.Further exploration showed that there were 20 characteristic peaks and 57 common peaks.Then,the potential differential markers between HMYG and HMYC were explored by chemometrics,and the differential markers were screened after intersection with the 20 characteristic peaks.Finally,HPLC quantitative analysis methods for nine components were established,including seven differential markers(neochlorogenic acid,protocatechualdehyde,chlorogenic acid,cryptochlorogenic acid,caffeic acid,rosmarinic acid and salvianolic acid A).The results of HPLC quantitative analysis showed that the contents of eight components in HMYG and HMYC samples were significantly different.According to the above results,the differential markers between HMYG and HMYC screened based on HPLC fingerprint and chemometrics can effectively characterize the differences between the two dosage forms.Conclusion:The present work provides a rapid and effective method for routine quality evaluation and control of HMYG and HMYC.This work also provides feasible methods for the quality evaluation and control of Chinese patent medicines with different dosage forms of the same prescription.
