In accordance with the regulations as stipulated in the Pro-visions of the Customs of the People’s Republic of China on Ex-ternal Audit, the Customs officers engaged in external audit shalluse the Certificate of Exte...In accordance with the regulations as stipulated in the Pro-visions of the Customs of the People’s Republic of China on Ex-ternal Audit, the Customs officers engaged in external audit shalluse the Certificate of External Audit of the Customs (hereinafterreferred to as Certificate) as of June 5, 1997. The Certificate has ablack leather outer covering and is inlaid inside with a pierced andguilded customs emblem, which consists of the red national em-blem in its upper part, and a key and a truncheon encircled by earsof wheat in its lower part. Put in a leather covering, the Certificateis a card sealed up with plastics, on which there is a bareheadedcolour photo of the holder in the Customs uniform and with a展开更多
There are two different genetic types of recently deposited silts widely distributing in Huaibei Plain of Anhui Province:flooding deposited silt of Yellow River and Huaihe River.These recently deposited silts have the...There are two different genetic types of recently deposited silts widely distributing in Huaibei Plain of Anhui Province:flooding deposited silt of Yellow River and Huaihe River.These recently deposited silts have the following unique characteristics:new formation age,feeble consolidation degree。展开更多
BACKGROUND Little is known about the engagement in hepatitis C virus(HCV)care and completion of HCV treatment in people living with human immunodeficiency virus(HIV)(PLWH)who have HCV coinfection in the Asia-Pacific r...BACKGROUND Little is known about the engagement in hepatitis C virus(HCV)care and completion of HCV treatment in people living with human immunodeficiency virus(HIV)(PLWH)who have HCV coinfection in the Asia-Pacific region.Examining the HCV care cascade can identify barriers to the completion of HCV treatment and facilitate achievement of HCV micro-elimination in PLWH.AIM To investigate the care cascade of incident HCV infections among PLWH in Taiwan.METHODS PLWH with incident HCV infections,defined as HCV seroconversion,were retrospectively identified by sequential anti-HCV testing of all archived blood samples at National Taiwan University Hospital between 2011 and 2018.All PLWH with incident HCV infections were followed until December 31,2019.The care cascade of HCV examined included all incident HCV-infected patients,the percentages of anti-HCV antibodies detected by HIV-treating physicians in clinical care,plasma HCV RNA load tested,HCV RNA positivity diagnosed,referral to treatment assessment made,anti-HCV treatment initiated,and sustained virologic response achieved.Those who had HCV seroconversion during the interferon(IFN)era(2011–2016)and the direct-acting antiviral(DAA)era(2017–2018)were analyzed separately.The duration of HCV viremia—from the date of seroconversion to viral clearance by treatments or until the end of observation—and the incidence of sexually transmitted infections(STIs)during the HCV viremic period were estimated.RESULTS During the study period,287 of 3495(8.2%)PLWH(92.3%being men who have sex with men)who were HCV-seronegative at baseline developed HCV seroconversion by retrospective testing of all archived blood samples.Of the 287 incident HCV infections,277(96.5%)had anti-HCV antibodies detected by HIV-treating physicians,270(94.1%)had plasma HCV RNA determined and 251(87.5%)tested positive for HCV RNA.Of those with HCV viremia,226(78.7%)were referred to treatment assessment,215(74.9%)initiated anti-HCV treatment,and 202(70.4%)achieved viral clearance.Compared with that in the IFN era,the median interval from HCV seroconversion by retrospective testing to detection of HCV seropositivity by HIV-treating physicians was significantly shorter in the DAA era{179 d[interquartile range(IQR)87-434]vs 92 d(IQR 57-173);P<0.001}.The incidence rate of STIs in the DAA vs the IFN era was 50.5 per 100 person-years of follow-up(PYFU)and 38.5 per 100 PYFU,respectively,with an incidence rate ratio of 1.31(95%confidence interval 0.96-1.77),while the duration of HCV viremia was 380 d(IQR 274-554)and 735 d(IQR 391-1447)(P<0.001),respectively.CONCLUSION While anti-HCV therapies are effective in achieving viral clearance,our study suggests more efforts are needed to expedite the linkage of PLWH diagnosed with incident HCV infections to HCV treatment.展开更多
IN recent years, a series of environmental problems have attracted wide attention in the world.As environmental changes can result from both the operations of natural factors and human ac-tivities, the international s...IN recent years, a series of environmental problems have attracted wide attention in the world.As environmental changes can result from both the operations of natural factors and human ac-tivities, the international science community has the common opinion that environmental prob-lems should be studied in a broader perspect. In other words, the earth environment should beregarded as an entity that consists of many interactive and interrelated parts. Highlighted展开更多
This study shows that the principle of a recently proposed connnon-path laser interferometer containing a planar grating is nonexistent and apparently caused by a mathematical derivation error. Both p- and s-polarized...This study shows that the principle of a recently proposed connnon-path laser interferometer containing a planar grating is nonexistent and apparently caused by a mathematical derivation error. Both p- and s-polarized beams ill the proposed setup experience once the +lst-order diffraction and once the lst-order diffraction by tile grating. As a result, the phase of each beam remains unchanged and the interference fringes formed by the two beams are not expected to move when the grating is translated in the grating vector direction. We perform an experiment to confirm this prediction. Both our analysis and experimental observation cast doubt on the experimental results of the authors who proposed the interferometer.展开更多
