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Epidemiological Predicting of the Fleas on Rattus norvegicus
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作者 左小华 郭宪国 +2 位作者 詹银珠 吴滇 王乔花 《Agricultural Science & Technology》 CAS 2010年第4期116-117,143,共3页
[Objective]To predict prevalence of fleas via a simple epidemiological model.[Method]The field investigation was carried out in 23 locations in Yunnan Province.A simple epidemiological model was involved mean abundanc... [Objective]To predict prevalence of fleas via a simple epidemiological model.[Method]The field investigation was carried out in 23 locations in Yunnan Province.A simple epidemiological model was involved mean abundance and variance of abundance.[Result]The prevalence of fleas increased with their mean abundance in logistic curve.A linear correlation of the predicted prevalence against observed prevalence did not differ significantly from unity.[Conclusion]Prevalence could be explained simply by their mean abundance. 展开更多
关键词 FLEA ABUNDANCE PREVALENCE RODENT rattus norvegicus
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珠江三角洲黄毛鼠(Rattus rattoides exiguus)天敌食性的初步观察
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作者 李文笙 王英永 王磊 《生态科学》 CSCD 1990年第1期92-97,共6页
农田鼠害生物防治的可行性是人们非常关心的问题,也是鼠害综合防治的一个重要环节。本文着重从食性入手,观察研究了珠江三角洲黄毛鼠天敌滑鼠蛇的食性,以及其摄食量与温度、湿度的关系;并且还对黄毛鼠的另一类天敌(号鸟)类的食量情况作... 农田鼠害生物防治的可行性是人们非常关心的问题,也是鼠害综合防治的一个重要环节。本文着重从食性入手,观察研究了珠江三角洲黄毛鼠天敌滑鼠蛇的食性,以及其摄食量与温度、湿度的关系;并且还对黄毛鼠的另一类天敌(号鸟)类的食量情况作了初步观察。提出了对天敌在黄毛鼠生物防治的作用应采取一分为二的态度,一方面不宜过高估计其灭鼠作用,另一方面也应禁止捕捉鼠类天敌,保护其生活环境,维持生态平衡。 展开更多
关键词 黄毛鼠 滑鼠蛇 农田鼠害 rattus 摄食量 泽蛙 蛙类 过高估计 灭鼠 绝热式热量计
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Molecular Typing of Leptospira interrogans Strains Isolated from Rattus tanezumi in Guizhou Province,Southwest of China 被引量:13
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作者 LI Shi Jun ZHANG Cui Cai +6 位作者 LI Xiu Wen TIAN Ke Cheng TANG Guang Peng WANG Ding Ming LIU Ying NIE Yi Xin JIANG Xiu Gao 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第5期542-548,共7页
Abstract Objective To identify and type three leptospires isolated from Rattus tanezumi in Guizhou Province by using three molecular techniques (PFGE, MLVA, and MLST), reveal the molecular characteristic of causativ... Abstract Objective To identify and type three leptospires isolated from Rattus tanezumi in Guizhou Province by using three molecular techniques (PFGE, MLVA, and MLST), reveal the molecular characteristic of causative agents of local leptospirosis and evaluate these three molecular methods based on their detection resolution and efficiency. Methods Three Leptospira strains were isolated from the kidney of Rattus tanezumi and cultured with EMJH medium. PFGE, MLVA, and MLST assays were applied to type the three strains isolated from Rattus tanezumi in Guizhou Province. Results PFGE, MLVA, and MLST typing showed that the three leptospiral isolates matched with leptospiral serogroup Icterohaemorrhagiae serovar Lai. The findings of the genotyping methods were consistent. MLVA and MLST defined genotypes, whereas PFGE allowed the recognition of additional subgroups within the genotypes, and the findings of molecular typing were also consistent with those of traditional techniques. Conclusion Three leptospiral isolates from Guizhou Province matched with leptospiral serogroup Icterohaemorrhagiae serovar Lai, and PFGE, MLVA, and MLST, as reliable molecular techniques for identifying and typing of Leptospira interrogans, would contribute to the active surveillance, outbreak investigation and source tracking for leptospirosis in Guizhou Province. 展开更多
关键词 L. interrogans PFGE MLVA MLST rattus tanezumi
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How many species of Apodemus and Rattus occur in China? A survey based on mitochondrial cyt b and morphological analyses 被引量:9
