目的:探究血乳酸、红细胞体积分布宽度(Red blood cell volume distribution width,RDW)、血小板体积分布宽度(Platelet volume distribution width,PDW)与急性上消化道出血患者病情及预后的关系。方法:回顾性分析2021年1月至2023年12...目的:探究血乳酸、红细胞体积分布宽度(Red blood cell volume distribution width,RDW)、血小板体积分布宽度(Platelet volume distribution width,PDW)与急性上消化道出血患者病情及预后的关系。方法:回顾性分析2021年1月至2023年12月期间在我院就诊的66例急性上消化道出血患者的临床资料,根据其入院时病情严重情况分为严重组(失血量≥750 mL,n=41)和非严重组(失血量<750 mL,n=25)。比较入院时两组患者血乳酸、RDW、PDW等指标水平,采用受试者工作特征(Receiver operating characteristic,ROC)曲线分析入院时血乳酸、RDW、PDW对急性上消化道出血患者的诊断效能。入院后30 d,根据快速序贯器官功能衰竭评估(Quick sequential organ failure assessment,qSOFA)评分将患者分为预后不良组(qSOFA≥1分)和预后良好组(qSOFA<1分)两亚组,比较两亚组患者入院后30 d血乳酸、RDW、PDW水平和qSOFA评分的关系。结果:入院时,严重组的血乳酸、RDW、PDW水平显著高于非严重组(P<0.05),血乳酸、RDW、PDW水平三者单一指标检测的ROC曲线下面积(Area under the ROC curve,AUC)值分别是0.861、0.769、0.763,差异具有统计学意义(P<0.05)。预后不良组入院时的血乳酸、RDW、PDW水平显著高于预后良好组(P<0.05),Pearson相关系数分析显示,血乳酸、RDW、PDW水平和qSOFA评分具有相关性。结论:血乳酸、RDW、PDW与急性上消化道出血患者预后密切相关,可以提供重要的诊断和治疗参考,帮助改善患者的预后和治疗效果。展开更多
Objective:To observe and explore the value of the combined application of red blood cell distribution width(RDW),platelet distribution width(PDW),and immunoglobulin E(IgE)in the process of clinical diagnosis of childr...Objective:To observe and explore the value of the combined application of red blood cell distribution width(RDW),platelet distribution width(PDW),and immunoglobulin E(IgE)in the process of clinical diagnosis of children with asthma.Methods:Fifty-five children with suspected asthma were admitted to the hospital from July 2021 to July 2023.They underwent a bronchodilator test upon admission and their RDW,PDW,and IgE were detected.The efficacy of diagnosis with a single indicator(RDW/PDW/IgE)and combined parameters(PDW+PDW+IgE)were compared with the results of the bronchodilator test.Results:49 cases of pediatric asthma were diagnosed by the bronchodilator test.RDW and PDW of asthmatic children were lower than those of non-asthmatic children,while the IgE of asthmatic children was higher than that of non-asthmatic children,and there was a significant difference in the RDW,PDW,and IgE among children with different degrees of asthma severity(P<0.05).The positive rate of the three combined diagnostic tests of RDW,PDW,and IgE was significantly higher than the positive rate of a single-parameter diagnosis(P<0.05).Conclusion:The combination of RDW,PDW,and IgE plays a crucial role in the clinical diagnosis of asthmatic children.These tests further improve the efficiency of clinical diagnosis and help identify the severity of the disease.展开更多
Objective:To investigate the diagnostic value of the monocyte-to-large-platelet ratio(MLPR),neutrophil-to-lymphocyte ratio(NLR),and red blood cell distribution width(RDW)for pulmonary embolism(PE)in patients with acut...Objective:To investigate the diagnostic value of the monocyte-to-large-platelet ratio(MLPR),neutrophil-to-lymphocyte ratio(NLR),and red blood cell distribution width(RDW)for pulmonary embolism(PE)in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 60 elderly AECOPD patients were enrolled