Read-Write Dependency Aware Register Allocation

Read-write dependency is an important factor restricting software efficiency.Timing Speculative(TS)is a processing architecture aiming to improve energy efficiency of microprocessors.Timing error rate,influenced by the read-write dependency,bottlenecks the voltage down-scaling and so the energy efficiency of TS processors.We proposed a method called Read-Write Dependency Aware Register Allocation.It is based on the Read-Write Dependency aware Interference Graph(RWDIG)conception.Registers are reallocated to loosen the read-write dependencies,so resulting in a reduction of timing errors.The traditional no operation(Nop)padding method is also redesigned to increase the distance value to above 2.We analyzed the dependencies of registers and maximized the average distance value of read and write dependencies.Experimental results showed that we can reduce all read-write dependency by Nop padding,as well as the overhead timing errors.An energy saving of approximately 7%was achieved.

Dissipative soliton resonance within different dispersion regimes in a single mode-locked laser

Dissipative soliton resonance(DSR) was previously studied in separated mode-locked fiber lasers within different dispersion regimes including anomalous, near-zero and normal dispersion. Here we propose a method to study DSR in a single mode-locked laser in these different dispersion regimes. This is achieved by virtue of a waveshaper which can control the laser dispersion readily using software, avoiding the usual tedious cutback method. We find that dispersion has a negligible effect on DSR since the pulse duration keeps constant while dispersion is varied. Moreover, we examine the dynamics of DSR on the parameters of the SA including modulation depth and saturation power, and find that the pulse duration can be changed in a large range when the saturation power is decreased. Our numerical simulations could be important to guide relative experimental studies.

On the generation of high-quality Nyquist pulses in mode-locked fiber lasers

Nyquist pulses have wide applications in many areas,from electronics to optics.Mode-locked lasers are ideal platforms to generate such pulses.However,how to generate high-quality Nyquist pulses in mode-locked lasers remains elusive.We address this problem by managing different physical effects in mode-locked fiber lasers through extensive numerical simulations.We find that net dispersion,linear loss,gain and filter shaping can affect the quality of Nyquist pulses significantly.We also demonstrate that Nyquist pulses experience similariton shaping due to the nonlinear attractor effect in the gain medium.Our work may contribute to the design of Nyquist pulse sources and enrich the understanding of pulse shaping dynamics in mode-locked lasers.

Phase-locked single-mode terahertz quantum cascade lasers array

We demonstrated a scheme of phase-locked terahertz quantum cascade lasers(THz QCLs)array,with a single-mode pulse power of 108 mW at 13 K.The device utilizes a Talbot cavity to achieve phase locking among five ridge lasers with first-order buried distributed feedback(DFB)grating,resulting in nearly five times amplification of the single-mode power.Due to the optimum length of Talbot cavity depends on wavelength,the combination of Talbot cavity with the DFB grating leads to better power amplification than the combination with multimode Fabry-Perot(F-P)cavities.The Talbot cavity facet reflects light back to the ridge array direction and achieves self-imaging in the array,enabling phase-locked operation of ridges.We set the spacing between adjacent elements to be 220μm,much larger than the free-space wavelength,ensuring the operation of the fundamental supermode throughout the laser's dynamic range and obtaining a high-brightness far-field distribution.This scheme provides a new approach for enhancing the single-mode power of THz QCLs.

A novel dual-channel thermo-optic locking method for the whispering gallery mode microresonator

