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Relationship between baseline monocyte to high-density lipoprotein cholesterol ratio and acute heart failure in postmenopausal women with acute coronary syndromes
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作者 WANG Ying ZHENG Hai-sheng +1 位作者 HUANG Zhen-chun ZHENG Xiao-dong 《South China Journal of Cardiology》 CAS 2021年第3期145-153,共9页
Monocyte to high-density lipoprotein cholesterol ratio(MHR)becomes a novel cardiovascular prognostic predictor.The retrospective study was performed to investigate the relationship between MHR and acute heart failure(... Monocyte to high-density lipoprotein cholesterol ratio(MHR)becomes a novel cardiovascular prognostic predictor.The retrospective study was performed to investigate the relationship between MHR and acute heart failure(AHF)in postmenopausal women with acute coronary syndromes(ACS).Methods A cohort of 127 postmenopausal women diagnosed with ACS were enrolled.They underwent coronary angiography in Shantou Central Hospital(Shantou,China)from December 2014 and July 2016.The patients were assigned to two groups based on the admission MHR:low MHR group(MHR≤0.3677,n=51)and high MHR group(MHR>0.3677,n=76).The relationship between MHR and AHF was assessed by logistic regression analysis.Results Left ventricular ejection fraction of the low MHR group(64.2%±8.8%)was higher than that of the high MHR group(57.6%±12.9%)(P=0.002).Fractional shortening of the low MHR group(35.4%±6.4%)was higher than that of the high MHR group(30.6%±8.9%)(P=0.001).Hospitalization days of high MHR group(11.4±6.6 days)was longer than that of low MHR group(8.4±3.5 days)(P=0.006).Incidence of AHF(21%)in the high MHR group was higher than that in the low MHR group(4%)(P=0.008).MHR(OR:25.701,95%CI:3.099-213.143,P=0.003)could be an independent predictor for AHF in postmenopausal women with acute coronary syndromes.Conclusions The incidence of AHF in high baseline MHR group was higher than that in low baseline MHR group.This study demonstrated that high MHR level was a risk factor for AHF in postmenopausal women with ACS. 展开更多
关键词 monocyte to high-density lipoprotein-cholesterol ratio acute heart failure postmenopausal women acute coronary syndromes
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ANALYSIS OF SERUM LIPIDS IN PSORIASIS
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作者 毛维翰 沈志鸿 陈铭生 《Medical Bulletin of Shanghai Jiaotong University》 CAS 1991年第1期99-103,共5页
Serum lipids were determined in 100 psoriatics and the results indicated (1) the incidences of hypercholesterolemia (9%) and hypertriglyceridemia (17%) in psoriatics were significantly higher than in controls; (2) the... Serum lipids were determined in 100 psoriatics and the results indicated (1) the incidences of hypercholesterolemia (9%) and hypertriglyceridemia (17%) in psoriatics were significantly higher than in controls; (2) the mean values of serum TC, LDL-C and TC/HDL-C in psoriatics were significantly higher as compared with normal healthy controls matched for sex and age; (3) serum TC, LDL-C and TG values were significantly higher in cases whose disease was progressive or whose lesions involved more than 20% of body surface area than in cases whose disease stationary or lesions less than 20%. As the incidences of hypertension and coronary heart disease were also significantly higher in psoriatics than in controls, the authors proposed that some integrated relationship would exist. 展开更多
关键词 PSORIASIS total serum CHOLESTEROL (TC) high-density lipoprotein-cholesterol (HDL-C) low-density lipoprotein-cholesterol (LDL-C) triglyceride (TG) HYPERCHOLESTEROLEMIA HYPERtriglycerideMIA
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Fatty acid desaturase 1 polymorphisms are associated with coronary heart disease in a Chinese population
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作者 LIU Si-jun ZHI Hong +9 位作者 CHEN Pei-zhan, CHEN Wei LU Feng MA Gen-shan DAI Jun-cheng SHEN Chong LIU Nai-feng HU Zhi-bin WANG Hui SHEN Hong-bing 《Chinese Medical Journal》 SCIE CAS CSCD 2012年第5期801-806,共6页
Background A recent genome-wide association study in Caucasians revealed that three loci (rs174547 in fatty acid desaturase 1 (FADS1), rs2338104 near mevalonate kinase/methylmalonic aciduria, cobalamin deficiency, ... Background A recent genome-wide association study in Caucasians revealed that three loci (rs174547 in fatty acid desaturase 1 (FADS1), rs2338104 near mevalonate kinase/methylmalonic aciduria, cobalamin deficiency, cblB type (MVK/MMAB) and rs10468017 near hepatic lipase (LIPC)) influence the plasma concentrations of high-density lipoprotein-cholesterol (HDL-C) and triglycerides (TG). However, there are few reports on the associations between these polymorphisms and plasma lipid concentrations in Chinese individuals. This study aimed to evaluate the associations between these three polymorphisms with HDL-C and TG concentrations, as well as coronary heart disease (CHD) susceptibility in Chinese individuals. 展开更多
关键词 high-density lipoprotein-cholesterol low-density lipoprotein-cholesterol triglyceride POLYMORPHISMS coronary heart disease fatty acid desaturase I
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