Objective Individuals with pulmonary hypertension(PH)have reduced exercise capacity and quality of life.Exercise-based rehabilitation may have beneficial effects to improve the exercise capacity and quality of life in...Objective Individuals with pulmonary hypertension(PH)have reduced exercise capacity and quality of life.Exercise-based rehabilitation may have beneficial effects to improve the exercise capacity and quality of life in patients with PH.We aim to assess the efficacy and safety of exercised-based rehabilitation for people eith PH by performing a randomized controlled trails(RCTs)meta-analysis of exercised-based rehabilitation for people with PH by performing a randomized controlled trails meta-analysis.展开更多
Abducens nerve palsy(ANP) is commonly seen in patients with diabetes mellitus. The validity of acupuncture as a traditional Chinese medicine method in peripheral nerve repair is well established. However, its effica...Abducens nerve palsy(ANP) is commonly seen in patients with diabetes mellitus. The validity of acupuncture as a traditional Chinese medicine method in peripheral nerve repair is well established. However, its efficacy in randomized controlled trials remains unclear. Herein, we designed a protocol for a prospective, single-center, randomized controlled trial to investigate the effect of intraorbital electroacupuncture on diabetic ANP. We plan to recruit 60 patients with diabetic ANP, and randomly divide them into treatment and control groups. Patients in both groups will continue their glucose-lowering therapy. A neural nutrition drug will be given to both groups for six weeks. The treatment group will also receive intraorbital electroacupuncture therapy. We will assess efficacy of treatment, eyeball movement, diplopia deviation and the levels of fasting blood-glucose and glycosylated hemoglobin before treatment at 2, 4, and 6 weeks after treatment. The efficacy and recurrence will be investigated during follow-up(1 month after intervention). This protocol was registered at Chinese Clinical Trial Registry on 16 January 2015(Chi CTR-IPR-15005836). This study was approved by the Ethics Committee of First Affiliated Hospital of Harbin Medical University of China(approval number: 201452). All protocols will be in accordance with Declaration of Helsinki, formulated by the World Medical Association. Written informed consent will be provided by participants. We envisage that the results of this clinical trial will provide evidence for promoting clinical use of this new therapy for management of ANP.展开更多
Objective: To compare the efficacy of a short messaging service (SMS) text messaging and phone reminder to im-prove attendance rates at a health promotion center. Methods: A total of 1 859 participants who had schedul...Objective: To compare the efficacy of a short messaging service (SMS) text messaging and phone reminder to im-prove attendance rates at a health promotion center. Methods: A total of 1 859 participants who had scheduled appointments in the health promotion center of our hospital from April 2007 to May 2007 were enrolled in the study and randomly assigned into 3 groups: control (no reminder) group,SMS text messaging reminder group and telephone reminder group. Attendance rates and costs of interventions were collected. Results: A total of 1848 participants were eligible for analysis. Attendance rates of control,SMS and telephone groups were 80.5%,87.5% and 88.3%,respectively. The attendance rates were significantly higher in SMS and telephone groups than that in the control group,with odds ratio 1.698,95% confidence interval 1.224 to 2.316,P=0.001 in the SMS group,and odds ratio 1.829,95% confidence interval 1.333 to 2.509,P<0.001 in the telephone group. However,there was no difference between the SMS group and the telephone group (P=0.670). The cost effectiveness analysis showed that the cost per attendance for the SMS group (0.31 Yuan) was significantly lower than that for the telephone group (0.48 Yuan). Conclusion: SMS and telephone are effective reminders for improving attendance rate at a health promotion center. SMS reminder may be more cost-effective compared with the telephone reminder.展开更多
Pharmaco-psychosocial treatment (PPST) refers to a treatment paradigm combining pharmacotherapy with psychosocial therapy. We conducted an 18-month randomized controlled tracking study to evaluate the efficacy of soci...Pharmaco-psychosocial treatment (PPST) refers to a treatment paradigm combining pharmacotherapy with psychosocial therapy. We conducted an 18-month randomized controlled tracking study to evaluate the efficacy of social skills training (SST) in 11 individuals with schizophrenia on risperidone monotherapy. They were randomized to either SST or non-SST group, and Global Assessment Functioning (GAF) and Brief Psychiatric Rating Scale (BPRS) scores in the 2 groups showed gradual improvement. In the SST group, Digit Span Distraction Test (DSDT) at 12 and 18 months showed significant improvement. The Subjective Deficit Syndrome Scale (SDSS) scores in the SST group showed significant improvement after 6 months and showed a significant difference in comparison between the groups. After the subjective feeling of health was recovered, the items of motivation were recovered as a direct effect of SST. Some items of the Life Assessment Scale for the Mentally Ill (LASMI) score showed significant improvement (or significant trend) in only the SST group after 6 months. Items of daily life, work skills, and self-recognition were continuously improved. We report 2 cases in the SST group that had DSDT improvement in parallel with change of action and communication as a change of social function. This study is only exploratory due to the small number of cases. However, we have demonstrated potential improvement in cognitive function due to learning experiences that required working memory and attention, thus providing improvement in social life.展开更多
Objective To observe the clinical effect of acupuncture in combination with medicine in the treatment of mild cognitive impairment after cerebral infarction as well as the impact on patients' daily living ability. Me...Objective To observe the clinical effect of acupuncture in combination with medicine in the treatment of mild cognitive impairment after cerebral infarction as well as the impact on patients' daily living ability. Methods Seventy-two patients, in accordance with random number table, were divided into two groups, acupuncture combined with western medicine group (group A) and western medicine group (group B), each group with 36 patients. In combination with nimodipine tablets, acupuncture which can regulate the mind and reinforce the intelligence [making Baihui (百会 GV 20), Sishencong (四神聪EX-HN 1), Sibai (四白 ST 2), Fengchi (风池 GB 20), Wanggu (完骨 GB 12), Tianzhu (天柱 BL 10), Shenmen (神门 HT 7), Neiguan (内关 PC 6), Shuigou (水沟 GV 26), Sanyinjiao (三阴交 SP 6), Taichong (太冲 LR 3), Fenglong (丰隆 ST 40) as the main acupoints] was given in the treatment group (group A) while only nimodipine tablets were given in the control group (group B). The efficacy of these two groups was evaluated by Montreal Cognitive Assessment (MoCA) Scale after the continuous treatment for three months. Results The remarkably effective rate was 69.4%.and the total effective rate was 91.7% in the treatment group, while the remarkably effective rate was 55.6% and the total effective rate was 80.6% in the control group; the differences between the two groups were statistically significant (P〈0.05). When comparing the MoCA score before and after treatment, which was 20.23±4.67 before treatment and 26.84±3.87 after treatment in group A; 19.82±3.56 before treatment and 23.33±2.78 after treatment in group B, it was found that the score for both groups became higher after treatment than that before treatment. Furthermore, the increase of the score was higher in the treatment group (6.61±0.80) than that in the control group (3.51±0.78) and the differences were statistically significant (P〈0.05). Conclusion Acupuncture, which can regulate the mind and reinforce the intelligence, combined with nimodipine tablets is an effective therapy for the treatment of mild cognitive impairment after cerebral infarction, which is superior to single treatment with nimodipine tablets.展开更多
