In this paper, 2201 and 2212 phases as the corresponding precursor of forming 2212 and 2223 phases are discussed,and the constructive process of unit cell of 2201 phase is ascertained by XRD and chemical kinetics me...In this paper, 2201 and 2212 phases as the corresponding precursor of forming 2212 and 2223 phases are discussed,and the constructive process of unit cell of 2201 phase is ascertained by XRD and chemical kinetics method. Subsequently, the process of 221展开更多
The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells...The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming units (CFU-F). The aim of this study was to compare the main characteristics of MMSC and CFU-F derived from the bone marrow of 24 healthy donors. Growth and differentiation parameters, as well as relative expression levels of different genes were analyzed in MMSC and CFU-F. MMSC were cultivated for 5 passages. CFU-F concentration was determined for each bone marrow sample. The data obtained demonstrated the heterogeneity and hierarchical organization of both studied populations of stromal precursor cells-MMSC and CFU-F. These two types of stromal precursor cells turned to be different in most parameters studied. Altogether MMSC seemed to be more immature cells than CFU-F and took up the higher position in hierarchical tree of mesenchymal stem cells. The rate of differentiation and proliferative potential decreased with the donor’s age in both populations MMSC and CFU-F.展开更多
Objective:To classify 21 new isolates of Trypanosoma cruai(T.cruzi) according to the Discrete Typing Unit(DTU) which they belong to,as well as tune up a new pair of primers designed to detect the parasite in biologica...Objective:To classify 21 new isolates of Trypanosoma cruai(T.cruzi) according to the Discrete Typing Unit(DTU) which they belong to,as well as tune up a new pair of primers designed to detect the parasite in biological samples.Methods:Strains were isolated,DNA extracted,and classified by using three Polymerase Chain Reactions(PCR).Subsequently this DNA was used along with other isolates of various biological samples,for a new PCR using primers designed.Finally,the amplified fragments were sequenced.Results:It was observed the predominance of DTU i in Colombia,as well as the specificity of our primers for detection of T.cruzi,while no band was obtained when other species were used.Conclusions:This work reveals the genetic variability of 21 new isolates of T.cruzi in Colombia.Our primers confirmed their specificity for detecting the presence of T.cruzi.展开更多
在高中电化学学习里,学生的学习由宏观层面进入抽象的微观领域,考验学生的具体形象思维和抽象逻辑思维的相互转换能力。基于OBE理论(Outcome based education又称为成果导向教育、目标导向教育)的教学方法重视学生的个性化发展,能够让...在高中电化学学习里,学生的学习由宏观层面进入抽象的微观领域,考验学生的具体形象思维和抽象逻辑思维的相互转换能力。基于OBE理论(Outcome based education又称为成果导向教育、目标导向教育)的教学方法重视学生的个性化发展,能够让学生获得持久性理解知识。本文将OBE教育理念与高中电化学的大单元教学进行结合,提出了确定目标和学习成果、重视实践应用、团队合作和交流、多元化教学方法的对策。希望为教师在电化学教学时提供更为有效和科学的教学方法和策略,提高学生的学习效果。展开更多
目的探究重症监护室(intensive care unit,ICU)糖尿病酮症酸中毒患者应用胰岛素不同给药方式的作用效果。方法回顾性选取2023年4月—2024年5月上海市第六人民医院福建医院收治的88例ICU糖尿病酮症酸中毒患者的临床资料,根据不同治疗方...目的探究重症监护室(intensive care unit,ICU)糖尿病酮症酸中毒患者应用胰岛素不同给药方式的作用效果。方法回顾性选取2023年4月—2024年5月上海市第六人民医院福建医院收治的88例ICU糖尿病酮症酸中毒患者的临床资料,根据不同治疗方式分为对照组(n=44,多次静脉滴注小剂量胰岛素)、观察组(n=44,微量输液泵持续泵入胰岛素)。比较两组临床疗效、糖代谢指标、不良反应发生率。结果观察组治疗总有效率高于对照组,治疗15 d后的餐后2 h血糖、空腹血糖、糖化血红蛋白水平以及不良反应发生率均低于对照组,差异有统计学意义(P均<0.05)。结论ICU糖尿病酮症酸中毒注射胰岛素时选择微量输液泵持续泵入方式,可提高治疗有效率,增强控糖效果,降低不良反应的发生。展开更多
For high viscosity bulk-copolymerization of octamethylcyclotetrasiloxane and amino-silicone monomer, a multisyphon flow physical model was established.Based on the free volume and chemical reaction kinetic theories, a...For high viscosity bulk-copolymerization of octamethylcyclotetrasiloxane and amino-silicone monomer, a multisyphon flow physical model was established.Based on the free volume and chemical reaction kinetic theories, a new computational model was developed to simulate the multisyphon flow model. As to the new model, the united influence of reaction and diffusion was reviewed and analyzed. The new model was used to simulate bulk- copolymerization of octamethylcyclotetrasiloxane and amino-silicone monomer and agreed well with the results.展开更多
