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Red cell distribution width/platelet ratio estimates the 3-year risk of decompensation in Metabolic Dysfunction-Associated Steatotic Liver Disease-induced cirrhosis
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作者 Marcello Dallio Mario Romeo +8 位作者 Paolo Vaia Salvatore Auletta Simone Mammone Marina Cipullo Luigi Sapio Angela Ragone Marco Niosi Silvio Naviglio Alessandro Federico 《World Journal of Gastroenterology》 SCIE CAS 2024年第7期685-704,共20页
BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic event.Based on the first decompensation event(DE),the transition to deco... BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic event.Based on the first decompensation event(DE),the transition to decompensated advanced chronic liver disease(dACLD)can occur through two modalities referred to as acute decompensation(AD)and non-AD(NAD),respectively.Clinically Significant Portal Hypertension(CSPH)is considered the strongest predictor of decompensation in these patients.However,due to its invasiveness and costs,CSPH is almost never evaluated in clinical practice.Therefore,recognizing noninvasively predicting tools still have more appeal across healthcare systems.The red cell distribution width to platelet ratio(RPR)has been reported to be an indicator of hepatic fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD).However,its predictive role for the decompensation has never been explored.AIM In this observational study,we investigated the clinical usage of RPR in predicting DEs in MASLD-related cACLD patients.METHODS Fourty controls and 150 MASLD-cACLD patients were consecutively enrolled and followed up(FUP)semiannually for 3 years.At baseline,biochemical,clinical,and Liver Stiffness Measurement(LSM),Child-Pugh(CP),Model for End-Stage Liver Disease(MELD),aspartate aminotransferase/platelet count ratio index(APRI),Fibrosis-4(FIB-4),Albumin-Bilirubin(ALBI),ALBI-FIB-4,and RPR were collected.During FUP,DEs(timing and modaities)were recorded.CSPH was assessed at the baseline and on DE occurrence according to the available Clinical Practice Guidelines.RESULTS Of 150 MASLD-related cACLD patients,43(28.6%)progressed to dACLD at a median time of 28.9 months(29 NAD and 14 AD).Baseline RPR values were significantly higher in cACLD in comparison to controls,as well as MELD,CP,APRI,FIB-4,ALBI,ALBI-FIB-4,and LSM in dACLD-progressing compared to cACLD individuals[all P<0.0001,except for FIB-4(P:0.007)and ALBI(P:0.011)].Receiving operator curve analysis revealed RPR>0.472 and>0.894 as the best cut-offs in the prediction respectively of 3-year first DE,as well as its superiority compared to the other non-invasive tools examined.RPR(P:0.02)and the presence of baseline-CSPH(P:0.04)were significantly and independently associated with the DE.Patients presenting baseline-CSPH and RPR>0.472 showed higher risk of decompensation(P:0.0023).CONCLUSION Altogether these findings suggest the RPR as a valid and potentially applicable non-invasive tool in the prediction of timing and modalities of decompensation in MASLD-related cACLD patients. 展开更多
关键词 Liver cirrhosis red blood cell distribution width red blood cell distribution width to platelet ratio Translational Medicine Prognostic biomarker
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Enhancing predictive accuracy in hypertriglyceridemia-induced acute pancreatitis:Role of red cell distribution width and prospective studies
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作者 Shi-Yan Zhang 《World Journal of Clinical Cases》 SCIE 2024年第20期4452-4454,共3页
This letter addresses the study titled“Red cell distribution width:A predictor of the severity of hypertriglyceridemia-induced acute pancreatitis”by Lv et al published in the World Journal of Experimental Medicine.T... This letter addresses the study titled“Red cell distribution width:A predictor of the severity of hypertriglyceridemia-induced acute pancreatitis”by Lv et al published in the World Journal of Experimental Medicine.The study offers a valuable analysis of red cell distribution width(RDW)as a predictive marker for persistent organ failure in patients with hypertriglyceridemia-induced acute pancreatitis.The study results suggest that RDW,combined with the Bedside Index for Severity in Acute Pancreatitis score,could enhance the predictive accuracy for severe outcomes.Further investigation into the role of RDW in different severities of acute pancreatitis is recommended.Additionally,the need for large-scale and multicenter prospective studies to validate these findings is emphasized. 展开更多