OBJECTIVE:To observe the curative effect of an acupoint application with a Dingqi analgesic patch on moderate to severe pain caused by liver cancer.METHODS:Forty patients with moderate to severe pain caused by liver c...OBJECTIVE:To observe the curative effect of an acupoint application with a Dingqi analgesic patch on moderate to severe pain caused by liver cancer.METHODS:Forty patients with moderate to severe pain caused by liver cancer were randomly divided intoatreatmentgroup(TG)andacontrolgroup(CG).Patients with moderate pain were given 100 mg qd of a sustainably released tablet of tramadol hydrochloride;patientswithseverepainweregiven4.2mg q3d of the fentanyl transdermal system.The ashi points Ganshu(BL 18),Danshu(BL 19) and Qimen(LR 14) were chosen for the acupoint application intervention.CG patients were given a sham patch and TG patients were given a Dingqi analgesic patch.A visual analogue scale(VAS) was used before treatment and after 1,3,6,9 and 12 days of treatment.The Karnofsky score was measured before treatment and after 12 days of treatment.Any main adverse reactions(e.g.nausea,constipation,dizziness and headache) were recorded after 6 and 12 days of treatment.Any skin side effects(i.e.skin irritation and allergic reactions) were recorded.RESULTS:The VAS in TG was significantly lower than that in CG after 3,6,9 and 12 days of treatment(P<0.05).There was no significant difference in the Karnofsky score before treatment and after 12 days of treatment between CG and TG.There were also no significant differences in the main adverse reactions or skin side effects after 6 and 12 days of treatment between CG andTG(P>0.05).CONCLUSION:The Dingqi analgesic patch can enhance the analgesic effect of tramadol and fentanyl.展开更多
OBJECTIVE: To analyze the effect of needling acupoints(bilateral vs unilateral) with De Qi using data collected from 501 primary dysmenorrhea(PD) patients participating in multi-center, randomized,controlled trail.MET...OBJECTIVE: To analyze the effect of needling acupoints(bilateral vs unilateral) with De Qi using data collected from 501 primary dysmenorrhea(PD) patients participating in multi-center, randomized,controlled trail.METHODS: De Qi was defined as at least one of the feelings in soreness, numbness, fullness or heaviness at the acupoints when stimulated with needles. The 501 patients were grouped in 3 groups in terms of De Qi or not De Qi in one side(unilateral)or both sides(bilateral) of the body: bilateral De Qi group, unilateral De Qi group, and non-De Qi group. The abdominal pains were measured using visual analog scale(VAS).RESULTS: In 501 patients, 472 acquired De Qi at unilateral acupoints, 24 De Qi at bilateral acupoint,and 5 had no De Qi at any acupoint. The data of non-De Qi group was excluded as the sample was less than 5% of that in the bilateral De Qi group.There was significant difference in the VAS before and after treatment between unilateral and bilateral De Qi group(P < 0.01). After stratified by acupoints, for the patients needled at Sanyinjiao(SP 6)and Xuanzhong(GB 39), VAS scores in the bilateral De Qi group were larger than those in the unilateral De Qi group(P < 0.05).CONCLUSION: Bilateral De Qi was possibly superior to unilateral De Qi in enhancing the immediate analgesic effect of needling the acupoints, but no statistical significance was observed on the pa-tients of needling at non acupoint, which preliminarily suggested this immediate analgesic effect was perhaps along meridians.展开更多
Objective To observe the clinical efficacy of acupuncture combined with speech rehabilitation training for post-stroke spasmodic dysphonia and compare the differences in efficacy among the therapy of acupuncture combi...Objective To observe the clinical efficacy of acupuncture combined with speech rehabilitation training for post-stroke spasmodic dysphonia and compare the differences in efficacy among the therapy of acupuncture combined with speech rehabilitation training and the monotherapy.Methods Two hundred and seventy cases of patients with post-stroke spasmodic dysarthria were randomly divided into three groups with the ratio of 1:1:1.Group A:acupuncture combined with speech rehabilitation training group(90 cases),group B:acupuncture group(90 cases),group C:speech rehabilitation training group(90 cases).In the group B,acupuncture treatment was given at Baihui(百会 GV 20),JTnjin(金津 EX-HN 12) and Yuye(玉液 EX-HN13) as well as tongue-three needles.In the group C,the treatment of speech rehabilitation training was provided.The two treatments mentioned above were combined in the group A.Patients were treated once a day for a month with improved Frenchay dysarthria rating scale as the indices of therapeutic effect evaluation.Results ① Group A:the cured and markedly effective rate was 88.7%,and total effective rate was 94.3%;group B:the cured and markedly effective rate was 44.2%and total effective rate was 81.4%;group C:the cured and markedly effective rate was 23.5%and total effective rate was 61.2%.Both the cured and markedly effective rate and the total effective rate in the group A were significantly higher than those in the group B or group C(all P0.05);both the cured and markedly effective rate and the total effective rate in the group B were higher than those of group C(both P0.05);② In comparison of functional recovery of tongue in accordance with the Frenchay dysarthria rating scale,the recovery rate of the tongue-stationary state was 71.74%in the group A,18.87%in the group B and 4.44%in the group C;the recovery rate of tongue lolling out was 66.23%in the group A,27.63%in the group B and 1.59%in the group C;the recovery rate of tongue up and down motion was 44.19%in the group A,4.94%in the group B and 1.35%in the group C;the recovery rate of lateral motion was 40.24%in the group A,7.59%in the group B and 0.00%in the group C;the recovery rate of alternating motion was 29.07%in the group A,7.14%in the group B and 1.23%in the group C;the recovery rate of speech was 29.07%in the group A,5.88%in the group B and 1.22%in the group C.In the three groups,the recovery rates of stationary state and tongue lolling out were superior to those of up and down movement,lateral movement,alternating movement and speech(all P0.05).Conclusion The clinical efficacy of acupuncture combined with speech rehabilitation training for patients with post-stroke spasmodic dysarthria is significant,and the efficacy of acupuncture is superior to that of speech rehabilitation training;as for functional recovery of tongue like stationary state and tongue out,the therapy of acupuncture combined with speech rehabilitation training is effective.展开更多
Objective To observe the clinical effect of acupoint catgut embedding combined with abdominal acupuncture for treatment of abdominal obesity under the theoretical guidance of regulating the three energizer.Methods One...Objective To observe the clinical effect of acupoint catgut embedding combined with abdominal acupuncture for treatment of abdominal obesity under the theoretical guidance of regulating the three energizer.Methods One hundred and twenty patients were randomly divided into acupoint catgut embedding group(group A),abdominal acupuncture group(group B),acupoint catgut embedding combined with abdominal acupuncture group(group C) and blank control group(group D) based on blocked random method,with 30 cases each;the first three groups based on the principle of regulating three energizer were respectively given acupoint catgut embedding at Zhongwan(中脘 CV12),Tianshu(天枢 ST 25),Yinjiao(阴交 CV 7),Zhigou(支沟 TE 6),Guanyuan(关元 CV 4),Zusanli(足三里 ST 36) with catgut embedding once every 7 days,three times for each course of treatment,abdominal acupuncture once every3 days,seven times for each course of treatment.Results The therapeutic effect of each group after treatment was respectively 46.7%(14/30),43.3%(13/30),76.7%(23/30) and 26.7%(8/30),with statistically significant difference.For comparison of waist circumference difference,there was no statistical significance between acupoint catgut embedding combined with abdominal acupuncture and acupoint catgut embedding group(P=0.54),and for comparison of weight difference,there was statistical significance in terms of therapeutic effect between acupoint catgut embedding combined with abdominal acupuncture and A,B,D groups(4.49±0.59 vs 2.64±0.53,2.87±0.44,1.45±0.26,all P〈0.05).Conclusion Acupoint catgut embedding combined with abdominal acupuncture had the best effect in terms of total effective rate for treatment of abdominal obesity,equivalent therapeutic effect to simple acupoint catgut embedding in terms of waist circumference reduction,and the best therapeutic effect in terms of weight reduction.展开更多
