Spatial Distribution of Meteorological Factors During the Key Growth Periods of Apple Cultivation in Longdong Region of Gansu Province

With the ongoing development of the apple industry in the Longdong region of Gansu,this sector has emerged as a key driver for the government s initiatives aimed at increasing stable income for local residents and promoting rural revitalization.The Longdong region boasts a favorable geographical location and a suitable climatic environment,making it an ideal area for apple cultivation.This paper analyzes meteorological data from the national meteorological observatory in Longdong over the past forty years,focusing on average temperature,precipitation,sunshine duration,and relative humidity during three critical growth periods of apples.The research reveals significant differences in the distribution of meteorological conditions across these key growth stages.Notably,the average temperature is higher in the central and northern parts of the region,while lower temperatures are observed in the southwestern areas.The average daily maximum temperature tends to be higher in the northwest and lower in the central and southwestern regions.Conversely,the average daily minimum temperature demonstrates a distinct pattern,being higher in the south and lower in the north.Additionally,precipitation is more abundant in the southeast and less so in the northwest.Sunshine hours are greater in the northern and central regions,while the southwestern and northeastern areas receive fewer hours of sunlight.Finally,relative humidity is higher in the south and lower in the north.

Normothermic regional perfusion mobile teams in controlled donation after circulatory death pathway: Evidence and peculiarities

To facilitate the implementation of controlled donation after circulatory death(cDCD)programs even in hospitals not equipped with a local Extracorporeal Membrane Oxygenation(ECMO)team(Spokes),some countries and Italian Regions have launched a local cDCD network with a ECMO mobile team who move from Hub hospitals to Spokes for normothermic regional perfusion(NRP)implantation in the setting of a cDCD pathway.While ECMO teams have been clearly defined by the Extracorporeal Life Support Organization,regarding composition,responsibilities and training programs,no clear,widely accepted indications are to date available for NRP teams.Although existing NRP mobile networks were developed due to the urgent need to increase the number of cDCDs,there is now the necessity for transplantation medicine to identify the peculiarities and responsibility of a NRP team for all those centers launching a cDCD pathway.Thus,in the present manuscript we summarized the character-istics of an ECMO mobile team,highlighting similarities and differences with the NRP mobile team.We also assessed existing evidence on NRP teams with the goal of identifying the characteristic and essential features of an NRP mobile team for a cDCD program,especially for those centers who are starting the program.Differences were identified between the mobile ECMO team and NRP mobile team.The common essential feature for both mobile teams is high skills and experience to reduce complications and,in the case of cDCD,to reduce the total warm ischemic time.Dedicated training programs should be developed for the launch of de novo NRP teams.

Path Analysis of High-Quality Development of Regional Economy The Role and Impact of Industrial Policies

With China’s economic development entering a new normal,high-quality regional economic development has become an important goal of current economic development.As one of the important means to promote high-quality development of the regional economy,industrial policies are increasingly receiving attention in terms of their role and impact.This article mainly conducts an in-depth analysis of the mechanism and impact path of industrial policies,exploring the role and impact of industrial policies in promoting high-quality regional economic development.Firstly,industrial policies play an important role in promoting high-quality regional economic development.Secondly,the impact path of industrial policies on the high-quality development of the regional economy mainly includes promoting industrial structure upgrading,promoting technological innovation,guiding resource allocation,and enhancing enterprise competitiveness.Therefore,it is necessary to increase research and practice on industrial policies,continuously optimize policy measures,and promote high-quality development of the regional economy.

Sequence Difference of Mitochondrial DNA Control Region and Genetic Differentiation of Cervinae in China

[Objective] The study aimed at analyzing Genetic Differentiation of Cervinae. [Method] The complete mitochondrial DNA control region of five species of Cervinae was determined by direct DNA sequencing. Homologous sequences of others Cervinae were gained from GenBank, and then analyzed through biology software. [Result] The lengths of their control region were 921-1 072 bp, the nucleotide content of T, A, C, and G was 32.1%, 30.2%, 22.7% and 15.0% separately. Genetic distance of each species ranged from 0.062-0.106, which belonged to level of inter-genus. The molecular phylogenetic tree indicated that red deer, skia deer and White-lipped Deer had close relationship, and they constituted one branch with sambar deer. Eld＇s deer and elk deer constituted the second branch, and hog deer constituted the third branch alone. [Conclusion] Hog deer and fallow deer should be incorporated in Cervus, divergence time is about 1.55-2.60 million years among Cervinae in China.