Mode locking can be effectively achieved by using the thermo-optic effects in the whispering gallery mode(WGM)optical microcavity,without the help of external equipment.Therefore,it has the advantages of small size,low integration costs,and self-locking,which shows great potential for application.However,the conventional single-channel microcavity thermal-locking method that relies solely on internal thermal balance will inevitably be disturbed by the external environment.This limitation affects the locking time and stability.Therefore,in this paper,we propose a new method for closed-loop thermal locking of a dual-channel microcavity.The thermal locking of the signal laser and the thermal regulation of the control laser are carried out respectively by synchronously drawing a dual-path tapered fiber.The theoretical model of the thermal dynamics of the dual-channel microcavity system is established,and the influence of the control-laser power on the thermal locking of the signal laser is confirmed.The deviation between the locking voltage of the signal laser and the set point value is used as a closed-loop feedback parameter to achieve long-term and highly stable mode locking of the signal laser.The results show that in the 2.63 h thermal-locking test,the locking stability is an order of magnitude higher than that of the single tapered fiber.This solution addresses the issue of thermal locking being disrupted by the external environment,and offers new possibilities for important applications such as spectroscopy and micro-optical sensor devices.

Early Treatment Outcome of Humeral Shaft Fracture Non-Union in Adults: Comparative Study of Plating versus Interlocking Nailing

Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is a major problem in this part of the world. This non-union is a major treatment challenge with increased cost of care and morbidity in this part of the world. Humeral shaft non-union can be treated with locked intra-medullary nailing (LIMN) or dynamic compression plating (DCP). Study on comparison of these methods of fixation in this part of the world is scarce in literature search, hence the reason for this study. Objective: The objectives of this study are: (1) to compare early clinical outcome following fixation of humeral shaft fracture nonunion with DCP versus LIMN;(2) to compare the time of radiologic fracture union of DCP with LIMN;(3) to compare complications following fixation of humeral shaft fracture nonunion with DCP versus LIMN. Patients and Methods: This was a randomized control study done for 2 years in which fifty adult patients with humeral shaft non-union were recruited. The patients were grouped into 2 (P = DCP & N = LIMN). Forty five of the patients completed the follow up periods of the study and then analyzed. The P group had ORIF with DCP while the N group had ORIF with LIMN. Both groups had grafting with cancellous bones. Each patient was followed up for a period of 6 months at the time which radiographic union is expected. Any patient without clinical and/or radiographic evidence of union after six months of surgery was diagnosed as having recurrent non-union. The data generated was analyzed using SPSS Version 23. The results were presented in charts and tables. The paired t-test was used while considering p value Result: Forty five patients completed follow up. There was a male preponderance (4:1), right humerus predominated (3:2). Motor vehicular accidents were the commonest cause of the fractures (62%). Most non-union fractures occurred at the level of the middle 3rd of the humeral shaft (60%). Failed TBS treatment was the commonest indication for the osteosynthesis (71%). More patients had plating (53%) compared to 47% who had LIMN. Most patients (93.4%) had union between 3 to 6 months irrespective of fixation type with no significant statistical difference between the union rate of DCP and LIMN (p value 0.06) with similar functional outcome and complication rates irrespective of the type of fixation. Conclusion: This study showed that the success rates in term of fracture union, outcome functional grades and complication rates were not directly dependent on the types of the fixation: plating or locked intra-medullary nailing.

Unlocking Cellular Mysteries:Advancements in Single-Cell Omics Analysis with Genome-Scale Metabolic Modeling

The widespread applications of single-cell technologies have generated a large amount of single-cell data,resulting in a growing need for single-cell data analysis and interpretation methods.While methods such as machine learning allow for single-cell data analysis,they cannot interpret the data very well.

Fast-Lock Low-Jitter PLL with a Simple Phase-Frequency Detector

A fast-locking, low-jitter, phase-locked loop （PLL） with a simple phase-frequency detector is proposed. The phase-frequency detector is composed of only two XOR gates. It simultaneously achieves low jitter and short locking time. The voltage-controlled oscillator within the PLL consists of four-stage ring oscillators which are coupled to each other and oscillate with the same frequency and a phase shift of 45. The PLL is fabricated in 0. 1Stem CMOS technology. The measured phase noise of the PLL output at 500kHz offset from the 5GHz center frequency is - 102.6dBc/Hz. The circuit exhibits a capture range of 280MHz and a low RMS jitter of 2.06ps. The power dissipation excluding the output buffers is only 21.6roW at a 1.8V supply.

