BACKGROUND Gastrointestinal neoplasm(GN)significantly impact the global cancer burden and mortality,necessitating early detection and treatment.Understanding the evolution and current state of research in this field i...BACKGROUND Gastrointestinal neoplasm(GN)significantly impact the global cancer burden and mortality,necessitating early detection and treatment.Understanding the evolution and current state of research in this field is vital.AIM To conducts a comprehensive bibliometric analysis of publications from 1984 to 2022 to elucidate the trends and hotspots in the GN risk assessment research,focusing on key contributors,institutions,and thematic evolution.METHODS This study conducted a bibliometric analysis of data from the Web of Science Core Collection database using the"bibliometrix"R package,VOSviewer,and CiteSpace.The analysis focused on the distribution of publications,contributions by institutions and countries,and trends in keywords.The methods included data synthesis,network analysis,and visualization of international collaboration networks.RESULTS This analysis of 1371 articles on GN risk assessment revealed a notable evolution in terms of research focus and collaboration.It highlights the United States'critical role in advancing this field,with significant contributions from institutions such as Brigham and Women's Hospital and the National Cancer Institute.The last five years,substantial advancements have been made,representing nearly 45%of the examined literature.Publication rates have dramatically increased,from 20 articles in 2002 to 112 in 2022,reflecting intensified research efforts.This study underscores a growing trend toward interdisciplinary and international collaboration,with the Journal of Clinical Oncology standing out as a key publication outlet.This shift toward more comprehensive and collaborative research methods marks a significant step in addressing GN risks.CONCLUSION This study underscores advancements in GN risk assessment through genetic analyses and machine learning and reveals significant geographical disparities in research emphasis.This calls for enhanced global collaboration and integration of artificial intelligence to improve cancer prevention and treatment accuracy,ultimately enhancing worldwide patient care.展开更多
According to international standard plant quarantine measures and principle risk analysis(ISPM No.11),a risk assessment was carried out for Passalora sequoiae through geographical distribution,possibility of colonizat...According to international standard plant quarantine measures and principle risk analysis(ISPM No.11),a risk assessment was carried out for Passalora sequoiae through geographical distribution,possibility of colonization,probability of diffusion,economic importance and difficulty in risk management.Results show that P.sequoiae has a greater risk of introduction and diffusion,and it has distributed in parts of China.It is suggested that P.sequoiae should be added to the list of forest dangerous pests in China.Besides,porting departments should focus on the pathogen on imported host seedlings like Cryptomeria.展开更多
The tragedy of Vila Socó epitomizes the socio-environmental repercussions of rapid industrialization in Cubatão. Beginning in the 1940s with the construction of the Anchieta highway, the city experienced an ...The tragedy of Vila Socó epitomizes the socio-environmental repercussions of rapid industrialization in Cubatão. Beginning in the 1940s with the construction of the Anchieta highway, the city experienced an influx of migrants drawn by burgeoning industries, leading to unplanned urban growth and the emergence of vulnerable communities like Vila Socó. This article examines the interconnected factors—such as demographic shifts, inadequate planning, and regulatory oversight—that culminated in the devastating fire of 1984, claiming numerous lives and highlighting systemic failures. Utilizing the Haddon Matrix, this study dissects the Vila Socó incident, emphasizing the roles of human error, infrastructure integrity, and socio-economic disparities in disaster causation. By contextualizing the tragedy within Cubatão’s industrial trajectory, it underscores the urgent need for comprehensive risk assessment and proactive mitigation strategies in rapidly developing regions globally. Beyond its immediate focus, this work offers broader insights into the dynamics of industrial disasters and their socio-economic implications. As pipelines continue to play a vital role in global energy infrastructure, the lessons drawn from Vila Socó’s tragedy resonate deeply, emphasizing the imperative of robust safety protocols and accountable governance to prevent similar catastrophes in the future.展开更多
One of the down sides of crude oil exploration and exploitation in the developing nations is its impacts on the environment. A major manifestation of poor crude oil management is oil-spillages. Mitigation strategies h...One of the down sides of crude oil exploration and exploitation in the developing nations is its impacts on the environment. A major manifestation of poor crude oil management is oil-spillages. Mitigation strategies have been too expensive, but a cheaper recent way of managing crude-spills is by developing a severity risk analysis matrix ranking (SRAMR). The spatial data-sets deployed in this study were acquired from the USGS, Google Earth Pro, and NOSDRA. A buffer zone of 100 - 400 meters was created to characterize the LULC characteristics of the area. Also, this was to help develop a risk sensitivity characteristic. The study found that the vegetal cover was the environmental resource at high risk to crude-spills in the area, while other land-uses were at low risk of crude-spill. It is hoped that the finding from this study informs policy development and planning for crude oil spill incidents.展开更多