A Molecular Phylogeny of Macaca Based on Mitochondrial Control Region Sequences

Nucleotide sequences of segments of the mitochondrial control regions were analyzed to infer the phylogenetic relationships among 7 macaques.High nucleotide diversity in Macaca assamensis and relatively low diversity in M.thibetana were found.Based on the ML tree from control regions,species in our study can roughly be sorted into three species groups except for the phylogenetic position of M.fascicularis,i.e.,silenus group,including M.leonina;sinica group,including M.arctoides,M.assamensis,and M.thibetana;and fascicularis group,including M.mulatta and M.cyclopis.A discrepancy between earlier studies (Fooden & Lanyon,1989;Tosi et al,2003a;Deinard & Smith,2001;Evans et al,1999;Hayasaka et al,1996;Morales & Melnick,1998),our result supported the hypothesis that M.fascicularis diverged earlier than M.leonina.Mitochondrial paraphyly in eastern M.mulatta (with respect to M.cyclopis) and eastern M.assamensis (with respect to M.thibetana) were clearly observed in our study.In accordance with the results of Y chromosome,allozyme,nuclear genes and some morphological data (Delson,1980;Fooden & Lanyon,1989;Fooden,1990;Tosi et al,2000,2003a,b;Deinard & Smith,2001),our study on control region sequences supported M.arctoides to be classified into the sinica group.However,this result disagreed with the previous mtDNA studies (Hayasaka et al,1996;Morales & Melnick,1998;Tosi et al,2003a).

Identifying Regional Prolonged Low Temperature Events in China

This study examined regional prolonged low temperature （PLT） events in China from the observational station data for the period 1960–2008 using the new criteria. The new definition of a site PLT event is that the daily minimum temperature does not exceed the 10th percentile threshold of the local daily minimum temperature climatology for at least 5 days at a station. The regional PLT event is defined as at least five adjacent stations exhibiting site PLT simultaneously for 5 d. Under the new definition, 552 regional PLT events were identified, and three indices： duration, extent, and intensity, as well as a comprehensive index （CI） were used to quantify the event severity. In addition, geographical patterns and temporal variations of regional PLT events were investigated using three event categories： strong, moderate, and weak. Spatially, strong events were mainly located in the north of Xinjiang and along the Yangtze River to the south of the Yangtze River; moderate events occurred in Xinjiang and south of the Yangtze River; and weak events occurred south of the Yellow River. The variation for the annual frequency of regional PLT events in China in the last 49 years showed a significant decreasing trend with a rate of-1.99 times per decade, and the significant transition decade was the 1980s.

Nonbismuth concomitant quadruple therapy for Helicobacter pylori eradication in Chinese regions: A meta-analysis of randomized controlled trials

AIM: To evaluate the applicability of nonbismuth concomitant quadruple therapy for Helicobacter pylori(H. pylori) eradication in Chinese regions.METHODS: A systematic review and meta-analysis of randomized controlled trials was performed to evaluate the efficacy of nonbismuth concomitant quadruple therapy between sequential therapy or triple therapy for H. pylori eradication in Chinese regions. The defined Chinese regions include China, Hong Kong, Taiwan, and Singapore. The primary outcome was the H. pylori eradication rate; the secondary outcome was the compliance with therapy. The Pub Med, Embase, Scopus, and Cochrane databases were searched for studies published in the period up to March 2016 with no language restriction.RESULTS: We reviewed six randomized controlled trials and 1616 patients. In 3 trials comparing concomitant quadruple therapy with triple therapy, the H. pylori eradication rate was significantly higher for 7-d nonbismuth concomitant quadruple therapy than for 7-d triple therapy(91.2% vs 77.9%, risk ratio = 1.17, 95%CI: 1.09-1.25). In 3 trials comparing quadruple therapy with sequential therapy, the eradication rate was not significant between groups(86.9% vs 86.0%). However, higher compliance was achieved with concomitant therapy than with sequential therapy.CONCLUSION: The H. pylori eradication rate was higher for nonbismuth concomitant quadruple therapy than for triple therapy. Moreover, higher compliance was achieved with nonbismuth concomitant quadruple therapy than with sequential therapy. Thus, nonbismuth concomitant quadruple therapy should be the first-line treatment in Chinese regions.