Last week, Chinese Premier Wen Jiabao headed a delegation to New Zealand, which was part of his South Pacific trip, to discuss trade and a potential free trade area between the two countries. Ahead of the visit, Beiji...Last week, Chinese Premier Wen Jiabao headed a delegation to New Zealand, which was part of his South Pacific trip, to discuss trade and a potential free trade area between the two countries. Ahead of the visit, Beijing Review spoke with New Zealand Ambassador to China Tony Browne on his country's trade relationship with China.展开更多
在外研社高中英语第七册(山东省专用)第五单元<<Ethnic Culture>>阅读课文中,有这样一句话:'For example,it is the women who run Naxi Society,and until recently,Naxi women inherited all property.'课文附录...在外研社高中英语第七册(山东省专用)第五单元<<Ethnic Culture>>阅读课文中,有这样一句话:'For example,it is the women who run Naxi Society,and until recently,Naxi women inherited all property.'课文附录部分(第133页)对此句的翻译是:展开更多
This paper celebrates Professor Yongqi GAO's significant achievement in the field of interdisciplinary studies within the context of his final research project Arctic Climate Predictions: Pathways to Resilient Sus...This paper celebrates Professor Yongqi GAO's significant achievement in the field of interdisciplinary studies within the context of his final research project Arctic Climate Predictions: Pathways to Resilient Sustainable Societies-ARCPATH(https://www.svs.is/en/projects/finished-projects/arcpath). The disciplines represented in the project are related to climatology, anthropology, marine biology, economics, and the broad spectrum of social-ecological studies. Team members were drawn from the Nordic countries, Russia, China, the United States, and Canada. The project was transdisciplinary as well as interdisciplinary as it included collaboration with local knowledge holders. ARCPATH made significant contributions to Arctic research through an improved understanding of the mechanisms that drive climate variability in the Arctic. In tandem with this research, a combination of historical investigations and social, economic, and marine biological fieldwork was carried out for the project study areas of Iceland, Greenland, Norway, and the surrounding seas, with a focus on the joint use of ocean and sea-ice data as well as social-ecological drivers. ARCPATH was able to provide an improved framework for predicting the near-term variation of Arctic climate on spatial scales relevant to society, as well as evaluating possible related changes in socioeconomic realms. In summary, through the integration of information from several different disciplines and research approaches, ARCPATH served to create new and valuable knowledge on crucial issues, thus providing new pathways to action for Arctic communities.展开更多
Zinc-ion batteries(ZIBs) are recognized as potential energy storage devices due to their advantages of low cost, high energy density, and environmental friendliness. However, zinc anodes are subject to unavoidable zin...Zinc-ion batteries(ZIBs) are recognized as potential energy storage devices due to their advantages of low cost, high energy density, and environmental friendliness. However, zinc anodes are subject to unavoidable zinc dendrites, passivation, corrosion, and hydrogen evolution reactions during the charging and discharging of batteries, becoming obstacles to the practical application of ZIBs. Appropriate zinc metal-free anodes provide a higher working potential than metallic zinc anodes, effectively solving the problems of zinc dendrites, hydrogen evolution, and side reactions during the operation of metallic zinc anodes. The improvement in the safety and cycle life of batteries creates conditions for further commercialization of ZIBs. Therefore, this work systematically introduces the research progress of zinc metal-free anodes in “rocking chair” ZIBs. Zinc metal-free anodes are mainly discussed in four categories: transition metal oxides,transition metal sulfides, MXene(two dimensional transition metal carbide) composites, and organic compounds, with discussions on their properties and zinc storage mechanisms. Finally, the outlook for the development of zinc metal-free anodes is proposed. This paper is expected to provide a reference for the further promotion of commercial rechargeable ZIBs.展开更多
Undoubtedly,the enormous progress observed in recent years in the Ni-rich layered cathode materials has been crucial in terms of pushing boundaries of the Li-ion battery(LIB)technology.The achieved improvements in the...Undoubtedly,the enormous progress observed in recent years in the Ni-rich layered cathode materials has been crucial in terms of pushing boundaries of the Li-ion battery(LIB)technology.The achieved improvements in the energy density,cyclability,charging speed,reduced costs,as well as safety and stability,already contribute to the wider adoption of LIBs,which extends nowadays beyond mobile electronics,power tools,and electric vehicles,to the new range of applications,including grid storage solutions.With numerous published papers and broad reviews already available on the subject of Ni-rich oxides,this review focuses more on the most recent progress and new ideas presented in the literature references.The covered topics include doping and composition optimization,advanced coating,concentration gradient and single crystal materials,as well as innovations concerning new electrolytes and their modification,with the application of Ni-rich cathodes in solid-state batteries also discussed.Related cathode materials are briefly mentioned,with the high-entropy approach and zero-strain concept presented as well.A critical overview of the still unresolved issues is given,with perspectives on the further directions of studies and the expected gains provided.展开更多