Objective:To analyze the existing risks in breast milk management at the neonatal department and provide corresponding countermeasures.Methods:22 risk events were identified in 7 risk links in the process of bottle-fe...Objective:To analyze the existing risks in breast milk management at the neonatal department and provide corresponding countermeasures.Methods:22 risk events were identified in 7 risk links in the process of bottle-feeding of breast milk.Hazard Vulnerability Analysis based on the Kaiser model was applied to investigate and evaluate the risk events.Results:High-risk events include breast milk quality inspection,hand hygiene during collection,disinfection of collectors,cold chain management,hand hygiene during the reception,breast milk closed-loop management,and post-collection disposal.Root cause analysis of high-risk events was conducted and breast milk management strategies outside the hospital and within the neonatal department were proposed.Conclusion:Hazard Vulnerability Analysis based on the Kaiser model can identify and assess neonatal breast milk management risks effectively,which helps improve the management of neonatal breast milk.It is conducive to the safe development and promotion of bottle feeding of breast milk for neonates,ensuring the quality of medical services and the safety of children.展开更多
This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends t...This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends that they are not the same. The concept of cyber security is explored, which goes beyond protecting information resources to include a wider variety of assets, including people [1]. Protecting information assets is the main goal of traditional information security, with consideration to the human element and how people fit into the security process. On the other hand, cyber security adds a new level of complexity, as people might unintentionally contribute to or become targets of cyberattacks. This aspect presents moral questions since it is becoming more widely accepted that society has a duty to protect weaker members of society, including children [1]. The study emphasizes how important cyber security is on a larger scale, with many countries creating plans and laws to counteract cyberattacks. Nevertheless, a lot of these sources frequently neglect to define the differences or the relationship between information security and cyber security [1]. The paper focus on differentiating between cybersecurity and information security on a larger scale. The study also highlights other areas of cybersecurity which includes defending people, social norms, and vital infrastructure from threats that arise from online in addition to information and technology protection. It contends that ethical issues and the human factor are becoming more and more important in protecting assets in the digital age, and that cyber security is a paradigm shift in this regard [1].展开更多
In this study, 30 sediment samples were collected from the lower reaches of the Shichuanhe River in Xi’an, Shaanxi Province, China, to test the distribution of heavy metal elements in this area and for an analysis of...In this study, 30 sediment samples were collected from the lower reaches of the Shichuanhe River in Xi’an, Shaanxi Province, China, to test the distribution of heavy metal elements in this area and for an analysis of the pollution levels of this area, hope to provide guidance on agricultural production activities in this region. The results show that the heavy metal elements in this area are mainly concentrated at the Qinghe River and Shichuanhe River confluences. Furthermore, the element contents are higher than that of the background levels of the continental crust(UCC) and close to the background levels of the soil from Shaanxi Province;the two most enriched elements are Cd and As, with contents of 0.79 and 22.7 mg·kg-1, respectively, and their contents are 3.8 and 1.72 times higher than that of the background values. Herein, the heavy metal pollution assessment methods applied indicated that Cd and As are the two most abundant pollutant elements in the area’s soils. As has a peak geo-accumulation index value of 3, and the pollution level is high, while Cd exhibits high potential ecological risks due to its high toxicity(potential risk index of 143) and an active fraction of more than 64%.In addition, a principal component analysis and hierarchical cluster analysis study showed that there are two sources of the heavy metals in this area. The Zn, As, Ni, Cu, Pb,and Cr are mainly from natural sources, and the Cd likely comes from a discharge of untreated agricultural wastewater in the region. The Cd which poses a high potential risk and mainly results from human activities, needs to be further monitored.展开更多
This paper proposes a risk analysis framework for substation structures based on reliability methods.Even though several risk assessment approaches have been developed for buildings,detailed risk analysis procedures f...This paper proposes a risk analysis framework for substation structures based on reliability methods.Even though several risk assessment approaches have been developed for buildings,detailed risk analysis procedures for infrastructure components have been lacking in prior studies.The proposed framework is showcased by its application to a system of interconnected structures at a power substation in Tehran.Finite element models of structures are developed and validated in accordance with previous experiments.The uncertainties in the material,mass,and geometric properties of structures are described by random variables that are input to the finite element model.An artificial ground motion model is employed to comprehensively consider uncertainty in ground motion.Monte Carlo sampling is subsequently conducted on the library of probabilistic models.The analysis resulted in the loss distribution in the life cycle of structures.Additionally,the loss associated with six earthquake scenarios having specific magnitudes and return periods is computed.The application provides insight into the most vulnerable equipment in the considered system.Furthermore,introduced risk measures can guide stakeholders to make risk-based decisions to optimize design or prioritize a retrofit of infrastructure components under conditions of uncertainty.展开更多
