Evaluation of Clinical Efficacy of Wumen Acupuncture in the Adju-vant Treatment of Non-arteriticAnterior Ischemic Optic Neuropathy

[Objectives]To explore the clinical efficacy of Wumen acupuncture in the adjuvant treatment of non-arteritic anterior ischemic op-tic neuropathy(NAION).[Methods]From June 2023 to April 2024,40 NAION patients were randomly divided into treatment group(Wu-men acupuncture method+methylprednisolone sodium succinate+compound Danshen dripping pills orally)and control group(methylpred-nisolone sodium succinate+compound Danshen dripping pills orally).The clinical symptoms such as fundus condition and visual field were compared between the two groups before treatment,after 2 courses of treatment and 6 months after the first diagnosis.[Results](i)After 2 courses of treatment,the patients with optic disc edema in the treatment group were more than those in the control group,and the difference was significant(P<0.05).The number of patients with retinal hemorrhage in the treatment group was less than that in the control group,and the difference was significant(P<0.05).The color of the optic nerve in the treatment group was less than that in the control group,and the difference was not significant(P>0.05).(ii)Six months after the first diagnosis,the improvement of fundus in the treatment group was bet-ter than that in the control group(P<0.05).After 2 courses of treatment and 6 months after the first diagnosis,the visual evoked potential was significantly improved compared with the control group(P<0.05).After 2 courses of treatment and 6 months from the first diagnosis,the number of lines of visual acuity improvement in the treatment group was greater than that in the controlgroup(P<0.05).After 2 courses of treatment and 6 months from the first diagnosis,the average visual field defect in the treatment group was lower than that in the control group(P<0.05).[Conclusions]Wumen acupuncture method can significantly improve the symptoms of patients with non-arteritic anterior ische-mic optic neuropathy,which is worthy of clinical promotion.

A Meta-analysis of the spirit turtle eight method Acupuncture Therapy for Insomnia

Objective:To systematically evaluate the efficacy and safety of the spirit turtle eight method acupuncture therapy in the treatment of insomnia,to better serve the clinic and provide reference ideas for the treatment of insomnia.Methods:Search CNKI,CBM,Wanfang,Weipu,China Clinical Trial Registry databases on the use of the spirit turtle eight method compared with others interventions to treat insomnia.The search period is from the library until August 1,2021,two researchers will conduct independent quality evaluation and effect size extraction on the literature,and use STATA16.0 and Review5.3 to conduct Meta analysis and quality evaluation on the literature.Through screening,a total of 18 eligible documents participated in the meta-analysis,with a total of 1583 cases.Results:①The effective rate of the spirit turtle eight method in the treatment of insomnia is higher than the control group[RR=1.213,95%CI(1.155,1.274),Z=7.71,P<0.01];②The Pittsburgh Sleep Quality Index(PSQI)score is lower than other acupuncture treatments[WMD=-2.33,95%CI(-2.75,-1.91),Z=10.97,P<0.01];③The one-month follow-up PSQI score after the treatment of insomnia by the spirit turtle eight method is lower than the control group[WMD=-3.263,95%CI(-3.446,-3.080),Z=34.96,P<0.01];④No studies have reported serious adverse reactions in the treatment group and control group.Conclusion:Based on the current research,the spirit turtle eight method are better than the control group in the treatment of insomnia,and are suitable for clinical application.However,more high-quality clinical studies are still needed to prove its efficacy.

"Meridian-sinew Acupuncture Method"Improves Deformity Joint Dysfunction in Rheumatoid Arthritis

Joint deformity and dysfunction are common and serious complications in the late stage of rheumatoid arthritis,which seriously affect the quality of life of patients.Traditional Chinese medicine(TCM)believes that joint deformity and dysfunction in some patients with rheumatoid arthritis are closely related to the apraxia of meridians and tendons due to enduring illness.Based on the theory of meridians and tendons circulation,using the local and nearby therapeutic effect of acupoints as the treatment method in clinical practice,we conducted penetration needling of Houxi,Baxie,Wailaogong as well as Ashi points of interphalangeal joints of both hands through bilateral Sanjian,and used the uniform reinforcing-reducing method to soothe tendons and meridians,thus effectively improving the dysfunction of deformed joints.