Objective To explore the best intervention time of peripheral facial paralysis (Bell' s palsy) treated with acupuncture-moxibustion and the clinical superiority of acupuncture-moxibustion by stages. Methods Multi- ...Objective To explore the best intervention time of peripheral facial paralysis (Bell' s palsy) treated with acupuncture-moxibustion and the clinical superiority of acupuncture-moxibustion by stages. Methods Multi- central large-sample randomized controlled trial was carried out. Nine hundred cases of Bell' s palsy were randomly divided into 5 treatment groups, named as acupuncture by stages group, acupuncture by stages with moxibustion group, acupuncture by stages with electroacupuncture group, acupuncture by stages with line-puncture on muscle region of meridian group and acupuncture without stages group. Four sessions of treatment were required in each group. The clinical curative effects of groups were assessed by House-Brackmann Scale, Facial Disability Index Scale and Degree of Facial Nerve Paralysis Scale during the enrollment, after 4 sessions of treatment, and during 1 and 3 months of follow-up after treatment. The systematic analysis of curative effects was provided in view of the intervention time and nerve localization of disease separately. Results The cure rates of intervention treatment were 50.1% (223/445) in acute stage and 52.1% (162/311) in resting stage, superior to that of 25.9% (35/135) in recovery stage (both P〈0.001). There was no statistically significant differences in comparison of curative effect in 5 solutions at the same stage (all P〉0.05). The effect of treatment intervened at acute stage was superior to that at recovery stage in acupuncture by stages group and acupuncture without stages group (both P〈0.01). There were statistically significant differences in curative effect of the localization above and below chorda tympani nerve in acupuncture by stages with line-puncture on muscle region of meridian group (P〈0.01). The curative effect of the localization below chorda tympani nerve was superior to that above the nerve. Conclusion The best intervention time for Bell' s palsy is at acute stage and resting stage, meaning 1 to 3 weeks after occurrence. All 5 solutions are clinical superiorities to Bell's palsy. Under the condition of limited medical sources, the simple filiform needle puncture is recommended at acute stage. For the patients with the disorder above chorda tympani nerve, line-puncture on muscle region of meridian is not recommended.展开更多
Objective To investigate the effect of moxibustion at Sanyinjiao (三阴交 SP 6) for uterine contraction pain in labor, and evaluate the safety of the parturient and newborn. Methods One hundred and seventy-four cases...Objective To investigate the effect of moxibustion at Sanyinjiao (三阴交 SP 6) for uterine contraction pain in labor, and evaluate the safety of the parturient and newborn. Methods One hundred and seventy-four cases of singleton pregnancy and cephalic presentation primipara were single blinded and randomly divided into three groups: observation group (59 cases), placebo treated group (57 cases) and blank group (58 cases).The observation group was treated with moxibustion at Sanyinjiao (三阴交 SP 6) for 30 min when the uterus cervix openning at 3 cm,the placebo treated group was treated with moxibustion at non-aeupoint for 30 min and the blank group was treated with routine labor nursing, the uterine contraction pain and the safety of the mother and infant were compared among three groups. Results (1) The uterine contraction pain was tested by Visual Analogue Scale (VAS): the scores of VAS in the observation group were obviously decreased after 15 min and 30 min of moxibustion (both P〈0.05), there were no obvious changes of the VAS scores in placebo treated group and the blank group, the scores of VAS in observation group decreased much more obviously than those in the other two groups (all P〈0.05); (2)Midwife rating of the uterine contraction pain: after 30 min of moxibustion, the effective rate of labor analgesia was 69.5%(41/59) in observation group, which was higher than that of 45.6% (26/57) in placebo treated group and 43.1% (25/58) in blank group, with significant differences between them (both P〈0.05); @The postpartum hemorrhage amount of the observation group was obviously lower than those of placebo treated group and blank group (both P〈0.05); (4)The Apgar score of newborn was higher in observation group and placebo treated group than that of blank group (both P〈0.05). Conclusion Moxibustion at Sanyinjiao (三阴交 SP 6) can relieve the uterine contraction pain, and has no side effect to mother and infant, it is one of the safe, effective and simple non-drug analgesia methods.展开更多
Objective To observe the therapeutic effect of acupuncture treatment for chronic fatigue syndrome (CFS). Methods Ninety cases of CFS were randomly divided into an observation group and a control group, 45 cases in e...Objective To observe the therapeutic effect of acupuncture treatment for chronic fatigue syndrome (CFS). Methods Ninety cases of CFS were randomly divided into an observation group and a control group, 45 cases in each group. The observation group was treated with acupuncture at Renying (人迎 ST 9), Fengfu(风府 GV 16), Batihui (百会 GV 20); the control group was treated with 250 mL 5% Glucose injeetio combined with 20 mL Shenmai injectio (参脉注射液). Fatigue Scale (FS) was used to compare the scores between the two groups after treatment. Results The total scores in the observation group ,were 9.37±2.33 and 5.41±1.96 before and after treatment respectively, and in the control group, they were 9.08±2.27 and 7.34±2.03 respectively. FS brainwork integral, physical fatigue integral, and total integral all decreased after treatment in two groups (all P〈0.001), and it decreased much more obviously in the observation group (P〈0.05, P〈0.01). Conclusion Both of the acupuncture treatment and Shenmai injectio are able to decrease Fatigue Scale score, improve the fatigue symptoms of CFS patients, and the effect of acupuncture treatment is obviously superior to that of Shenmai injectio.展开更多
Objective To observe the therapeutic effect of moxibustion on pain, stiffness and physical dysfunction caused by knee osteoarthritis (KOA), and make an assessment on the effectiveness and safety of this therapy. Met...Objective To observe the therapeutic effect of moxibustion on pain, stiffness and physical dysfunction caused by knee osteoarthritis (KOA), and make an assessment on the effectiveness and safety of this therapy. Methods Fifty-nine cases of KOA were randomly divided into a moxibustion group (31 cases) and a sham-moxibustion group (28 cases). The treatment of moxibustion was given at Nèixīyǎn (内膝眼 EX-LE 4), Dúbí (犊鼻 ST 35) and Ashi points with real moxa cone in the moxibustion group and sham moxa cone in the sham-moxibustion group, 3 cones on each point per time, once every two days, 3 times per week for consecutively 6 weeks. The results were recorded in week 3 and 6 of the treatment, and the follow-up visit was performed 6 weeks after the end of treatment. The Western Ontario and Mcmaster Universities Osteoarthritis Index (WOMAC) and the shortest walking time of 46 m were adopted to evaluate the recovery situation of joint function. The UT-325 digital thermal detector was put to use to record the temperature change in the most obvious painful points of knee joint before and after the moxibustion. Results All the scores of WOMAC in the moxibustion group were apparently decreased in week 3 and 6 of the treatment as well as the follow-up visit, separately (P〈0.05, P〈0.01, P〈0.001). The stiffness score of follow-up visit in the sham-moxibustion group, compared before the treatment, was lowered (P〈0.05). The scores of pain, stiffness and physical function in the moxibustion group had a greater decrease than those in the sham-moxibustion group in week 6 of treatment and the follow-up visit (P〈0.01, P〈0.05). The shortest walking time of 46 m in the moxibustion group after 6 weeks of the treatment was apparently reduced as compared with that before treatment (P〈0.01), but there was no apparent improvement in the sham-moxibustion group (P〉0.05), and the between-group difference was not significant statistically (P〉0.05). The temperature of treatment point after the moxibustion was (49.81±3.10)?℃ in the moxibustion group and (40.98±1.67)?℃ in the sham-moxibustion group, which was both increased apparently as compared with that before the treatment (P〈0.001, P〈0.01), and more obviously in the moxibustion group (P〈0.001). Conclusion The moxibustion, which can obviously improve the clinical symptoms of the patients with KOA, such as pain, stiffness and physical dysfunction, is safe and effective.展开更多