Depression,a common mental illness,seriously affects the health of individuals and has deleterious effects on society.The prevention and treatment of depression has drawn the attention of many researchers and has beco...Depression,a common mental illness,seriously affects the health of individuals and has deleterious effects on society.The prevention and treatment of depression has drawn the attention of many researchers and has become an important social issue.The treatment strategies for depression include drugs,psychotherapy,and physiotherapy.Drug therapy is ineffective in some patients and psychotherapy has treatment limitations.As a reliable adjuvant therapy,physiotherapy compensates for the shortcomings of drug and psychotherapy and effectively reduces the disease recurrence rate.Physiotherapy is more scientific and rigorous,its methods are diverse,and to a certain extent,provides more choices for the treatment of depression.Physiotherapy can relieve symptoms in many ways,such as by improving the levels of neurobiochemical molecules,inhibiting the inflammatory response,regulating the neuroendocrine system,and increasing neuroplasticity.Physiotherapy has biological effects similar to those of antidepressants and may produce a superimposed impact when combined with other treatments.This article summarizes the findings on the use of physiotherapy to treat patients with depression over the past five years.It also discusses several methods of physiotherapy for treating depression from the aspects of clinical effect,mechanism of action,and disadvantages,thereby serving as a reference for the in-depth development of physiotherapy research.展开更多
Objective:To analyze the clinical efficacy,progression-free survival,and safety of anlotinib in the treatment of advanced lung cancer.Methods:A retrospective analysis was conducted using data from 60 patients with adv...Objective:To analyze the clinical efficacy,progression-free survival,and safety of anlotinib in the treatment of advanced lung cancer.Methods:A retrospective analysis was conducted using data from 60 patients with advanced lung cancer treated with anlotinib from May 2019 to May 2021.This analysis aimed to comprehensively evaluate the clinical efficacy,progression-free survival,and adverse reactions of anlotinib.Results:The median progression-free survival(PFS)for the 60 patients was 5.79 months,with an overall response rate(ORR)of 21%and a disease control rate(DCR)of 90%.In the first-line group,the median PFS was 6.20 months,ORR was 76.92%,and DCR was 84.61%.The second-line group showed a median PFS of 6.30 months,ORR of 28.57%,and DCR of 90.48%.In the third-line group,the median PFS was 5.34 months,ORR was 19.23%,and DCR was 92.30%.The single-agent group exhibited a median PFS of 5.09 months,ORR of 23.33%,and DCR of 76.67%.In the combination group,the median PFS was 6.53 months,ORR was 46.67%,and DCR was 100%.The combination group demonstrated a significantly higher medication effect than the single-drug group,and adverse drug reactions were mostly grade 1-2.Conclusion:Anlotinib exhibits a better disease control rate and survival benefit in the treatment of advanced lung cancer.The combination effect is superior to monotherapy,with relatively controllable adverse effects.展开更多
Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and...Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC.展开更多
During the Sino\|American Expedition to Mt. Qomolangma in May 1997, a 41m ice core was recovered from an elevation of 6500m from the northern branch firn basin of the Far East Rongbuk Glacier in Mt. Everest. The ice c...During the Sino\|American Expedition to Mt. Qomolangma in May 1997, a 41m ice core was recovered from an elevation of 6500m from the northern branch firn basin of the Far East Rongbuk Glacier in Mt. Everest. The ice core was dated down to 1814 by counting δ 18 O peaks and referring to the variations of β activity and major ion concentrations. The average annual accumulation is 224mm (ice equivalent). Five cold periods and five warm periods have been reconstructed from the ice core for the last 200 years and the general tendency of climatic change is warming, which is agree with the temperature change in the Northern Hemisphere. Also the climatic records in Far East Rongbuk ice core has good agreement with that in the Guliya ice core. This indicates that the climatic changes are consistent in the northwestern and southern Qinghai—Tibetan Plateau, and the ranges of climatic changes are larger in southern Plateau than that in northwestern Plateau. Though the δ 18 O variations has some negatively correlation with precipitation amount for short time scale, these do not effect δ 18 O changes reflecting temperature for long time scale.展开更多