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作者 Shao-Ying Liu Kai He +5 位作者 Shun-De Chen Wei Jin Robert W.Murphy Ming-Kun Tang Rui Liao Feng-Jun Li 《Zoological Research》 SCIE CAS CSCD 2018年第5期309-320,共12页
Apodemus (mice) and Rattus (rats) are the top rodent reservoirs for zoonoses in China,yet little is known about their diversity.We reexamined the alpha diversity of these two genera based on a new collection of sp... Apodemus (mice) and Rattus (rats) are the top rodent reservoirs for zoonoses in China,yet little is known about their diversity.We reexamined the alpha diversity of these two genera based on a new collection of specimens from China and their cyt b sequences in GenBank.We also tested whether species could be identified using external and craniodental measurements exclusively.Measurements from 147 specimens of Apodemus and 233 specimens of Rattus were used for morphological comparisons.We analysed 74 cyt b sequences of Apodemus and 100 cyt b sequences of Rattus to facilitate phylogenetic estimations.Results demonstrated that nine species of Apodemus and seven species of Rattus,plus a new subspecies of Rattus nitidus,are distributed in China.Principal component analysis using external and craniodental measurements revealed that measurements alone could not separate the recognized species.The occurrence of Rattus pyctoris in China remains uncertain. 展开更多
关键词 Alpha diversity APODEMUS DNA-barcoding rattus Taxonomy PHYLOGENIES New subspecies
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Sequence Divergence of Mitochondrial 12S rRNA Gene and Phylogenetic Relationship Between Rattus rattus Sladeni and Rattus rattus Hainanicus
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作者 JIANGQing-lan HeMiao +2 位作者 XINJing-xi OOIE.C.Vincent KWANHoi-shan 《中山大学学报(自然科学版)》 CAS CSCD 北大核心 2005年第3期82-85,共4页
The appearance and hair color between these two subspecies Rattus rattus Sladeni and R.r. Hainanicus are similar to each other. Their most major distinctive characteristic is the length ratio of tail to body. However,... The appearance and hair color between these two subspecies Rattus rattus Sladeni and R.r. Hainanicus are similar to each other. Their most major distinctive characteristic is the length ratio of tail to body. However, this characteristic was unstable in some measuring records. In Guangdong, R.r. Hainanicus is restrictedly distributed in the west region, and R.r. Sladeni is widely distributed in the other regions of this province. In this study, we detected the sequences of mitochondrial 12S rRNA gene fragments of 9 samples from R.r. Hainanicus and R.r. Sladeni (Longmen and Hong Kong populations). These 385 nucleotide positions of 12S rRNA gene fragment include 26 variable sites and 14 parsimony-informative sites. 3 insertion/deletion sites are observed. The phylogenetic relationships among these samples were constructed by Neighbor-joining and Maximum parsimony methods. The analysis shows that R.r. Hainanicus is more closely relative to the Longmen population of R.r. Sladeni than to the Hong Kong population of R.r. Sladeni. The sequencing analysis of 12S rRNA gene fragments is not agreement on the classification of subspecies R. r. Hainanicus inferred from the morphology and geographical distribution. The morphological variation of R.r. Hainanicus should result from the natural selection, which causes local adaptation and geographic isolation. 展开更多
关键词 rattus rattus Sladeni R.r. Hainannicus MITOCHONDRIAL DNA sequence DIVERGENCE PHYLOGENETIC RELATIONSHIPS
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Isolation of Kytococcus schroeteri from the brown rat Rattus norvegicus
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作者 Shih Keng Loong Nurul Asma Anati Che-Mat-Seri +4 位作者 Kim-Kee Tan Noor-Syahida Azizan Siti Noraisah Ahmad-Nasrah Siti Nursheena Mohd-Zain Sazaly AbuBakar 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2021年第4期191-192,共2页
