Background: Lack of available reference values in a research setting under local conditions can be a drawback for beginners, as the accuracy of data from control samples cannot be checked at the beginning of a researc...Background: Lack of available reference values in a research setting under local conditions can be a drawback for beginners, as the accuracy of data from control samples cannot be checked at the beginning of a research project. This affects comparisons with data from test samples. To avoid these complications in their research projects,beginners tend to have a greater number of animals in the control group compared to test groups in order to have control group measurements within 2 SDs of the mean.Methods: As non-availability of reference values was a long-felt need, the described project was conducted in order to establish a reference database for selected haematological, biochemical and physiological parameters using apparently healthy Sprague-Dawley rats bred in the Animal House of Faculty of Medicine, University of Colombo(UCFM).Results: Differences in mean values of packed cell volume(PCV), mean corpuscular volume(MCV) and mean corpuscular hemoglobin concentration(MCHC), serum creatinine and blood glucose levels between the two genders were statistically significant. Lipid profile measurements did not differ significantly between genders, but mean and median values of triglycerides(TG) between male and female rats showed a difference of more than 10 mg/dL. The liver enzymes alkaline phosphatase(AP)and aspartate aminotransferase(AST) were also statistically significantly different between sexes. Despite wide variation in mean alanine aminotransferase(ALT)between sexes, the difference was not statistically significant.Conclusion: The findings of this project should support to a certain extent the"Reduction" aspect of the 3 Rs concept of Russell and Burch by reducing the number of Sprague-Dawley rats used in future research projects at UCFM.展开更多
由于可见光通信中可能会受到很多噪声干扰,信道编码受到了广泛的重视,它是重要的通信纠错方法,为改善可见光通信的信道译码性能,提高信息传输效率,降低译码复杂度,采用一种将RS码与LDPC码级联的方案。RS码具有很强的处理突发错误的能力,...由于可见光通信中可能会受到很多噪声干扰,信道编码受到了广泛的重视,它是重要的通信纠错方法,为改善可见光通信的信道译码性能,提高信息传输效率,降低译码复杂度,采用一种将RS码与LDPC码级联的方案。RS码具有很强的处理突发错误的能力,LDPC码具有接近香浓极限的良好性能。该方案实现简单,复杂度低。经仿真结果表明,该方法与未编码时相比,误码率低,纠错能力有明显提升,而且比较级联码中LDPC码不同码长的性能,误码率为10-3时,编码增益提高2 d B左右,适合可见光通信的实际应用的要求。展开更多
文摘Background: Lack of available reference values in a research setting under local conditions can be a drawback for beginners, as the accuracy of data from control samples cannot be checked at the beginning of a research project. This affects comparisons with data from test samples. To avoid these complications in their research projects,beginners tend to have a greater number of animals in the control group compared to test groups in order to have control group measurements within 2 SDs of the mean.Methods: As non-availability of reference values was a long-felt need, the described project was conducted in order to establish a reference database for selected haematological, biochemical and physiological parameters using apparently healthy Sprague-Dawley rats bred in the Animal House of Faculty of Medicine, University of Colombo(UCFM).Results: Differences in mean values of packed cell volume(PCV), mean corpuscular volume(MCV) and mean corpuscular hemoglobin concentration(MCHC), serum creatinine and blood glucose levels between the two genders were statistically significant. Lipid profile measurements did not differ significantly between genders, but mean and median values of triglycerides(TG) between male and female rats showed a difference of more than 10 mg/dL. The liver enzymes alkaline phosphatase(AP)and aspartate aminotransferase(AST) were also statistically significantly different between sexes. Despite wide variation in mean alanine aminotransferase(ALT)between sexes, the difference was not statistically significant.Conclusion: The findings of this project should support to a certain extent the"Reduction" aspect of the 3 Rs concept of Russell and Burch by reducing the number of Sprague-Dawley rats used in future research projects at UCFM.
文摘由于可见光通信中可能会受到很多噪声干扰,信道编码受到了广泛的重视,它是重要的通信纠错方法,为改善可见光通信的信道译码性能,提高信息传输效率,降低译码复杂度,采用一种将RS码与LDPC码级联的方案。RS码具有很强的处理突发错误的能力,LDPC码具有接近香浓极限的良好性能。该方案实现简单,复杂度低。经仿真结果表明,该方法与未编码时相比,误码率低,纠错能力有明显提升,而且比较级联码中LDPC码不同码长的性能,误码率为10-3时,编码增益提高2 d B左右,适合可见光通信的实际应用的要求。