关键词 red cell distribution width Hypertriglyceridemia-induced acute pancreatitis Persistent organ failure Predictive marker Letter to the Editor COMMENTARY
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A Workable Solution for Reducing the Large Number of Vehicle and Pedestrian Accidents Occurring on a Yellow Light
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作者 Pranav Gupta Silki Arora 《Journal of Transportation Technologies》 2024年第1期82-87,共6页
Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada... Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada, during 2019, the National Collision Database shows that 28% of traffic fatalities and 42% of serious injuries occurred at intersections. Likewise, the U.S. National Highway Traffic Administration (NHTSA) found that about 40% of the estimated 5,811,000 accidents in the U.S. during the year studied were intersection-related crashes. In fact, a major survey by the car insurance industry found that nearly 85% of drivers could not identify the correct action to take when approaching a yellow traffic light at an intersection. One major reason for these accidents is the “yellow light dilemma,” the ambiguous situation where a driver should stop or proceed forward when unexpectedly faced with a yellow light. This situation is even further exacerbated by the tendency of aggressive drivers to inappropriately speed up on the yellow just to get through the traffic light. A survey of Canadian drivers conducted by the Traffic Injury Research Foundation found that 9% of drivers admitted to speeding up to get through a traffic light. Another reason for these accidents is the increased danger of making a left-hand turn on yellow. According to the National Highway Traffic Safety Association (NHTSA), left turns occur in approximately 22.2% of collisions—as opposed to just 1.2% for right turns. Moreover, a study by CNN found left turns are three times as likely to kill pedestrians than right turns. The reason left turns are so much more likely to cause an accident is because they take a driver against traffic and in the path of oncoming cars. Additionally, most of these left turns occur at the driver’s discretion—as opposed to the distressingly brief left-hand arrow at busy intersections. Drive Safe Now proposes a workable solution for reducing the number of accidents occurring during a yellow light at intersections. We believe this fairly simple solution will save lives, prevent injuries, reduce damage to public and private property, and decrease insurance costs. 展开更多
关键词 Traffic Accidents Yellow Light Traffic Light Signals INTERSECTION Crashes Collision Traffic Fatalities Traffic Injuries Vehicles SAFETY Speed Limit Driving Pedestrians Bicyclists MOTORCYCLISTS Caution Line Yellow Light Dilemma Left Hand Turn on Yellow Distance Smart Road Technology Signs Signage Autonomous Vehicles AVs Road Safety IoT Internet of Things Infrastructure Accident reduction Driving Habits Stop Line red Light Jumping Pedestrian Safety Caution Light Stopping at Intersection Safety at Intersections
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Integration of Red Aesthetic Education into Kindergarten and its Practical Paths
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作者 Tingting Wang 《Journal of Contemporary Educational Research》 2024年第3期205-210,共6页
Red culture has important educational value.The integration of red aesthetics into the kindergarten provides strong support for children to establish correct values and historical views in the multi-cultural environme... Red culture has important educational value.The integration of red aesthetics into the kindergarten provides strong support for children to establish correct values and historical views in the multi-cultural environment,and cultivate their creativity and aesthetic consciousness.Red aesthetic education activities should pay attention to the real embodiment of children’s subjectivity and the deep integration of application and practice.Practical paths of red aesthetic education in kindergarten include art activities,multi-field penetration,traditional festivals,and red aesthetic education environment infiltration. 展开更多
关键词 red culture red aesthetic education KINDERGARTEN
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The protective effect of cyclodextrin on the color quality and stability of Cabernet Sauvignon red wine 被引量:1