and divided into embolus group(12 cases)and thrombus group(48 cases)according to whether they were combined with pulmonary embolism and the MLPR,NLR,and RDW values of the two groups were determined respectively.Results:The patients in the two groups had different degrees of vascular structural and functional abnormalities,and the MLPR,NLR,and RDW in the embolus group were significantly higher than those in the thrombus group(P<0.05);while the differences in NLR and RDW between the two groups were not significant.Conclusion:MLPR,NLR,and RDW can provide an objective basis for assessing PE in elderly AECOPD patients.展开更多
目的 本研究旨在分析瘢痕子宫再次妊娠时血栓弹力图(thromboelasmography,TEG)及红细胞分布宽度变异系数(red blood cell distribution width coefficient of variation,RDW-CV)、中性粒细胞/淋巴细胞比值(neutrophil to lymphocyte rat...目的 本研究旨在分析瘢痕子宫再次妊娠时血栓弹力图(thromboelasmography,TEG)及红细胞分布宽度变异系数(red blood cell distribution width coefficient of variation,RDW-CV)、中性粒细胞/淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)、单核细胞/淋巴细胞比值(monocyte lymphocyte ratio,MLR)以及全身免疫炎症指数(systemic immune-inflammation index,SII)等指标的变化情况,探讨凝血相关指标及炎症相关指标对瘢痕子宫再次妊娠风险预测价值。方法 回顾2021年3月1日至2024年3月1日在延安市人民医院产科住院的孕妇临床资料168例。比较瘢痕子宫不同妊娠阶段TEG及RDW-CV、NLR、MLR、SII等炎症指标的变化;比较瘢痕子宫孕妇与健康孕妇TEG及RDW-CV、NLR、MLR、SII等炎症指标的变化情况。结果 瘢痕子宫孕妇中,与中孕组相比,晚孕组孕妇TEG中的R值增加,Angle角、MA值减少(均P<0.05);NLR、MLR增高(P<0.05)。瘢痕子宫孕妇与健康孕妇相比,瘢痕子宫TEG中的R值、K值、Angle角、MA值的差异无统计学意义(均P>0.05);NLR、MLR差异有统计学意义(P<0.05)。结论 瘢痕子宫再次妊娠对TEG及部分炎症指标有影响,随着孕周数增加TEG指标与炎症指标有所变化;TEG及炎症指标联合检测可对瘢痕子宫再次妊娠风险作出预测。展开更多
目的:探讨孕早期孕妇中性粒细胞/淋巴细胞比值(NLR)、红细胞体积分布宽度(RDW)和血小板/淋巴细胞比值(PLR)水平与妊娠期糖尿病发生的相关性。方法:选取2020年5月—2021年10月于赣州市妇幼保健院进行孕检的266例妊娠8~12周的孕早期孕妇...目的:探讨孕早期孕妇中性粒细胞/淋巴细胞比值(NLR)、红细胞体积分布宽度(RDW)和血小板/淋巴细胞比值(PLR)水平与妊娠期糖尿病发生的相关性。方法:选取2020年5月—2021年10月于赣州市妇幼保健院进行孕检的266例妊娠8~12周的孕早期孕妇为研究对象,于妊娠24~28周时行75 g OGTT检查,根据检查结果将研究对象分为研究组(妊娠期糖尿病孕妇88例)和对照组(健康孕妇178例)。于妊娠8~12周孕检时经XN2000全自动血细胞分析仪检测孕早期孕妇NLR、RDW和PLR水平;于妊娠24~28周孕检时经AU5821全自动生化仪检测孕妇空腹血糖(FPG)、服糖后1 h血糖(1 h PG)、服糖后2 h血糖(2 h PG)水平;Pearson分析孕妇孕早期NLR、RDW和PLR水平与FPG、1 h PG、2 h PG水平的相关性;受试者操作特征(ROC)曲线分析孕妇孕早期NLR、RDW和PLR水平对妊娠期糖尿病的诊断效能。结果:与对照组相比,研究组孕妇NLR、RDW、PLR、FPG、1 h PG、2 h PG水平均显著高(P<0.05);孕早期孕妇NLR、RDW和PLR水平与FPG、1 h PG、2 h PG水平呈正相关(P<0.05);NLR、RDW、PLR预测妊娠期糖尿病的AUC分别为0.846、0.870、0.848,最佳截断值分别为3.64、11.60%、132.23。结论:孕早期孕妇NLR、RDW和PLR水平显著高,与FPG、1 h PG、2 h PG水平均呈正相关,并且与妊娠期糖尿病的发生密切相关,对其具有较好的预测诊断效能。展开更多
文摘目的:探究血乳酸、红细胞体积分布宽度(Red blood cell volume distribution width,RDW)、血小板体积分布宽度(Platelet volume distribution width,PDW)与急性上消化道出血患者病情及预后的关系。方法:回顾性分析2021年1月至2023年12月期间在我院就诊的66例急性上消化道出血患者的临床资料,根据其入院时病情严重情况分为严重组(失血量≥750 mL,n=41)和非严重组(失血量<750 mL,n=25)。比较入院时两组患者血乳酸、RDW、PDW等指标水平,采用受试者工作特征(Receiver operating characteristic,ROC)曲线分析入院时血乳酸、RDW、PDW对急性上消化道出血患者的诊断效能。入院后30 d,根据快速序贯器官功能衰竭评估(Quick sequential organ failure assessment,qSOFA)评分将患者分为预后不良组(qSOFA≥1分)和预后良好组(qSOFA<1分)两亚组,比较两亚组患者入院后30 d血乳酸、RDW、PDW水平和qSOFA评分的关系。结果:入院时,严重组的血乳酸、RDW、PDW水平显著高于非严重组(P<0.05),血乳酸、RDW、PDW水平三者单一指标检测的ROC曲线下面积(Area under the ROC curve,AUC)值分别是0.861、0.769、0.763,差异具有统计学意义(P<0.05)。预后不良组入院时的血乳酸、RDW、PDW水平显著高于预后良好组(P<0.05),Pearson相关系数分析显示,血乳酸、RDW、PDW水平和qSOFA评分具有相关性。结论:血乳酸、RDW、PDW与急性上消化道出血患者预后密切相关,可以提供重要的诊断和治疗参考,帮助改善患者的预后和治疗效果。