The recently synthesized first 4d transition-metal oxide-hydride LaSr3NiRuO4H4 with the unusual high H:O ratio surprisingly displays no magnetic order down to 1.8 K. This is in sharp contrast to the similar unusual lo...The recently synthesized first 4d transition-metal oxide-hydride LaSr3NiRuO4H4 with the unusual high H:O ratio surprisingly displays no magnetic order down to 1.8 K. This is in sharp contrast to the similar unusual low-valent Ni^+-Ru^2+ layered oxide LaSrNiRuO4 which has a rather high ferromagnetic(FM) ordering Curie temperature TC^250 K. Using density functional calculations with the aid of crystal field level diagrams and superexchange pictures, we find that the contrasting magnetism is due to the distinct spin-orbital states of the Ru^2+ions(in addition to the common Ni+S = 1/2 state but with a different orbital state): the Ru^2+S = 0 state in LaSr3NiRuO4H4, but the Ru^2+S= 1 state in LaSrNiRuO4. The Ru^2+S = 0 state has the(xy)^2(xz, yz)^4 occupation due to the RuH4O2 octahedral coordination, and then the nonmagnetic Ru2+ions dilute the S= 1/2 Ni^+ sublattice which consequently has a very weak antiferromagnetic superexchange and thus accounts for the presence of no magnetic order down to 1.8 K in LaSr3NiRuO4H4. In strong contrast, the Ru^2+S = 1 state in LaSrNiRuO4 has the(3z^2-r^2)^2(xz, yz)^3(xy)^1 occupation due to the planar square RuO4 coordination, and then the multi-orbital FM superexchange between the S= 1/2 Ni^+ and S= 1 Ru^2+ions gives rise to the high TC in LaSrNiRuO4. This work highlights the importance of spin-orbital states in determining the distinct magnetism.展开更多
Based on fault geometric features,composite pattern,faulting land-forms and seismic data,this paper discussed the activity behavior along the northern segment of the Anninghe fault(from Xichang to Shimian)since the La...Based on fault geometric features,composite pattern,faulting land-forms and seismic data,this paper discussed the activity behavior along the northern segment of the Anninghe fault(from Xichang to Shimian)since the Late Pleistocene.The fault can be divided into three active segments by discrepancies of their activity:the segment from Xichang to Mianning,the segment from Mianning to Zimakua,and the segment from Zimakua to Tianwan.The southern segment has the background of occurrence of great earthquakes,but the middle and the northern segments can generate strong and moderate events respectively.According to the features of quartz from fault gouges by scanning electron microscopy(SEM),this paper discussed the movement features along the fault and indicated the stick-slipping feature on the segment from Xichang to Zimakua,the creeping feature on the segment from Jiziping to Tianwan and the transitional feature on the segment in between.展开更多
Cassava is a multi-purpose crop for food, feed and industrial raw materi- als (starch, modified starch and ethanol fuel). Cassava leaf, an important by-product of cassava industry, is rich in protein, minerals and f...Cassava is a multi-purpose crop for food, feed and industrial raw materi- als (starch, modified starch and ethanol fuel). Cassava leaf, an important by-product of cassava industry, is rich in protein, minerals and flavonoids. This article reviews the utilization of cassava leaf in the production of food, animal feed and antioxidants in recent years, analyzes the effects of anti-nutritional factors and extraction of an- tioxidative flavonoids on the utilization of cassava leaf, finally puts forward the main problems in the utilization of cassava leaf, to provide a theoretical basis for the ba- sic research of cassava leaf.展开更多
An integration processing system of three-dimensional laser scanning information visualization in goaf was developed. It is provided with multiple functions, such as laser scanning information management for goaf, clo...An integration processing system of three-dimensional laser scanning information visualization in goaf was developed. It is provided with multiple functions, such as laser scanning information management for goaf, cloud data de-noising optimization, construction, display and operation of three-dimensional model, model editing, profile generation, calculation of goaf volume and roof area, Boolean calculation among models and interaction with the third party soft ware. Concerning this system with a concise interface, plentiful data input/output interfaces, it is featured with high integration, simple and convenient operations of applications. According to practice, in addition to being well-adapted, this system is favorably reliable and stable.展开更多
Rare earth market changes the upward trend recently and began to shock. Price of didymium oxide has fallen from the previous high of 510,000 yuan/ton to 460,000 yuan/ton on Sep. 28. Besides the rational revise of the ...Rare earth market changes the upward trend recently and began to shock. Price of didymium oxide has fallen from the previous high of 510,000 yuan/ton to 460,000 yuan/ton on Sep. 28. Besides the rational revise of the former price surging, the other reason for the price drop is the slack demand from downstream industries. However, the rare earth groups began cease production to guarantee the market price recently. This is definitely good news for it can ease the oversupply recently. But, whether rare earth price can be backed is finally decided by the demand from downstream industries.展开更多
文摘In accordance with the regulations as stipulated in the Pro-visions of the Customs of the People’s Republic of China on Ex-ternal Audit, the Customs officers engaged in external audit shalluse the Certificate of External Audit of the Customs (hereinafterreferred to as Certificate) as of June 5, 1997. The Certificate has ablack leather outer covering and is inlaid inside with a pierced andguilded customs emblem, which consists of the red national em-blem in its upper part, and a key and a truncheon encircled by earsof wheat in its lower part. Put in a leather covering, the Certificateis a card sealed up with plastics, on which there is a bareheadedcolour photo of the holder in the Customs uniform and with a
文摘There are two different genetic types of recently deposited silts widely distributing in Huaibei Plain of Anhui Province:flooding deposited silt of Yellow River and Huaihe River.These recently deposited silts have the following unique characteristics:new formation age,feeble consolidation degree。
基金Supported by National Taiwan University Hospital,Taipei,Taiwan,No.NTUH106-003347(to Sun HY).