Objective To observe the clinical efficacy of the needling method for regulating wei qi and strengthening brain on insomnia.Method Two hundred patients with insomnia were randomly divided into a group of regulating we...Objective To observe the clinical efficacy of the needling method for regulating wei qi and strengthening brain on insomnia.Method Two hundred patients with insomnia were randomly divided into a group of regulating wei qi and strengthening brain(group A) and a group of normal acupuncture(group B)through random number table method,with 100 cases in each group.In group A,Baihui(百会 GV20),Dazhui(大椎 GV 14),Shenmai(申脉 BL62),Zhaohai(照海 KI 6) and auricular points Yuanzhong(缘中 AT 2,3,4i),and Shenmen(神门TF 4) were selected;and in group B,Sishencong(四神聪 EX-HN 1),Shenmen(神门 HT 7),and Sanyinjiao(三阴交 SP 6) were selected.Acupuncture was given on these points once daily for 15 days.Pittsburgh sleep quality index(PSQI) was used for scoring and curative effect was evaluated before and after treatment.Results The total effective rate was 89.0%(89/100) in group A and 65.0%(65/100) in group B with a very significant difference between the two groups(P〈0.01);the difference of PSQI scores before and after treatment was(-9.15±5.68)in group A and(-5.64±5.73)in group B,with a very significant difference before and after treatment in the two groups(P〈0.01).Conclusion The therapeutic effect of the needling method for regulating wei qi and strengthening brain on insomnia is superior to that of normal needling method.展开更多
Objective To compare the efficacy differences between acupuncture and western medicine in treating osteoarthritis of knee joints.Methods One hundred and twenty cases were randomly divided into an acupuncture group and...Objective To compare the efficacy differences between acupuncture and western medicine in treating osteoarthritis of knee joints.Methods One hundred and twenty cases were randomly divided into an acupuncture group and a western medication group with 60 cases in each group.In the acupuncture group,acupuncture was applied mainly at Nèixīyǎn(内膝眼 EX-LE 4),Dúbí(犊鼻 ST 35),Yīnlíngquán(阴陵泉 SP 9) and Yánglíngquán(阳陵泉 GB 34) plus other acupoints selected according to syndrome differentiation.In the medication group,Glucosamine Hydrochloride capsules were orally given 3 times daily with 2 capsules each time.Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC),Medical Outcomes Study 36-Item Short Form Health Survey(SF-36,Chinese version) were used to assess therapeutic effects before treatment,after 4 weeks treatment and 9 weeks after treatment,respectively.Results After 4 weeks of treatment,the total effective rates were 86.7%(52/60) and 88.3%(53/60) in the acupuncture group and the western medication group,respectively,without significant difference(P〈0.05).In 9 weeks after treatment,the total effective rates were 83.3%(50/60) and 61.7%(37/60) in the acupuncture group and the western medication group,respectively,with significant difference between the two groups(P〈0.05).According to WOMAC and SF-36,the scores were all improved in both groups(P〈0.05,P〈0.01),with significant difference in follow-up visit of 9 weeks after treatment between the two groups(P〈0.05,P〈0.01),but not after 4 weeks of treatments(both P〈0.05).Conclusion Short-term of therapeutic effects of acupuncture and oral administration of Glucosamine Hydrochloride on osteoarthritis of knee joints are similar,but long-term efficacy in the acupuncture group is better than that in the western medication group.展开更多
Objective To explore the feasibility of electroacupuncture compound anesthesia in radiofrequency ablation for hypertrophic inferior turbinate.Methods The patients confirmed to the enrolled criteria were randomly divid...Objective To explore the feasibility of electroacupuncture compound anesthesia in radiofrequency ablation for hypertrophic inferior turbinate.Methods The patients confirmed to the enrolled criteria were randomly divided into an observation group(n=31) and a control group(n=30).In the observation group,electroacupuncture was applied to Sìbái(四白 ST 2),Xiàguān(下关 ST 7),Hégǔ(合谷 LI 4) and Zhīgōu(支沟 TE 6) on the left side for the anesthesia and the routine local anesthesia was done on the right side.In the control group,the routine local anesthesia was adopted on both sides.The feelings of pain,circulatory index and operation effect were observed and compared between the two groups.Results During radiofrequency ablation,the pain grades of two measurements on the left side and the 2nd measurement on the right in the observation group were all lower than those in the control group(all P〈0.05).In the observation group,the pain grade on the left side was lower than that on the right side(P〈0.05),and the systolic blood pressure and the heart rate were lower than those in the control group when undergoing the 2nd radiofrequency ablation on the right side and on the left side,respectively(all P〈0.05).There was no significant difference in operation effect between the two groups.Conclusion Electroacupuncture compound anesthesia can meet the analgesia requirement of radiofrequency ablation for hypertrophic inferior turbinate,and would be helpful to prevent cyclic fluctuation during the operation at the same time.展开更多
Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-str...Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-stroke patients with upper limb spasticity were randomly divided into two groups at the ratio of 1: 1, the group of meridian sinew row needling combined with dermal needling (group A, 244 cases) and western medication group (group B, 244 cases). Coupled with rehabilitation, the patients in the group A were given meridian sinew row needling combined with dermal needling where five shu points were specifically selected, and three yang meridians of the hand were treated with acupuncture with muscle region, and three yin meridians of the hand were treated with dermal needles; the patients in the group B was treated with conventional western medication with piracetam injection and cerebroprotein hydrolysate included. Clinical efficacy was evaluated among patients in the two groups after three weeks of continuous treatment, and upper limb spasticity and motor functions were observed through modified Asworth Scale and FugI-Meyer Assessment Scale (FMA) before and after treatment. Results For Asworth Scale, group A was significantly superior to group B (3.04 ± 1.29 vs 3.88 ± 1.54, P〈0.05); for FMA scale, group A was also significantly superior to group B (48.67± 15.64 vs 42.96±14.72, P〈0.05); mitigations of motor status of upper limb joints in group A, such as remission of shoulder adduction (90.5%), pronation of forearm (70.7%), elbow joint flexion (73.1%), wrist joint flexion (80.9%) and finger flexion (88.1%), were superior to those of group B (70.0%, 60.0%, 61.9%, 57.4%, 63.2%, all P〈0.05). Conclusion Good clinical efficacy of the treatment with combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis is achieved.展开更多
文摘Objective Individuals with pulmonary hypertension(PH)have reduced exercise capacity and quality of life.Exercise-based rehabilitation may have beneficial effects to improve the exercise capacity and quality of life in patients with PH.We aim to assess the efficacy and safety of exercised-based rehabilitation for people eith PH by performing a randomized controlled trails(RCTs)meta-analysis of exercised-based rehabilitation for people with PH by performing a randomized controlled trails meta-analysis.