Simulations of a Hydrological Model as Coupled to a Regional Climate Model

Considering a detailed hydrologic model in the land surface scheme helps to improve the simulation of regional hydro-climatology. A hydrologic model, which includes spatial heterogeneities in precipitation and infiltration, is constructed and incorporated into the land surface scheme BATS. Via the coupled-model (i.e., a regional climate model) simulations, the following major conclusions are obtained: the simulation of surface hydrology is sensitive to the inclusion of heterogeneities in precipitation and infiltration; the runoff ratio is increased after considering the infiltration heterogeneity, a result which is more consistent with the observations of surface moisture balance over humid areas; the introduction of the parameterization of infiltration heterogeneity can have a greater influence on the regional hydro-climatology than the precipitation heterogeneity; and the consideration of the impermeable fraction for the region reveals some features that are closer to the trend of aridification over northern China.

Impacts of Global Warming on Hydrological Cycles in the Asian Monsoon Region

The hydrologic changes and the impact of these changes constitute a fundamental global-warmingrelated concern. Faced with threats to human life and natural ecosystems, such as droughts, floods, and soil erosion, water resource planners must increasingly make future risk assessments. Though hydrological predictions associated with the global climate change are already being performed, mainly through the use of GCMs, coarse spatial resolutions and uncertain physical processes limit the representation of terrestrial water/energy interactions and the variability in such systems as the Asian monsoon. Despite numerous studies, the regional responses of hydrologic changes resulting from climate change remains inconclusive. In this paper, an attempt at dynamical downsealing of future hydrologic projection under global climate change in Asia is addressed. The authors conducted present and future Asian regional climate simulations which were nested in the results of Atmospheric General Circulation Model （AGCM） experiments. The regional climate model could capture the general simulated features of the AGCM. Also, some regional phenomena such as orographic precipitation, which did not appear in the outcome of the AGCM simulation, were successfully produced. Under global warming, the increase of water vapor associated with the warmed air temperature was projected. It was projected to bring more abundant water vapor to the southern portions of India and the Bay of Bengal, and to enhance precipitation especially over the mountainous regions, the western part of India and the southern edge of the Tibetan Plateau. As a result of the changes in the synoptic flow patterns and precipitation under global warming, the increases of annual mean precipitation and surface runoff were projected in many regions of Asia. However, both the positive and negative changes of seasonal surface runoff were projected in some regions which will increase the flood risk and cause a mismatch between water demand and water availability in the agricultural season.

Pinning-controlled synchronization of complex networks with bounded or unbounded synchronized regions

This paper studies pinning-controlled synchronization of complex networks with bounded or unbounded synchronized regions. To study a state-feedback pinning-controlled network with N nodes, it first converts the controlled network to an extended network of N＋1 nodes without controls. It is shown that the controlled synchronizability of the given network is determined by the real part of the smallest nonzero eigenvalue of the coupling matrix of its extended network when the synchronized region is unbounded; but it is determined by the ratio of the real parts of the largest and the smallest nonzero eigenvalues of the coupling matrix when the synchronized region is bounded. Both theoretical analysis and numerical simulation show that the portion of controlled nodes has no critical values when the synchronized region is unbounded, but it has a critical value when the synchronized region is bounded. In the former case, therefore, it is possible to control the network to achieve synchronization by pinning only one node. In the latter case, the network can achieve controlled synchronization only when the portion of controlled nodes is larger than the critical value.

