Maternal Genistein Intake Can Reduce Body Weight in Male Offspring

The study objectives were to investigate the relationship between early exposure to genistein and obesity in young adulthood and to evaluate changes in reproductive health during puberty and adulthood following in utero exposure to genistein.

Ensemble Nonlinear Support Vector Machine Approach for Predicting Chronic Kidney Diseases

Urban living in large modern cities exerts considerable adverse effectson health and thus increases the risk of contracting several chronic kidney diseases (CKD). The prediction of CKDs has become a major task in urbanizedcountries. The primary objective of this work is to introduce and develop predictive analytics for predicting CKDs. However, prediction of huge samples isbecoming increasingly difficult. Meanwhile, MapReduce provides a feasible framework for programming predictive algorithms with map and reduce functions.The relatively simple programming interface helps solve problems in the scalability and efficiency of predictive learning algorithms. In the proposed work, theiterative weighted map reduce framework is introduced for the effective management of large dataset samples. A binary classification problem is formulated usingensemble nonlinear support vector machines and random forests. Thus, instead ofusing the normal linear combination of kernel activations, the proposed work creates nonlinear combinations of kernel activations in prototype examples. Furthermore, different descriptors are combined in an ensemble of deep support vectormachines, where the product rule is used to combine probability estimates ofdifferent classifiers. Performance is evaluated in terms of the prediction accuracyand interpretability of the model and the results.

Recent Development on Theory and Application of Variable Gauge Rolling, a Review

Variable gauge rolling （VGR） is a new technology for producing the materials which have the advantage of lightweight due to optimized thickness according to load distribution. The new progresses in the theoretical research and application of VGR are reviewed in this paper. Two basic equations, VGR-f and VGR-s, were deduced. The former is a new differential equation of force equilibrium, and the latter is a new form of formula for the law of mass conservation. Both of them provide a new base for the development of VGR analysis. As the examples of VGR＇s application, tailor rolled blank （TRB） and longitudinal profile （LP） plate are introduced. Now TRBs are only produced in Germany and China, and have been used in the automotive manufacturing to play an important role in lightweight design. LP plates have been used in shipbuilding and bridge construction, and promised a bright prospect in reducing construction weight. In addition, new technologies and applications of VGR emerge constantly. Tailor welded strips and tailor rolled strips with variable thickness across the width can be used for progressive die and roll forming. The 3D profiled blank can be obtained by two-step rolling process. Tailor tubes witli the variable wail thickness are an efficient way to reduce the weight. The blank with tailored thickness and mechanical property is also under development. Above products based on the tailored ideas provide a new materials-warehouse for the designers to select so as to meet the needs of weight reducing and material saving.