基金supported by the National Natural Science Foundation of China,No.81674052the Key Project of Natural Science Foundation of Heilongjiang Province of China,No.ZD201211a grant from the Project of Innovational Scientific Research of Harbin Medical University of China,No.2016LCZX49
文摘Abducens nerve palsy(ANP) is commonly seen in patients with diabetes mellitus. The validity of acupuncture as a traditional Chinese medicine method in peripheral nerve repair is well established. However, its efficacy in randomized controlled trials remains unclear. Herein, we designed a protocol for a prospective, single-center, randomized controlled trial to investigate the effect of intraorbital electroacupuncture on diabetic ANP. We plan to recruit 60 patients with diabetic ANP, and randomly divide them into treatment and control groups. Patients in both groups will continue their glucose-lowering therapy. A neural nutrition drug will be given to both groups for six weeks. The treatment group will also receive intraorbital electroacupuncture therapy. We will assess efficacy of treatment, eyeball movement, diplopia deviation and the levels of fasting blood-glucose and glycosylated hemoglobin before treatment at 2, 4, and 6 weeks after treatment. The efficacy and recurrence will be investigated during follow-up(1 month after intervention). This protocol was registered at Chinese Clinical Trial Registry on 16 January 2015(Chi CTR-IPR-15005836). This study was approved by the Ethics Committee of First Affiliated Hospital of Harbin Medical University of China(approval number: 201452). All protocols will be in accordance with Declaration of Helsinki, formulated by the World Medical Association. Written informed consent will be provided by participants. We envisage that the results of this clinical trial will provide evidence for promoting clinical use of this new therapy for management of ANP.
基金Project supported by the Health Promotion Center of Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, China
文摘Objective: To compare the efficacy of a short messaging service (SMS) text messaging and phone reminder to im-prove attendance rates at a health promotion center. Methods: A total of 1 859 participants who had scheduled appointments in the health promotion center of our hospital from April 2007 to May 2007 were enrolled in the study and randomly assigned into 3 groups: control (no reminder) group,SMS text messaging reminder group and telephone reminder group. Attendance rates and costs of interventions were collected. Results: A total of 1848 participants were eligible for analysis. Attendance rates of control,SMS and telephone groups were 80.5%,87.5% and 88.3%,respectively. The attendance rates were significantly higher in SMS and telephone groups than that in the control group,with odds ratio 1.698,95% confidence interval 1.224 to 2.316,P=0.001 in the SMS group,and odds ratio 1.829,95% confidence interval 1.333 to 2.509,P<0.001 in the telephone group. However,there was no difference between the SMS group and the telephone group (P=0.670). The cost effectiveness analysis showed that the cost per attendance for the SMS group (0.31 Yuan) was significantly lower than that for the telephone group (0.48 Yuan). Conclusion: SMS and telephone are effective reminders for improving attendance rate at a health promotion center. SMS reminder may be more cost-effective compared with the telephone reminder.
文摘Pharmaco-psychosocial treatment (PPST) refers to a treatment paradigm combining pharmacotherapy with psychosocial therapy. We conducted an 18-month randomized controlled tracking study to evaluate the efficacy of social skills training (SST) in 11 individuals with schizophrenia on risperidone monotherapy. They were randomized to either SST or non-SST group, and Global Assessment Functioning (GAF) and Brief Psychiatric Rating Scale (BPRS) scores in the 2 groups showed gradual improvement. In the SST group, Digit Span Distraction Test (DSDT) at 12 and 18 months showed significant improvement. The Subjective Deficit Syndrome Scale (SDSS) scores in the SST group showed significant improvement after 6 months and showed a significant difference in comparison between the groups. After the subjective feeling of health was recovered, the items of motivation were recovered as a direct effect of SST. Some items of the Life Assessment Scale for the Mentally Ill (LASMI) score showed significant improvement (or significant trend) in only the SST group after 6 months. Items of daily life, work skills, and self-recognition were continuously improved. We report 2 cases in the SST group that had DSDT improvement in parallel with change of action and communication as a change of social function. This study is only exploratory due to the small number of cases. However, we have demonstrated potential improvement in cognitive function due to learning experiences that required working memory and attention, thus providing improvement in social life.
基金Supported by Special Research Project for Practice Development of National TCM Clinical Research Base,State Administration of Traditional Chinese Medicine(JDZX 2012139)
文摘Objective To observe the clinical effect of acupuncture in combination with medicine in the treatment of mild cognitive impairment after cerebral infarction as well as the impact on patients' daily living ability. Methods Seventy-two patients, in accordance with random number table, were divided into two groups, acupuncture combined with western medicine group (group A) and western medicine group (group B), each group with 36 patients. In combination with nimodipine tablets, acupuncture which can regulate the mind and reinforce the intelligence [making Baihui (百会 GV 20), Sishencong (四神聪EX-HN 1), Sibai (四白 ST 2), Fengchi (风池 GB 20), Wanggu (完骨 GB 12), Tianzhu (天柱 BL 10), Shenmen (神门 HT 7), Neiguan (内关 PC 6), Shuigou (水沟 GV 26), Sanyinjiao (三阴交 SP 6), Taichong (太冲 LR 3), Fenglong (丰隆 ST 40) as the main acupoints] was given in the treatment group (group A) while only nimodipine tablets were given in the control group (group B). The efficacy of these two groups was evaluated by Montreal Cognitive Assessment (MoCA) Scale after the continuous treatment for three months. Results The remarkably effective rate was 69.4%.and the total effective rate was 91.7% in the treatment group, while the remarkably effective rate was 55.6% and the total effective rate was 80.6% in the control group; the differences between the two groups were statistically significant (P〈0.05). When comparing the MoCA score before and after treatment, which was 20.23±4.67 before treatment and 26.84±3.87 after treatment in group A; 19.82±3.56 before treatment and 23.33±2.78 after treatment in group B, it was found that the score for both groups became higher after treatment than that before treatment. Furthermore, the increase of the score was higher in the treatment group (6.61±0.80) than that in the control group (3.51±0.78) and the differences were statistically significant (P〈0.05). Conclusion Acupuncture, which can regulate the mind and reinforce the intelligence, combined with nimodipine tablets is an effective therapy for the treatment of mild cognitive impairment after cerebral infarction, which is superior to single treatment with nimodipine tablets.