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作者 Caiyun Liu Lulu Wu +2 位作者 Shuyue Fan Yongsheng Tao Yunkui Li 《Journal of Integrative Agriculture》 SCIE CSCD 2024年第1期310-323,共14页
The impact of cyclodextrins(CDs)on wine quality and stability remains largely unknown.This study systematically assessed the protective effect of the post-fermentation addition of CDs on color stability of red wine fr... The impact of cyclodextrins(CDs)on wine quality and stability remains largely unknown.This study systematically assessed the protective effect of the post-fermentation addition of CDs on color stability of red wine from the viewpoints of color characteristics,copigmentation and phenolic profiles.The grey relational analysis(GRA)and principal component analysis(PCA)methods were employed to dissect the key effective determinants related to color quality.The addition of CDs induced a significant hyperchromic effect of 8.19-25.40%,a significant bathochromic effect and an enhancement of the color intensity.Furthermore,the evolution of anthocyanin forms and the content of monomeric anthocyanins revealed that β-CD is a superior favorable cofactor during wine aging,but for long-term aging,2-HP-β-CD and 2-HP-γ-CD are more beneficial in promoting the formation of polymerized anthocyanins and color stability.This work provides an important reference for the use of CDs to enhance the color quality and stability of red wines. 展开更多
关键词 cyclodextrins color properties copigmentation Helan Mountain’s East Foothill red wine aging
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外源6-BA对小苍兰‘Red Lion’生长及花期调控的影响
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作者 李雪茹 穆红梅 +1 位作者 罗亚桃 文莹莹 《山东农业科学》 北大核心 2024年第4期66-71,共6页
本试验以小苍兰品种‘Red Lion’为材料,研究喷施不同浓度6-BA(25、50、100 mg/L和200 mg/L)对小苍兰生长、生理生化特性及花期的影响,以期为小苍兰花期调控和切花栽培提供技术支持。结果表明:喷施适当浓度的6-BA有利于延长小苍兰‘Red ... 本试验以小苍兰品种‘Red Lion’为材料,研究喷施不同浓度6-BA(25、50、100 mg/L和200 mg/L)对小苍兰生长、生理生化特性及花期的影响,以期为小苍兰花期调控和切花栽培提供技术支持。结果表明:喷施适当浓度的6-BA有利于延长小苍兰‘Red Lion’花期;6-BA浓度为200 mg/L时显著提高小苍兰的花朵直径、花葶长度、小花数、株高、叶片数,较对照花期延长11 d、花朵直径增加50.45%、小花数增加114.89%,同时叶片的丙二醛含量较CK降低34.65%,叶片抗氧化酶(POD、CAT)活性升高,分别比CK提高97.26%和393.24%。综之,喷施适当浓度的6-BA能够显著提高小苍兰‘Red Lion’花朵质量及数量,延长小苍兰花期,其中200 mg/L 6-BA处理效果最佳。 展开更多
关键词 小苍兰‘red Lion’ 6-BA 花期调控 生理生化指标
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5G RedCap技术在电力行业应用的研究
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作者 刘凯 王元杰 +1 位作者 邱学 李正浩 《通信世界》 2024年第12期26-30,共5页
Red Cap(5G轻量化)技术通过精简设备能力和降低复杂度,达到节约成本、降低设备功耗和缩小尺寸等目标,同时保留了5G原生能力,实现了技术和成本的平衡。本文研究了Red Cap的技术特性和相关国家政策,并结合电力行业网络需求,分析Red Cap在... Red Cap(5G轻量化)技术通过精简设备能力和降低复杂度,达到节约成本、降低设备功耗和缩小尺寸等目标,同时保留了5G原生能力,实现了技术和成本的平衡。本文研究了Red Cap的技术特性和相关国家政策,并结合电力行业网络需求,分析Red Cap在电力行业不同场景的应用和部署方案,探讨了Red Cap技术的发展潜力和运营商的部署策略。 展开更多
关键词 电力行业 网络需求 部署策略 设备功耗 发展潜力 部署方案 red 节约成本
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基于Node-RED的基建现场微气象监测与告警系统设计与实现 被引量:1
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作者 李瑞喜 何锐 +1 位作者 辛卫东 张博 《科学技术创新》 2024年第2期119-122,共4页
为了更好地满足输变电工程基建现场应用中对现场环境数据监测与告警的需求,本文设计实现了一种基于Node-RED的基建现场微气象监测与告警系统。该系统通过搭建基于Node-RED的监测预警服务,能够快速完成设备接入,实时监测PM2.5等各项微气... 为了更好地满足输变电工程基建现场应用中对现场环境数据监测与告警的需求,本文设计实现了一种基于Node-RED的基建现场微气象监测与告警系统。该系统通过搭建基于Node-RED的监测预警服务,能够快速完成设备接入,实时监测PM2.5等各项微气象指标,并且能够通过自动执行预设的处置策略就地进行告警或将数据推送至相关平台。该系统可以有效提升基建现场环境监测与告警的效率,在推进电力基建领域的数字化、智能化转型方面具有显著意义。 展开更多
关键词 Node-red 变电工程 基建现场 监测告警
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A green cross-linking method for the preparation of renewable threedimensional graphene sponges for efficient adsorption of Congo red dye
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作者 Zhuang Liu Bo Gao +3 位作者 Haoyuan Han Yuling Li Haiyang Fu Donghui Wei 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第2期84-93,共10页
Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn pollutants.However,their utilization is hindered by high prepar... Graphene-based materials possess significant potential for the treatment of dye wastewater due to their exceptional adsorption properties toward stubborn pollutants.However,their utilization is hindered by high preparation costs,low yields,environmental pollution during synthesis,and challenges in regenerating the adsorbent.This study proposes a novel approach to address these limitations by developing nitrogen-doped three-dimensional(3D)polyvinyl alcohol(PVA)crosslinked graphene sponges(N-PGA)using a cross-linking method with ammonium carbonate.This method offers a relatively mild,environmentally friendly approach.Ammonium