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Scattering of Oblique Surface Waves by the Edge of Small Deformation on a Porous Ocean Bed 被引量:1
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作者 Smrutiranjan Mohapatra 《Journal of Marine Science and Application》 CSCD 2015年第2期156-162,共7页
The scattering of oblique incident surface waves by the edge of a small cylindrical deformation on a porous bed in an ocean of finite depth, is investigated here within the framework of linearized water wave theory. U... The scattering of oblique incident surface waves by the edge of a small cylindrical deformation on a porous bed in an ocean of finite depth, is investigated here within the framework of linearized water wave theory. Using perturbation analysis, the corresponding problem governed by modified Helmholtz equation is reduced to a boundary value problem for the first-order correction of the potential function. The first-order potential and, hence, the reflection and transmission coefficients are obtained by a method based on Green's integral theorem with the introduction of appropriate Green's function. Consideration of a patch of sinusoidal ripples shows that when the quotient of twice the component of the incident field wave number along x-direction and the ripple wave number approaches one, the theory predicts a resonant interaction between the bed and the free-surface, and the reflection coefficient becomes a multiple of the number of ripples. Again, for small angles of incidence, the reflected energy is more as compared to the other angles of incidence. It is also observed that the reflected energy is somewhat sensitive to the changes in the porosity of the ocean bed. From the derived results, the solutions for problems with impermeable ocean bed can be obtained as particular cases. 展开更多
关键词 oblique waves bottom deformation porous bed Green's function perturbation technique reflection coefficient transmission coefficient scattering
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Scattering of Oblique Surface Water Waves by Thin Vertical Barrier Over Undulating Bed Topography
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作者 A. Choudhary S. C. Martha 《Journal of Marine Science and Application》 CSCD 2017年第2期190-198,共9页
The present study deals with the scattering of oblique surface water waves by small undulation on the bottom in the presence of a thin vertical barrier. Here, three different configurations of vertical barriers are in... The present study deals with the scattering of oblique surface water waves by small undulation on the bottom in the presence of a thin vertical barrier. Here, three different configurations of vertical barriers are investigated. Perturbation analysis is employed to determine the physical quantities, namely, the reflection and transmission coefficients. In this analysis, many different Boundary Value Problems (BVPs) are obtained out of which the first two bvps are considered. The zeroth order bvp is solved with the aid of eigenfunction expansion method. The first order reflection and transmission coefficients are derived in terms of the integrals by the method of the Green's integral theorem. The variation of these coefficients is plotted and analyzed for different physical parameters. Furthermore, the energy balance relation, an important relation in the study of water wave scattering, is derived and checked for assuring the correctness of the numerical results for the present problem. 展开更多