基金Supported by the Administration of Traditional Chinese Medicine of Guangdong Province,China (No. 2010431)
文摘OBJECTIVE:To observe the curative effect of an acupoint application with a Dingqi analgesic patch on moderate to severe pain caused by liver cancer.METHODS:Forty patients with moderate to severe pain caused by liver cancer were randomly divided intoatreatmentgroup(TG)andacontrolgroup(CG).Patients with moderate pain were given 100 mg qd of a sustainably released tablet of tramadol hydrochloride;patientswithseverepainweregiven4.2mg q3d of the fentanyl transdermal system.The ashi points Ganshu(BL 18),Danshu(BL 19) and Qimen(LR 14) were chosen for the acupoint application intervention.CG patients were given a sham patch and TG patients were given a Dingqi analgesic patch.A visual analogue scale(VAS) was used before treatment and after 1,3,6,9 and 12 days of treatment.The Karnofsky score was measured before treatment and after 12 days of treatment.Any main adverse reactions(e.g.nausea,constipation,dizziness and headache) were recorded after 6 and 12 days of treatment.Any skin side effects(i.e.skin irritation and allergic reactions) were recorded.RESULTS:The VAS in TG was significantly lower than that in CG after 3,6,9 and 12 days of treatment(P<0.05).There was no significant difference in the Karnofsky score before treatment and after 12 days of treatment between CG and TG.There were also no significant differences in the main adverse reactions or skin side effects after 6 and 12 days of treatment between CG andTG(P>0.05).CONCLUSION:The Dingqi analgesic patch can enhance the analgesic effect of tramadol and fentanyl.
基金Supported by National Basic Research Program of China(973 Program)-the Effect of De Qi on Acupoint Specific Effect Based on Meridians and its Characteristics and Molecular Response Mechanisms(No.2012CB518506)Research on Acupoint Specificity in Regulating Uterus(No.2006CB504503)+2 种基金Research on Laws of Acupoint Effects(No.2005CB523308)National Natural Science Foundation of China Traditional Acupuncture Formula for Inducing Labor(Hegu-Sanyinjiao,LI4-SP6)Electro-acupuncture Parameter Optimization and Molecular Response Mechanisms(No.30973793)the Doctoral Program of Higher Education of Ministry Education of China-Research Based on Primary Dysmenorrhea on Electric Characteristics of Acupoints Which Were Different Ones on the Same Meridians or Similar Ones on the Different Meridians(No.20090013110005)
文摘OBJECTIVE: To analyze the effect of needling acupoints(bilateral vs unilateral) with De Qi using data collected from 501 primary dysmenorrhea(PD) patients participating in multi-center, randomized,controlled trail.METHODS: De Qi was defined as at least one of the feelings in soreness, numbness, fullness or heaviness at the acupoints when stimulated with needles. The 501 patients were grouped in 3 groups in terms of De Qi or not De Qi in one side(unilateral)or both sides(bilateral) of the body: bilateral De Qi group, unilateral De Qi group, and non-De Qi group. The abdominal pains were measured using visual analog scale(VAS).RESULTS: In 501 patients, 472 acquired De Qi at unilateral acupoints, 24 De Qi at bilateral acupoint,and 5 had no De Qi at any acupoint. The data of non-De Qi group was excluded as the sample was less than 5% of that in the bilateral De Qi group.There was significant difference in the VAS before and after treatment between unilateral and bilateral De Qi group(P < 0.01). After stratified by acupoints, for the patients needled at Sanyinjiao(SP 6)and Xuanzhong(GB 39), VAS scores in the bilateral De Qi group were larger than those in the unilateral De Qi group(P < 0.05).CONCLUSION: Bilateral De Qi was possibly superior to unilateral De Qi in enhancing the immediate analgesic effect of needling the acupoints, but no statistical significance was observed on the pa-tients of needling at non acupoint, which preliminarily suggested this immediate analgesic effect was perhaps along meridians.
文摘Objective To observe the clinical efficacy of acupuncture combined with speech rehabilitation training for post-stroke spasmodic dysphonia and compare the differences in efficacy among the therapy of acupuncture combined with speech rehabilitation training and the monotherapy.Methods Two hundred and seventy cases of patients with post-stroke spasmodic dysarthria were randomly divided into three groups with the ratio of 1:1:1.Group A:acupuncture combined with speech rehabilitation training group(90 cases),group B:acupuncture group(90 cases),group C:speech rehabilitation training group(90 cases).In the group B,acupuncture treatment was given at Baihui(百会 GV 20),JTnjin(金津 EX-HN 12) and Yuye(玉液 EX-HN13) as well as tongue-three needles.In the group C,the treatment of speech rehabilitation training was provided.The two treatments mentioned above were combined in the group A.Patients were treated once a day for a month with improved Frenchay dysarthria rating scale as the indices of therapeutic effect evaluation.Results ① Group A:the cured and markedly effective rate was 88.7%,and total effective rate was 94.3%;group B:the cured and markedly effective rate was 44.2%and total effective rate was 81.4%;group C:the cured and markedly effective rate was 23.5%and total effective rate was 61.2%.Both the cured and markedly effective rate and the total effective rate in the group A were significantly higher than those in the group B or group C(all P0.05);both the cured and markedly effective rate and the total effective rate in the group B were higher than those of group C(both P0.05);② In comparison of functional recovery of tongue in accordance with the Frenchay dysarthria rating scale,the recovery rate of the tongue-stationary state was 71.74%in the group A,18.87%in the group B and 4.44%in the group C;the recovery rate of tongue lolling out was 66.23%in the group A,27.63%in the group B and 1.59%in the group C;the recovery rate of tongue up and down motion was 44.19%in the group A,4.94%in the group B and 1.35%in the group C;the recovery rate of lateral motion was 40.24%in the group A,7.59%in the group B and 0.00%in the group C;the recovery rate of alternating motion was 29.07%in the group A,7.14%in the group B and 1.23%in the group C;the recovery rate of speech was 29.07%in the group A,5.88%in the group B and 1.22%in the group C.In the three groups,the recovery rates of stationary state and tongue lolling out were superior to those of up and down movement,lateral movement,alternating movement and speech(all P0.05).Conclusion The clinical efficacy of acupuncture combined with speech rehabilitation training for patients with post-stroke spasmodic dysarthria is significant,and the efficacy of acupuncture is superior to that of speech rehabilitation training;as for functional recovery of tongue like stationary state and tongue out,the therapy of acupuncture combined with speech rehabilitation training is effective.
文摘Objective To observe the clinical effect of acupoint catgut embedding combined with abdominal acupuncture for treatment of abdominal obesity under the theoretical guidance of regulating the three energizer.Methods One hundred and twenty patients were randomly divided into acupoint catgut embedding group(group A),abdominal acupuncture group(group B),acupoint catgut embedding combined with abdominal acupuncture group(group C) and blank control group(group D) based on blocked random method,with 30 cases each;the first three groups based on the principle of regulating three energizer were respectively given acupoint catgut embedding at Zhongwan(中脘 CV12),Tianshu(天枢 ST 25),Yinjiao(阴交 CV 7),Zhigou(支沟 TE 6),Guanyuan(关元 CV 4),Zusanli(足三里 ST 36) with catgut embedding once every 7 days,three times for each course of treatment,abdominal acupuncture once every3 days,seven times for each course of treatment.Results The therapeutic effect of each group after treatment was respectively 46.7%(14/30),43.3%(13/30),76.7%(23/30) and 26.7%(8/30),with statistically significant difference.For comparison of waist circumference difference,there was no statistical significance between acupoint catgut embedding combined with abdominal acupuncture and acupoint catgut embedding group(P=0.54),and for comparison of weight difference,there was statistical significance in terms of therapeutic effect between acupoint catgut embedding combined with abdominal acupuncture and A,B,D groups(4.49±0.59 vs 2.64±0.53,2.87±0.44,1.45±0.26,all P〈0.05).Conclusion Acupoint catgut embedding combined with abdominal acupuncture had the best effect in terms of total effective rate for treatment of abdominal obesity,equivalent therapeutic effect to simple acupoint catgut embedding in terms of waist circumference reduction,and the best therapeutic effect in terms of weight reduction.