BACKGROUND Some studies have directed towards an association between diabetes mellitus(DM)and prostate cancer(PCa);however,this specific relationship remains inconclusive.In recent years,Mendelian randomization(MR)has...BACKGROUND Some studies have directed towards an association between diabetes mellitus(DM)and prostate cancer(PCa);however,this specific relationship remains inconclusive.In recent years,Mendelian randomization(MR)has become a widely used analytical method for inferring epidemiological causes.AIM To investigated the potential relationship between DM and PCa using MR.METHODS We downloaded relevant data on"diabetes"and"PCa"from the IEU OpenGWAS project database,performed three different methods to conduct MR,and carried out sensitivity analysis for verification.RESULTS The results indicated that DM was an independent risk factor for PCa.The odds ratio(OR)values obtained using the inverse variance weighted method in this study were as follows:OR=1.018(95%confidence interval:1.004-1.032),P=0.014.CONCLUSION We found that DM could increase the incidence rate of PCa.展开更多
Background:Breast cancer and endometriosis are two significant diseases that threaten the health of female worldwide.The relationship between them is still in a state of controversy.In present study,we identified the ...Background:Breast cancer and endometriosis are two significant diseases that threaten the health of female worldwide.The relationship between them is still in a state of controversy.In present study,we identified the risk of breast cancer in patients with endometriosis through a meta-analysis.Methods:A systematic search of the PubMed,Embase and Cochrane Library,with the terms for endometriosis,breast and cancer,tumor,neoplasm,or carcinoma combined.Studies on related risk estimates of endometriosis and breast cancer were included in the meta-analysis.Furthermore,a series of analytical methods such as sensitivity analysis,the Cochran Q test,Begg’s and Egger’s test were used to analyze the information of collected studies.Results:Finally,a total of 8 studies were included.After statistical analysis based on STATA software,the combined odds ratio of the results was 1.13(95%CI:1.09–1.17).And the results of subgroup analysis showed that the odds ratio values of different outcome indexes were 1.06(95%CI:1.02–1.09,P<0.05),the effective effect estimates were presented in SIR(P=0.006,I^(2)=80.3%).Conclusion:In present study,we identified that patients with endometriosis have an increased risk of breast cancer.It is worth considering that our research was a summary analysis of epidemiological data.More in-depth studies are needed to determine the pathophysiology of this relationship.展开更多
According to the developing of international trade,people began to pay more attention on foreign currency and its exchange.Currency risk is coming into being with changes in foreign exchange value,which affect the ret...According to the developing of international trade,people began to pay more attention on foreign currency and its exchange.Currency risk is coming into being with changes in foreign exchange value,which affect the return on loan or investments by other currencies.So,at this time,people will think about how to control the currency risk,that is risk analysis.In my opinion,risk analysis is the actions of man-展开更多
A logic fault tree of mine spontaneous combustion of sulphide ores was built by the fault tree analysis (FTA) based on a lot of mechanism investigation of sulphide ore spontaneous combustion in more than ten mines an...A logic fault tree of mine spontaneous combustion of sulphide ores was built by the fault tree analysis (FTA) based on a lot of mechanism investigation of sulphide ore spontaneous combustion in more than ten mines and review of a great amount of relevant展开更多
The socio-economic attribute of geo-hazard made us distinguish it from the traditional engineering geology study. It will get more social benefit from the analysis of the geo-hazard in the socio-economic attribute. Th...The socio-economic attribute of geo-hazard made us distinguish it from the traditional engineering geology study. It will get more social benefit from the analysis of the geo-hazard in the socio-economic attribute. The hazard and the vulnerability of the element controls the risk level of the regional geo-hazard. The risk analysis supported by GIS in geo-hazard study is one of the most important directions. Based on the author’s studies in recent years, a risk analysis system of regional geo-hazard (RiskAnly) has been developed on the basis of software MAPGIS. The paper introduces the train of system design, the structure and the workflow of RiskAnly. As a case study, the paper also deals with the risk zonation of the regional landslide hazard of China.展开更多
Background: Endoscopic retrograde cholangiopancreatography(ERCP) may have complications. Our study aimed to investigate the risk factors and prevention of post-ERCP cholangitis.Methods: We retrospectively analyzed 423...Background: Endoscopic retrograde cholangiopancreatography(ERCP) may have complications. Our study aimed to investigate the risk factors and prevention of post-ERCP cholangitis.Methods: We retrospectively analyzed 4234 cases undergone ERCP in the Affiliated Drum Tower Hospital of Nanjing University Medical School from January 2008 to December 2013. Patient-related factors and procedure-related factors were analyzed to find the risk factors of post-ERCP cholangitis. The time point of post-ERCP cholangitis was also analyzed. Univariate and multivariate analyses were performed to define the independent risk factors of post-ERCP cholangitis.Results: The success rate of ERCP was 96.8%(4099/4234). The overall complication rate was 9.4%(399/4234). Post-ERCP cholangitis occurred in 102 cases(2.4%, 102/4234). The most dangerous time of post-ERCP cholangitis was from 24 h–48 h after ERCP(45.1%, 46/102). Univariate analysis revealed that age, hypertension, diabetes, previous ERCP history, biliary stent insertion, pancreatography, endoscopic sphincterotomy, balloon dilation and hilar obstruction were risk factors of post-ERCP cholangitis(P < 0.05). Multivariate analysis indicated that age, previous ERCP history and hilar obstruction were independent risk factors(P < 0.05). While endoscopic stone extraction was the potential protective factor.Conclusions: Many risk factors are involved in post-ERCP cholangitis. Among them, old age, previous ERCP history and hilar obstruction were independently related to this post-ERCP complication.展开更多