Rodents such as Rattus rattus and Rattus norvegicus have adapted to living close to human settlements[1].This presents a public health challenge as these rodents are considered as pests that can transmit a number of z... Rodents such as Rattus rattus and Rattus norvegicus have adapted to living close to human settlements[1].This presents a public health challenge as these rodents are considered as pests that can transmit a number of zoonotic diseases to humans[1,2].A rodent surveillance programme was initiated between the years 2014 and 2015,focusing on rodents captured at wet markets where there is abundant food and considerable human traffic.The present study was conducted in several wet markets in Kuala Terengganu,Malaysia(5.3333°N,103.1500°E). 展开更多
关键词 rattus initiated abundant
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RNA Interference-Mediated Downregulation of sAC Gene Inhibits Sperm Hyperactivation in Male Rats(Rattus norvegicus)
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作者 YU Jing JIANG Xiao-qiang +1 位作者 ZHOU Shuai WANG Gen-lin 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2014年第2期394-401,共8页
Hyperactivation is one of the most critical parts for fertilization, cAMP generated by soluble adenylyl cyclase (sAC) is necessary to activate sperm and is a prerequisite for sperm hyperactivation. The aim of this s... Hyperactivation is one of the most critical parts for fertilization, cAMP generated by soluble adenylyl cyclase (sAC) is necessary to activate sperm and is a prerequisite for sperm hyperactivation. The aim of this study is to investigate the function of sAC in hyperactivation in male rats. Four siRNAs of sAC gene were designed and separately transformed into rat sperm using electrotransformation method. Cultured for 12 and 24 h, physiological and biochemical indexes of these sperm were analyzed, and the expressions of some hyperactivation-related genes were detected using real-time PCR. We demonstrated 26.3-30.8% and 49.1-50.5% reduction in sAC at the protein by Western blot and mRNA levels by real-time PCR, respectively. The results showed that two siRNAs, Actb-717 and Actb-4205, were the best RNAi sites for silencing sAC. The VCL (curvilinear velocity) and ALH (amplitude of lateral head displacement) of RNA interference (RNAi)-transfected sperm were reduced, cAMP and protein phosphorylation in RNAi transfected sperm were also decreased. The hyperactivation-related genes, such as CatSper2, LDHC and PKA, were downregulated in the sperm, which sAC was knockdown. These findings demonstrated that sAC might play a critical role in cAMP signaling in the rat sperm hyperactivation, and downregulated sAC gene might prevent the expression of these hyperactivation-ralated genes resulting in sperm dysfunction. These findings suggest that these hyperactivation-ralated genes and sAC are functionally related in sperm hyperactivation and sAC falls into an expanding group of sperm proteins that appear to be promising targets for the development of male contraceptives. 展开更多
关键词 rattus norvegicus HYPERACTIVATION SAC RNAi male contraceptives
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大鼠在医学实验中的应用
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作者 杜力军 张庆文 《陕西中医学院学报》 1991年第4期47-47,共1页
现在所用的大鼠,几乎全部来自挪威种(Rattus Norvegicus)。一般认为这种大鼠最早生活于西伯利亚的贝加尔湖,以及东欧的里海和特伯尔斯克(Tocolsk)之间的地带。18世纪,随着贸易发展该鼠传播至整个欧洲和美国。19世纪中叶,该种鼠广泛用于... 现在所用的大鼠,几乎全部来自挪威种(Rattus Norvegicus)。一般认为这种大鼠最早生活于西伯利亚的贝加尔湖,以及东欧的里海和特伯尔斯克(Tocolsk)之间的地带。18世纪,随着贸易发展该鼠传播至整个欧洲和美国。19世纪中叶,该种鼠广泛用于解剖学、生理学及营养学等方面的研究。20世纪初,H·H Donaldson等培育了第一代近交系大鼠,并由其同事用于遗传学和癌症的研究。目前大鼠常用于如下几方面研究。 1、在器官移植方面当今实验性移植研究主要从四个方面进行。即:小肠、心脏和肝脏的同种动物间移植;神经组织移植,异种动物间皮肤移植;生殖研究等。这些方面,大鼠是主要的实验对象。 展开更多
关键词 大鼠 医学实验 器官移植 近交系 组织移植 小肠移植 皮肤移植 伯尔 移植研究 rattus
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珠江三角洲主要害鼠染色体分类的研究
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作者 江庆澜 《生态科学》 CSCD 1990年第1期116-128,共13页