Exploring the mechanism of Xingnao Kaiqiao acupuncture method for ischemicstroke based on EEG dynamic changes: a study protocol of an exploratory,prospective,interventional trial

Background: The Xingnao Kaiqiao acupuncture method, founded by Academician ShiXuemin, has outstanding efficacy in the treatment of ischemic stroke and has been widelyused at home and abroad. However, after half a century of animal experiments and clinicalstudies, clearly and intuitively revealing its therapeutic mechanism is still a great challengefor researchers. Therefore, this experiment is based on the combination of medicine andengineering to study the immediate effects of the acupuncture method in treating patientsby recording the electroencephalography (EEG) activities of subjects during the acupunctureprocess and to further reveal the therapeutic mechanism at the brain level. Methods: Thistrial is an exploratory, prospective, single-arm interventional study involving a total ofpatients with ischemic stroke. Physicians will record EEG data from patients duringacupuncture as the primary outcome indicator. After pre-processing the EEG data,researchers will use various methods to analyze the immediate effects of acupuncture toobtain brain effectiveness. Deep learning will then be used to identify acupoint stimuli andreceive correspondence between the acupuncture effect and the brain’s internal state.National Institutes of Health Stroke Scale score before and after the acupuncture process willbe used as the secondary outcome indicator. Conclusion: This is the first study protocol toapply dynamic changes in EEG to explore a range of mechanisms of action of acupuncture inthe treatment of ischemic stroke. We propose a method to analyze EEG signals ofacupuncture patients. The deep learning model will be applied for supervised training toobtain the compelling relationship between the acupuncture method and internal brainstates, providing a new prospect for the digitization of traditional Chinese medicine.

TWO-STEP REGULATION METHOD OF ACUPUNCTURE IN THE TREATMENT OF INTRACTABLE FACIAL PARALYSIS OBSERVATION ON 96 CASES

Two step regulating acupuncture therapy was employed in the treatment of 96patients with intractable facial paralysis and the therapeutic effects of the method is compared withthat in 40 patients in control.In the first step,strong regulating acupuncture was applied at Meixin(EXtra),upper Taiyang (EX-HN 5) and Xiaguan (ST 7) points in the affected face.In the secondstep,weak regulating acupuncture was used at Dicang (ST 4) and Sibai (ST 2) points in the healthface.It was revealed that among the 96 patients,37 cases (38. 5%) were cured,57 cases (59. 4%)markedly improved,2 cases (2.1%) improved with a total effective rate of 100%.The effective ratewas statistically different (P【0. 005) from that in the control.The results indicate that the method issuperior to the ordinary manipulation in treating intractable facial paralysis.

Acupuncture Combined with Plucking Muscle Method for Treatment of 48 Cases of Acute Lumbar Sprain

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CLINICAL AND EXPERIMENTAL RESEARCH ON APOPLECTIC SEQUELAE TREATED WITH “XINGNAO KAIQIAO”(XNKQ) ACUPUNCTURE METHOD

The research sumed up the main acupoints of prescription and clinical therapeutic effects of apoplectic sequelae.In the series, 60 in-patients were observed, they were divided into two groups at random, 30 cas es in the Xing Nao Kai Qiao group, 30 cases in the traditional group. There are compara bility on different diseases, courses of the disease, ages and so on between the two groups. On the treatment method, Xing Nao Kai Qiao acupuncture manipulation and acupoints prescription were adopted in the Xing Nao group, and the method descriped in the fifth edition textbook was applied in the traditional group. Acupuncture treatment was given two times a day. After 60 days, evaluation of clinital therapeutic effects were made and the changes of blood rheology, blood liPOids microcirculation and electromyogram in the two groups were observed before and after acupuncture treatment. The re sults of therapeutic effects suggested that the cure rates were 26. 67% in the 6. 67 % in the Xng Nao group and traditional group respectively, obvious improvement rates were 46. 69 % and 20.00% re spectively in the two groups. There was an obvious difference between the two groups according to sta tistical analysis (P<0.05, P <0.01 ). It showed that Xing Nao Kai Qiao acupuncture method could obviously improve blood rheology and blood-lipoids (P <0.05 ), and played an active regulation role in the nail fold microcirculation. After treatment, electromyogram showed that electric potential of motor unit was markedly incrcased, myodynamia became stronger. It indicated that the Xing Nao Kai Qiao acupuncture method was better than the traditional acupuncture method on the treatment of apoplectic sequelae. It is worth popularizing.

