Background Flavonoids from fruits, vegetables and plants have been widely studied on their improving lipidemia, anti-inflammation, anti-platelet aggregation and anti-oxidative activities. However, t know if flavonoids...Background Flavonoids from fruits, vegetables and plants have been widely studied on their improving lipidemia, anti-inflammation, anti-platelet aggregation and anti-oxidative activities. However, t know if flavonoids from rape bee pollen have the same effects in patients with dyslipidemia （DL）, effects of we don＇ type 2 diabetes mellitus（T2DM）, and cerebral infarction（CI）. Methods The study involved with patients selected and divided into 4 groups, 30 cases of DL, of T2DM, of CI and health control （HC） for each. Forty mg flavonoids from rape bee pollen administrated orally twice a day for two months. Blood sugar （BG）, total cholesterol （TC）, triglyceride （TG）, high density lipoprotein-cholesterol （HDL-C）, low white blood-cell counts （WBC）, platelet counts （PLT）, high-sens malondialdehyde （MDA） were analyzed in four groups before and after density lipoprotein-cholesterol （LDL-C）, itivity C-reactive protein （hsCRP） and taking flavonoids for two months. Results （1） Basic levels of TC, BG, WBC, PLT and hsCRP in groups of T2DM, CI, and TG and MDA in groups of DL, PLT, T2DM and CI were significantly higher than those in HC （P 〈 0.05-0.001）. （2） The levels of hsCRP and MDA were significantly decreased, flavonoids for two months （P 〈 0.05-0.001） in group of while HDL-C was remarkably increased DL, T2MD, and CL These indexes were not the group of HC after taking flavonoids （P 〉 0.05）. Conclusions The results could indieat disturbance, inflammation, and high oxidative stress in patients with dyslipidemisa, type 2 diabet TG, WBC, after taking different in e metabolic es mellitus, and cerebral infarction. The flavonoids from rape bee pollen may have effects of antioxidant activity, improving lipids, and anti-inflammation on these patients.展开更多
基金supported by The Capital Development Fund(2005-SF-Ⅱ-007)
文摘Background Flavonoids from fruits, vegetables and plants have been widely studied on their improving lipidemia, anti-inflammation, anti-platelet aggregation and anti-oxidative activities. However, t know if flavonoids from rape bee pollen have the same effects in patients with dyslipidemia （DL）, effects of we don＇ type 2 diabetes mellitus（T2DM）, and cerebral infarction（CI）. Methods The study involved with patients selected and divided into 4 groups, 30 cases of DL, of T2DM, of CI and health control （HC） for each. Forty mg flavonoids from rape bee pollen administrated orally twice a day for two months. Blood sugar （BG）, total cholesterol （TC）, triglyceride （TG）, high density lipoprotein-cholesterol （HDL-C）, low white blood-cell counts （WBC）, platelet counts （PLT）, high-sens malondialdehyde （MDA） were analyzed in four groups before and after density lipoprotein-cholesterol （LDL-C）, itivity C-reactive protein （hsCRP） and taking flavonoids for two months. Results （1） Basic levels of TC, BG, WBC, PLT and hsCRP in groups of T2DM, CI, and TG and MDA in groups of DL, PLT, T2DM and CI were significantly higher than those in HC （P 〈 0.05-0.001）. （2） The levels of hsCRP and MDA were significantly decreased, flavonoids for two months （P 〈 0.05-0.001） in group of while HDL-C was remarkably increased DL, T2MD, and CL These indexes were not the group of HC after taking flavonoids （P 〉 0.05）. Conclusions The results could indieat disturbance, inflammation, and high oxidative stress in patients with dyslipidemisa, type 2 diabet TG, WBC, after taking different in e metabolic es mellitus, and cerebral infarction. The flavonoids from rape bee pollen may have effects of antioxidant activity, improving lipids, and anti-inflammation on these patients.