基金Supported by 11th Five-Year Plan for Science and Technology Project: 2006 BAI 12 B 03
文摘Objective To explore the best intervention time of peripheral facial paralysis (Bell' s palsy) treated with acupuncture-moxibustion and the clinical superiority of acupuncture-moxibustion by stages. Methods Multi- central large-sample randomized controlled trial was carried out. Nine hundred cases of Bell' s palsy were randomly divided into 5 treatment groups, named as acupuncture by stages group, acupuncture by stages with moxibustion group, acupuncture by stages with electroacupuncture group, acupuncture by stages with line-puncture on muscle region of meridian group and acupuncture without stages group. Four sessions of treatment were required in each group. The clinical curative effects of groups were assessed by House-Brackmann Scale, Facial Disability Index Scale and Degree of Facial Nerve Paralysis Scale during the enrollment, after 4 sessions of treatment, and during 1 and 3 months of follow-up after treatment. The systematic analysis of curative effects was provided in view of the intervention time and nerve localization of disease separately. Results The cure rates of intervention treatment were 50.1% (223/445) in acute stage and 52.1% (162/311) in resting stage, superior to that of 25.9% (35/135) in recovery stage (both P〈0.001). There was no statistically significant differences in comparison of curative effect in 5 solutions at the same stage (all P〉0.05). The effect of treatment intervened at acute stage was superior to that at recovery stage in acupuncture by stages group and acupuncture without stages group (both P〈0.01). There were statistically significant differences in curative effect of the localization above and below chorda tympani nerve in acupuncture by stages with line-puncture on muscle region of meridian group (P〈0.01). The curative effect of the localization below chorda tympani nerve was superior to that above the nerve. Conclusion The best intervention time for Bell' s palsy is at acute stage and resting stage, meaning 1 to 3 weeks after occurrence. All 5 solutions are clinical superiorities to Bell's palsy. Under the condition of limited medical sources, the simple filiform needle puncture is recommended at acute stage. For the patients with the disorder above chorda tympani nerve, line-puncture on muscle region of meridian is not recommended.
基金Supported by Tangshan Science and Technology Research and Development Projects: 08130206CScience and Technology Research Program Projects of Hebei CM Administration Bureau: 2009055
文摘Objective To investigate the effect of moxibustion at Sanyinjiao (三阴交 SP 6) for uterine contraction pain in labor, and evaluate the safety of the parturient and newborn. Methods One hundred and seventy-four cases of singleton pregnancy and cephalic presentation primipara were single blinded and randomly divided into three groups: observation group (59 cases), placebo treated group (57 cases) and blank group (58 cases).The observation group was treated with moxibustion at Sanyinjiao (三阴交 SP 6) for 30 min when the uterus cervix openning at 3 cm,the placebo treated group was treated with moxibustion at non-aeupoint for 30 min and the blank group was treated with routine labor nursing, the uterine contraction pain and the safety of the mother and infant were compared among three groups. Results (1) The uterine contraction pain was tested by Visual Analogue Scale (VAS): the scores of VAS in the observation group were obviously decreased after 15 min and 30 min of moxibustion (both P〈0.05), there were no obvious changes of the VAS scores in placebo treated group and the blank group, the scores of VAS in observation group decreased much more obviously than those in the other two groups (all P〈0.05); (2)Midwife rating of the uterine contraction pain: after 30 min of moxibustion, the effective rate of labor analgesia was 69.5%(41/59) in observation group, which was higher than that of 45.6% (26/57) in placebo treated group and 43.1% (25/58) in blank group, with significant differences between them (both P〈0.05); @The postpartum hemorrhage amount of the observation group was obviously lower than those of placebo treated group and blank group (both P〈0.05); (4)The Apgar score of newborn was higher in observation group and placebo treated group than that of blank group (both P〈0.05). Conclusion Moxibustion at Sanyinjiao (三阴交 SP 6) can relieve the uterine contraction pain, and has no side effect to mother and infant, it is one of the safe, effective and simple non-drug analgesia methods.
基金Supported by Guangdong Science-Technology Program Project:K 2060032
文摘Objective To observe the therapeutic effect of acupuncture treatment for chronic fatigue syndrome (CFS). Methods Ninety cases of CFS were randomly divided into an observation group and a control group, 45 cases in each group. The observation group was treated with acupuncture at Renying (人迎 ST 9), Fengfu(风府 GV 16), Batihui (百会 GV 20); the control group was treated with 250 mL 5% Glucose injeetio combined with 20 mL Shenmai injectio (参脉注射液). Fatigue Scale (FS) was used to compare the scores between the two groups after treatment. Results The total scores in the observation group ,were 9.37±2.33 and 5.41±1.96 before and after treatment respectively, and in the control group, they were 9.08±2.27 and 7.34±2.03 respectively. FS brainwork integral, physical fatigue integral, and total integral all decreased after treatment in two groups (all P〈0.001), and it decreased much more obviously in the observation group (P〈0.05, P〈0.01). Conclusion Both of the acupuncture treatment and Shenmai injectio are able to decrease Fatigue Scale score, improve the fatigue symptoms of CFS patients, and the effect of acupuncture treatment is obviously superior to that of Shenmai injectio.
基金Supported by National 973 Project: 2009 CB 522901The Leading Academic Discipline Project of State Administra on of TCM and the City of Shanghai: S 30304The Scienfic and Technological Brainstorm Project of Shanghai: 11 DZ 1973300, 11 ZR 1436700
文摘Objective To observe the therapeutic effect of moxibustion on pain, stiffness and physical dysfunction caused by knee osteoarthritis (KOA), and make an assessment on the effectiveness and safety of this therapy. Methods Fifty-nine cases of KOA were randomly divided into a moxibustion group (31 cases) and a sham-moxibustion group (28 cases). The treatment of moxibustion was given at Nèixīyǎn (内膝眼 EX-LE 4), Dúbí (犊鼻 ST 35) and Ashi points with real moxa cone in the moxibustion group and sham moxa cone in the sham-moxibustion group, 3 cones on each point per time, once every two days, 3 times per week for consecutively 6 weeks. The results were recorded in week 3 and 6 of the treatment, and the follow-up visit was performed 6 weeks after the end of treatment. The Western Ontario and Mcmaster Universities Osteoarthritis Index (WOMAC) and the shortest walking time of 46 m were adopted to evaluate the recovery situation of joint function. The UT-325 digital thermal detector was put to use to record the temperature change in the most obvious painful points of knee joint before and after the moxibustion. Results All the scores of WOMAC in the moxibustion group were apparently decreased in week 3 and 6 of the treatment as well as the follow-up visit, separately (P〈0.05, P〈0.01, P〈0.001). The stiffness score of follow-up visit in the sham-moxibustion group, compared before the treatment, was lowered (P〈0.05). The scores of pain, stiffness and physical function in the moxibustion group had a greater decrease than those in the sham-moxibustion group in week 6 of treatment and the follow-up visit (P〈0.01, P〈0.05). The shortest walking time of 46 m in the moxibustion group after 6 weeks of the treatment was apparently reduced as compared with that before treatment (P〈0.01), but there was no apparent improvement in the sham-moxibustion group (P〉0.05), and the between-group difference was not significant statistically (P〉0.05). The temperature of treatment point after the moxibustion was (49.81±3.10)?℃ in the moxibustion group and (40.98±1.67)?℃ in the sham-moxibustion group, which was both increased apparently as compared with that before the treatment (P〈0.001, P〈0.01), and more obviously in the moxibustion group (P〈0.001). Conclusion The moxibustion, which can obviously improve the clinical symptoms of the patients with KOA, such as pain, stiffness and physical dysfunction, is safe and effective.
