Potential of non-Western medicines in chemoradiotherapy for cervical cancer

This editorial explores the potential integration of non-Western medicine into radiotherapy for cervical cancer.While radiotherapy remains a radical treatment for cervical cancer,its associated toxicity and decline in quality of life can significantly impact patients’lives.Currently,most treatments are supportive,with no specific treatment options available in Western medicine.Non-Western medicine,often less toxic and easier to administer,has shown promising results when used alongside radiotherapy for cervical cancer.Despite these potential benefits,challenges such as limited evidence and restricted application areas persist.While non-Western medicines may offer potential improvements in chemoradiotherapy outcomes for cervical cancer,further research is necessary to substantiate these benefits.

AES-192的相关密钥飞去来器攻击和矩形攻击

相关密钥攻击是对AES十分有效的分析方法之一.在2022年亚密会上,Derbez等利用概率为2−108的10轮相关密钥飞去来器区分器给出了目前最好的AES-192的全轮攻击.本文改进了全轮AES-192的相关密钥飞去来器和矩形攻击.基于Wang等的9轮相关密钥飞去来器区分器的截断差分,本文利用飞去来器分布表(BDT)技术给出目前概率最高的10轮相关密钥飞去来器区分器,概率为2−105.92.基于该区分器,改进了全轮AES-192的相关密钥飞去来器攻击,时间、数据和存储复杂度分别为2^(121.92)、2^(121.92)和2^(90.92),与之前的结果相比时间复杂度改进了22.08.进一步,给出了全轮AES-192的相关密钥矩形攻击,时间、数据和存储复杂度分别为2^(127.9)、2^(119.5)和2^(131.5),这也是目前在选择明文模式下对全轮AES-192最好的攻击结果.

基于AES的车联网通信加密算法

随着V2X技术发展得越来越快,车辆与其他设备的通信量以及信息重要度都在急速增长,车载信息遭到攻击从而被截取或者发生泄漏的风险也相应地大大增加,因此信息交互安全性成为了一个不可避免的研究课题。本文针对车联网传输数据量大、数据加解密操作频繁等问题,通过分析经典加密算法,进而改进传统AES加密算法,使用RC4加密算法生成伪随机密钥代替AES加密算法的密钥生成模块,优化加密时间的同时提升安全性能,并开展实验验证了其加密效率以及安全性。

基于AES与ECC混合算法的计算机网络通信数据安全加密方法

为了提高通信数据在计算机网络中的安全性,提出一种基于AES与ECC混合算法的计算机网络通信数据安全加密方法。通过时域分析,得到通信数据在计算机网络边缘的频率分布情况,根据通信数据中冗余信息的密度,离散化处理通信数据内的噪声,提取出通信数据的特征向量。根据通信数据的明文空间进行加密处理,计算出待加密通信数据的密文值,将计算机网络通信数据的加密过程约束成加密函数的计算,设定通信数据安全加密的约束条件,采用AES算法加密通信数据的明文,利用ECC算法加密AES密钥,将AES与ECC结合,生成通信数据的密钥密文,实现通信数据的安全加密。实验结果表明,所提方法能够保证通信数据在计算机网络中的安全,可以将通信数据加密后的受攻击指数控制在0.1以内,提高通信数据的加密效果。

基于LSTM-AE的民机空调热交换器性能异常检测方法

空调热交换器性能异常检测技术是快速判断民机空调系统运行状态并合理安排维修任务的关键,传统的异常检测方法难以有效处理高维时序数据,无法实现系统早期故障预警。为此,本文提出了一种基于长短期记忆网络(LSTM,long-short term memory)与自编码器(AE,autoencoder)模型的无监督异常检测方法,用以识别民机空调系统异常运行状态。首先,基于民机空调系统原始传感器参数构建表征空调热交换器性能的特征监测参数;其次,构建LSTM-AE模型进行数据特征重构并计算重构误差;最后,使用孤立森林(iForest, isolation forest)进行无监督异常监测。将本文构建的无监督异常检测方法与传统方法对比,并建立模型评估指标,验证结果表明,所构建的模型方法可以对民机空调热交换器性能异常状态进行有效检测。