Model Predictive Control of Nonlinear Systems: Stability Region and Feasible Initial Control

This paper proposes a new method for model predictive control （MPC） of nonlinear systems to calculate stability region and feasible initial control profile/sequence, which are important to the implementations of MPC. Different from many existing methods, this paper distinguishes stability region from conservative terminal region. With global linearization, linear differential inclusion （LDI） and linear matrix inequality （LMI） techniques, a nonlinear system is transformed into a convex set of linear systems, and then the vertices of the set are used off-line to design the controller, to estimate stability region, and also to determine a feasible initial control profile/sequence. The advantages of the proposed method are demonstrated by simulation study.

Hydrological and water cycle processes of inland river basins in the arid region of Northwest China

The increasing shortage in water resources is a key factor affecting sustainable socio-economic development in the arid region of Northwest China(ARNC). Water shortages also affect the stability of the region's oasis ecosystem. This paper summarizes the hydrological processes and water cycle of inland river basins in the ARNC, focusing on the following aspects: the spatial-temporal features of water resources(including air water vapor resources, runoff, and glacial meltwater) and their driving forces; the characteristics of streamflow composition in the inland river basins; the characteristics and main controlling factors of baseflow in the inland rivers; and anticipated future changes in hydrological processes and water resources. The results indicate that:(1) although the runoff in most inland rivers in the ARNC showed a significant increasing trend, both the glaciated area and glacial ice reserves have been reduced in the mountains;(2) snow melt and glacier melt are extremely important hydrological processes in the ARNC, especially in the Kunlun and Tianshan mountains;(3) baseflow in the inland rivers of the ARNC is the result of climate change and human activities, with the main driving factors being the reduction in forest area and the over-exploitation and utilization of groundwater in the river basins; and(4) the contradictions among water resources, ecology and economy will further increase in the future. The findings of this study might also help strengthen the ecological, economic and social sustainable development in the study region.

ON REGIONAL DIFFERENTIATION OF RIVER WATER ENVIRONMENT CAPACITY AND STRATEGIES TO CONTROL WATER ENVIRONMENT POLLUTION IN CHINA

China has large population and wide territory, the natural conditions of different regions are complicated. water resources are distributed unbalanced.economic developing states are unequal. For these reasons the variation of concerned water environment capacity has obvious character of regional differentiation. In this paper, from the economic development point of view, the regular pattern of regional differentiation of China's water environment capacity resources is analyzed. the concept of contradictory degree between water environment capacity and economic development is introduced, based on them, rivers in China are divided into three regions, and corresponding strategies to control water pollution are advanced. The aims are to use river water environment capacity resources effectively. to control pollution and to improve environmental quality.

Frost heave control of fine round gravel fillings in deep seasonal frozen regions

Fine round gravel soil is widely employed in the subgrade of high and thawing. The lower the fines content in fine round gravel soil, but compaction difficulty increases. This study is to obtain the speed railways in cold regions to prevent frost heaving the smaller the quantities of frost heaving and thawing, optimum fines content and limited frost heaving and thawing. The fine round gravel soil filling （FRGSF） used in the Harbin-Qiqihaer Passenger Dedicated Line is taken as the study object. Influence of fines content on optimum water content, maximum dry density and frost heaving properties of FRGSF were studied by means of compaction and frost heaving tests. Results show that the maximum dry density of the FRGSF increases first and then decreases with an increase of fines content, namely there is an optimum fines content for easy compaction. The method of surface-vibratory instrument is fit for coarse-grained soils, and wet state of coarse-grained soil is in favor of compaction. Considering the relationship of fines content with maximum dry density and the frost heaving ratio of FRGSF, the fines content should be limited to within the range of 9%-10%, so that the frost heaving ratio is less than 1%, and the FRGSF is easily compacted. Water supply is proved to be an important factor influencing the amount of frost heaving of FRGSF. We also conclude that in the field, it is imperative to control waterproofing and drainage measures.