文摘Objective:To observe and explore the value of the combined application of red blood cell distribution width(RDW),platelet distribution width(PDW),and immunoglobulin E(IgE)in the process of clinical diagnosis of children with asthma.Methods:Fifty-five children with suspected asthma were admitted to the hospital from July 2021 to July 2023.They underwent a bronchodilator test upon admission and their RDW,PDW,and IgE were detected.The efficacy of diagnosis with a single indicator(RDW/PDW/IgE)and combined parameters(PDW+PDW+IgE)were compared with the results of the bronchodilator test.Results:49 cases of pediatric asthma were diagnosed by the bronchodilator test.RDW and PDW of asthmatic children were lower than those of non-asthmatic children,while the IgE of asthmatic children was higher than that of non-asthmatic children,and there was a significant difference in the RDW,PDW,and IgE among children with different degrees of asthma severity(P<0.05).The positive rate of the three combined diagnostic tests of RDW,PDW,and IgE was significantly higher than the positive rate of a single-parameter diagnosis(P<0.05).Conclusion:The combination of RDW,PDW,and IgE plays a crucial role in the clinical diagnosis of asthmatic children.These tests further improve the efficiency of clinical diagnosis and help identify the severity of the disease.
文摘Objective:To investigate the diagnostic value of the monocyte-to-large-platelet ratio(MLPR),neutrophil-to-lymphocyte ratio(NLR),and red blood cell distribution width(RDW)for pulmonary embolism(PE)in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).Methods:A total of 60 elderly AECOPD patients were enrolled and divided into embolus group(12 cases)and thrombus group(48 cases)according to whether they were combined with pulmonary embolism and the MLPR,NLR,and RDW values of the two groups were determined respectively.Results:The patients in the two groups had different degrees of vascular structural and functional abnormalities,and the MLPR,NLR,and RDW in the embolus group were significantly higher than those in the thrombus group(P<0.05);while the differences in NLR and RDW between the two groups were not significant.Conclusion:MLPR,NLR,and RDW can provide an objective basis for assessing PE in elderly AECOPD patients.
文摘目的:探讨孕早期孕妇中性粒细胞/淋巴细胞比值(NLR)、红细胞体积分布宽度(RDW)和血小板/淋巴细胞比值(PLR)水平与妊娠期糖尿病发生的相关性。方法:选取2020年5月—2021年10月于赣州市妇幼保健院进行孕检的266例妊娠8~12周的孕早期孕妇为研究对象,于妊娠24~28周时行75 g OGTT检查,根据检查结果将研究对象分为研究组(妊娠期糖尿病孕妇88例)和对照组(健康孕妇178例)。于妊娠8~12周孕检时经XN2000全自动血细胞分析仪检测孕早期孕妇NLR、RDW和PLR水平;于妊娠24~28周孕检时经AU5821全自动生化仪检测孕妇空腹血糖(FPG)、服糖后1 h血糖(1 h PG)、服糖后2 h血糖(2 h PG)水平;Pearson分析孕妇孕早期NLR、RDW和PLR水平与FPG、1 h PG、2 h PG水平的相关性;受试者操作特征(ROC)曲线分析孕妇孕早期NLR、RDW和PLR水平对妊娠期糖尿病的诊断效能。结果:与对照组相比,研究组孕妇NLR、RDW、PLR、FPG、1 h PG、2 h PG水平均显著高(P<0.05);孕早期孕妇NLR、RDW和PLR水平与FPG、1 h PG、2 h PG水平呈正相关(P<0.05);NLR、RDW、PLR预测妊娠期糖尿病的AUC分别为0.846、0.870、0.848,最佳截断值分别为3.64、11.60%、132.23。结论:孕早期孕妇NLR、RDW和PLR水平显著高,与FPG、1 h PG、2 h PG水平均呈正相关,并且与妊娠期糖尿病的发生密切相关,对其具有较好的预测诊断效能。