本文对珠江三角洲主要害鼠的5个种以及种内有明显变异的群体的染色体组型进行研究,从染色体组型的角度探讨这些动物的分类地位。在本项研究的3个属的动物中,Y染色体均为末端着丝粒染色体,说明这些动物的Y染色体具有同源性,是科内动物的... 本文对珠江三角洲主要害鼠的5个种以及种内有明显变异的群体的染色体组型进行研究,从染色体组型的角度探讨这些动物的分类地位。在本项研究的3个属的动物中,Y染色体均为末端着丝粒染色体,说明这些动物的Y染色体具有同源性,是科内动物的共同特征。 Mus和Bandicota两个属中2n、NF和常、X染色体形态都具有明显的区别,基本证实了目前主要根据形态学所确定的这两个属的分类系统。但Rattus属中各种动物的NF及X染色体形态有差异。小家鼠与小田鼠的核型分析结果表明,它们更可能是不同的亚种。黑型褐家型与褐型褐家鼠的核型有明显差异,很可能分化为不同的种。黄毛鼠与褐家鼠(褐型)的核型相同,值得进一步研究。 展开更多
关键词 害鼠 染色体形态 染色体组型 rattus 端着丝粒染色体 核型分析结果 黄毛鼠 黄腹鼠 黄胸鼠 板齿鼠
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大鼠UQCRFS1基因的克隆及其表达模式分析 被引量:1
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作者 张婷 黄青松 范雪晖 《湖北农业科学》 北大核心 2013年第9期2174-2177,共4页
通过克隆获得泛醌-细胞色素C还原酶铁硫蛋白亚基1(Ubiquinol-cytochrome C reductase iron-sulfur subunit 1,UQCRFS1)基因,对基因序列及其编码的蛋白质进行分析,研究了其在大鼠(Rattusnorvegicus)心、脑、肾、肺组织中的表达模式。测... 通过克隆获得泛醌-细胞色素C还原酶铁硫蛋白亚基1(Ubiquinol-cytochrome C reductase iron-sulfur subunit 1,UQCRFS1)基因,对基因序列及其编码的蛋白质进行分析,研究了其在大鼠(Rattusnorvegicus)心、脑、肾、肺组织中的表达模式。测序结果显示UQCRFS1基因全长826 bp,RT-PCR结果显示其在大鼠心脏中表达量较高,脑和肺中表达量稍低,肾脏组织中表达量最低,推测UQCRFS1的功能可能与大鼠的心脏发育有关。 展开更多
关键词 大鼠(rattus norvegicus) UQCRFS1基因 克隆 表达模式
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Survey of Angiostrongylus cantonensis in rats and giant African land snails in Phitsanulok province,Thailand 被引量:1
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作者 Apichat Vitta Raxsina polseela +1 位作者 Seangchai Nateeworanart Muncharee Tattiyapong 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2011年第8期597-599,共3页
Objective:To survey the Angiostrongylus cantonensis(A.cantonensis) or the rat lungworm in a rat,definitive host,and in a giant African land snail(Achatina fulica),the intermediate host,in Phitsanulok,Thailand.Methods:... Objective:To survey the Angiostrongylus cantonensis(A.cantonensis) or the rat lungworm in a rat,definitive host,and in a giant African land snail(Achatina fulica),the intermediate host,in Phitsanulok,Thailand.Methods:Rats and giant African land snails were captured from Tha Pho sub-district,Phitsanulok,Thailand.Rats were killed and examined for adult A.cantonensis. The artificial digestion method following Baermann technique were used for isolation third stage larvae of A.cantonensis.Results:Sixty-two rats were captured and they were identified as Rattus argentiventer,Rattus rattus(R.rattus),Bandicota savilei,and Bandicota indica but only one animal(R.rattus) of 62 rats(1.61%) was positive with adult worm of A.cantonensis.The third stage larvae of A.cantonensis were examined on 307 Angiostrongylus fulica snails.It was found that the overall infection rate was 12.38%(38 infected out of 307 Achatina snails).Conclusions: This study demonstrates that A.cantonensis is available in the natural hosts of Phitsanulok.This suggests that the transmissions of this parasite to human may occur in this region. 展开更多
关键词 ANGIOSTRONGYLUS cantonensis rattus rattus Achatina fulica
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褐家鼠与大仓鼠消化系统比较
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作者 于成文 徐春雨 +1 位作者 李博琦 金志民 《湖北农业科学》 2019年第24期175-176,179,共3页
为了解褐家鼠(Rattus norvegicus)与大仓鼠(Cricetulus triton)消化系统之间的差异,试验对两种鼠进行解剖。结果表明,褐家鼠食管平均长度占体长比值是大仓鼠的0.873倍;胃(不含内容物)的平均质量占体重比值是大仓鼠的0.462倍;小肠平均长... 为了解褐家鼠(Rattus norvegicus)与大仓鼠(Cricetulus triton)消化系统之间的差异,试验对两种鼠进行解剖。结果表明,褐家鼠食管平均长度占体长比值是大仓鼠的0.873倍;胃(不含内容物)的平均质量占体重比值是大仓鼠的0.462倍;小肠平均长度占体长的比值是大仓鼠的1.557倍,大肠平均长度占体长比值是大仓鼠的0.383倍,盲肠平均长度占体长比值是大仓鼠的0.283倍;肝重与体重比值是大仓鼠的1.190倍。两种鼠的消化系统中器官长度和结构有多处差异,两种鼠对于食物质量选择的分化程度明显,且褐家鼠食物选择广泛,大仓鼠对植物性食物依赖性更高。 展开更多
关键词 褐家鼠(rattus norvegicus) 大仓鼠(Cricetulus triton) 消化系统 比较
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Biochemical and histopathological profiling of Wistar rat treated with Brassica napus as a supplementary feed 被引量:1
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作者 Kazi Md.Mahmudul Hasan Nasrin Tamanna MdAnwarul Haque 《Food Science and Human Wellness》 SCIE 2018年第1期77-82,共6页