关键词 OBLIQUE wave scattering bottom UNDULATION VERTICAL BARRIER EIGENFUNCTION expansion Green’s integral theorem reflection and transmission coefficients
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Scattering of water waves by thin vertical plate submerged below ice-cover surface
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作者 P.MAITI P.RAKSHIT S.BANERJEA 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI 2011年第5期635-644,共10页
The present paper is concerned with scattering of water waves from a vertical plate, modeled as an elastic plate, submerged in deep water covered with a thin uniform sheet of ice. The problem is formulated in terms of... The present paper is concerned with scattering of water waves from a vertical plate, modeled as an elastic plate, submerged in deep water covered with a thin uniform sheet of ice. The problem is formulated in terms of a hypersingular integral equation by a suitable application of Green's integral theorem in terms of difference of potential functicns across the barrier. This integral equation is solved by a collocation method using a finite series involving Chebyshev polynomials. Reflection and transmission coefficients are obtained numerically and presented graphically for various values of the wave number and ice-cover parameter. 展开更多
关键词 scattering problem ice-cover surface hypersingular integral equation Green's integral theorem reflection and transmission coefficients
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A Note on the Solution of Water Wave Scattering Problem Involving Small Deformation on a Porous Channel-Bed
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作者 S.Mohapatra M.R.Sarangi 《Journal of Marine Science and Application》 CSCD 2017年第1期10-19,共10页
The solution of water wave scattering problem involving small deformation on a porous bed in a channel, where the upper surface is bounded above by an infinitely extent rigid horizontal surface, is studied here within... The solution of water wave scattering problem involving small deformation on a porous bed in a channel, where the upper surface is bounded above by an infinitely extent rigid horizontal surface, is studied here within the framework of linearized water wave theory. In such a situation, there exists only one mode of waves propagating on the porous surface. A simplified perturbation analysis, involving a small parameter ε (≤1) , which measures the smallness of the deformation, is employed to reduce the governing Boundary Value Problem (BVP) to a simpler BVP for the first-order correction of the potential function. The first-order potential function and, hence, the first-order reflection and transmission coefficients are obtained by the method based on Fourier transform technique as well as Green's integral theorem with the introduction of appropriate Green's function. Two special examples of bottom deformation: the exponentially damped deformation and the sinusoidal ripple bed, are considered to validate the results. For