克服“Locking”发散性的有限元研究进展

从克服Ｌｏｃｋｉｎｇ发散性到高性能格式的研究发展是过去十年有限元法研究的一个重要方面．本文认为所谓高性能有限元方法是一种特别的低阶位移格式，它具有如下的理论和计算优点：（１）保持物理力学问题固有的数学物理特征；（２）因此，应用于工程数值模拟，它是“鲁棒”的、高效的．按此立场，评论介绍了在计算结构力学和计算流体力学中发展的克服两类Ｌｏｃｋｉｎｇ发散性的有限元方法．

Lock-up装置在连续梁桥上的减震性能研究

以某客运专线上大跨连续梁桥为实际工程背景,研究了Lock-up装置对结构纵向抗震性能的影响。根据Lock-up装置在地震作用下具有反复锁止的受力特点,采用非线性时程分析方法,分析了锁止速度对结构减震性能的影响。结果表明:对于大跨连续梁桥,Lock-up装置能够充分发挥活动墩的抗震承载能力,有效地提高桥梁结构整体抗震性能。当锁止速度较小时,Lock-up装置可以采用大刚度连杆模拟,并假定其始终处于完全锁定状态。但当锁止速度较高时,应考虑Lock-up装置反复锁止的实际工作特点,否则应用上述计算方法所得的结果偏于不安全。

2.5Gb/s 0.18μm CMOS Clock and Data Recovery Circuit

A 2.5Gb/s clock and data recovery （CDR） circuit is designed and realized in TSMC＇s standard 0.18/μm CMOS process. The clock recovery is based on a PLL. For phase noise optimization,a dynamic phase and frequency detector （PFD） is used in the PLL. The rms jitter of the recovered 2.5GHz clock is 2.4ps and the SSB phase noise is - 111dBc/Hz at 10kHz offset. The rms jitter of the recovered 2.5Gb/s data is 3.3ps. The power consumption is 120mW.

Lock Free技术及其应用研究

多线程环境下,线程同步伴随着多线程的产生而产生,程序员对于共享内存互斥同步访问的思维已经根深蒂固。由于锁的存在,当访问互斥锁保护的共享内存时,线程首先请求锁的允许,然后才被接受访问共享内存,否则只能等待其它线程释放锁,同时锁也带来了很多负面影响。Lock Free一个崭新的多线程共享内存的同步访问技术,抛开了锁的概念,多线程平行运行,尤其是在多核时代更显优势。但Lock Free技术应用技巧性很强,难度比较大,应用范围一直非常受限,本文旨在揭示Lock Free技术应用的一般规律,使其在多核时代大放异彩。

一种采用Lock-Free同步机制的数据结构的研究

随着多核芯片在嵌入式实时系统中的广泛应用,采用传统锁机制对共享数据的访问会引起死锁、优先级翻转以及CPU饥饿现象,进而会影响系统整体性能的发挥,严重时还会导致不可估量的损失发生.为此,针对Skiplist的共享数据结构提出了一种Lock-Free的同步机制方法,对该方法的线性一致性进行了证明,并将其应用于混合关键任务的共享优先级调度队列中.经过实验,该方法在吞吐量、核利用率以及平均响应时间方面优于传统的基于锁机制的方法,有效地提升了多核运行的效率.