文摘BACKGROUND Little is known about the engagement in hepatitis C virus(HCV)care and completion of HCV treatment in people living with human immunodeficiency virus(HIV)(PLWH)who have HCV coinfection in the Asia-Pacific region.Examining the HCV care cascade can identify barriers to the completion of HCV treatment and facilitate achievement of HCV micro-elimination in PLWH.AIM To investigate the care cascade of incident HCV infections among PLWH in Taiwan.METHODS PLWH with incident HCV infections,defined as HCV seroconversion,were retrospectively identified by sequential anti-HCV testing of all archived blood samples at National Taiwan University Hospital between 2011 and 2018.All PLWH with incident HCV infections were followed until December 31,2019.The care cascade of HCV examined included all incident HCV-infected patients,the percentages of anti-HCV antibodies detected by HIV-treating physicians in clinical care,plasma HCV RNA load tested,HCV RNA positivity diagnosed,referral to treatment assessment made,anti-HCV treatment initiated,and sustained virologic response achieved.Those who had HCV seroconversion during the interferon(IFN)era(2011–2016)and the direct-acting antiviral(DAA)era(2017–2018)were analyzed separately.The duration of HCV viremia—from the date of seroconversion to viral clearance by treatments or until the end of observation—and the incidence of sexually transmitted infections(STIs)during the HCV viremic period were estimated.RESULTS During the study period,287 of 3495(8.2%)PLWH(92.3%being men who have sex with men)who were HCV-seronegative at baseline developed HCV seroconversion by retrospective testing of all archived blood samples.Of the 287 incident HCV infections,277(96.5%)had anti-HCV antibodies detected by HIV-treating physicians,270(94.1%)had plasma HCV RNA determined and 251(87.5%)tested positive for HCV RNA.Of those with HCV viremia,226(78.7%)were referred to treatment assessment,215(74.9%)initiated anti-HCV treatment,and 202(70.4%)achieved viral clearance.Compared with that in the IFN era,the median interval from HCV seroconversion by retrospective testing to detection of HCV seropositivity by HIV-treating physicians was significantly shorter in the DAA era{179 d[interquartile range(IQR)87-434]vs 92 d(IQR 57-173);P<0.001}.The incidence rate of STIs in the DAA vs the IFN era was 50.5 per 100 person-years of follow-up(PYFU)and 38.5 per 100 PYFU,respectively,with an incidence rate ratio of 1.31(95%confidence interval 0.96-1.77),while the duration of HCV viremia was 380 d(IQR 274-554)and 735 d(IQR 391-1447)(P<0.001),respectively.CONCLUSION While anti-HCV therapies are effective in achieving viral clearance,our study suggests more efforts are needed to expedite the linkage of PLWH diagnosed with incident HCV infections to HCV treatment.
文摘IN recent years, a series of environmental problems have attracted wide attention in the world.As environmental changes can result from both the operations of natural factors and human ac-tivities, the international science community has the common opinion that environmental prob-lems should be studied in a broader perspect. In other words, the earth environment should beregarded as an entity that consists of many interactive and interrelated parts. Highlighted
文摘This study shows that the principle of a recently proposed connnon-path laser interferometer containing a planar grating is nonexistent and apparently caused by a mathematical derivation error. Both p- and s-polarized beams ill the proposed setup experience once the +lst-order diffraction and once the lst-order diffraction by tile grating. As a result, the phase of each beam remains unchanged and the interference fringes formed by the two beams are not expected to move when the grating is translated in the grating vector direction. We perform an experiment to confirm this prediction. Both our analysis and experimental observation cast doubt on the experimental results of the authors who proposed the interferometer.
文摘Last week, Chinese Premier Wen Jiabao headed a delegation to New Zealand, which was part of his South Pacific trip, to discuss trade and a potential free trade area between the two countries. Ahead of the visit, Beijing Review spoke with New Zealand Ambassador to China Tony Browne on his country's trade relationship with China.