Metabolic changes together with cardiovascular and hepatic factors are related to the development of diseases like myocardial lipidosis,heart disease,and profound toxicity.The aim of this animal study is to determine ... Metabolic changes together with cardiovascular and hepatic factors are related to the development of diseases like myocardial lipidosis,heart disease,and profound toxicity.The aim of this animal study is to determine the effects of high erucic acid containing rapeseed oil(Brassica napus L.)varieties on liver,kidney and heart muscles in Wistar rats.Male Wistar rats were divided into three groups where each group containing four rats.Group A was considered as control diet group,while Group B rapeseed wild oil group and Group C rapeseed hybrid oil group were considered as experimental diet groups.The levels of aspartate aminotransferase(AST),alanine aminotransferase(ALT),alkaline phosphatase(ALP),creatine kinase-MB(CK-MB)and creatinine of two experimental groups were significantly elevated while compared to the control groups(p<0.05–0.001).Nevertheless,an increment in weight retardation(p<0.05)was also observed in rapeseed hybrid oil treated groups.No significant weight retardation found in other two groups(p>0.05).Noticeable tissue injury observed in this study is a sign of the relative toxicity of erucic acid containing rapeseed oil to mammalian species.The use of Brassica napus as a supplementary feed ingredient should be,therefore,thoroughly considered. 展开更多
关键词 Rapeseed oil rattus norvegicus Serum enzymes Erucic acid Tissue profiling
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The antioxidative effects of some medicinal plants as hypoglycemic agents on chromosomal aberration and abnormal nucleic acids metabolism produced by diabetes stress in male adult albino rats 被引量:1
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作者 Sherifa H. Salah Halima S. Abdou +1 位作者 Amal S. Abd El Azeem E.A. Abdel-Rahim 《Journal of Diabetes Mellitus》 2011年第1期6-14,共9页
The objectives of the present study are to evaluate the chromosomal aberrations in somatic and germ cells of alloxanized diabetic rats treated with methanolic extracts of Cleome droserifolia (Sammo), Anastatica hieroc... The objectives of the present study are to evaluate the chromosomal aberrations in somatic and germ cells of alloxanized diabetic rats treated with methanolic extracts of Cleome droserifolia (Sammo), Anastatica hierochuntica (Kafta), Juniperus phoencea (Araar) and Hyphaene thebaica (Doum) as well as their effects on blood glucose, liver and testes total soluble protein, DNA and RNA contents and also nucleases (RNAase and DNAase) activity. The material and Methods: The study was performed in six groups. The first group was the normal healthy control;the second group was rats injected with alloxan (diabetic control). Every one of the other four groups (diabetic rats) was ingested with each of the methanolic extracts of Kafta, Doum, Sammo and Araar (individually). The results: The results of chromosomal analysis showed that, diabetic rats had a highly significant increase of chromosomal aberrations compared to that of normal healthy control. Animals which treated with the four plants methanolic extracts showed significant improvements in the frequencies of chromosomal aberrations. In case of biochemical analysis, blood glucose level was significantly increased but immunoglobulins levels were decreased in diabetic albino rats. Diabetes increased serum total lipids, cholesterol, triglycerides and LDL but serum HDL was decreased. RNA and DNA as well as inhibited the nucleases (RNAase and DNAase) activity of both organs (liver and testes) tissue. The conclusions: It is concluded that diabetes is much harmful in the animal body, whilst the induction of flavonoids extract (by methanol) of Kafta, Somma, Araar and Doum reduced these harmful of diabetes. 展开更多