基于混沌序列和AES算法的数据库外层数据传输同步加密方法

为保障数据库外层数据的安全传输,提出一种基于混沌序列和AES算法的数据库外层数据传输同步加密方法。该方法结合AES算法的加密安全性和混沌序列的加密速度优势,通过加密代理服务器和应用服务器对数据库外层数据进行处理,利用混沌序列logistic映射参数初始化、混沌序列二进制量化、AES动态加密和尾端处理实现数据库外层数据传输同步加密。实验结果表明,该方法能够成功地对文本和图像数据进行加密和隐藏,同时提高加密效率,并兼顾了数据的安全性和传输效率。

基于AES算法的计算机数据库加密系统设计与实现

随着信息技术的迅猛发展,中等职业(中职)教育面临着教学资源更新和个性化教学需求的双重挑战。知识图谱是一种通过链接和整合广泛信息资源来创建、利用和分享知识的技术,能够在复杂的数据中寻找规律,为用户提供准确的信息推荐服务。研究通过分析数据库加密的常用方式和数据库透明加密(TDE)原理,设计了一套基于知识图谱的中职线上教学资源推荐系统的体系架构。系统采用高级加密标准(AES)算法加密设计保证数据安全,整合数据库提升系统效能,并详细说明了开发过程的实现。通过实验结果及分析,证明了系统的有效性和实用性,为中职教育提供了一种新的线上教学资源推荐解决方案。

Concurrent chemoradiotherapy combined with enteral nutrition support:a radical treatment strategy for esophageal squamous cell carcinoma patients with malignant istulae

Background: Concurrent chemoradiotherapy(CCRT) significantly increases the survival rate of esophageal squa?mous cell carcinoma(ESCC) patients with malignant fistulae. Recent clinical evidence has shown the benefits of enteral nutrition for malnourished cancer patients. In this study, we aimed to validate that, with the support of enteral nutrition, ESCC patients who develop malignant fistulae might be able to complete CCRT and achieve long?term survival.Methods: We reviewed the medical records of 652 patients with ESCC who received definitive CCRT at Sun Yat?sen University Cancer Center between January 2010 and December 2012. Treatment outcome and toxicity were ret?rospectively evaluated in 40 ESCC patients with malignant fistulae. All the 40 patients were treated with CCRT and evaluated by clinical nutritionists using nutrition risk screening(NRS) before, during, and after treatment. Twenty?two patients received a nasogastric tube, and 18 underwent percutaneous endoscopic gastrostomy feeding. The median energy intake was 2166 kcal/day. Treatment response was evaluated at 3 months after the completion of CCRT.Results: With a median follow?up of 18 months(range, 3–39 months), patients' 1?year overall survival(OS) rate was 62.5%, and the estimated OS time was 25.5 months. Univariate analysis showed that the NRS score(P n NRS score(P se to treatment(P < 0.001) were sig= 0.003), increase i= 0.024), fistula closure(P = 0.011), and responnifi?cantly associated with OS. Multivariate analysis showed that tumor response(P = 0.044) and increase in NRS score(P = 0.044) were independent predictors of OS. Grade 3 vomiting was observed in 8 patients(20.0%), grade 3 neutro?penia was observed in 11 patients(27.5%), and grade 3 cough was observed in 13 patients(32.5%); 2 patients(5.0%) died of massive bleeding during treatment.Conclusions: CCRT combined with enteral nutrition support is effective for ESCC patients with malignant fistulae. Patients have an increased potential to be cured, especially those who experience complete response and have an increase in NRS score. Careful observation and nutrition support are required for patients with advanced T?category ESCC who undergo CCRT.