基金Supported by Project of State Administration of Traditional Chinese Medicine:2002 ZL 29
文摘Objective To observe the clinical efficacy of the needling method for regulating wei qi and strengthening brain on insomnia.Method Two hundred patients with insomnia were randomly divided into a group of regulating wei qi and strengthening brain(group A) and a group of normal acupuncture(group B)through random number table method,with 100 cases in each group.In group A,Baihui(百会 GV20),Dazhui(大椎 GV 14),Shenmai(申脉 BL62),Zhaohai(照海 KI 6) and auricular points Yuanzhong(缘中 AT 2,3,4i),and Shenmen(神门TF 4) were selected;and in group B,Sishencong(四神聪 EX-HN 1),Shenmen(神门 HT 7),and Sanyinjiao(三阴交 SP 6) were selected.Acupuncture was given on these points once daily for 15 days.Pittsburgh sleep quality index(PSQI) was used for scoring and curative effect was evaluated before and after treatment.Results The total effective rate was 89.0%(89/100) in group A and 65.0%(65/100) in group B with a very significant difference between the two groups(P〈0.01);the difference of PSQI scores before and after treatment was(-9.15±5.68)in group A and(-5.64±5.73)in group B,with a very significant difference before and after treatment in the two groups(P〈0.01).Conclusion The therapeutic effect of the needling method for regulating wei qi and strengthening brain on insomnia is superior to that of normal needling method.
文摘Objective To compare the efficacy differences between acupuncture and western medicine in treating osteoarthritis of knee joints.Methods One hundred and twenty cases were randomly divided into an acupuncture group and a western medication group with 60 cases in each group.In the acupuncture group,acupuncture was applied mainly at Nèixīyǎn(内膝眼 EX-LE 4),Dúbí(犊鼻 ST 35),Yīnlíngquán(阴陵泉 SP 9) and Yánglíngquán(阳陵泉 GB 34) plus other acupoints selected according to syndrome differentiation.In the medication group,Glucosamine Hydrochloride capsules were orally given 3 times daily with 2 capsules each time.Western Ontario and McMaster Universities Osteoarthritis Index(WOMAC),Medical Outcomes Study 36-Item Short Form Health Survey(SF-36,Chinese version) were used to assess therapeutic effects before treatment,after 4 weeks treatment and 9 weeks after treatment,respectively.Results After 4 weeks of treatment,the total effective rates were 86.7%(52/60) and 88.3%(53/60) in the acupuncture group and the western medication group,respectively,without significant difference(P〈0.05).In 9 weeks after treatment,the total effective rates were 83.3%(50/60) and 61.7%(37/60) in the acupuncture group and the western medication group,respectively,with significant difference between the two groups(P〈0.05).According to WOMAC and SF-36,the scores were all improved in both groups(P〈0.05,P〈0.01),with significant difference in follow-up visit of 9 weeks after treatment between the two groups(P〈0.05,P〈0.01),but not after 4 weeks of treatments(both P〈0.05).Conclusion Short-term of therapeutic effects of acupuncture and oral administration of Glucosamine Hydrochloride on osteoarthritis of knee joints are similar,but long-term efficacy in the acupuncture group is better than that in the western medication group.
基金Supported by Foundation Project in Guang'anmen Hospital,China Academy of Chinese Medical Sciences:2006 S 195
文摘Objective To explore the feasibility of electroacupuncture compound anesthesia in radiofrequency ablation for hypertrophic inferior turbinate.Methods The patients confirmed to the enrolled criteria were randomly divided into an observation group(n=31) and a control group(n=30).In the observation group,electroacupuncture was applied to Sìbái(四白 ST 2),Xiàguān(下关 ST 7),Hégǔ(合谷 LI 4) and Zhīgōu(支沟 TE 6) on the left side for the anesthesia and the routine local anesthesia was done on the right side.In the control group,the routine local anesthesia was adopted on both sides.The feelings of pain,circulatory index and operation effect were observed and compared between the two groups.Results During radiofrequency ablation,the pain grades of two measurements on the left side and the 2nd measurement on the right in the observation group were all lower than those in the control group(all P〈0.05).In the observation group,the pain grade on the left side was lower than that on the right side(P〈0.05),and the systolic blood pressure and the heart rate were lower than those in the control group when undergoing the 2nd radiofrequency ablation on the right side and on the left side,respectively(all P〈0.05).There was no significant difference in operation effect between the two groups.Conclusion Electroacupuncture compound anesthesia can meet the analgesia requirement of radiofrequency ablation for hypertrophic inferior turbinate,and would be helpful to prevent cyclic fluctuation during the operation at the same time.
基金Supported by Hebei Administration of Traditional Chinese Medicine(2009180)
文摘Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-stroke patients with upper limb spasticity were randomly divided into two groups at the ratio of 1: 1, the group of meridian sinew row needling combined with dermal needling (group A, 244 cases) and western medication group (group B, 244 cases). Coupled with rehabilitation, the patients in the group A were given meridian sinew row needling combined with dermal needling where five shu points were specifically selected, and three yang meridians of the hand were treated with acupuncture with muscle region, and three yin meridians of the hand were treated with dermal needles; the patients in the group B was treated with conventional western medication with piracetam injection and cerebroprotein hydrolysate included. Clinical efficacy was evaluated among patients in the two groups after three weeks of continuous treatment, and upper limb spasticity and motor functions were observed through modified Asworth Scale and FugI-Meyer Assessment Scale (FMA) before and after treatment. Results For Asworth Scale, group A was significantly superior to group B (3.04 ± 1.29 vs 3.88 ± 1.54, P〈0.05); for FMA scale, group A was also significantly superior to group B (48.67± 15.64 vs 42.96±14.72, P〈0.05); mitigations of motor status of upper limb joints in group A, such as remission of shoulder adduction (90.5%), pronation of forearm (70.7%), elbow joint flexion (73.1%), wrist joint flexion (80.9%) and finger flexion (88.1%), were superior to those of group B (70.0%, 60.0%, 61.9%, 57.4%, 63.2%, all P〈0.05). Conclusion Good clinical efficacy of the treatment with combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis is achieved.