关键词 Alloxan: Recrystallized Methanolic EXTRACTS of Anastatica Hierochuntica (Kafta) Hyphaene Thebaica (Doum) CLEOME Droserfolia (Sammo) JUNIPERUS Phoenicea (Araar) and rattus Norvegicus
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Reproductive ecology of the black rat (Rattus rattus) in Madagascar: the influence of density-dependent and -independent effects 被引量:1
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作者 Kathryn SCOBIE Soanandrasana RAHELINIRINA +7 位作者 Voahangy SOARIMALALA Fehivola Mandanirina ANDRIAMIARIMANANA Corinne RAHAINGOSOAMAMITIANA Toky RANDRIAMORIA Soloandry RAHAJANDRAIBE Xavier LAMBIN Minoarisoa RAJERISON Sandra TELFER 《Integrative Zoology》 SCIE CSCD 2024年第1期66-86,共21页
The black rat(Rattus rattus)poses a severe threat to food security and public health in Madagascar,where it is a major cause of pre-and post-harvest crop losses and an important reservoir for many zoonotic diseases,in... The black rat(Rattus rattus)poses a severe threat to food security and public health in Madagascar,where it is a major cause of pre-and post-harvest crop losses and an important reservoir for many zoonotic diseases,including plague.Elsewhere,ecologically based rodent management(EBRM)strategies have been developed using ecologi-cal information to inform decisions on where and when to target control.EBRM could deliver improved health and well-being outcomes in Madagascar if adapted to the local ecological context.Using data collected from removal studies,we explored spatio-temporal patterns in the breeding activity of the black rat(R.rattus)in domestic and agricultural habitats across Madagascar and investigated to what extent these trends are influenced by rainfall and rat density.We identified clear spatio-temporal variation in the seasonality of R.rattus reproduction.Reproduction was highly seasonal both inside and outside of houses,but seasonal trends varied between these two habitats.Sea-sonal trends were explained,in part,by variation in rainfall;however,the effect of rainfall on reproductive rates did itself vary by season and habitat type.A decline in breeding intensity with increasing rat density was recorded outside of houses.This has important implications for control,as populations may compensate for removal through increased reproduction.We recommend that sustained control initiated before the main breeding season,combined with improved hygiene and adequate rodent-proofing in homes and grain stores,could curtail population growth and reduce pre-and post-harvest losses provided that these measures overcome the compensatory response of rodent populations. 展开更多
关键词 Madagascar rattus rattus reproductive ecology rodent control
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First histopathological study in kidneys of rodents naturally infected with Leptospira pathogenic species from Yucatan, Mexico
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作者 Marco Torres-Castro Leonardo Guillermo-Cordero +5 位作者 Silvia Hernández-Betancourt Edwin Gutiérrez-Ruíz Piedad Agudelo-Flórez Ronald Peláez-Sánchez Jorge Zavala-Castro Fernando I.Puerto 《Asian Pacific Journal of Tropical Medicine》 SCIE CAS 2016年第2期140-142,共3页
Objective: To report the renal histological lesions in synanthropic rodents, Mus musculus and Rattus rattus, naturally infected with Leptospira spp., captured in a rural community in Yucatan, Mexico. Methods: Kidney s... Objective: To report the renal histological lesions in synanthropic rodents, Mus musculus and Rattus rattus, naturally infected with Leptospira spp., captured in a rural community in Yucatan, Mexico. Methods: Kidney samples of synanthropic rodents were collected from a rural community in Yucatan, Mexico. Polymerase chain reaction was used to detect Leptospira spp. infection. Tissue kidney was fixed in 10% buffered formalin, processed according