carbonate serves as both a reducing and modifying agent,facilitating the formation of the intrinsic structure of N-PGA and acting as a nitrogen source.Meanwhile,PVA is utilized as the cross-linking agent.The results demonstrate that N-PGA exhibits a favorable internal 3D hierarchical porous structure and possesses robust mechanical properties.The measured specific surface area(BET)of N-PGA was as high as406.538 m^(2)·g^(-1),which was favorable for its efficient adsorption of Congo red(CR)dye molecules.At an initial concentration of 50 mg·L^(-1),N-PGA achieved an impressive removal rate of 89.6%and an adsorption capacity of 112 mg·g^(-1)for CR dye.Furthermore,it retained 79%of its initial adsorption capacity after 10 cycles,demonstrating excellent regeneration performance.In summary,the synthesized N-PGA displays remarkable efficacy in the adsorption of CR dye in wastewater,opening up new possibilities for utilizing 3D porous graphene nanomaterials as efficient adsorbents in wastewater treatment. 展开更多
关键词 Green chemistry Graphene sponge Adsorbents ADSORPTION Congo red Regeneration
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Solidification/Stabilization of Chromium in Red Mud-based Geopolymer
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作者 田崇霏 LUO Zhongtao +4 位作者 LIU Lei LIU Xiaohai 张美香 陈萌 HAI Ran 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第4期819-830,共12页
Up to 1.5wt%of Cr(Ⅲ)salts(CrCl_(3),and Cr_(2)O_(3))and Cr(Ⅵ)salts(Na_(2)CrO_(4),and CaCr_(2)O_(7))were incorporated into red mud-based geopolymers,respectively.The solidification/stabilization,compressive strength,a... Up to 1.5wt%of Cr(Ⅲ)salts(CrCl_(3),and Cr_(2)O_(3))and Cr(Ⅵ)salts(Na_(2)CrO_(4),and CaCr_(2)O_(7))were incorporated into red mud-based geopolymers,respectively.The solidification/stabilization,compressive strength,and durability of the Cr-containing geopolymers were investigated.The experimental results indicate that the red mud-based geopolymer could effectively solidify/stabilize different types of Cr salts with solidification/stabilization rates of above 99.61%.Geopolymers are environmentally safe when the dosage of CaCr_(2)O_(7)is≤1.0wt%,or the dosage of CrCl_(3),Cr_(2)O_(3),and Na_(2)CrO_(4)is≤1.5wt%,respectively.The effects of Cr salts on the compressive strength varies with the type and content of Cr salts.The freeze-thaw cycle is more destructive to geopolymer properties than sulfate attack or acid rain erosion.The solidification/stabilization of Cr is mainly attributed to the following reasons:a)The chemical binding of Cr is related to the formation of Cr-containing hydrates(eg,magnesiochromite((Mg,Fe)(Cr,Al)_(2)O_(4)))and doping into N-A-S-H gel and C-A-S-H gel framework;b)The physical effect is related to the encapsulation by the hydration products(e g,N-A-S-H gel and C-A-S-H gel).This study provides a reference for the treatment of hazardous Cr-containing wastes by solid waste-based geopolymers. 展开更多
关键词 CHROMIUM SOLIDIFICATION/STABILIZATION GEOPOLYMER red mud DURABILITY
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Red/ET同源重组介导的基因克隆载体pBACS的构建、鉴定与应用
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作者 侯少阳 李岚芳 +5 位作者 杜丽霞 孙林慧 李典 禚惠荣 姜莉莉 张大虎 《沈阳药科大学学报》 CAS CSCD 2024年第5期590-597,共8页
目的通过Red/ET同源重组技术构建pBACS基因克隆及测序质粒载体。方法以质粒pBAC2015、pET28a为模板设计四对引物,PCR扩增得到四段彼此间有50 bp同源区域的基因片段,分别命名为bac-sop、bac-ori、bac-kan和bac-T7。利用Red/ET同源重组技... 目的通过Red/ET同源重组技术构建pBACS基因克隆及测序质粒载体。方法以质粒pBAC2015、pET28a为模板设计四对引物,PCR扩增得到四段彼此间有50 bp同源区域的基因片段,分别命名为bac-sop、bac-ori、bac-kan和bac-T7。利用Red/ET同源重组技术,将四段基因片段电转至E.coli GB05-dir感受态中进行线线重组。经酶切、测序验证阳性克隆质粒。此外,对重组质粒pBACS进行稳定性鉴定;利用pBACS分别进行细菌16S rDNA和真菌ITS基因克隆和基因测序。结果酶切和测序的验证结果显示,质粒的大小、元件方向及序列正确;pBACS具有较强的稳定性,适用于作为基因工程的克隆载体;可高效用于细菌16S rDNA和真菌ITS序列的克隆,阳性率为100%。结论成功利用Red/ET技术构建克隆载体pBACS,质粒载体具有稳定性强、重组效率高的特点,在基因克隆和基因测序等方面具有良好的应用潜力。 展开更多
关键词 pBACS 克隆 red/ET技术 同源重组
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JrATHB-12 mediates JrMYB113 and JrMYB27 to control the anthocyanin levels in different types of red walnut
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作者 Haifeng Xu Guifang Wang +7 位作者 Xinying Ji Kun Xiang Tao Wang Meiyong Zhang Guangning Shen Rui Zhang Junpei Zhang Xin Chen 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2024年第8期2649-2661,共13页