颈前路减压融合ROI-C^(TM)自锁系统治疗退行性颈椎病的Meta分析

目的:颈前路减压融合术是治疗退行性颈椎病的经典手术方式,钉板的使用增加了融合率及稳定性的同时,间接导致了邻近椎体退变和术后吞咽困难的发生。文章通过Meta分析方法比较ROI-C^(TM)自锁系统和传统融合器联合钉板内固定治疗退行性颈椎病患者的临床结果和并发症情况,为颈前路减压融合术中内固定方式的选择提供循证学支持。方法:检索中国知网、万方、维普、PubMed、Cochrane Library、Web of Science和Embase数据库,检索关于颈前路减压融合术中应用ROI-C^(TM)自锁系统与融合器联合钉板内固定治疗退行性颈椎病的中英文文献。检索时间范围为各数据库建库至2023年7月。由2名研究者严格按照纳入与排除标准选择文献,采用Cochrane偏倚风险工具对随机对照试验进行质量评价,NOS量表对队列研究进行质量评价。采用RevMan 5.4软件进行Meta分析。结局指标包括手术时间、术中出血量、日本骨科协会(Japanese Orthopaedic Association Scores,JOA)评分、颈椎功能障碍指数、C_(2)-C_(7)Cobb角、融合率、邻近椎体退变发生率、融合器沉降率和吞咽困难发生率。结果:共纳入13项研究,其中回顾性队列研究11项,随机对照试验2项,共1136例患者,ROI-C组569例,融合器联合钉板组567例。Meta分析结果显示:ROI-C组与融合器联合钉板组在手术时间(MD=-15.52,95%CI:-18.62至-12.42,P<0.00001),术中出血量(MD=-24.53,95%CI:-32.46至-16.61,P<0.00001),术后邻近节段退变率(RR=0.40,95%CI:0.27-0.60,P<0.00001)和术后总吞咽困难发生率(RR=0.18,95%CI:0.13-0.26,P<0.00001)均具有显著性差异。两者在术后JOA评分、颈椎功能障碍指数、C_(2)-C_(7)Cobb角、融合率和融合器沉降率方面无显著性差异(P≥0.05)。结论:在颈椎前路减压融合术中应用ROI-C^(TM)自锁系统与传统融合器联合钉板内固定治疗退行性颈椎病均可达到满意的临床效果,ROI-C^(TM)自锁系统操作更加简单,相比融合器联合钉板内固定能明显减少手术时间及术中出血量,在减少术后吞咽困难及邻近节段退变发生率等方面具有明显优势,对于跳跃型颈椎病及邻椎病翻修患者,更加推荐使用ROI-C^(TM)自锁系统。但鉴于其可能存在较高的沉降率,对于多节段且合并融合器沉降高危因素如骨质疏松、椎体终板破损的退行性颈椎病患者,仍建议使用融合器联合钉板内固定。

桡骨远端C1型骨折三种内固定方式的有限元分析

背景:桡骨远端C1型骨折属于关节内不稳定型骨折,治疗上存在较大的难度。目前对桡骨远端骨折不同内固定接骨板的临床研究较少,缺乏多种内固定接骨板的生物力学对比研究,在内固定接骨板的选用上仍存在争议。目的:通过有限元分析法比较不同内固定接骨板在桡骨远端C1型骨折治疗中的生物力学特性。方法:使用一名健康女性志愿者的桡骨模型,顺序导入Mimics 21.0、Geomagic Wrap 2017、Solid Works 2021等软件进行处理,制作桡骨远端C1型骨折模型。根据厂家提供的接骨板数据,分别建立桡骨远端掌侧斜T形锁定板、桡骨远端掌侧蝶形锁定板、桡骨远端掌侧万向锁定板和螺钉的三维模型,并且和骨折模型进行装配,在ANSYS 19.0中赋予材料属性,设定各接触面相互作用关系并定义载荷及边界条件,模拟其腕关节压缩、背弯、掌屈和扭转等4种载荷工况,比较其生物力学性能。结果与结论:①3组内固定模型在4种载荷工况下,内固定模型整体位移主要集中在桡骨远端关节面上;模型在背弯、掌屈和扭转载荷工况下的最大位移是轴向载荷下位移的2-6倍,表明轴向载荷工况下内固定系统最稳定;②内固定上的应力远大于骨折块上的应力,内固定物应力主要集中于接骨板在骨折断端附近区域,其中万向锁定板和蝶形锁定板应力分布较为均匀,斜T形锁定板应力集中现象最为明显;③在压缩和扭转载荷下,骨折块的应力主要集中在螺钉孔周围,掌屈和背伸载荷下则是从桡骨远端向近端逐步扩展;在同样的载荷工况下,斜T形锁定板固定状态下骨折块应力最大,万向锁定板固定系统骨折块所受应力峰值最低,蝶形锁定板与万向锁定板固定状态下的骨折块峰值应力仅仅相差0.2-6.0 MPa;④相比于斜T形锁定板和蝶形锁定板,万向锁定板在桡骨远端C1型骨折内固定中应力分布更均匀,固定模型关节面位移更小、稳定性更佳。