ICP-AES法测定电炉渣中二氧化硅

本文研究了采用酸溶的方式消解样品,ICP-AES光谱法测定电炉渣中二氧化硅的分析方法。采用浓盐酸和浓硝酸溶解电炉尾料样品,加入氢氟酸消解二氧化硅和硼酸络合氟离子,采用ICP-AES法测定电炉尾料样品中的二氧化硅含量。二氧化硅的相对标准偏差RSD为0.35%~0.58%,加标回收率为95.6%~102.3%。方法加标回收率好,满足分析方法要求。

基于单通道AE盲源分离的结构损伤定位

声发射(acoustic emission,简称AE)能够实现复杂板状结构损伤定位,但多数AE检测定位方法仅针对单AE源的情况,而实际中复杂板状结构产生损伤时会伴随多个AE卷积混合信号。为了解决工程中多AE源定位的问题,提出一种单通道AE盲分离-模态提取定位方法。首先,对采集的AE信号进行信号降噪,使用单通道盲源分离算法分离出无回波成分的AE信号,将多源定位转为多个单源定位问题;其次,通过提取单频模态,求取声波传播速度,估计到达时间差来进行疲劳裂纹损伤定位;最后,经过计算机仿真实验和钢箱梁桥断铅半实物仿真实验,验证了方法的准确性和有效性,并通过载荷破坏AE检测实验验证了方法的实用性。结果表明,所提方法能够应用于复杂板状结构多AE源定位问题,为实际工程应用提供了可靠的依据及参考价值。

电感耦合等离子体原子发射光谱(ICP-AES)法测定真空精炼镁合金物料中铁、铜、镍

真空精炼是目前镁金属提纯的重要工艺,工艺原料及真空精炼提纯镁金属过程残留物中Fe、Cu、Ni含量的准确测定对工艺参数的优化及调整具有重要的指导作用。传统测定方法中以邻二氮杂菲分光光度法、新亚铜灵分光光度法、丁二酮肟分光光度法测定三种元素含量,结果准确,但操作繁琐,周期较长,难以满足工业生产中高效、快速测定的需要,且方法中所需的有机萃取剂对环境污染较大。选择电感耦合等离子体发射光谱(ICP-AES)法测定真空蒸馏精炼镁合金物料中Fe、Cu、Ni,系统探究溶解酸、溶解温度、溶解时间对物料溶解和测定的影响,选择盐酸(1+1)和过氧化氢溶解体系,200℃加热条件下反应20 min为最佳消解镁合金原料条件;选择王水溶解体系,200℃加热条件下反应25 min为真空精炼残留物最佳溶解条件。并探讨ICP-AES测定过程中各元素的检出限和测定下限以及共存元素的干扰情况,建立了ICP-AES法测定真空精炼提纯镁合金物料的方法。测定结果的相对标准偏差(RSD,n=11)为Fe 5.9%~11.5%、Cu 2.6%~11.8%、Ni 3.4%~11.5%,各元素加标回收率为Fe 96.4%~102%、Cu 101%~108%、Ni 103%~105%;按照建立的方法测定镁合金原料、真空精炼残留物中的铁、铜、镍,并与国家标准方法测定结果进行对比,结果相一致。实现了ICP-AES法快速、准确测定真空蒸馏精炼镁合金物料中铁、铜、镍含量,对及时、高效、准确评估真空精炼提纯镁工艺及产品具有重要意义。

Stereotactic body radiotherapy in pancreatic adenocarcinoma

Background:Stereotactic body radiotherapy(SBRT)in pancreatic cancer allows high delivery of radiation doses on tumors without affecting surrounding tissue.This review aimed at the SBRT application in the treatment of pancreatic cancer.Data sources:We retrieved articles published in MEDLINE/PubMed from January 2017 to December 2022.Keywords used in the search included:“pancreatic adenocarcinoma”OR“pancreatic cancer”AND“stereotactic ablative radiotherapy(SABR)”OR“stereotactic body radiotherapy(SBRT)”OR“chemoradiotherapy(CRT)”.English language articles with information on technical characteristics,doses and fractionation,indications,recurrence patterns,local control and toxicities of SBRT in pancreatic tumors were included.All articles were assessed for validity and relevant content.Results:Optimal doses and fractionation have not yet been defined.However,SBRT could be the standard treatment in patients with pancreatic adenocarcinoma in addition to CRT.Furthermore,the combination of SBRT with chemotherapy may have additive or synergic effect on pancreatic adenocarcinoma.Conclusions:SBRT is an effective modality for patients with pancreatic cancer,supported by clinical practice guidelines as it has demonstrated good tolerance and good disease control.SBRT opens a possibility of improving outcomes for these patients,both in neoadjuvant treatment and with radical intent.