文摘在外研社高中英语第七册(山东省专用)第五单元<<Ethnic Culture>>阅读课文中,有这样一句话:'For example,it is the women who run Naxi Society,and until recently,Naxi women inherited all property.'课文附录部分(第133页)对此句的翻译是:
基金the Nord Forsk-funded Nordic Centre of Excellence project (Award 766654) Arctic Climate Predictions: Pathways to Resilient,Sustainable Societies (ARCPATH)National Science Foundation Award 212786 Synthesizing Historical Sea-Ice Records to Constrain and Understand Great Sea-Ice Anomalies (ICEHIST) PI Martin MILES,Co-PI Astrid OGILVIE+12 种基金American-Scandinavian Foundation Award Whales and Ice: Marine-mammal subsistence use in times of famine in Iceland ca.A.D.1600–1900 (ICEWHALE),PI Astrid OGILVIESocial Sciences and Humanities Research Council of Canada Award 435-2018-0194 Northern Knowledge for Resilience,Sustainable Environments and Adaptation in Coastal Communities (NORSEACC),PI Leslie KING,Co-PI,Astrid OGILVIEToward Just,Ethical and Sustainable Arctic Economies,Environments and Societies (JUSTNORTH).EU H2020 (https://www.svs.is/en/ projects/ongoing-projects/justnorth-2020-2023)INTO THE OCEANIC by Elizabeth OGILVIE and Robert PAGE (https://www.intotheo ceanic.org/introduction)Proxy Assimilation for Reconstructing Climate and Improving Model (PARCIM) funded by the Bjerknes Centre for Climate Research,led by Fran?ois COUNILLON,PI Noel KEENLYSIDEAccelerated Arctic and Tibetan Plateau Warming: Processes and Combined Impact on Eurasian Climate (COMBINED),Research Council of Norway (Grant No.328935),Led by Noel KEENLYSIDEArven etter Nansen programme (the Nansen Legacy Project),Research Council of Norway (Grant No.276730),PI Noel KEENLYSIDEBjerknes Climate Prediction Unit,funded by Trond Mohn Foundation (Grant BFS2018TMT01) Centre for Research-based Innovation Climate Futures,Research Council of Norway (Grant No.309562),PIs Noel KEENLYSIDE,Francois COUNILLONDeveloping and Advancing Seasonal Predictability of Arctic Sea Ice (4ICE),Research Council of Norway (Grant No.254765),PI Francois COUNILLONTropical and South Atlantic Climate-Based Marine Ecosystem Prediction for Sustainable Management (TRIATLAS) European Union Horizon 2020 (Grant No.817578),led by Noel KEENLYSIDE,PI Fran?ois COUNILLONImpetus4Change,European Union Horizon Europe (Grant No.101081555),PIs Noel KEENLYSIDE,Fran?ois COUNILLONLaboratory for Climate Predictability,Russian Megagrant funded by Ministry of Science and Higher Education of the Russian Federation (Agreement No.075-15-2021-577),led by Noel KEENLYSIDE,PI Segey GULEVRapid Arctic Environmental Changes: Implications for Well-Being,Resilience and Evolution of Arctic Communities (RACE),Belmont Forum (RCN Grant No.312017),PIs Sergey GULEV and Noel KEENLYSIDE。
文摘This paper celebrates Professor Yongqi GAO's significant achievement in the field of interdisciplinary studies within the context of his final research project Arctic Climate Predictions: Pathways to Resilient Sustainable Societies-ARCPATH(https://www.svs.is/en/projects/finished-projects/arcpath). The disciplines represented in the project are related to climatology, anthropology, marine biology, economics, and the broad spectrum of social-ecological studies. Team members were drawn from the Nordic countries, Russia, China, the United States, and Canada. The project was transdisciplinary as well as interdisciplinary as it included collaboration with local knowledge holders. ARCPATH made significant contributions to Arctic research through an improved understanding of the mechanisms that drive climate variability in the Arctic. In tandem with this research, a combination of historical investigations and social, economic, and marine biological fieldwork was carried out for the project study areas of Iceland, Greenland, Norway, and the surrounding seas, with a focus on the joint use of ocean and sea-ice data as well as social-ecological drivers. ARCPATH was able to provide an improved framework for predicting the near-term variation of Arctic climate on spatial scales relevant to society, as well as evaluating possible related changes in socioeconomic realms. In summary, through the integration of information from several different disciplines and research approaches, ARCPATH served to create new and valuable knowledge on crucial issues, thus providing new pathways to action for Arctic communities.
基金financially supported by the National Natural Science Foundation of China (Nos.51872090 and51772097)the Hebei Natural Science Fund for Distinguished Young Scholar,China (No.E2019209433)+2 种基金the Youth Talent Program of Hebei Provincial Education Department,China (No.BJ2018020)the Natural Science Foundation of Hebei Province,China (No.E2020209151)the Science and Technology Project of Hebei Education Department,China (No.SLRC2019028)。
文摘Zinc-ion batteries(ZIBs) are recognized as potential energy storage devices due to their advantages of low cost, high energy density, and environmental friendliness. However, zinc anodes are subject to unavoidable zinc dendrites, passivation, corrosion, and hydrogen evolution reactions during the charging and discharging of batteries, becoming obstacles to the practical application of ZIBs. Appropriate zinc metal-free anodes provide a higher working potential than metallic zinc anodes, effectively solving the problems of zinc dendrites, hydrogen evolution, and side reactions during the operation of metallic zinc anodes. The improvement in the safety and cycle life of batteries creates conditions for further commercialization of ZIBs. Therefore, this work systematically introduces the research progress of zinc metal-free anodes in “rocking chair” ZIBs. Zinc metal-free anodes are mainly discussed in four categories: transition metal oxides,transition metal sulfides, MXene(two dimensional transition metal carbide) composites, and organic compounds, with discussions on their properties and zinc storage mechanisms. Finally, the outlook for the development of zinc metal-free anodes is proposed. This paper is expected to provide a reference for the further promotion of commercial rechargeable ZIBs.