to the usual techniques for paraffin inclusion, cut and stained with hematoxylin and eosin, and examined using a conventional electronic microscope. Results: A total of 187 rodents were captured. Nine individuals(4.8%) were positive for Leptospira spp. in the molecular analysis. All renal lesions observed in the histopathological study had been reported previously for Leptospira spp. infection. Conclusions: The histopathological lesions are present in the kidneys, plus the results of the polymerase chain reaction confirm that these rodents are true carriers of Leptospira spp. 展开更多
关键词 LEPTOSPIRA spp. Renal histopathological lesions MUS musculus rattus rattus
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Antifertility effects of EP-1 (quinestrol and levonorgestrel) on Pacific rats (Rattus exulans) 被引量:1
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作者 Jing LIU Feiyun TU +2 位作者 Ming LIU Jichao WANG Zhibin ZHANG 《Integrative Zoology》 SCIE CSCD 2024年第1期127-142,共16页
Pest rodents pose a serious threat to island biodiversity.Fertility control could be an alternative approach to control the impact of rodents on these islands.In this study,we examined the antifertility effects of EP-... Pest rodents pose a serious threat to island biodiversity.Fertility control could be an alternative approach to control the impact of rodents on these islands.In this study,we examined the antifertility effects of EP-1 baits containing quinestrol(E)and levonorgestrel(P)using a dose of 50 ppm E and P at three different ratios(E:P ratio=1:2,1:1,and 2:1)on Pacific rats(Rattus exulans)in the Xisha Islands,Hainan,China.Compared to the control group,all animals in EP-1 treatment groups showed significantly decreased food intake and body weight.In treated males,there were obvious abnormalities in testis structure and a significant decrease of relative seminal vesicle weight,but no significant effect on relative uterine and ovarian weights(g kg-1 body weight),or ovarian structure in females.Adding 8%sucrose to the original 50-ppm baits(E:P ratio=1:1)significantly increased bait palatability for males and females.This dose induced uterine edema and abnormalities of ovarian structure in females but had no significant negative effect on the relative testis,epididymis,and seminal vesicle weights(g kg-1 body weight)or sperm density in males.In summary,50-ppm EP-1(1:1)baits have the potential to disrupt the fertility of females,and 8%sucrose addition to the EP-1 baits(E:P ratio=1:1)could improve bait palatability.This dose disrupted the testis structure in males.Future studies are needed to improve bait acceptance and assess the antifertility effects of EP-1(1:1)on Pacific rats in captive breeding trials and underfield conditions. 展开更多
关键词 EP-1 fertility control island biodiversity conservation LEVONORGESTREL QUINESTROL rattus exulans
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Reversible antispermatogenic and antisteroidogenic activities of Feronia limonia fruit pulp in adult male rats
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作者 Ramaiyan Dhanapal J.Vijaya Ratna +1 位作者 I.Sarathchandran Malaya Gupta 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2012年第9期684-690,共7页
Objective:To explore the antispermatogenic and testicular antisleroidogenic activities of Feronia limonia fruit pulp southern India.Methods:Fourty Wistar male albino rats(Ratios norvegicus)were equally divided into fo... Objective:To explore the antispermatogenic and testicular antisleroidogenic activities of Feronia limonia fruit pulp southern India.Methods:Fourty Wistar male albino rats(Ratios norvegicus)were equally divided into four groups.Experimental groups were administered with the ethanolic extract of Feronia lirnonia(F.limoni)fruit pulp at doses of 250 and 500 nig/kg body weight once daily for 55 days.All treated rats had corresponding recovery groups.At