Drilling engineering has great uncertainty and it always involves huge investment and high risk. Risk analysis of extended reach drilling (ERD) is very important to prevent complex failures and to improve drilling e...Drilling engineering has great uncertainty and it always involves huge investment and high risk. Risk analysis of extended reach drilling (ERD) is very important to prevent complex failures and to improve drilling efficiency. Nowadays there are few reports on how to analyze quantitatively the drilling risk for extended reach wells (ERWs). Based on the fuzzy set theory, a comprehensive fuzzy evaluation model for analyzing risks of ERD is proposed in this paper. Well B6ERW07 is a planned 8,000-meter ERW with a high ratio of horizontal displacement (HD) to vertical depth (VD) in the Liuhua Oilfield, the South China Sea, China. On the basis of the evaluation model developed in this study, the risk for drilling Well B6ERW07 was evaluated before drilling. The evaluation result shows that the success rate of drilling this well is predicted to be 51.9%, providing important rational and scientific information for the decisionmakers.展开更多
The present risk analysis model of engineering investment is built by fuzzy hierarchy approach under the assumption of maximizing the revenues of the project during its whole life cycle of operation. It can reasonably...The present risk analysis model of engineering investment is built by fuzzy hierarchy approach under the assumption of maximizing the revenues of the project during its whole life cycle of operation. It can reasonably be expressed by a system evaluation analysis. As a matter of fact, the system, aimed by its system goal can be modelled by a set of factors, constitutively structured by certain links between them, to form a factorial network chart, which represents the essentials of the system behaviours, the nodes of which represent the factors concerned. The weight distribution between factors located at the same level can be determined by the eigen-value problem of a 'pair comparison' relation matrix. The weight distribution of factors at each level is successively manipulated until the fuzzy synthetic risk assessment. As an example of risk analysis of engineering investment, a harbour construction project is presented for illustration.展开更多
This article presents the application of an integrated method that estimates the dispersion of polycyclic aromatic hydrocarbons (PAHs) in air, and assesses the human health risk associated with PAHs inhalation. An u...This article presents the application of an integrated method that estimates the dispersion of polycyclic aromatic hydrocarbons (PAHs) in air, and assesses the human health risk associated with PAHs inhalation. An uncertainty analysis method consisting of three components were applied in this study, where the three components include a bootstrapping method for analyzing the whole process associated uncertainty, an inhalation rate (IR) representation for evaluating the total PAH inhalation risk for human health, and a normally distributed absorption fraction (AF) ranging from 0% to 100% to represent the absorption capability of PAHs in human body. Using this method, an integrated process was employed to assess the health risk of the residents in Beijing, China, from inhaling PAHs in the air. The results indicate that the ambient air PAHs in Beijing is an important contributor to human health impairment, although over 68% of residents seem to be safe from daily PAH carcinogenic inhalation. In general, the accumulated daily inhalation amount is relatively higher for male and children at 10 years old of age than for female and children at 6 years old. In 1997, about 1.73% cancer sufferers in Beijing were more or less related to ambient air PAHs inhalation. At 95% confidence interval, approximately 272-309 individual cancer incidences can be attributed to PAHs pollution in the air. The probability of greater than 500 cancer occurrence is 15.3%. While the inhalation of ambient air PAHs was shown to be an important factor responsible for higher cancer occurrence in Beijing, while the contribution might not be the most significant one.展开更多
Risk analysis and assessment relating coastal structures has been one of the hot topics in the area of coastal protection recently. In this paper, from three aspects of joint return period of multiple loads, dike fail...Risk analysis and assessment relating coastal structures has been one of the hot topics in the area of coastal protection recently. In this paper, from three aspects of joint return period of multiple loads, dike failure rate and dike continuous risk prevention respectively, three new risk analysis methods concerning overtopping of sea dikes are developed. It is worth noting that the factors of storm surge which leads to overtopping are also considered in the three methods. In order to verify and estimate the effectiveness and reliability of the newly developed methods, quantified mutual information is adopted. By means of case testing, it can be found that different prior variables might be selected dividedly, according to the requirement of special engineering application or the dominance of loads. Based on the selection of prior variables, the correlating risk analysis method can be successfully applied to practical engineering.展开更多
基金Supported by National Natural Science Foundation of China,No.72104183Shanghai Municipal Health Commission Project,No.20234Y0057+4 种基金Shanghai Sailing Program,No.20YF1444900Shanghai Hospital Association Project,No.X2022142Projects of the Committee of Shanghai Science and Technology,No.20Y11913700Guangdong Association of Clinical Trials(GACT)/Chinese Thoracic Oncology Group(CTONG)and Guangdong Provincial Key Lab of Translational Medicine in Lung Cancer,No.2017B030314120Beijing CSCO(Sisco)Clinical Oncology Research Grant,No.Y-HS202101-0205.