Red walnut has broad market prospects because it is richer in anthocyanins than ordinary walnut.However,the mechanism driving anthocyanin biosynthesis in red walnut is still unknown.We studied two types of red walnut,... Red walnut has broad market prospects because it is richer in anthocyanins than ordinary walnut.However,the mechanism driving anthocyanin biosynthesis in red walnut is still unknown.We studied two types of red walnut,called red walnut 1(R1),with a red pericarp and seed coat,and red walnut 2(R2),with a red seed coat only.R1 mostly contained cyanidin-3-O-galactoside,while R2 contained a various amounts of cyanidin-3-Ogalactoside,cyanidin-3-O-arabinoside,and cyanidin-3-O-glucoside.The LDOX-2(LOC109007163)and LDOX-3(LOC109010746)genes,which encode leucoanthocyanidin dioxygenase/anthocyanidin synthase(LDOX/ANS),were preliminarily indicated as the crucial genes for anthocyanin biosynthesis in R1 and R2,respectively.The MYB differential genes analysis showed that MYB27 and MYB113 are specifically expressed in the red parts of R1 and R2,respectively,and they are regarded as candidate regulatory genes.Ectopic expression in Arabidopsis and transient injection in walnut showed that both MYB27 and MYB113 were located in the nucleus and promoted anthocyanin accumulation,while MYB27 promoted the expression of LDOX-2,and MYB113 promoted the expression of LDOX-3and UAGT-3.Yeast one-hybrid and electrophoretic mobility shift assays showed that MYB27 could only bind to the LDOX-2 promoter,while MYB113 could bind to the promoters of both LDOX-3 and UAGT-3.In addition,we also identified an HD-Zip transcription factor,ATHB-12,which is specifically expressed in the pericarp.After silencing the expression of ATHB-12,the R2 pericarp turned red,and MYB113 expression increased.Further experiments showed that ATHB-12 could specifically interact with MYB113 and bind to its promoter.This suggests that MYB27controls R1 coloration by regulating LDOX-2,while MYB113 controls R2 coloration by regulating LDOX-3 and UAGT-3,but ATHB-12 can specifically bind to and inhibit the MYB113 of the R2 pericarp so that it becomes unpigmented.This study reveals the anthocyanin biosynthetic mechanisms in two different types of red walnut and provides a scientific basis for the selection and breeding of red walnut varieties. 展开更多
关键词 JrATHB-12 JrMYB113 JrMYB27 red walnut anthocyanin biosynthesis
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Evolution model and failure mechanisms of rainfall-induced cracked red clay slopes:insights from Xinshao County,China
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作者 JIAO Weizhi ZHANG Ming +4 位作者 LI Peng XIE Junjin PANG Haisong LIU Fuxing YANG Long 《Journal of Mountain Science》 SCIE CSCD 2024年第3期867-881,共15页
Red clay landslides are widely distributed worldwide,resulting in severe loss of life and property.Although rainfall-induced red clay slopes have received extensive attention,the role of cracks in the evolutionary pro... Red clay landslides are widely distributed worldwide,resulting in severe loss of life and property.Although rainfall-induced red clay slopes have received extensive attention,the role of cracks in the evolutionary process of red clay slopes and their connection to failure mechanisms is still poorly understood.A comprehensive approach integrating field investigation,laboratory tests,and numerical simulations was conducted to study the 168 red clay landslides in Xinshao County,China.The results show that red clay is prone to forming cracks at high moisture content due to its low swelling and high shrinkage properties.The failure mode of red clay slopes can be summarized in three stages:crack generation,slope excavation,and slope failure.Furthermore,the retrospective analysis and numerical simulations of the typical landslide in Guanchong indicated that intense rainfall primarily impacts the shallow layer of soil within approximately 0.5 m on the intact slope.However,cracks change the pattern of rainfall infiltration in the slope.Rainwater infiltrates rapidly through the preferential channels induced by the cracks rather than uniformly and slowly from the slope surface.This results in a significant increase in both the depth of infiltration and the saturated zone area of the cracked slope,reaching 3.8 m and 36.2 m^(2),respectively.Consequently,the factor of safety of the slope decreases by 13.4%compared to the intact slope,ultimately triggering landslides.This study can provide valuable insights into understanding the failure mechanisms of red clay slopes in China and other regions with similar geological settings. 展开更多
关键词 red clay slopes Cracks Preferential flow Failure mechanism
