The effect of pre-irradiation on radiation sensitivity of fiber Bragg gratings （FBGs） is verified experimentally. FBGs are fabricated in photosensitive optical fibers and single mode fibers with Ce-concentration in ...The effect of pre-irradiation on radiation sensitivity of fiber Bragg gratings （FBGs） is verified experimentally. FBGs are fabricated in photosensitive optical fibers and single mode fibers with Ce-concentration in a range from 3 mol% to 23.37 mol% in the core. In experiments, the FBGs are subjected to twice v-radiation exposures to a Co^60 source at a dose-rate of 0.1 Gy/s up to a total dose of 50 kGy. Pre-irradiation treatment can reduce the temperature sensitivity variation of FBGs by 18.12%-35.91%, as well as Bragg wavelength shift （BWS） by 8%-27.08 %. Our research demonstrates that pre-irradiation treatment is a feasible method to improve the radiation tolerance of FBGs.展开更多
Summary： The HL-60 cells were transfected with chkl antisense and sense chain, and 24 h later subjected to irradiation. Twenty-four h after irradiation, the changes in the chk1 protein expression was assayed by Weste...Summary： The HL-60 cells were transfected with chkl antisense and sense chain, and 24 h later subjected to irradiation. Twenty-four h after irradiation, the changes in the chk1 protein expression was assayed by Western blot, and the cell cycles and apoptosis rate detected by FCM. The irradiated apoptosis sensitivity was increased by antisense blocking of chk1 gene in HL-60 cell line with the apoptosis rate being 26.31 %, significantly higher than that by the sense blocking （10.34 %, 0. 025〈P〈0.05）. In HL-60 cells transfected with chkl antisense chain, the G2/M phase arrest was attenua：ted and the cells in G2/M phase were accounted for 38.42 %, significantly lower than those of the cells transfected with chkl sense chain （54.64 %, 0. 005〈P〈0.01）. It was concluded that antisense blocking of chk1 gene could increase the apoptosis sensitivity to irradiation.展开更多
The IAP AGCM was used to simulate the climate of 125kyr and 115kyr before present. We analysed the results and then studied the sensitivity of the model to the changes of radiation distribution induced by orbital para...The IAP AGCM was used to simulate the climate of 125kyr and 115kyr before present. We analysed the results and then studied the sensitivity of the model to the changes of radiation distribution induced by orbital parameter changes. The reasonability of the results was also discussed.展开更多
基金Project supported by the National Natural Science Foundation of China (Grant No. 61007040)the Fundamental Research Funds for Central Universities
文摘The effect of pre-irradiation on radiation sensitivity of fiber Bragg gratings （FBGs） is verified experimentally. FBGs are fabricated in photosensitive optical fibers and single mode fibers with Ce-concentration in a range from 3 mol% to 23.37 mol% in the core. In experiments, the FBGs are subjected to twice v-radiation exposures to a Co^60 source at a dose-rate of 0.1 Gy/s up to a total dose of 50 kGy. Pre-irradiation treatment can reduce the temperature sensitivity variation of FBGs by 18.12%-35.91%, as well as Bragg wavelength shift （BWS） by 8%-27.08 %. Our research demonstrates that pre-irradiation treatment is a feasible method to improve the radiation tolerance of FBGs.
文摘Summary： The HL-60 cells were transfected with chkl antisense and sense chain, and 24 h later subjected to irradiation. Twenty-four h after irradiation, the changes in the chk1 protein expression was assayed by Western blot, and the cell cycles and apoptosis rate detected by FCM. The irradiated apoptosis sensitivity was increased by antisense blocking of chk1 gene in HL-60 cell line with the apoptosis rate being 26.31 %, significantly higher than that by the sense blocking （10.34 %, 0. 025〈P〈0.05）. In HL-60 cells transfected with chkl antisense chain, the G2/M phase arrest was attenua：ted and the cells in G2/M phase were accounted for 38.42 %, significantly lower than those of the cells transfected with chkl sense chain （54.64 %, 0. 005〈P〈0.01）. It was concluded that antisense blocking of chk1 gene could increase the apoptosis sensitivity to irradiation.
文摘The IAP AGCM was used to simulate the climate of 125kyr and 115kyr before present. We analysed the results and then studied the sensitivity of the model to the changes of radiation distribution induced by orbital parameter changes. The reasonability of the results was also discussed.