the particular example of a patch of sinusoidal ripples, the resonant interaction between the bed and the upper surface of the fluid is attained in the neighborhood of a singularity, when the ripples wavenumbers of the bottom deformation become approximately twice the components of the incident field wavenumber along the positive x -direction. Also, the main advantage of the present study is that the results for the values of reflection and transmission coefficients are found to satisfy the energy-balance relation almost accurately. 展开更多
关键词 Porous bed bottom deformation perturbation analysis Fourier Transform Green's function reflection coefficient transmission coefficient energy identity water wave scattering
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生物组织光学参数:优化散射系数(μ′_s)的实时在位测定 被引量:14
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作者 钱志余 陈仁文 +2 位作者 顾月清 Cole A.Giller 刘汉莉 《南京航空航天大学学报》 EI CAS CSCD 北大核心 2004年第3期369-372,共4页
利用了一套特殊设计光纤探头组成的稳定态光纤光谱仪测试生物组织的光学参数 ,从悬乳液 ( Intralipid)与模拟胶 ( Phantom)实验推导出优化散射系数 ( Reduced scattering coefficient:μ′s)近红外谱测量经验公式。测量反射系数就可以... 利用了一套特殊设计光纤探头组成的稳定态光纤光谱仪测试生物组织的光学参数 ,从悬乳液 ( Intralipid)与模拟胶 ( Phantom)实验推导出优化散射系数 ( Reduced scattering coefficient:μ′s)近红外谱测量经验公式。测量反射系数就可以计算出优化散射系数谱。计算结果用模拟胶作了验证 ,并对大鼠脑组织μ′s 进行了实时在位测量 ,从而得到了一种 μ′s 展开更多
关键词 反射系数 优化散射系数 模拟胶 光谱仪 组织
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基于功能近红外光谱技术(fNIRs)的帕金森病大鼠模型脑组织特性研究 被引量:6
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作者 胡光霞 钱志余 +2 位作者 孙涛 杨天明 王文宏 《光谱学与光谱分析》 SCIE EI CAS CSCD 北大核心 2010年第9期2360-2364,共5页
利用功能近红外光谱技术(functionality near infrared spectroscopy,fNIRs)探索帕金森病(parkin-son′s disease,PD)大鼠模型的脑组织功能特性。通过小动物磁共振(magnetic resonance imaging,MRI)和电子计算机断层扫描(computed tomog... 利用功能近红外光谱技术(functionality near infrared spectroscopy,fNIRs)探索帕金森病(parkin-son′s disease,PD)大鼠模型的脑组织功能特性。通过小动物磁共振(magnetic resonance imaging,MRI)和电子计算机断层扫描(computed tomography,CT)对PD大鼠模型进行影像学研究,用fNIRs系统测试大鼠模型脑组织纹状体特征参数。实验结果表明,PD大鼠脑部没有明显的形态结构变化;优化散射系数(reducedscattering coefficient:μ′s)、脑血容量(cerebral blood volume:CBV)在PD大鼠的纹状体部与对照组间存在显著的差别;fNIRs测量参数(μ′s、CBV)与CT灌注(CTP)测定参数[CBF(cerebral blood flow),CBV]之间存在相关性。这些结果表明fNIRs可以作为PD研究的重要参考手段。 展开更多
关键词 功能近红外光谱 优化散射系数(μ′s) 脑血容量 脑组织特性
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近红外光谱(NIRS)技术的大鼠胶质瘤活体在位检测研究 被引量:6
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作者 郭丽娜 钱志余 +2 位作者 李宽正 戴丽娟 何亮 《量子电子学报》 CAS CSCD 北大核心 2008年第4期483-488,共6页
采用一套专门设计的由微创光纤探头组成的光纤光谱仪生物组织光学参数测试系统,实时在位地获取C6胶质瘤大鼠脑组织的近红外光学参数,探讨以此为指标判别肿瘤基本信息、辅助临床诊断的可能性。利用该测试系统对患有C6胶质瘤的大鼠脑部肿... 采用一套专门设计的由微创光纤探头组成的光纤光谱仪生物组织光学参数测试系统,实时在位地获取C6胶质瘤大鼠脑组织的近红外光学参数,探讨以此为指标判别肿瘤基本信息、辅助临床诊断的可能性。利用该测试系统对患有C6胶质瘤的大鼠脑部肿瘤侧和正常侧进行近红外光谱检测。实验结果表明:优化散射系数和血氧饱和度可反映肿瘤位置及病理分化程度信息。证实近红外微探针技术对胶质瘤定性诊断是可行的,为近红外光谱技术临床应用打下基础。 展开更多
关键词 生物医学光子学 C6胶质瘤 近红外光谱技术 血氧饱和度 优化散射系数
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实时在位测定大鼠脑组织优化散射系数(μ's)的技术研究 被引量:12
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作者 钱志余 顾月清 刘汉莉 《中国医学物理学杂志》 CSCD 2005年第2期463-465,共3页
目的:测试大鼠活体脑组织优化散射系数(reducedscatteringcoefficient:μ’s)。材料与方法:利用稳定态光纤光谱仪对大鼠脑组织的优化散射系数进行了系统研究,基本方法是利用悬乳液(Intralipid)和模拟胶(Phantom)模拟实验的μ’s经验公... 目的:测试大鼠活体脑组织优化散射系数(reducedscatteringcoefficient:μ’s)。材料与方法:利用稳定态光纤光谱仪对大鼠脑组织的优化散射系数进行了系统研究,基本方法是利用悬乳液(Intralipid)和模拟胶(Phantom)模拟实验的μ’s经验公式得到大鼠脑组织在近红外波段(650nm~850nm)μ’s谱。结果:获得了大鼠脑白质和脑灰质的优化散射系数活体在位测量经验公式。结论:首次获得活体在位大鼠脑组织μ’s谱规律。 展开更多