Observation on the Treatment of Belt Vessel Lumbago by Daoyin method with Acupuncture

Objective:To observe the clinical efficacy of Daoyin method with acupuncture on belt vessel type lumbago,and to evaluate the effectiveness of the method.Methods:A total of 54 patients with belt vessel type lumbago who met the inclusion criteria were randomly divided into two groups,with 27 patients in both groups.Patients in the treatment group were treated by Daoyin with acupuncture on the belt vessel,patients in the control group only received acupuncture on the belt vessel.The visual analogue scale,JOA score,ODI score,and SBI score before and after treatment were observed.Results:There were significant differences in the score changes in both groups before and after treatment,and the difference between the treatment group and the control group was significant.The therapeutic effect in the treatment group is better than the control group.Daoyin with acupuncture has a better effect on belt vessel type lumbago.

Orthogonal design to sift the optimal parameter of Neiguan acupuncture for cerebral infarction

The individual difference and non-repeatability in acupuncture have not only restricted the devel- opment of acupuncture, but have also affected the specificity of acupoints. The present study used instruments to control needle depth, lifting and thrusting frequency, and the duration of acupuncture. Effects of the quantified acupuncture were observed at Neiguan （PC6） with different stimulation parameters. A frequency of 1, 2, or 3 Hz and duration of 5, 60, or 180 seconds were used to observe cerebral blood flow and ratio of infarct volume recovery. Results showed that stimulation at Neiguan with a frequency of 1 Hz and long duration of 180 seconds or 2/3 Hz and long duration of 5/60 seconds significantly increased cerebral blood flow and decreased the ratio of infarct volume. In- teractions between frequency and duration play a critical role in quantified acupuncture therapy.

PRACTICE AND DEVELOPMENT ON ZHU'S AND CHAU'S SCALP ACUPUNCTURE

Zhu’s and Chau’s Scalp Acupuncture is one of the newly developed needling meth-ods which follows the "penetrating head acu-point needling" method. Through many years ofclinical experience, exploration and research in conjunction with the various advantages of differ-ent styles and sects of scalp acupuncture needling methods, a unique method of scalp acupuncturehas been developed. This method combines the modern medical theory and the traditional Chinesemedical theory. The region of head is divided into seven treatment areas: Shenting region (GV24), Touwei region (ST 8), Shuaigu region (GB 8), Baihui region (GV 2O), Qiangjian region(GV 18), Xinhui region (GV 22), Wangu region (GB 12). The manipulation is developed andcreated according to the Collection of Acupuncture and Moxibustion, Chouqi and Jinqi methods.In the process of the insertion of the needles, this method requires the cooperation of rapid andslow breathing by lifting, following and opposing the meridian course, including active and pas-sive

Modulation of electroencephalograph activity by manual acupuncture stimulation in healthy subjects:An autoregressive spectral analysis

To investigate whether and how manual acupuncture（MA） modulates brain activities,we design an experiment where acupuncture at acupoint ST36 of the right leg is used to obtain electroencephalograph（EEG） signals in healthy subjects.We adopt the autoregressive（AR） Burg method to estimate the power spectrum of EEG signals and analyze the relative powers in delta（0 Hz-4 Hz）,theta（4 Hz-8 Hz）,alpha（8 Hz-13 Hz）,and beta（13 Hz-30 Hz） bands.Our results show that MA at ST36 can significantly increase the EEG slow wave relative power（delta band） and reduce the fast wave relative powers（alpha and beta bands）,while there are no statistical differences in theta band relative power between different acupuncture states.In order to quantify the ratio of slow to fast wave EEG activity,we compute the power ratio index.It is found that the MA can significantly increase the power ratio index,especially in frontal and central lobes.All the results highlight the modulation of brain activities with MA and may provide potential help for the clinical use of acupuncture.The proposed quantitative method of acupuncture signals may be further used to make MA more standardized.

Mechanism of"Five Meridians Acupuncture"in Treating Postoperative Urinary Retention after Anorectal Diseases

In recent years,with the change of rhythm and eating habits of the public,the number of patients with anorectal diseases has gradually increased,and postoperative urinary retention has also become more common.Urinary retention refers to the symptoms of anorectal diseases and is caused by improper urination and incompletion of urination due to surgical and pain causes that result in bladder and urine filling and are accompanied by lower abdominal distention and pain.In traditional Chinese medicine,acupuncture is simple and effective as a treatment.In this article,we focus on five meridians that pass through the lower abdomen Ren meridian,kidney meridian,spleen meridian,stomach meridian,and liver meridian,namely the"five meridians,"and study the mechanism of action so as to provide new therapeutic ideas for clinical acupuncture treatment of postoperative urinary retention of anorectal diseases.