Trends of Regional Precipitation and Their Control Mechanisms during 1979–2013

Trends in precipitation are critical to water resources. Considerable uncertainty remains concerning the trends of regional precipitation in response to global warming and their controlling mechanisms. Here, we use an interannual difference method to derive trends of regional precipitation from GPCP （Global Precipitation Climatology Project） data and MERRA （Modern- Era Retrospective Analysis for Research and Applications） reanalysis in the near-global domain of 60~ S-60~N during a major global warming period of 1979-2013. We find that trends of regional annual precipitation are primarily driven by changes in the top 30% heavy precipitation events, which in turn are controlled by changes in precipitable water in response to global warming, i.e., by thermodynamic processes. Significant drying trends are found in most parts of the U.S. and eastern Canada, the Middle East, and eastern South America, while significant increases in precipitation occur in northern Australia, southern Africa, western India and western China. In addition, as the climate warms there are extensive enhancements and expansions of the three major tropical precipitation centers-the Maritime Continent, Central America, and tropical Africa-leading to the observed widening of Hadley cells and a significant strengthening of the global hydrological cycle.

Controlling Factors of Organic Nanopore Development: A Case Study on Marine Shale in the Middle and Upper Yangtze Region, South China

The Upper Ordovician Wufeng-Lower Silurian Longmaxi and the Lower Cambrian Qiongzhusi shales are the major targets for shale gas exploration and development in China.Although the two organic-rich shales share similar distribution ranges and thicknesses,they exhibit substantially different exploration and development results.This work analyzed the nanopore structures of the shale reservoirs in this region.Pore development of 51 shale samples collected from various formations and locations was compared using the petromineralogical,geochemical,structural geological and reservoir geological methods.The results indicate that the reservoir space in these shales is dominated by organic pores and the total pore volume of micropores,mesopores,macropores in different tectonic areas and formations show different trends with the increase of TOC.It is suggested that organic pores of shale can be well preserved in areas with simple structure and suitable preservation conditions,and the shale with smaller maximum ancient burial depth and later hydrocarbongeneration-end-time is also more conducive to pore preservation.Organic pore evolution models are established,and they are as follows:①Organic matter pore development stage,②Early stage of organic matter pore destruction,and③late stage of organic matter pore destruction.The areas conducive to pore development are favorable for shale gas development.Research results can effectively guide the optimization and evaluation of favorable areas of shale gas.

Control of Facies and Potential on Jurassic Hydrocarbon Accumulation and Prediction of Favorable Targets in the Hinterland Region of the Junggar Basin

Exploration practices show that the Jurassic System in the hinterland region of the Junggar Basin has a low degree of exploration but huge potential, however the oil/gas accumulation rule is very complicated, and it is difficult to predict hydrocarbon-bearing properties. The research indicates that the oil and gas is controlled by structure facies belt and sedimentary system distribution macroscopically, and hydrocarbon-bearing properties of sand bodies are controlled by lithofacies and petrophysical facies microscopically. Controlled by ancient and current tectonic frameworks, most of the discovered oil and gas are distributed in the delta front sedimentary system of a palaeo-tectonic belt and an ancient slope belt. Subaqueous branch channels and estuary dams mainly with medium and fine sandstone are the main reservoirs and oil production layers, and sand bodies of high porosity and high permeability have good hydrocarbon-bearing properties; the facies controlling effect shows a reservoir controlling geologic model of relatively high porosity and permeability. The hydrocarbon distribution is also controlled by relatively low potential energy at the high points of local structure macroscopically, while most of the successful wells are distributed at the high points of local structure, and the hydrocarbon-bearing property is good at the place of relatively low potential energy; the hydrocarbon distribution is in close connection with faults, and the reservoirs near the fault in the region of relatively low pressure have good oil and gas shows; the distribution of lithologic reservoirs at the depression slope is controlled by the distribution of sand bodies at positions of relatively high porosity and permeability. The formation of the reservoir of the Jurassic in the Junggar Basin shows characteristics of favorable facies and low-potential coupling control, and among the currenffy discovered reservoirs and industrial hydrocarbon production wells, more than 90% are developed within the scope of facies- potential index FPI〉0.5, while the FPI and oil saturation of the discovered reservoir and unascertained traps have relatively good linear correlation. By establishing the relation model between hydrocarbon- bearing properties of traps and FPI, totally 43 favorable targets are predicted in four main target series of strata and mainly distributed in the Badaowan Formation and the Sangonghe Formation, and the most favorable targets include the north and east of the Shinan Sag, the middle and south of the Mobei Uplift, Cai-35 well area of the Cainan Oilfield, and North-74 well area of the Zhangbei fault-fold zone.