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Red cell distribution width-to-albumin ratio is a simple promising prognostic marker in acute cholangitis requiring biliary drainage
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作者 Fatih Acehan Hüseyin Camli +4 位作者 Cagdas Kalkan Mesut Tez Burak Furkan Demir Emin Altiparmak Ihsan Ates 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2024年第5期487-494,共8页
Background: It is crucial to assess the severity of acute cholangitis(AC). There are currently several prognostic markers. However, the accuracies of these markers are not satisfied. The present study aimed to investi... Background: It is crucial to assess the severity of acute cholangitis(AC). There are currently several prognostic markers. However, the accuracies of these markers are not satisfied. The present study aimed to investigate the predictive value of the red cell distribution width(RDW)-to-albumin ratio(RAR) for the prognosis of AC. Methods: We retrospectively evaluated consecutive patients diagnosed with AC between May 2019 and March 2022. RAR was calculated, and its predictive ability for in-hospital mortality, intensive care unit(ICU) admission, bacteremia, and the length of hospitalization were analyzed. Results: Out of 438 patients, 34(7.8%) died. Multivariate analysis showed that malignant etiology [odds ratio(OR) = 4.816, 95% confidence interval(CI): 1.936-11.980], creatinine(OR = 1.649, 95% CI: 1.095-2.484), and RAR(OR = 2.064, 95% CI: 1.494-2.851) were independent risk factors for mortality. When adjusted for relevant covariates, including age, sex, malignant etiology, Tokyo severity grading(TSG), Charlson comorbidity index, and creatinine, RAR significantly predicted mortality(adjusted OR = 1.833, 95% CI: 1.280-2.624). When the cut-off of RAR was set to 3.8, its sensitivity and specificity for mortality were 94.1% and 56.7%, respectively. Patients with an RAR of > 3.8 had a 20.9-fold(OR = 20.9, 95% CI: 4.9-88.6) greater risk of mortality than the remaining patients. The area under the curve value of RAR for mortality was 0.835(95% CI: 0.770-0.901), which was significantly higher than that of TSG and the other prognostic markers, such as C-reactive protein-to-albumin ratio, and procalcitonin-to-albumin ratio. Lastly, RAR was not inferior to TSG in predicting ICU admission, bacteremia, and the length of hospitalization. Conclusions: RAR successfully predicted the in-hospital mortality, ICU admission, bacteremia, and the length of hospitalization of patients with AC, especially in-hospital mortality. RAR is a promising marker that is more convenient than TSG and other prognostic markers for predicting the prognosis of patients with AC. 展开更多
关键词 Acute cholangitis ALBUMIN Biliary drainage MORTALITY red blood cell distribution width-to-albumin ratio
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基于Node-red的云端智能生产线控制系统设计与实现
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作者 陈玄烨 张鑫 +2 位作者 张景翔 文世华 李红利 《山东工业技术》 2024年第3期58-62,共5页
针对传统生产线在刚性生产过程中面临的成本过高、远程实施难、兼容性低等关键问题,基于目前中小企业的技术基础相对薄弱,无法将云计算平台、数据存储和处理等设备及技术运用到实际生产中的现状,本文利用西门子S7-1200 PLC作为核心控制... 针对传统生产线在刚性生产过程中面临的成本过高、远程实施难、兼容性低等关键问题,基于目前中小企业的技术基础相对薄弱,无法将云计算平台、数据存储和处理等设备及技术运用到实际生产中的现状,本文利用西门子S7-1200 PLC作为核心控制器,基于Node-red平台设计了成本低、兼容性高的云端智能生产线监控系统,便于实现对于生产线的监视和控制,提高生产效率与产品质量。现场运行表明,该系统运行稳定,满足智能生产线的设计要求,同时具备部署成本低、兼容性高的突出优势。 展开更多
关键词 工业物联网 Node-red 智能生产线 云端控制系统
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RED在修订后的附件九中添加新的原料
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作者 汤玮健(摘译) 《石油炼制与化工》 CAS CSCD 北大核心 2024年第6期23-23,共1页
欧洲生物柴油委员会(EBB)欢迎在欧盟委员会通过的《可再生能源指令》(RED)修订附件九中添加几种新的原料。但在实施之前,仍需进一步澄清新增原料的定义。2024年3月14日,欧盟委员会通过了期待已久的授权法案,修订了RED附件九。该文本大... 欧洲生物柴油委员会(EBB)欢迎在欧盟委员会通过的《可再生能源指令》(RED)修订附件九中添加几种新的原料。但在实施之前,仍需进一步澄清新增原料的定义。2024年3月14日,欧盟委员会通过了期待已久的授权法案,修订了RED附件九。该文本大幅增加了附件中的原料数量,这是欧盟将可再生能源纳入运输部门并促进其实现脱碳的关键一步。 展开更多
关键词 欧盟委员会 可再生能源 附件 red 生物柴油 原料数量 修订
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Analysis of Calcined Red Mud Properties and Related Mortar Performances
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作者 Zhengfan Lyu Yulin Li +2 位作者 Mengmeng Fan Yan Huang Chenguang Li 《Fluid Dynamics & Materials Processing》 EI 2024年第5期901-913,共13页