the end of each treatment periods,various spermatological indices,tissue biochemicals and testicular enzymes levels were analysed.Blood profiles were also estimated.Results:Compared with the control,the F.lirnonia.fruit pulp at both dose leveb did not decrease body weight,which were associated with decline in epididymal sperm count,motility,viability and increased percent of abnormal sperm.Further,F.limonia.fruit pulp at 500 mg/kg body weight markedly reduced the epididymal and testicular protein content by 24.58%and 29.86%,respectively,as well as the glucose-6-phosphate dehydrogenase and△~5-3β-hydroxy steroid dehydrogenase)levels by 42.82%and 38.08%,respectively,while a significant elevation was observed in testicular cholesterol and ascorbic acid content.A gradual recovery of all parameters was observed after 55 days of treatment withdrawal.No significant alterations in haematological indices were observed.Conclusions:The present findings indicate that F.lirnonia fruit pulp may have reversible antispermatogenic and antisteroidogenic properties,and could partially support the traditional use as mate contraceptive. 展开更多
关键词 Feronia limonia Antispermatogenic TESTICULAR antisteroidogenic rattus norvegicus HEMATOLOGICAL indices
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A comparative analysis of differentially expressed genes in rostral and caudal regions after spinal cord injury in rats
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作者 Xue-Min Cao Sheng-Long Li +4 位作者 Yu-Qi Cao Ye-Hua Lv Ya-Xian Wang Bin Yu Chun Yao 《Neural Regeneration Research》 SCIE CAS CSCD 2022年第10期2267-2271,共5页
The initial mechanical damage of a spinal cord injury(SCI)triggers a progressive secondary injury cascade,which is a complicated process integrating multiple systems and cells.It is crucial to explore the molecular an... The initial mechanical damage of a spinal cord injury(SCI)triggers a progressive secondary injury cascade,which is a complicated process integrating multiple systems and cells.It is crucial to explore the molecular and biological process alterations that occur after SCI for therapy development.The differences between the rostral and caudal regions around an SCI lesion have received little attention.Here,we analyzed the differentially expressed genes between rostral and caudal sites after injury to determine the biological processes in these two segments after SCI.We identified a set of differentially expressed genes,including Col3a1,Col1a1,Dcn,Fn1,Kcnk3,and Nrg1,between rostral and caudal regions at different time points following SCI.Functional enrichment analysis indicated that these genes were involved in response to mechanical stimulus,blood vessel development,and brain development.We then chose Col3a1,Col1a1,Dcn,Fn1,Kcnk3,and Nrg1 for quantitative real-time PCR and Fn1 for immunostaining validation.Our results indicate alterations in different biological events enriched in the rostral and caudal lesion areas,providing new insights into the pathology of SCI. 展开更多
关键词 biological process CAUDAL differentially expressed genes Gene Ontology HEMISECTION IMMUNOSTAINING rattus norvegicus RNA-sequencing rostral spinal cord injury
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昆明动物所揭示高原鼢鼠高海拔洞穴适应遗传机制
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作者 邵永为 张亚平 《江西饲料》 2015年第6期46-47,共2页
高原鼢鼠(Myospalax baileyi)是青藏高原的土著啮齿类物种之一,它们普遍栖息于地下约1.5~2米深的密闭洞穴中。经过长期的自然选择,高原鼢鼠已经对青藏高原这种特殊环境(高海拔洞穴缺氧)表现出极强的适应性。例如:其血液中红细胞... 高原鼢鼠(Myospalax baileyi)是青藏高原的土著啮齿类物种之一,它们普遍栖息于地下约1.5~2米深的密闭洞穴中。经过长期的自然选择,高原鼢鼠已经对青藏高原这种特殊环境(高海拔洞穴缺氧)表现出极强的适应性。例如:其血液中红细胞数目以及血红蛋白含量明显多于同域生存的其它物种(例如:鼠兔(Ochotona curzniae)和大鼠(Rattus norvegicus))、动脉血的氧分压约是同域生存的鼠兔和大鼠的1.5倍以及高效的肺气扩散能力等等。这些生理现象暗示了高原鼢鼠拥有强的从低氧一高碳酸环境中获取氧气的能力。然而,目前对高原鼢鼠的高原适应性进化遗传机制研究甚少。 展开更多
关键词 高原鼢鼠 血红蛋白含量 细胞数目 大鼠 OCHOTONA rattus 比较基因组学 遗传机制 适应性进化 基因组水平
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