OBSERVATION ON THERAPEUTIC EFFECT OF ELECTROACUPUNCTURE HEAD PONINT-THROUGH-POINT BY PENETRATING TWO POINT ON ISCHEIC STROKE

Objective To probe methods and therapeutic effects of Head Acupuncture on ischemic stroke. Methods One hundred and twelve cases were randomly divided into observation group (head acupuncture group) and control group (body acupuncture group). After treatment of 28 days, changes of linguistic function and paralysis level of limbs before and after treatment were investigated. Results The total effective rate was 96.6% in the observation group and 90.7%, in the control group, with a significant difference between the two groups (P<0.05). Conclusion The electroacupuncture head point-through-point by penetrating two point therapy is one of effective methods for ischemic stroke.

REVIEW AND PROSPECT OF THE TREATMENT OF APOPLEXY BY ACUPUNCTURE

By review of clinical reports on the treatment of apoplexy in the recent ten years, the authors analyse the main factors influencing the effect of treatment, and point out that for further improvement of the treatment effect of this disease, a strict design of the subject is needed, and it is necessary for the causes and pathogenesis of apoplexy to be analysed, so as to get a clear understanding of the relations among various factors affecting the effect of the treatment and the principal and subordinate position, then the best plan for treatment can only be selected.

THE EFFECT OF WARM ACUPUNCTURE ON RHEUMATOID ARTHRITIS OF 434 CASES

Clinical observation on 434 cases of rheumatoid arthritis shows that the warmingneedle method is markedly effective for rheumatoid arthritis (RA). It also helps to reveal the mecha-nism and function of acupuncture and moxibustion (AM) in curing diseases. Laboratory observationconfirms that the warming needle method can modulate the body’s immunity function significantly. Inthe future, more attention should be paid to point selection and manipulation method so that the bestresult can be obtained.

Acupuncture and Moxibustion Theories of Zhang Ji

This paper introduces the clinical experiences on acupuncture and moxibustion of Zhang Zhongjing, who was regarded as “medical Saint” of Traditional Chinese Medicine. He gave indications for acupuncture and moxibustion, developed robbing fire or inversing fire acupuncture principles to treat febrile diseases. His theories on acupuncture and moxibustion are precious and could be reference in clinical practice.

Effects of cluster needling of scalp acupuncture on neurofilament protein 200 and signal transducer and activator of transcription 3 in rats with acute cerebral ischemia

Objective:Cluster needling at scalp acupoints has showed satisfying effects with acute cerebral ischemia in clinic whereas the mechanisms are not yet clear completely.This study investigated the influence of cluster needling at scalp acupoints on neurological function,as well as on neurofilament protein 200(NF200)and signal transducer and activator of transcription 3(STAT3)expression,in rats with acute cerebral ischemia.Methods:Fifty-four Sprague-Dawley rats were randomly assigned in equal numbers to the false operation(group F),model(group M),or cluster needling scalp acupuncture(group C)groups.Each group was divided into three subgroups,of six rats each,by acupuncture treatment time(24 h,7 days,and 14 days).The rat local cerebral ischemia model was prepared using a modified suture occlusion method.Group C rats were treated by cluster needling scalp acupuncture,while groups F and M did not receive acupuncture treatment.Neurological effects were evaluated using the Longa score.NF200 and STAT3 expression were measured by western blotting.Results:At 24 h,there were no statistical difference between group C and group M in nerve function(P>.05).On days 7 and 14,nerve function scores in group C were significantly lower than that in group M(respectively were P<.05 and P<.01).In addition,on days 14,expression of NF200 was significantly higher in group C compared with group M(P<.05).Compared with group M,STAT3 expression was also higher in group C on days 7 and 14,although these differences were not statistically significant(both P>.05).Conclusion:Cluster needling scalp acupuncture were efficient in improving nerve function scores in rats with cerebral ischemia,and promoting the recovery of motor function.These improvements were associated with increases in NF200 and STAT3 expression.