文摘BACKGROUND Gastrointestinal neoplasm(GN)significantly impact the global cancer burden and mortality,necessitating early detection and treatment.Understanding the evolution and current state of research in this field is vital.AIM To conducts a comprehensive bibliometric analysis of publications from 1984 to 2022 to elucidate the trends and hotspots in the GN risk assessment research,focusing on key contributors,institutions,and thematic evolution.METHODS This study conducted a bibliometric analysis of data from the Web of Science Core Collection database using the"bibliometrix"R package,VOSviewer,and CiteSpace.The analysis focused on the distribution of publications,contributions by institutions and countries,and trends in keywords.The methods included data synthesis,network analysis,and visualization of international collaboration networks.RESULTS This analysis of 1371 articles on GN risk assessment revealed a notable evolution in terms of research focus and collaboration.It highlights the United States'critical role in advancing this field,with significant contributions from institutions such as Brigham and Women's Hospital and the National Cancer Institute.The last five years,substantial advancements have been made,representing nearly 45%of the examined literature.Publication rates have dramatically increased,from 20 articles in 2002 to 112 in 2022,reflecting intensified research efforts.This study underscores a growing trend toward interdisciplinary and international collaboration,with the Journal of Clinical Oncology standing out as a key publication outlet.This shift toward more comprehensive and collaborative research methods marks a significant step in addressing GN risks.CONCLUSION This study underscores advancements in GN risk assessment through genetic analyses and machine learning and reveals significant geographical disparities in research emphasis.This calls for enhanced global collaboration and integration of artificial intelligence to improve cancer prevention and treatment accuracy,ultimately enhancing worldwide patient care.
基金Supported by Projects of General Administration of Customs(2020HK159)Nanjing Customs Research Projects(2023KJ20).
文摘According to international standard plant quarantine measures and principle risk analysis(ISPM No.11),a risk assessment was carried out for Passalora sequoiae through geographical distribution,possibility of colonization,probability of diffusion,economic importance and difficulty in risk management.Results show that P.sequoiae has a greater risk of introduction and diffusion,and it has distributed in parts of China.It is suggested that P.sequoiae should be added to the list of forest dangerous pests in China.Besides,porting departments should focus on the pathogen on imported host seedlings like Cryptomeria.
文摘The tragedy of Vila Socó epitomizes the socio-environmental repercussions of rapid industrialization in Cubatão. Beginning in the 1940s with the construction of the Anchieta highway, the city experienced an influx of migrants drawn by burgeoning industries, leading to unplanned urban growth and the emergence of vulnerable communities like Vila Socó. This article examines the interconnected factors—such as demographic shifts, inadequate planning, and regulatory oversight—that culminated in the devastating fire of 1984, claiming numerous lives and highlighting systemic failures. Utilizing the Haddon Matrix, this study dissects the Vila Socó incident, emphasizing the roles of human error, infrastructure integrity, and socio-economic disparities in disaster causation. By contextualizing the tragedy within Cubatão’s industrial trajectory, it underscores the urgent need for comprehensive risk assessment and proactive mitigation strategies in rapidly developing regions globally. Beyond its immediate focus, this work offers broader insights into the dynamics of industrial disasters and their socio-economic implications. As pipelines continue to play a vital role in global energy infrastructure, the lessons drawn from Vila Socó’s tragedy resonate deeply, emphasizing the imperative of robust safety protocols and accountable governance to prevent similar catastrophes in the future.