文摘In this paper, 2201 and 2212 phases as the corresponding precursor of forming 2212 and 2223 phases are discussed,and the constructive process of unit cell of 2201 phase is ascertained by XRD and chemical kinetics method. Subsequently, the process of 221
文摘The organization of the compartment of mesenchymal stem cells is still obscure. Two types of human stromal precursor cells are known. Both of them are analyzed in in vitro system: mesenchymal multipotent stromal cells (MMSC) and fibroblast colony forming units (CFU-F). The aim of this study was to compare the main characteristics of MMSC and CFU-F derived from the bone marrow of 24 healthy donors. Growth and differentiation parameters, as well as relative expression levels of different genes were analyzed in MMSC and CFU-F. MMSC were cultivated for 5 passages. CFU-F concentration was determined for each bone marrow sample. The data obtained demonstrated the heterogeneity and hierarchical organization of both studied populations of stromal precursor cells-MMSC and CFU-F. These two types of stromal precursor cells turned to be different in most parameters studied. Altogether MMSC seemed to be more immature cells than CFU-F and took up the higher position in hierarchical tree of mesenchymal stem cells. The rate of differentiation and proliferative potential decreased with the donor’s age in both populations MMSC and CFU-F.
基金funded by a FPU a grant from the Ministry of Education of Spain
文摘Objective:To classify 21 new isolates of Trypanosoma cruai(T.cruzi) according to the Discrete Typing Unit(DTU) which they belong to,as well as tune up a new pair of primers designed to detect the parasite in biological samples.Methods:Strains were isolated,DNA extracted,and classified by using three Polymerase Chain Reactions(PCR).Subsequently this DNA was used along with other isolates of various biological samples,for a new PCR using primers designed.Finally,the amplified fragments were sequenced.Results:It was observed the predominance of DTU i in Colombia,as well as the specificity of our primers for detection of T.cruzi,while no band was obtained when other species were used.Conclusions:This work reveals the genetic variability of 21 new isolates of T.cruzi in Colombia.Our primers confirmed their specificity for detecting the presence of T.cruzi.
文摘在高中电化学学习里,学生的学习由宏观层面进入抽象的微观领域,考验学生的具体形象思维和抽象逻辑思维的相互转换能力。基于OBE理论(Outcome based education又称为成果导向教育、目标导向教育)的教学方法重视学生的个性化发展,能够让学生获得持久性理解知识。本文将OBE教育理念与高中电化学的大单元教学进行结合,提出了确定目标和学习成果、重视实践应用、团队合作和交流、多元化教学方法的对策。希望为教师在电化学教学时提供更为有效和科学的教学方法和策略,提高学生的学习效果。
文摘目的探究重症监护室(intensive care unit,ICU)糖尿病酮症酸中毒患者应用胰岛素不同给药方式的作用效果。方法回顾性选取2023年4月—2024年5月上海市第六人民医院福建医院收治的88例ICU糖尿病酮症酸中毒患者的临床资料,根据不同治疗方式分为对照组(n=44,多次静脉滴注小剂量胰岛素)、观察组(n=44,微量输液泵持续泵入胰岛素)。比较两组临床疗效、糖代谢指标、不良反应发生率。结果观察组治疗总有效率高于对照组,治疗15 d后的餐后2 h血糖、空腹血糖、糖化血红蛋白水平以及不良反应发生率均低于对照组,差异有统计学意义(P均<0.05)。结论ICU糖尿病酮症酸中毒注射胰岛素时选择微量输液泵持续泵入方式,可提高治疗有效率,增强控糖效果,降低不良反应的发生。
文摘For high viscosity bulk-copolymerization of octamethylcyclotetrasiloxane and amino-silicone monomer, a multisyphon flow physical model was established.Based on the free volume and chemical reaction kinetic theories, a new computational model was developed to simulate the multisyphon flow model. As to the new model, the united influence of reaction and diffusion was reviewed and analyzed. The new model was used to simulate bulk- copolymerization of octamethylcyclotetrasiloxane and amino-silicone monomer and agreed well with the results.