软件加密系统“清华LOCK”的设计与实现

本文论述了软件加密的原理与方法，提出并实现了一个多功能软件加密系统“清华ＬＯＣＫ”。它具有使用灵活方便、运行效率高、安全性强的特点，能有效地抵御目前所知的一切静态或动态跟踪手段，是一个很有前途的软件加密系统。

Lock-up装置的作用机理与分析模型

为探讨Lock-up装置的分析模型,介绍了其构造、阐述了其作用机理,给出了Lock-up装置阻尼力的力学模型并提出了相应的数值模拟方法。基于某铁路桥梁,建立全桥有限空间模型,采用文中提出的模拟方法进行了Lock-up装置的减震性能分析,通过与常用的刚性连杆或主从约束模拟方法的比较,明确了刚性连杆模拟方法的适用条件。结果表明,Lock-up装置的地震作用过程比较复杂,当Lock-up装置能够激发出极大的阻尼力时,文中的模拟方法与常用的刚性连杆或主从约束模拟方法结果非常接近,通常情况按刚性连杆或主从约束模拟方法得到的结果偏大。

Hem-o-lock夹在腹膜后腹腔镜下肾盂旁囊肿去顶术中的疗效评估

目的:探讨Hem-o-lock夹在后腹腔镜肾盂旁囊肿去顶术中的疗效。方法:7例肾盂旁囊肿患者行后腹腔镜肾盂旁囊肿去顶+囊壁两侧各夹Hem-o-lock一枚。结果:7例手术均成功;手术时间平均60min;术中出血量平均30ml;术后住院时间平均4.2d;7例术后随访6～24个月,均无复发。结论:后腹腔镜肾盂旁囊肿去顶+囊壁两侧各夹Hem-o-lock一枚可有效减少肾盂囊肿复发,且手术操作安全简单。

基于NordLock楔锁原理的双螺母滚珠丝杠副的创新设计与性能分析

针对国产滚珠丝杠副常常出现的因加工误差、滚道磨损等因素导致的预紧力丧失的难题,将NordLock楔锁特征应用于滚珠丝杠副的结构设计中,提出了一种新型预紧滚珠丝杠副。该预紧机构由左、右两个楔锁垫片组成,使双螺母与丝杠轴产生相对位移,从而产生轴向预紧力;同时,两垫片的楔锁效应使得预紧力大小保持不变。根据楔锁效应和滚珠丝杠副的结构参数,确定了楔形预紧垫片的关键结构参数。应用SolidWorks建立了三维几何模型,应用Ansys有限元软件对新型滚珠丝杠副进行了瞬态动力学分析和模态分析。结果表明,这种新型结构能够有效地实现自我预紧,有望成为一种具有良好应用前景的高可靠性、长寿命的滚珠丝杠副。

Influence of Seawall Line Choice on Tide Lock Drainage in Tidal Flat Inning——Cangdongpian Inning Area on the west part of Tiaozini Sand as a case study

Most of the flood from the wide inner lowland plain discharges through tide locks on coast, and the influence of tidal flat inning projects on the tide lock drainage must be solved by seawall line choice. Taking the Cangdongpian inning area on the west side of Tiaozini Sand as a case study, the paper analyzed the compages and validity of ebb tide water to maintain the flood discharge creek below the tide lock for different projects of seawall line. Result indicates that a rational seawall line program has little influence on the flood discharge of lock during the mean tide or general spring tides, but has certain influences during a storm surge or an extreme spring tide in autumn. However it could be resolved by several times of artificial scour on the creek.