文摘One of the down sides of crude oil exploration and exploitation in the developing nations is its impacts on the environment. A major manifestation of poor crude oil management is oil-spillages. Mitigation strategies have been too expensive, but a cheaper recent way of managing crude-spills is by developing a severity risk analysis matrix ranking (SRAMR). The spatial data-sets deployed in this study were acquired from the USGS, Google Earth Pro, and NOSDRA. A buffer zone of 100 - 400 meters was created to characterize the LULC characteristics of the area. Also, this was to help develop a risk sensitivity characteristic. The study found that the vegetal cover was the environmental resource at high risk to crude-spills in the area, while other land-uses were at low risk of crude-spill. It is hoped that the finding from this study informs policy development and planning for crude oil spill incidents.
文摘Objective:To analyze the existing risks in breast milk management at the neonatal department and provide corresponding countermeasures.Methods:22 risk events were identified in 7 risk links in the process of bottle-feeding of breast milk.Hazard Vulnerability Analysis based on the Kaiser model was applied to investigate and evaluate the risk events.Results:High-risk events include breast milk quality inspection,hand hygiene during collection,disinfection of collectors,cold chain management,hand hygiene during the reception,breast milk closed-loop management,and post-collection disposal.Root cause analysis of high-risk events was conducted and breast milk management strategies outside the hospital and within the neonatal department were proposed.Conclusion:Hazard Vulnerability Analysis based on the Kaiser model can identify and assess neonatal breast milk management risks effectively,which helps improve the management of neonatal breast milk.It is conducive to the safe development and promotion of bottle feeding of breast milk for neonates,ensuring the quality of medical services and the safety of children.
文摘This paper examines how cybersecurity is developing and how it relates to more conventional information security. Although information security and cyber security are sometimes used synonymously, this study contends that they are not the same. The concept of cyber security is explored, which goes beyond protecting information resources to include a wider variety of assets, including people [1]. Protecting information assets is the main goal of traditional information security, with consideration to the human element and how people fit into the security process. On the other hand, cyber security adds a new level of complexity, as people might unintentionally contribute to or become targets of cyberattacks. This aspect presents moral questions since it is becoming more widely accepted that society has a duty to protect weaker members of society, including children [1]. The study emphasizes how important cyber security is on a larger scale, with many countries creating plans and laws to counteract cyberattacks. Nevertheless, a lot of these sources frequently neglect to define the differences or the relationship between information security and cyber security [1]. The paper focus on differentiating between cybersecurity and information security on a larger scale. The study also highlights other areas of cybersecurity which includes defending people, social norms, and vital infrastructure from threats that arise from online in addition to information and technology protection. It contends that ethical issues and the human factor are becoming more and more important in protecting assets in the digital age, and that cyber security is a paradigm shift in this regard [1].
基金financially supported by the Key Project of Shaanxi Provincial Natural Science Basic Research Program(2023-JC-ZD-16).
文摘In this study, 30 sediment samples were collected from the lower reaches of the Shichuanhe River in Xi’an, Shaanxi Province, China, to test the distribution of heavy metal elements in this area and for an analysis of the pollution levels of this area, hope to provide guidance on agricultural production activities in this region. The results show that the heavy metal elements in this area are mainly concentrated at the Qinghe River and Shichuanhe River confluences. Furthermore, the element contents are higher than that of the background levels of the continental crust(UCC) and close to the background levels of the soil from Shaanxi Province;the two most enriched elements are Cd and As, with contents of 0.79 and 22.7 mg·kg-1, respectively, and their contents are 3.8 and 1.72 times higher than that of the background values. Herein, the heavy metal pollution assessment methods applied indicated that Cd and As are the two most abundant pollutant elements in the area’s soils. As has a peak geo-accumulation index value of 3, and the pollution level is high, while Cd exhibits high potential ecological risks due to its high toxicity(potential risk index of 143) and an active fraction of more than 64%.In addition, a principal component analysis and hierarchical cluster analysis study showed that there are two sources of the heavy metals in this area. The Zn, As, Ni, Cu, Pb,and Cr are mainly from natural sources, and the Cd likely comes from a discharge of untreated agricultural wastewater in the region. The Cd which poses a high potential risk and mainly results from human activities, needs to be further monitored.
文摘This paper proposes a risk analysis framework for substation structures based on reliability methods.Even though several risk assessment approaches have been developed for buildings,detailed risk analysis procedures for infrastructure components have been lacking in prior studies.The proposed framework is showcased by its application to a system of interconnected structures at a power substation in Tehran.Finite element models of structures are developed and validated in accordance with previous experiments.The uncertainties in the material,mass,and geometric properties of structures are described by random variables that are input to the finite element model.An artificial ground motion model is employed to comprehensively consider uncertainty in ground motion.Monte Carlo sampling is subsequently conducted on the library of probabilistic models.The analysis resulted in the loss distribution in the life cycle of structures.Additionally,the loss associated with six earthquake scenarios having specific magnitudes and return periods is computed.The application provides insight into the most vulnerable equipment in the considered system.Furthermore,introduced risk measures can guide stakeholders to make risk-based decisions to optimize design or prioritize a retrofit of infrastructure components under conditions of uncertainty.