关键词 脑白质 吸收系数 优化散射系数 光谱仪
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多次各向异性散射模式对S波能量密度包络曲线的影响 被引量:2
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作者 景月岭 Yuehua Zeng +2 位作者 林皋 Genda Chen 李建波 《地球物理学报》 SCIE EI CAS CSCD 北大核心 2012年第6期1993-2003,共11页
在多次各向异性散射理论的基础上,本文重新推导了方向性散射系数的球函数展开式.引入特征时间的概念,来定义震源处初始地震波脉冲宽度,并在地震波能量密度积分方程中引入任意给定频率的初始脉冲能量谱密度的解析表达.通过离散波数方法... 在多次各向异性散射理论的基础上,本文重新推导了方向性散射系数的球函数展开式.引入特征时间的概念,来定义震源处初始地震波脉冲宽度,并在地震波能量密度积分方程中引入任意给定频率的初始脉冲能量谱密度的解析表达.通过离散波数方法求解了修正的地震波能量密度积分方程.基于积分方程的数值解,研究了不同散射模式对S波能量密度包络曲线的影响.计算结果表明:随着震源距的增加,在S波到时之后,多次各向异性散射模式与多次各向同性散射模式合成的能量密度包络差异逐渐增大.其中通过多次前散射模式,我们可以得到不同震源距的尾波能量密度包络的同一衰减趋势,以及S波能量密度包络随着震源距的增加而出现的展宽现象.最后,利用美国内华达州Wells地震余震的台站记录验证了多次前散射模式的实用性与有效性. 展开更多
关键词 多次各向异性散射 s波能量密度包络 方向性散射系数 包络展宽 尾波 同一衰减 能量传输理论
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OPTICAL PROPERTIES OF SKIN,SUBCUTANEOUS,AND MUSCLE TISSUES:A REVIEW 被引量:18
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作者 ALEXEY N.BASHKATOV ELINA A.GENINA VALERY V.TUCHIN 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2011年第1期9-38,共30页
The development of optical methods in modern medicine in the areas of diagnostics,therapy,and surgery has stimulated the investigation of optical properties of various biological tissues,since the efficacy of laser tr... The development of optical methods in modern medicine in the areas of diagnostics,therapy,and surgery has stimulated the investigation of optical properties of various biological tissues,since the efficacy of laser treatment depends on the photon propagation and fluence rate distribution within irradiated tissues.In this work,an overview of published absorption and scattering properties of skin and subcutaneous tissues measured in wide wavelength range is presented.Basic principles of measurements of the tissue optical properties and techniques used for processing of the measured data are outlined. 展开更多
关键词 Absorption coefficient scattering coefficient anisotropy factor reduced scattering coefficient refractive index
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Wave Interaction with Dual Circular Porous Plates 被引量:2
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作者 Arpita Mondal R. Gayen 《Journal of Marine Science and Application》 CSCD 2015年第4期366-375,共10页
In this paper we have investigated the reflection and the transmission of a system of two symmetric circular-arc-shaped thin porous plates submerged in deep water within the context of linear theory. The hypersingular... In this paper we have investigated the reflection and the transmission of a system of two symmetric circular-arc-shaped thin porous plates submerged in deep water within the context of linear theory. The hypersingular integral equation technique has been used to analyze the problem mathematically. The integral equations are formulated by applying Green's integral theorem to the fundamental potential function and the scattered potential function into a suitable fluid region, and then using the boundary condition on the porous plate surface. These are solved approximately using an expansion-cure-collocation method where the behaviour of the potential functions at the tips of the plates have been used. This method ultimately produces a very good numerical approximation for the reflection and the transmission coefficients and hydrodynamic force components. The numerical results are depicted graphically against the wave number for a variety of layouts of the arc. Some results are compared with known results for similar configurations of dual rigid plate systems available in the literature with good agreement. 展开更多