AE81镁合金轧制变形显微组织演变的研究

通过重力铸造法制备了AE81稀土镁合金,并对固溶处理后的合金在300℃和350℃进行压下量分别为15%、20%、25%和30%的轧制变形。结果表明:稀土元素Ce的加入导致铸态组织中Mg_(17)Al_(12)相不连续分布,镁基体上分布的Al4Ce相以块状形貌、中空管状形貌和针状形貌存在。轧制变形后,AE81合金所产生的变形组织的体积分数随着压下量的增大而增大,当压下量增大到25%时出现了明显的动态再结晶现象,再结晶晶粒的平均尺寸主要分布在200~400nm之间,且动态再结晶区域主要分布在Al_(4)Ce相周围。同时,Mg_(17)Al_(12)析出相的体积分数随着轧制温度和压下量的增大而增大,Mg_(17)Al_(12)相在基体上的分布得到改善。

Present situation and prospect of immunotherapy for unresectable locally advanced esophageal cancer during peri-radiotherapy

Four major studies(Checkmate577,Keynote-590,Checkmate649 and Attraction-4)of locally advanced esophageal cancer published in 2020 have established the importance of immunotherapy,represented by anti-programmed death protein(PD)-1 in postoperative adjuvant treatment and advanced first-line treatment of locally advanced or advanced esophageal cancer and esophagogastric junction cancer,from the aspects of proof of concept,long-term survival,overall survival rate and progression-free survival.For unresectable or inoperable nonmetastatic esophageal cancer,concurrent radiotherapy and chemotherapy is the standard treatment recommended by various guidelines.Because its curative effect is still not ideal,it is necessary to explore radical radiotherapy and chemotherapy in the future,and it is considered to be promising to combine them with immunotherapeutic drugs such as anti-PD-1.This paper mainly discusses how to combine radical concurrent radiotherapy and chemotherapy with immunotherapy for unresectable local advanced esophageal cancer.

基于FPGA的AES和ECC算法图像加密

随着数字图像的使用次数日益增多,保护机密图像数据免受未经授权的访问较为重要。针对数字图像在通信、存储和传输等领域存在的安全问题,文中基于对称算法模型和非对称算法模型的优点提出一种具有高安全性和高速度性的数字信封技术密码方案。该方案以AES(Advanced Encryption Standard)和ECC(Elliptic Curve Cryptography)为基础,经优化后用于对称密钥共享的ECC硬件架构来提高密钥的安全性。通过加入伪随机数、使用列移位替代列混淆运算以及三维S-box等方式对传统AES进行优化,在保持香农扩散和混淆原理的同时降低了时间复杂性。基于FPGA(Field Programmable Gate Array)实现AES算法的数字图像加密仿真以及性能测试。测试结果表明,所提密码方案具有快速性、高安全性和有效性等优点,能够有效地实现图像加密。

基于AES的改进视频加密测试

为了使得视频加密技术具有更加良好的加密效果,在原本AES加密算法基础上进行了创新,通过加密元素的选取、运动矢量的加密方案设计、DCT变化系数的加密方案设计三部分进行了展开分析与实验;经过后续仿真验证,密钥敏感性得到了很好的提升;视频质量方面,改进后的AES算法的RGB直方图可知其加密效果和解密还原效果良好,经过对比分析,改进后的AES算法加密的SSIM值最小、PSNR值更低,即加密效果相对更好;经过计算可知,编码时间百分比增加了0.23%,解码时间百分比增加了8.56%,对NPCR、UACI以及加密前后视频帧像素对的相关系数等参数分别测试可知,相比前人的几种加密方式,改进后视频加密安全性能最好;综上分析可知,改进后视频加密效果最好。