文摘BACKGROUND Some studies have directed towards an association between diabetes mellitus(DM)and prostate cancer(PCa);however,this specific relationship remains inconclusive.In recent years,Mendelian randomization(MR)has become a widely used analytical method for inferring epidemiological causes.AIM To investigated the potential relationship between DM and PCa using MR.METHODS We downloaded relevant data on"diabetes"and"PCa"from the IEU OpenGWAS project database,performed three different methods to conduct MR,and carried out sensitivity analysis for verification.RESULTS The results indicated that DM was an independent risk factor for PCa.The odds ratio(OR)values obtained using the inverse variance weighted method in this study were as follows:OR=1.018(95%confidence interval:1.004-1.032),P=0.014.CONCLUSION We found that DM could increase the incidence rate of PCa.
文摘Background:Breast cancer and endometriosis are two significant diseases that threaten the health of female worldwide.The relationship between them is still in a state of controversy.In present study,we identified the risk of breast cancer in patients with endometriosis through a meta-analysis.Methods:A systematic search of the PubMed,Embase and Cochrane Library,with the terms for endometriosis,breast and cancer,tumor,neoplasm,or carcinoma combined.Studies on related risk estimates of endometriosis and breast cancer were included in the meta-analysis.Furthermore,a series of analytical methods such as sensitivity analysis,the Cochran Q test,Begg’s and Egger’s test were used to analyze the information of collected studies.Results:Finally,a total of 8 studies were included.After statistical analysis based on STATA software,the combined odds ratio of the results was 1.13(95%CI:1.09–1.17).And the results of subgroup analysis showed that the odds ratio values of different outcome indexes were 1.06(95%CI:1.02–1.09,P<0.05),the effective effect estimates were presented in SIR(P=0.006,I^(2)=80.3%).Conclusion:In present study,we identified that patients with endometriosis have an increased risk of breast cancer.It is worth considering that our research was a summary analysis of epidemiological data.More in-depth studies are needed to determine the pathophysiology of this relationship.
文摘According to the developing of international trade,people began to pay more attention on foreign currency and its exchange.Currency risk is coming into being with changes in foreign exchange value,which affect the return on loan or investments by other currencies.So,at this time,people will think about how to control the currency risk,that is risk analysis.In my opinion,risk analysis is the actions of man-
文摘A logic fault tree of mine spontaneous combustion of sulphide ores was built by the fault tree analysis (FTA) based on a lot of mechanism investigation of sulphide ore spontaneous combustion in more than ten mines and review of a great amount of relevant
基金National Natural Science Foundation of China, No. 40072084
文摘The socio-economic attribute of geo-hazard made us distinguish it from the traditional engineering geology study. It will get more social benefit from the analysis of the geo-hazard in the socio-economic attribute. The hazard and the vulnerability of the element controls the risk level of the regional geo-hazard. The risk analysis supported by GIS in geo-hazard study is one of the most important directions. Based on the author’s studies in recent years, a risk analysis system of regional geo-hazard (RiskAnly) has been developed on the basis of software MAPGIS. The paper introduces the train of system design, the structure and the workflow of RiskAnly. As a case study, the paper also deals with the risk zonation of the regional landslide hazard of China.
基金supported by grants from the outstanding Youth Project of Nanjing Medical Scientific and Technological Development Project of Nanjing City(JQX14005)
文摘Background: Endoscopic retrograde cholangiopancreatography(ERCP) may have complications. Our study aimed to investigate the risk factors and prevention of post-ERCP cholangitis.Methods: We retrospectively analyzed 4234 cases undergone ERCP in the Affiliated Drum Tower Hospital of Nanjing University Medical School from January 2008 to December 2013. Patient-related factors and procedure-related factors were analyzed to find the risk factors of post-ERCP cholangitis. The time point of post-ERCP cholangitis was also analyzed. Univariate and multivariate analyses were performed to define the independent risk factors of post-ERCP cholangitis.Results: The success rate of ERCP was 96.8%(4099/4234). The overall complication rate was 9.4%(399/4234). Post-ERCP cholangitis occurred in 102 cases(2.4%, 102/4234). The most dangerous time of post-ERCP cholangitis was from 24 h–48 h after ERCP(45.1%, 46/102). Univariate analysis revealed that age, hypertension, diabetes, previous ERCP history, biliary stent insertion, pancreatography, endoscopic sphincterotomy, balloon dilation and hilar obstruction were risk factors of post-ERCP cholangitis(P < 0.05). Multivariate analysis indicated that age, previous ERCP history and hilar obstruction were independent risk factors(P < 0.05). While endoscopic stone extraction was the potential protective factor.Conclusions: Many risk factors are involved in post-ERCP cholangitis. Among them, old age, previous ERCP history and hilar obstruction were independently related to this post-ERCP complication.