基金supported by the program“Excellence Initiative-Research University”for the AGH University of Krakow(IDUB AGH,No.501.696.7996,Action 4,ID 6354)partially supported by the AGH University of Krakow under No.16.16.210.476.
文摘Undoubtedly,the enormous progress observed in recent years in the Ni-rich layered cathode materials has been crucial in terms of pushing boundaries of the Li-ion battery(LIB)technology.The achieved improvements in the energy density,cyclability,charging speed,reduced costs,as well as safety and stability,already contribute to the wider adoption of LIBs,which extends nowadays beyond mobile electronics,power tools,and electric vehicles,to the new range of applications,including grid storage solutions.With numerous published papers and broad reviews already available on the subject of Ni-rich oxides,this review focuses more on the most recent progress and new ideas presented in the literature references.The covered topics include doping and composition optimization,advanced coating,concentration gradient and single crystal materials,as well as innovations concerning new electrolytes and their modification,with the application of Ni-rich cathodes in solid-state batteries also discussed.Related cathode materials are briefly mentioned,with the high-entropy approach and zero-strain concept presented as well.A critical overview of the still unresolved issues is given,with perspectives on the further directions of studies and the expected gains provided.
文摘Depression,a common mental illness,seriously affects the health of individuals and has deleterious effects on society.The prevention and treatment of depression has drawn the attention of many researchers and has become an important social issue.The treatment strategies for depression include drugs,psychotherapy,and physiotherapy.Drug therapy is ineffective in some patients and psychotherapy has treatment limitations.As a reliable adjuvant therapy,physiotherapy compensates for the shortcomings of drug and psychotherapy and effectively reduces the disease recurrence rate.Physiotherapy is more scientific and rigorous,its methods are diverse,and to a certain extent,provides more choices for the treatment of depression.Physiotherapy can relieve symptoms in many ways,such as by improving the levels of neurobiochemical molecules,inhibiting the inflammatory response,regulating the neuroendocrine system,and increasing neuroplasticity.Physiotherapy has biological effects similar to those of antidepressants and may produce a superimposed impact when combined with other treatments.This article summarizes the findings on the use of physiotherapy to treat patients with depression over the past five years.It also discusses several methods of physiotherapy for treating depression from the aspects of clinical effect,mechanism of action,and disadvantages,thereby serving as a reference for the in-depth development of physiotherapy research.
基金Key R&D Program of Yan’an Municipal Bureau of Science and Technology(Project No.2021YF-21)。
文摘Objective:To analyze the clinical efficacy,progression-free survival,and safety of anlotinib in the treatment of advanced lung cancer.Methods:A retrospective analysis was conducted using data from 60 patients with advanced lung cancer treated with anlotinib from May 2019 to May 2021.This analysis aimed to comprehensively evaluate the clinical efficacy,progression-free survival,and adverse reactions of anlotinib.Results:The median progression-free survival(PFS)for the 60 patients was 5.79 months,with an overall response rate(ORR)of 21%and a disease control rate(DCR)of 90%.In the first-line group,the median PFS was 6.20 months,ORR was 76.92%,and DCR was 84.61%.The second-line group showed a median PFS of 6.30 months,ORR of 28.57%,and DCR of 90.48%.In the third-line group,the median PFS was 5.34 months,ORR was 19.23%,and DCR was 92.30%.The single-agent group exhibited a median PFS of 5.09 months,ORR of 23.33%,and DCR of 76.67%.In the combination group,the median PFS was 6.53 months,ORR was 46.67%,and DCR was 100%.The combination group demonstrated a significantly higher medication effect than the single-drug group,and adverse drug reactions were mostly grade 1-2.Conclusion:Anlotinib exhibits a better disease control rate and survival benefit in the treatment of advanced lung cancer.The combination effect is superior to monotherapy,with relatively controllable adverse effects.
文摘Our knowledge of renal cell carcinoma(RCC) is rapidly expanding. For those who diagnose and treat RCC, it is important to understand the new developments. In recent years, many new renal tumors have been described and defined, and our understanding of the biology and clinical correlates of these tumors is changing. Evolving concepts in Xp11 translocation carcinoma, mucinous tubular and spindle cell carcinoma, multilocular cystic clear cell RCC, and carcinoma associated with neuroblastoma are addressed within this review. Tubulocystic carcinoma, thyroid-like follicular carcinoma of kidney, acquired cystic disease-associated RCC, and clear cell papillary RCC are also described. Finally, candidate entities, including RCC with t(6;11) translocation, hybrid oncocytoma/chromophobe RCC, hereditary leiomyomatosis and RCC syndrome, and renal angiomyoadenomatous tumor are reviewed. Knowledge of these new entities is important for diagnosis, treatment and subsequent prognosis. This review provides a targeted summary of new developments in RCC.