CLINICAL STUDY ON LASER NEEDLE-KNIFE AND ACUPUNCTURE FOR VERTEBRAL-ARTERY-TYPE CERVICAL SPONDYLOSIS

Objective To compare the effect of laser needle-knife and acupuncture with medication for vertebral-artery-type cervical spondylosis （CSA）. Methods The 88 outpatients of CSA were divided with single-blind method into Treatment Group （treated by laser needle-knife and acupuncture） with 48 patients in it and Control Group （treated by Intravenous drip of Compound Salvia Miltiorrhiza Injection and oral taking of Flunarizine （Sibelium） with 40 patients in it. Before the treatment, the two groups were without difference statistically. Results In the treatment group, the curative rate was 60.42% and the total effective rate 97.92%. In the control group, the curative rate was 30% and the total effective rate 87.5%. In statistics, P〈0.05, a significant difference existed between the two groups. Conclusion The effect of laser needleknife and acupuncture for CSA is obviously better than that of medication, worth spreading.

针刺对肩周炎患者生存质量改善及临床效果研究

目的研究针刺治疗后肩周炎患者的临床疗效和生存质量改善情况。方法严格按照纳入排除标准选择2022年3月—2023年3月收治的80例肩周炎患者进行研究,按照等比例随机数字表法分为两组,对照组40例采用口服药物+功能锻炼治疗,研究组40例采用经络别通法针刺治疗,治疗1个疗程后观察比较两组临床疗效、肩关节功能、日常生活能力、炎症因子水平以及疼痛恢复情况。结果研究组治疗总有效率(97.50%,39/40)显著高于对照组(77.50%,31/40),差异有统计学意义(P<0.05);均未发生严重安全事件,仅少数患者发生不良反应,差异无统计学意义(P>0.05)。治疗前,两组肩关节评分量表(CMS)分值、疼痛程度、简化生活质量量表(ADL)评分和炎症因子水平比较差异均无统计学意义(P>0.05);治疗后,研究组CMS分值、ADL评分高于对照组,疼痛状况(PPI)分值、视觉模拟疼痛(VAS)分值、疼痛分级指数(PRI)分值、C反应蛋白(CRP)、白介素-1β(IL-1β)、肿瘤坏死因子-α(TNF-α)水平低于对照组,差异有统计学意义(P<0.05)。结论经络别通法针刺治疗肩周炎疗效显著,可显著改善疼痛,从而改善患者生存质量,相关作用机制可能与降低炎症因子水平,恢复肩关节功能相关。

经筋透刺法联合穴位注射治疗顽固性面瘫60例临床观察

目的探讨经筋透刺法联合穴位注射治疗顽固性面瘫的临床疗效。方法选取2020年5月至2021年10月在遂宁市中医院接受治疗的120例顽固性面瘫病人,采用随机数字表法随机分为单一组(60例)和联合组(60例),两组病人均给予常规西药治疗,单一组在此基础上给予穴位注射,联合组在此基础上给予经筋透刺法联合穴位注射,比较两组病人治疗前后面神经功能、神经生长因子(NGF)和胶质细胞源性神经营养因子(GDNF)水平、神经功能分级(H-B)评分、面瘫Portmann评分、Sunnybrook量表、复发率及临床疗效。结果单一组和联合组治疗后面神经功能明显改善,且联合组面神经功能改善情况明显优于单一组(P<0.05);单一组H-B评分治疗后较治疗前降低(2.63±0.54)分比(4.01±0.73)分,联合组(1.67±0.49)分比(4.03±0.71)分(P<0.05),且联合组H-B评分低于单一组(P<0.05),单一组和联合组GDNF(12.16±3.33)mg/L比(8.92±1.35)mg/L、(15.54±3.42)mg/L比(8.89±1.37)mg/L、NGF水平(12.16±3.33)mg/L比(8.92±1.35)mg/L、(15.54±3.42)mg/L比(8.89±1.37)mg/L、面瘫Portmann评分(15.31±1.03)分比(6.69±0.68)分、(17.24±1.16)分比(6.72±0.71)分、Sunnybrook量表评分(69.16±10.67)分比(36.42±10.17)分、(78.64±11.56)分比(36.17±10.13)分治疗后较治疗前升高,且联合组GDNF、NGF水平、面瘫Portmann评分、Sunnybrook量表评分高于单一组(P<0.05);联合组总复发率(3.33%)低于单一组(13.33%)(P<0.05);联合组总有效率(90.00%)明显高于单一组(75.00%)(P<0.05)。结论经筋透刺法联合穴位注射可改善顽固性面瘫病人临床症状及面神经功能,疗效较好且复发率较低。