Red mud(RM)is a low-activity industrial solid waste,and its utilization as a resource is currently a hot topic.In this study,the micro characteristics of red mud at different calcination temperatures were analyzed usi... Red mud(RM)is a low-activity industrial solid waste,and its utilization as a resource is currently a hot topic.In this study,the micro characteristics of red mud at different calcination temperatures were analyzed using X-ray diffraction and scanning electron microscopy.The performance of calcined red mud was determined through mortar strength tests.Results indicate that high-temperature calcination can change the mineral composition and microstructure of red mud,and increase the surface roughness and specific surface area.At the optimal temperature of 700°C,the addition of calcined red mud still leads to a decrease in mortar strength,but its activity index and flexural coefficient increase by 16.2%and 11.9%with respect to uncalcined red mud,reaching values of 0.826 and 0.974,respectively.Compared with the control group,the synergistic activation of calcined red mud with slag can increase the compressive and flexural strength of the mortar by 12.9%and 1.5%,reaching 8.7 and 62.4 MPa,respectively.Correspondingly,the activity index and flexural coefficient of the calcined RM and GGBS(Ground Granulated Blast furnace Slag)mixtures also increase to 1.015 and 1.130,respectively. 展开更多
关键词 red mud SLAG thermal activation synergistic activation mortar test microscopic properties
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Performances of fissured red sandstone after thermal treatment with constant-amplitude and low-cycle impacts
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作者 Yongjun Chen Tubing Yin +3 位作者 P.G.Ranjith Xibing Li Qiang Li Dengdeng Zhuang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第2期561-587,共27页
In the engineering practices,it is increasingly common to encounter fractured rocks perturbed by temperatures and frequent dynamic loads.In this paper,the dynamic behaviors and fracture characteristics of red sandston... In the engineering practices,it is increasingly common to encounter fractured rocks perturbed by temperatures and frequent dynamic loads.In this paper,the dynamic behaviors and fracture characteristics of red sandstone considering temperatures(25℃,200℃,400℃,600℃,and 800℃)and fissure angles(0°,30°,60°,and 90°)were evaluated under constant-amplitude and low-cycle(CALC)impacts actuated by a modified split Hopkinson pressure bar(SHPB)system.Subsequently,fracture morphology and second-order statistics within the grey-level co-occurrence matrix(GLCM)were examined using scanning electron microscopy(SEM).Meanwhile,the deep analysis and discussion of the mechanical response were conducted through the synchronous thermal analyzer(STA)test,numerical simulations,one-dimensional stress wave theory,and material structure.The multiple regression models between response variables and interactive effects of independent variables were established using the response surface method(RSM).The results demonstrate the fatigue strength and life diminish as temperatures rise and increase with increasing fissure angles,while the strain rate exhibits an inverse behavior.Furthermore,the peak stress intensification and strain rate softening observed during CALC impact exhibit greater prominence at increased fissure angles.The failure is dominated by tensile damage with concise evolution paths and intergranular cracks as well as the compressor-crushed zone which may affect the failure mode after 400℃.The second-order statistics of GLCM in SEM images exhibit a considerable dependence on the temperatures.Also,thermal damage dominated by thermal properties controls the material structure and wave impedance and eventually affects the incident wave intensity.The tensile wave reflected from the fissure surface is the inherent mechanism responsible for the angle effect exhibited by the fatigue strength and life.Ultimately,the peak stress intensification and strain rate softening during impact are determined by both the material structure and compaction governed by thermal damage and tensile wave. 展开更多
关键词 red sandstone Temperature FISSURE Constant-amplitude and low-cycle(CALC) impact Fatigue failure Response surface method(RSM)
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Synergistic CO_(2) mineralization using coal fly ash and red mud as a composite system
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作者 Zhenchao Yao Yugao Wang +3 位作者 Jun Shen Yanxia Niu Jiang Feng Yang Xianyong Wei 《International Journal of Coal Science & Technology》 EI CAS CSCD 2024年第3期149-158,共10页