Role of 3'-untranslated region translational control in cancer development, diagnostics and treatment

The messenger RNA 3'-untranslated region(3'UTR)plays an important role in regulation of gene expres-sion on the posttranscriptional level. The 3'UTR con-trols gene expression via orchestrated interactionbetween the structural components of mRNAs(cis-ele-ment) and the specific trans-acting factors(RNA bind-ing proteins and non-coding RNAs). The crosstalk ofthese factors is based on the binding sequences and/or direct protein-protein interaction, or just functionalinteraction. Much new evidence that has accumulatedsupports the idea that several RNA binding factors canbind to common mRNA targets: to the non-overlappingbinding sites or to common sites in a competitive fash-ion. Various factors capable of binding to the sameRNA can cooperate or be antagonistic in their actions.The outcome of the collective function of all factorsbound to the same mRNA 3'UTR depends on manycircumstances, such as their expression levels, affinity to the binding sites, and localization in the cell, which can be controlled by various physiological conditions. Moreover, the functional and/or physical interactions of the factors binding to 3'UTR can change the character of their actions. These interactions vary during the cell cycle and in response to changing physiological condi-tions. Abnormal functioning of the factors can lead to disease. In this review we will discuss how alterations of these factors or their interaction can affect cancer development and promote or enhance the malignant phenotype of cancer cells. Understanding these altera-tions and their impact on 3'UTR-directed posttran-scriptional gene regulation will uncover promising new targets for therapeutic intervention and diagnostics. We will also discuss emerging new tools in cancer di-agnostics and therapy based on 3'UTR binding factors and approaches to improve them.

A New Region-of-interest Coding Method to Control the Relative Quality of Progressive Decoded Images

Based on the ideas of controlling relative quality and rearranging bitplanes, a new ROI coding method for JPEG2000 was proposed, which shifts and rearranges bitplanes in units of bitplane groups. It can code arbitrary shaped ROI without shape coding, and reserve almost arbitrary percent of background information. It also can control the relative quality of progressive decoded images. In addition, it is easy to be implemented and has low computational cost.

Shallow Genetic Structure of Pholis fangi in Bohai Sea and Yellow Sea Inferred from mt DNA Control Region

Pholis fangi is an ecologically important fish species inhabiting Chinese coastal waters of Yellow Sea and Bohai Sea. To investigate the genetic diversity and population genetic structure of P. fangi, a fragment of 487 bp in the first hypervariable region (HVR-1) of the mitochondrial DNA (mtDNA) control region was sequenced for 181 individuals collected from Bohai Sea and Yel- low Sea. A total of 18 polymorphic sites were detected, which defined 25 haplotypes. A moderate level of haplotype diversity (h = 0.7052) and a low level of nucleotide diversity (π= 0.0028) were detected. Both the phylogenetic tree and the haplotype network showed no significant genealogical structure difference among sampling locations. Pairwise FST comparison and hierarchical mo- lecular variance analysis (AMOVA) revealed that no significant genetic structure difference existed throughout the investigated re- gions, suggesting a high gene exchange among different populations. The results of neutrality test and mismatch distribution analysis indicated that a late Pleistocene population expansion (38000 127000 years ago) happened. Seasonal schooling migration may con- tribute to the genetically homogeneous population structure of the species.