基于优化AE数学模型的计算机网络风险检测与评估方法

针对现有网络风险评估方法存在的精度低、偏差大等问题,提出一种基于优化AE数学模型的计算机网络风险检测与评估方法。定义风险项参数并根据风险等级确定评估结果,推导风险项处理条件并确定风险项;结合风险特征提取结果,分别求解风险性检测值与风险性评估值,进而提升计算机网络风险检测与评估的精度。实验结果表明,所提方法可将偶发性风险的传输范围控制在0~5.12×10^(15)bit,有助于合理控制偶发性风险因素,确保网络系统稳定运行。

基于AES加密的区块链节点授信与身份共识研究

节点授信和身份共识是区块链的核心,为保证区块链的运行安全,确保全网数据的一致性,提出基于AES加密的区块链节点授信与身份共识方法。在区块链环境下,收集区块链节点历史行为数据,利用AES加密生成区块链节点密钥对。综合考虑区块链节点信任度的测算结果和密钥对的生成结果,验证区块链节点身份。根据节点身份,授予节点的信任权限,实现区块链网络中节点之间快速达成身份共识。通过实证分析实验得出结论:与传统方法相比,优化设计方法下区块链节点的授信风险降低了0.41,同时节点身份验证成功率得到明显提升。

CAEFusion: A New Convolutional Autoencoder-Based Infrared and Visible Light Image Fusion Algorithm

To address the issues of incomplete information,blurred details,loss of details,and insufficient contrast in infrared and visible image fusion,an image fusion algorithm based on a convolutional autoencoder is proposed.The region attention module is meant to extract the background feature map based on the distinct properties of the background feature map and the detail feature map.A multi-scale convolution attention module is suggested to enhance the communication of feature information.At the same time,the feature transformation module is introduced to learn more robust feature representations,aiming to preserve the integrity of image information.This study uses three available datasets from TNO,FLIR,and NIR to perform thorough quantitative and qualitative trials with five additional algorithms.The methods are assessed based on four indicators:information entropy(EN),standard deviation(SD),spatial frequency(SF),and average gradient(AG).Object detection experiments were done on the M3FD dataset to further verify the algorithm’s performance in comparison with five other algorithms.The algorithm’s accuracy was evaluated using the mean average precision at a threshold of 0.5(mAP@0.5)index.Comprehensive experimental findings show that CAEFusion performs well in subjective visual and objective evaluation criteria and has promising potential in downstream object detection tasks.

Radiotherapy for hyoid bone metastasis from lung adenocarcinoma:A case report

BACKGROUND Metastasis to the hyoid bone is an exceptionally rare occurrence,with documented cases limited to breast,liver,colon,skin,lung,and prostate cancers.This report highlights an unusual case involving the metastasis of lung adenocarcinoma to the hyoid bone,accompanied by a distinctive headache.Previous documentation involved surgical resection of the hyoid mass.We present a case displaying the benefits of palliative radiotherapy.CASE SUMMARY A 72-year-old non-smoking,non-alcoholic woman,initially under investigation for a year-long elevation in absolute lymphocyte count,presented with a monthlong history of intermittent throat pain.Despite negative findings in gastroenterological and otolaryngologic examinations,a contrast-enhanced chest computed tomography scan revealed a mediastinal mass and questionable soft tissue thickening in her left anterolateral neck.Subsequent imaging and biopsies confirmed the presence of lung adenocarcinoma metastasis to the hyoid bone.The patient was treated with platinum-based chemo-immunotherapy along with pembrolizumab.Ultimately,the lung cancer was unresponsive.Our patient opted for palliative radiation therapy instead of surgical resection to address her throat pain.As a result,her throat pain was alleviated,and it also incidentally resolved her chronic headaches.This is the second documented case of lung adenocarcinoma metastasizing to the hyoid bone.CONCLUSION Palliative radiotherapy may add to the quality of life in symptomatic patients with cancer metastatic to the hyoid bone.