关键词 water wave scattering circular-arc-shaped plates hypersingular integral equation Green's integral theorem reflection coefficient energy identity hydrodynamic force
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FUNDAMENTAL RESEARCH ON RADIOFREQUENCY ABLATION OF RAT BRAIN TISSUE BASED ON NEAR-INFRARED SPECTROSCOPY AND MIE THEORY
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作者 GUANGXIA HU ZHIYU QIAN +2 位作者 TIANMING YANG WEITAO LI JIERU XIE 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2010年第3期213-219,共7页
Near-infrared spectroscopy(NIRS)technology and Mie theory are utilized for fundamental research on radiofrequency ablation of biological tissue.Firstly,NIRS is utilized to monitor rats undergoing radiofrequency ablati... Near-infrared spectroscopy(NIRS)technology and Mie theory are utilized for fundamental research on radiofrequency ablation of biological tissue.Firstly,NIRS is utilized to monitor rats undergoing radiofrequency ablation surgery in real time so as to explore the relationship between reduced scattering coefficient(μ_(s)')and the degree of thermally induced tissue coagulation.Then,Mie theory is utilized to analyze the morphological structure change of biological tissue so as to explore the basic mechanism of the change of optical parameters caused by thermally induced tissue coagulation.Results show that there is a close relationship between μ_(s)' and the degree of thermally induced tissue coagulation;the degree of thermal coagulation can be obtained by the value of μ_(s)';when biological tissue thermally coagulates,the average equivalent scattering particle decreases,the particle density increases,and the anisotropy factor decreases. 展开更多
关键词 Near-infrared spectroscopy(NIRs) Mie theory radiofrequency ablation reducing scattering coefficient(μ_(s)') the average equivalent scattering particle radius
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孔隙率对矩形沟槽上垂直多孔屏障的波浪散射效应影响
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作者 Gour Das Rumpa Chakraborty 《哈尔滨工程大学学报(英文版)》 CSCD 2024年第1期85-100,共16页
The effect of porosity on surface wave scattering by a vertical porous barrier over a rectangular trench is studied here under the assumption of linearized theory of water waves.The fluid region is divided into four s... The effect of porosity on surface wave scattering by a vertical porous barrier over a rectangular trench is studied here under the assumption of linearized theory of water waves.The fluid region is divided into four subregions depending on the position of the barrier and the trench.Using the Havelock’s expansion of water wave potential in different regions along with suitable matching conditions at the interface of different regions,the problem is formulated in terms of three integral equations.Considering the edge conditions