文摘During the Sino\|American Expedition to Mt. Qomolangma in May 1997, a 41m ice core was recovered from an elevation of 6500m from the northern branch firn basin of the Far East Rongbuk Glacier in Mt. Everest. The ice core was dated down to 1814 by counting δ 18 O peaks and referring to the variations of β activity and major ion concentrations. The average annual accumulation is 224mm (ice equivalent). Five cold periods and five warm periods have been reconstructed from the ice core for the last 200 years and the general tendency of climatic change is warming, which is agree with the temperature change in the Northern Hemisphere. Also the climatic records in Far East Rongbuk ice core has good agreement with that in the Guliya ice core. This indicates that the climatic changes are consistent in the northwestern and southern Qinghai—Tibetan Plateau, and the ranges of climatic changes are larger in southern Plateau than that in northwestern Plateau. Though the δ 18 O variations has some negatively correlation with precipitation amount for short time scale, these do not effect δ 18 O changes reflecting temperature for long time scale.
基金Supported by the National Natural Science Foundation of China under Grant Nos 11674064 and 11474059the National Key Research and Development Program of China under Grant No 2016YFA0300700
文摘The recently synthesized first 4d transition-metal oxide-hydride LaSr3NiRuO4H4 with the unusual high H:O ratio surprisingly displays no magnetic order down to 1.8 K. This is in sharp contrast to the similar unusual low-valent Ni^+-Ru^2+ layered oxide LaSrNiRuO4 which has a rather high ferromagnetic(FM) ordering Curie temperature TC^250 K. Using density functional calculations with the aid of crystal field level diagrams and superexchange pictures, we find that the contrasting magnetism is due to the distinct spin-orbital states of the Ru^2+ions(in addition to the common Ni+S = 1/2 state but with a different orbital state): the Ru^2+S = 0 state in LaSr3NiRuO4H4, but the Ru^2+S= 1 state in LaSrNiRuO4. The Ru^2+S = 0 state has the(xy)^2(xz, yz)^4 occupation due to the RuH4O2 octahedral coordination, and then the nonmagnetic Ru2+ions dilute the S= 1/2 Ni^+ sublattice which consequently has a very weak antiferromagnetic superexchange and thus accounts for the presence of no magnetic order down to 1.8 K in LaSr3NiRuO4H4. In strong contrast, the Ru^2+S = 1 state in LaSrNiRuO4 has the(3z^2-r^2)^2(xz, yz)^3(xy)^1 occupation due to the planar square RuO4 coordination, and then the multi-orbital FM superexchange between the S= 1/2 Ni^+ and S= 1 Ru^2+ions gives rise to the high TC in LaSrNiRuO4. This work highlights the importance of spin-orbital states in determining the distinct magnetism.
文摘Based on fault geometric features,composite pattern,faulting land-forms and seismic data,this paper discussed the activity behavior along the northern segment of the Anninghe fault(from Xichang to Shimian)since the Late Pleistocene.The fault can be divided into three active segments by discrepancies of their activity:the segment from Xichang to Mianning,the segment from Mianning to Zimakua,and the segment from Zimakua to Tianwan.The southern segment has the background of occurrence of great earthquakes,but the middle and the northern segments can generate strong and moderate events respectively.According to the features of quartz from fault gouges by scanning electron microscopy(SEM),this paper discussed the movement features along the fault and indicated the stick-slipping feature on the segment from Xichang to Zimakua,the creeping feature on the segment from Jiziping to Tianwan and the transitional feature on the segment in between.
文摘Cassava is a multi-purpose crop for food, feed and industrial raw materi- als (starch, modified starch and ethanol fuel). Cassava leaf, an important by-product of cassava industry, is rich in protein, minerals and flavonoids. This article reviews the utilization of cassava leaf in the production of food, animal feed and antioxidants in recent years, analyzes the effects of anti-nutritional factors and extraction of an- tioxidative flavonoids on the utilization of cassava leaf, finally puts forward the main problems in the utilization of cassava leaf, to provide a theoretical basis for the ba- sic research of cassava leaf.
基金Project(51274250)supported by the National Natural Science Foundation of ChinaProject(2012BAK09B02-05)supported by the National Key Technology R&D Program during the 12th Five-year Plan of China
文摘An integration processing system of three-dimensional laser scanning information visualization in goaf was developed. It is provided with multiple functions, such as laser scanning information management for goaf, cloud data de-noising optimization, construction, display and operation of three-dimensional model, model editing, profile generation, calculation of goaf volume and roof area, Boolean calculation among models and interaction with the third party soft ware. Concerning this system with a concise interface, plentiful data input/output interfaces, it is featured with high integration, simple and convenient operations of applications. According to practice, in addition to being well-adapted, this system is favorably reliable and stable.
文摘Rare earth market changes the upward trend recently and began to shock. Price of didymium oxide has fallen from the previous high of 510,000 yuan/ton to 460,000 yuan/ton on Sep. 28. Besides the rational revise of the former price surging, the other reason for the price drop is the slack demand from downstream industries. However, the rare earth groups began cease production to guarantee the market price recently. This is definitely good news for it can ease the oversupply recently. But, whether rare earth price can be backed is finally decided by the demand from downstream industries.