基金supported by the National Natural Science Foundation of China (Grant No 50609005)the Science Foundation of Guangxi Education Department (Grant No 200708LX099)the Science Foundation of Guangxi University (Grant No X071096)
基金support from the project of CNOOC China Limited-Shenzhen (Grant No. Z2007SLSZ-034)the foundation project of the State Key Laboratory of Petroleum Resource and Prospecting (Grant No. PRPDX2008-08) is gratefully acknowledged
文摘Drilling engineering has great uncertainty and it always involves huge investment and high risk. Risk analysis of extended reach drilling (ERD) is very important to prevent complex failures and to improve drilling efficiency. Nowadays there are few reports on how to analyze quantitatively the drilling risk for extended reach wells (ERWs). Based on the fuzzy set theory, a comprehensive fuzzy evaluation model for analyzing risks of ERD is proposed in this paper. Well B6ERW07 is a planned 8,000-meter ERW with a high ratio of horizontal displacement (HD) to vertical depth (VD) in the Liuhua Oilfield, the South China Sea, China. On the basis of the evaluation model developed in this study, the risk for drilling Well B6ERW07 was evaluated before drilling. The evaluation result shows that the success rate of drilling this well is predicted to be 51.9%, providing important rational and scientific information for the decisionmakers.
文摘The present risk analysis model of engineering investment is built by fuzzy hierarchy approach under the assumption of maximizing the revenues of the project during its whole life cycle of operation. It can reasonably be expressed by a system evaluation analysis. As a matter of fact, the system, aimed by its system goal can be modelled by a set of factors, constitutively structured by certain links between them, to form a factorial network chart, which represents the essentials of the system behaviours, the nodes of which represent the factors concerned. The weight distribution between factors located at the same level can be determined by the eigen-value problem of a 'pair comparison' relation matrix. The weight distribution of factors at each level is successively manipulated until the fuzzy synthetic risk assessment. As an example of risk analysis of engineering investment, a harbour construction project is presented for illustration.
文摘This article presents the application of an integrated method that estimates the dispersion of polycyclic aromatic hydrocarbons (PAHs) in air, and assesses the human health risk associated with PAHs inhalation. An uncertainty analysis method consisting of three components were applied in this study, where the three components include a bootstrapping method for analyzing the whole process associated uncertainty, an inhalation rate (IR) representation for evaluating the total PAH inhalation risk for human health, and a normally distributed absorption fraction (AF) ranging from 0% to 100% to represent the absorption capability of PAHs in human body. Using this method, an integrated process was employed to assess the health risk of the residents in Beijing, China, from inhaling PAHs in the air. The results indicate that the ambient air PAHs in Beijing is an important contributor to human health impairment, although over 68% of residents seem to be safe from daily PAH carcinogenic inhalation. In general, the accumulated daily inhalation amount is relatively higher for male and children at 10 years old of age than for female and children at 6 years old. In 1997, about 1.73% cancer sufferers in Beijing were more or less related to ambient air PAHs inhalation. At 95% confidence interval, approximately 272-309 individual cancer incidences can be attributed to PAHs pollution in the air. The probability of greater than 500 cancer occurrence is 15.3%. While the inhalation of ambient air PAHs was shown to be an important factor responsible for higher cancer occurrence in Beijing, while the contribution might not be the most significant one.
基金supported by Fundamental Research Funds for the Central Universities(Grant No.201362030)National Natural Science Foundation of China(Grant Nos.41106077 and 51379195)+3 种基金Zhejiang Provincial Natural Science Foundation(Grant No.R5110036)Shandong Provincial Natural Science Foundation(Grant No.ZR2013EEM034)Open Fund of the Key Laboratory of Research on Marine Hazards Forecasting(Grant No.LOMF1101)SRF for ROCS,SEM
文摘Risk analysis and assessment relating coastal structures has been one of the hot topics in the area of coastal protection recently. In this paper, from three aspects of joint return period of multiple loads, dike failure rate and dike continuous risk prevention respectively, three new risk analysis methods concerning overtopping of sea dikes are developed. It is worth noting that the factors of storm surge which leads to overtopping are also considered in the three methods. In order to verify and estimate the effectiveness and reliability of the newly developed methods, quantified mutual information is adopted. By means of case testing, it can be found that different prior variables might be selected dividedly, according to the requirement of special engineering application or the dominance of loads. Based on the selection of prior variables, the correlating risk analysis method can be successfully applied to practical engineering.