at the submerged end of the barrier and at the edges of the trench,these integral equations are solved using multi-term Galerkin approximation technique taking orthogonal Chebyshev’s polynomials and ultra-spherical Gegenbauer polynomial as its basis function and also simple polynomial as basis function.Using the solutions of the integral equations,the reflection coefficient,transmission coefficient,energy dissipation coefficient and horizontal wave force are determined and depicted graphically.It was observed that the rate of convergence of the Galerkin method in computing the reflection coefficient,considering special functions as basis function is more than the simple polynomial as basis function.The change of porous parameter of the barrier and variation of trench width and height significantly contribute to the change in the scattering coefficients and the hydrodynamic force.The present results are likely to play a crucial role in the analysis of surface wave propagation in oceans involving porous barrier over submarine trench. 展开更多
关键词 Water wave scattering Rectangular trench Vertical porous barriers Havelock’s inversion formula Multi-term galerkin approximation Reflection and transmission coefficients Energy dissipation Hydrodynamic force
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北京市区秋季气溶胶粒子浓度与特性参数的观测研究 被引量:11
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作者 许万智 赵凤生 +1 位作者 张寅超 杨燕 《安全与环境学报》 CAS CSCD 北大核心 2014年第1期267-272,共6页
对2010年10月和11月北京市区粒径小于2.5pm(PM2,)和2.5~10μm之间(PM2.5-10)的气溶胶粒子质量浓度进行了观测和分析,同时研究了同期的Angstrom指数和散射系数等气溶胶特性参数的变化。结果表明,不同粒径颗粒物的质量浓度与气... 对2010年10月和11月北京市区粒径小于2.5pm(PM2,)和2.5~10μm之间(PM2.5-10)的气溶胶粒子质量浓度进行了观测和分析,同时研究了同期的Angstrom指数和散射系数等气溶胶特性参数的变化。结果表明,不同粒径颗粒物的质量浓度与气溶胶特性参数的逐时日变化明显。PM:,质量浓度在凌晨5时至6时取得最小值,夜间20时至21时取得最大值;PM2.5-10质量浓度则在9时至10时和20时至21时出现双蜂。气溶胶Angstrom指数在下午明显高于上午,最大值出现在16时左右;散射系数高峰出现在17时至18时。2010年10月7—9日出现了显著的灰霾天气,灰霾天气下PM2.5,和PM2.5-10质量浓度均有明显增加。细粒子增多是导致PM25增加和Angstrom指数增大的主要原因。另外,灰疆天气期间散射系数迅速增大,非灰霾天(10月11日)的散射系数只有灰霾天(10月8日)的1.27%。 展开更多
关键词 环境学 北京 PM2 5 PM2 5-10 Angstrom指数 散射系数
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光在多层匹配生物组织中的时域传输模型 被引量:10
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作者 王喜昌 华臻 孟兆昆 《光子学报》 EI CAS CSCD 北大核心 2006年第7期1061-1065,共5页
建立了匹配介质的n层半无限厚频域方程的解,并对频域进行傅里叶变换,计算出时域方程的时间分辨漫反射(Time-resolvedReflectance)·为检验漫射模型的准确性,将时间分辨漫反射与蒙特卡罗(MonteCarlo)模拟结果进行了比较,结果表明两... 建立了匹配介质的n层半无限厚频域方程的解,并对频域进行傅里叶变换,计算出时域方程的时间分辨漫反射(Time-resolvedReflectance)·为检验漫射模型的准确性,将时间分辨漫反射与蒙特卡罗(MonteCarlo)模拟结果进行了比较,结果表明两者符合得很好·研究表明:该时域漫射模型可以判断生物组织和病变的光学特性· 展开更多
关键词 组织光学 生物组织 吸收系数 约化散射系数 蒙特卡罗模拟
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颅脑创伤近红外实时监测技术研究 被引量:6
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作者 毛雯岚 钱志余 +3 位作者 杨天明 何亮 郭丽娜 吴琦 《光谱学与光谱分析》 SCIE EI CAS CSCD 北大核心 2009年第4期922-925,共4页
采用一套专门设计的由微创光纤探头组成的光纤光谱仪生物组织光学参数测试系统,对颅脑创伤的大鼠创伤侧和对照侧进行近红外光谱检测及脑水含量(brain water content:BWC)测定。通过采用Feeney's自由落体撞击法建立大鼠急性局灶性脑... 采用一套专门设计的由微创光纤探头组成的光纤光谱仪生物组织光学参数测试系统,对颅脑创伤的大鼠创伤侧和对照侧进行近红外光谱检测及脑水含量(brain water content:BWC)测定。通过采用Feeney's自由落体撞击法建立大鼠急性局灶性脑挫裂伤模型,以近红外光谱技术和干湿比重法监测伤后脑水肿的变化。实验发现:伤后1h,伤侧脑组织已发生水肿,伤后24~72h,伤侧脑水肿达高峰,随后逐渐下降;用脱水剂后,脑水肿情况逐渐好转,随着药物失效,水肿又一次发生。生物组织优化散射系数(Reduced Scat-tering Coefficient:μ′s)与BWC的变化规律一致,有很好的线性相关性,能够较好的反映脑组织水肿程度以及药物脱水效果。证实近红外光谱技术用于颅脑创伤实时监测的可行性,为颅脑创伤的研究提出了一种新技术。 展开更多