CO_(2) mineralization plays a critical role in the storage and utilization of CO_(2).Coal fly ash(CFA)and red mud(RM)are widely utilized as CO_(2) mineralizers.However,the inert calcium species in CFA limit its carbon... CO_(2) mineralization plays a critical role in the storage and utilization of CO_(2).Coal fly ash(CFA)and red mud(RM)are widely utilized as CO_(2) mineralizers.However,the inert calcium species in CFA limit its carbonation capacity,meanwhile the substantial Ca^(2+)releasing of RM is hindered by a covering layer of calcium carbonate.In this study,CO_(2) mineralization in a composite system of CFA and RM was investigated to enhance the carbonation capacity.Multiple analyzers were employed to characterize the raw materials and resulting mineralization products.The results demonstrated that a synergistic effect existed in the composite system of CFA and RM,resulting in improving CO_(2) mineralization rate and efficiency.The produced calcium carbonate was ectopically attached the surface of CFA in the composite system,thus slowing down its coverage on the surface of RM.This phenomenon facilitated further releasing Ca^(2+)from the internal RM,thereby enhancing CO_(2) mineralization efficiency.Meanwhile,the inclusion of RM significantly improved the alkalinity of the composite system,which not only promoted the dissolution of Ca^(2+)of the inert CaSO_(4)(H_(2)O)_(2) in CFA,but also accelerated CO_(2) mineralization rate.The investigation would be beneficial to CO_(2) mineralization using industrial solid wastes. 展开更多
关键词 CO_(2)mineralization Coal fly ash red mud Synergistic effect
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Predictive value of red blood cell distribution width and hematocrit for short-term outcomes and prognosis in colorectal cancer patients undergoing radical surgery
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作者 Dong Peng Zi-Wei Li +2 位作者 Fei Liu Xu-Rui Liu Chun-Yi Wang 《World Journal of Gastroenterology》 SCIE CAS 2024年第12期1714-1726,共13页
BACKGROUND Previous studies have reported that low hematocrit levels indicate poor survival in patients with ovarian cancer and cervical cancer,the prognostic value of hematocrit for colorectal cancer(CRC)patients has... BACKGROUND Previous studies have reported that low hematocrit levels indicate poor survival in patients with ovarian cancer and cervical cancer,the prognostic value of hematocrit for colorectal cancer(CRC)patients has not been determined.The prognostic value of red blood cell distribution width(RDW)for CRC patients was controversial.AIM To investigate the impact of RDW and hematocrit on the short-term outcomes and long-term prognosis of CRC patients who underwent radical surgery.METHODS Patients who were diagnosed with CRC and underwent radical CRC resection between January 2011 and January 2020 at a single clinical center were included.The short-term outcomes,overall survival(OS)and disease-free survival(DFS)were compared among the different groups.Cox analysis was also conducted to identify independent risk factors for OS and DFS.RESULTS There were 4258 CRC patients who underwent radical surgery included in our study.A total of 1573 patients were in the lower RDW group and 2685 patients were in the higher RDW group.There were 2166 and 2092 patients in the higher hematocrit group and lower hematocrit group,respectively.Patients in the higher RDW group had more intraoperative blood loss(P<0.01)and more overall complications(P<0.01)than did those in the lower RDW group.Similarly,patients in the lower hematocrit group had more intraoperative blood loss(P=0.012),longer hospital stay(P=0.016)and overall complications(P<0.01)than did those in the higher hematocrit group.The higher RDW group had a worse OS and DFS than did the lower RDW group for tumor node metastasis(TNM)stage I(OS,P<0.05;DFS,P=0.001)and stage II(OS,P=0.004;DFS,P=0.01)than the lower RDW group;the lower hematocrit group had worse OS and DFS for TNM stage II(OS,P<0.05;DFS,P=0.001)and stage III(OS,P=0.001;DFS,P=0.001)than did the higher hematocrit group.Preoperative hematocrit was an independent risk factor for OS[P=0.017,hazard ratio(HR)=1.256,95%confidence interval(CI):1.041-1.515]and DFS(P=0.035,HR=1.194,95%CI:1.013-1.408).CONCLUSION A higher preoperative RDW and lower hematocrit were associated with more postoperative complications.However,only hematocrit was an independent risk factor for OS and DFS in CRC patients who underwent radical surgery,while RDW was not. 展开更多
关键词 Colorectal cancer red blood cell distribution width SURVIVAL Short-term outcomes
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