关键词 近红外光谱 优化散射系数 创伤性脑水肿 脑水含量
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用稳态空间分辨光谱技术检测农产品光学参数的研究及应用 被引量:3
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作者 刘志存 王忠义 +4 位作者 黄岚 徐志龙 侯瑞锋 王成 乔晓军 《农业工程学报》 EI CAS CSCD 北大核心 2008年第9期115-120,共6页
基于光子输运理论,针对农产品强散射介质的特点,采用光子输运方程的漫射近似理论,从其解的形式出发,进行以稳态空间分辨光谱技术为基础的农产品光学参数无损测量方法的研究,设计了农产品光学参数的无损检测装置,用以获得吸收系数和约化... 基于光子输运理论,针对农产品强散射介质的特点,采用光子输运方程的漫射近似理论,从其解的形式出发,进行以稳态空间分辨光谱技术为基础的农产品光学参数无损测量方法的研究,设计了农产品光学参数的无损检测装置,用以获得吸收系数和约化散射系数等光学参数。通过对散射与吸收的标准液体模型(Intralipid-10%溶液与Evan’sblue溶液)在波长750nm处的光学参数的测量,对系统进行了测试校准。测试结果表明,系统稳定、可靠并且检测得到组织的光学参数与文献报道的理论值一致。首次应用基于稳态空间分辨光谱方法测量了富士苹果样品的光学参数,检测结果约化散射系数为(0.97711±0.191858)mm-1,吸收系数为(0.00321±0.00076)mm-1;同时测量了番茄样品,其约化散射与吸收系数分别为(1.1345±0.22749)mm-1,(0.00140±0.00045)mm-1;稳态空间分辨光谱方法较时间分辨光谱TRS方法更适合应用在果蔬生产检测中。 展开更多
关键词 稳态空间分辨光谱 光谱分析 品质检测 约化散射系数 吸收系数 苹果 番茄
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应用近红外光谱技术对胶质瘤大鼠射频热疗的实时在位监测研究 被引量:4
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作者 刘华亭 杨天明 +2 位作者 钱志余 郭凯 张立国 《东南大学学报(医学版)》 CAS 2011年第3期436-440,共5页
目的:观察近红外光谱(near-infrared spectroscopy,NIRS)光学参数在胶质瘤射频热疗术中的变化规律,探讨利用NIRS对胶质瘤射频热疗进行实时监测的可行性。方法:将C6胶质瘤细胞注入大鼠脑右侧尾状核建立胶质瘤大鼠模型;在不同时间、温度... 目的:观察近红外光谱(near-infrared spectroscopy,NIRS)光学参数在胶质瘤射频热疗术中的变化规律,探讨利用NIRS对胶质瘤射频热疗进行实时监测的可行性。方法:将C6胶质瘤细胞注入大鼠脑右侧尾状核建立胶质瘤大鼠模型;在不同时间、温度下对荷瘤大鼠进行靶向毁损,观察并记录肿瘤组织射频加热时靶点的NIRS参数,尤其是优化散射系数(reduced scattering coefficient,μ′s)的变化情况。结果:不同时间、温度下NIRS出现特征性变化曲线;当温度不变时,各时间组间μ′s的变化值差异有统计学意义(P<0.05);当时间不变时,各温度组间μ′s的变化值差异亦有统计学意义(P<0.05)。结论:利用NIRS实时活体在位监测胶质瘤大鼠射频热疗的疗效是科学的、可行的。 展开更多
关键词 近红外光谱 优化散射系数 胶质瘤 射频毁损 大鼠
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利用近红外扩散相关谱同时测量生物样品光学特性和动态特性 被引量:2
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作者 王德田 吕恒星 +5 位作者 高鹏 李生福 朱礼国 彭其先 李泽仁 赵剑衡 《红外与毫米波学报》 SCIE EI CAS CSCD 北大核心 2019年第3期389-394,共6页
由于近红外光对于大多数生物样品具有较高的穿透深度,因此近红外光谱技术广泛用于生物医学、化工、食品安全以及农产品等领域的无损检测,但是多局限于生物样品的光学性质测量,即光吸收测量.利用最新研制的近红外光扩散相关谱系统和采用... 由于近红外光对于大多数生物样品具有较高的穿透深度,因此近红外光谱技术广泛用于生物医学、化工、食品安全以及农产品等领域的无损检测,但是多局限于生物样品的光学性质测量,即光吸收测量.利用最新研制的近红外光扩散相关谱系统和采用脂肪乳作为生物样品的替代物,同时测量了国产30%脂肪乳的光学特性和动态特性,约化散射系数约为303 cm^-1 ,吸收系数约为0. 037 cm^-1 ,30%脂肪乳稀释为0. 85%(体积比)浓度后的布朗扩散系数约为8. 40 × 10^- 9 cm^2 /s,根据Stokes-Einstein 关系可推算出脂肪乳的颗粒半径约为253 nm;研究了脂肪乳随时间演化特性,在七天时间内约化散射系数上升106%,布朗扩散系数下降到63%,研究表明利用近红外扩散相关谱系统的光强衰减可以获得生物样品的光学特性(约化散射系数和吸收系数),利用光强随时间的波动可以获得生物样品的动态特性(布朗扩散系数),因此能够更加准确的测量生物样品的性质变化,为生物样品检测提供一种新的技术手段. 展开更多
关键词 光学 近红外光谱 近红外扩散相关谱 布朗扩散系数 吸收系数 约化散射系数
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基于微创光学参数(优化散射系数)测试的创伤性脑水肿甘露醇疗效评估研究 被引量:3
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作者 谢捷如 钱志余 +1 位作者 何亮 杨天明 《光谱学与光谱分析》 SCIE EI CAS CSCD 北大核心 2009年第12期3254-3258,共5页
通过近红外光谱技术对创伤性脑水肿治疗效果进行了评估。首先采用Feeney's自由落体撞击法建立SD大鼠创伤性脑水肿模型。然后利用两种不同剂量的甘露醇进行脱水治疗,同时应用自制的近红外(near infrared spectroscopy:NIRs)微创探头... 通过近红外光谱技术对创伤性脑水肿治疗效果进行了评估。首先采用Feeney's自由落体撞击法建立SD大鼠创伤性脑水肿模型。然后利用两种不同剂量的甘露醇进行脱水治疗,同时应用自制的近红外(near infrared spectroscopy:NIRs)微创探头对脑组织进行在体实时监测,作为对比同时采用干湿比重法测量各监测时间点的脑水含量。最后根据近红外光谱技术实时监测的数据分析给药前后脑组织皮质优化散射系数(Reduced Scattering Coefficient:μ′s)的变化规律,并结合脑水含量的变化情况,评估了不同剂量的甘露醇治疗创伤性脑水肿的疗效。根据实验结果得到结论:大脑皮层局部优化散射系数可以作为甘露醇疗效的实时评估参考指标参数,并且这种方法可以在体实时监测而不需处死动物,为将来颅脑损伤的实时疗效评估提出了一种方法。 展开更多
关键词 创伤性脑水肿 近红外光谱 优化散射系数 甘露醇
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