here are limitations in using the seasonal rainfall total in studies of Monsoon rainfall climatology. A correlation analysis of the individual station seasonal rainfall with all India seasonal mean rainfall has been m...here are limitations in using the seasonal rainfall total in studies of Monsoon rainfall climatology. A correlation analysis of the individual station seasonal rainfall with all India seasonal mean rainfall has been made. After taking the significance test (strictly up to 5% level) the stations which are significantly correlated have been considered in this study in normal, flood and drought years respectively. Analysis of seasonal rainfall data of 50 stations spread over a period of 41 years suggests that a linear relationship fits better than the logarithmic relationship when seasonal rainfall versus number of rainy days is studied. The linear relationship is also found to be better in the case of seasonal rainfall versus mean daily intensity.展开更多
Nano-volt magnetic resonance sounding(MRS) signals are sufficiently weak so that during the actual measurement, they are affected by environmental electromagnetic noise, leading to inaccuracy of the extracted characte...Nano-volt magnetic resonance sounding(MRS) signals are sufficiently weak so that during the actual measurement, they are affected by environmental electromagnetic noise, leading to inaccuracy of the extracted characteristic parameters and hindering effective inverse interpretation. Considering the complexity and non-homogeneous spatial distribution of environmental noise and based on the theory of adaptive noise cancellation, a model system for noise cancellation using multi-reference coils was constructed to receive MRS signals. The feasibility of this system with theoretical calculation and experiments was analyzed and a modified sigmoid variable step size least mean square(SVSLMS) algorithm for noise cancellation was presented. The simulation results show that, the multi-reference coil method performs better than the single one on both signal-to-noise ratio(SNR) improvement and signal waveform optimization after filtering, under the condition of different noise correlations in the reference coils and primary detecting coils and different SNRs. In particular, when the noise correlation is poor and the SNR<0, the SNR can be improved by more than 8 dB after filtering with multi-reference coils. And the average fitting errors for initial amplitude and relaxation time are within 5%. Compared with the normalized least mean square(NLMS) algorithm and multichannel Wiener filter and processing field test data, the effectiveness of the proposed method is verified.展开更多
Density and elastic modulus change ratios are introduced to describe the sound velocity of submarine sediment. The density change ratio is a composite parameter describing the sound velocity. It is expressed by three ...Density and elastic modulus change ratios are introduced to describe the sound velocity of submarine sediment. The density change ratio is a composite parameter describing the sound velocity. It is expressed by three physical parameters: porosity, solid phase density and seawater density. The elastic modulus change ratio is also a composite parameter of sound velocity. It is expressed by three physical parameters, including porosity, solid phase modulus and seawater bulk modulus. The sound velocity formula can be developed into a Taylor polyno- mial formula of these two composite parameters. The change in the two composite parameters constitutes the sound velocity surface, which contains the complete information regarding ve- locity properties and sediment characteristics. The one-parameter velocity formula is a curve on the velocity surface. Each porosity-velocity empirical formula, which represents various sea locations and conditions, is transformed to a standard form. This result is the product of a reference velocity and a modulation function. Comparisons of the numerical calculation and measurements show that the derived modulation functions yield similar results. The difference between the velocity formula derived in this paper and the Wood velocity formula is due to the elastic modulus models.展开更多
The basic idea of multi-class classification is a disassembly method,which is to decompose a multi-class classification task into several binary classification tasks.In order to improve the accuracy of multi-class cla...The basic idea of multi-class classification is a disassembly method,which is to decompose a multi-class classification task into several binary classification tasks.In order to improve the accuracy of multi-class classification in the case of insufficient samples,this paper proposes a multi-class classification method combining K-means and multi-task relationship learning(MTRL).The method first uses the split method of One vs.Rest to disassemble the multi-class classification task into binary classification tasks.K-means is used to down sample the dataset of each task,which can prevent over-fitting of the model while reducing training costs.Finally,the sampled dataset is applied to the MTRL,and multiple binary classifiers are trained together.With the help of MTRL,this method can utilize the inter-task association to train the model,and achieve the purpose of improving the classification accuracy of each binary classifier.The effectiveness of the proposed approach is demonstrated by experimental results on the Iris dataset,Wine dataset,Multiple Features dataset,Wireless Indoor Localization dataset and Avila dataset.展开更多
Advanced processing of lung sound (LS) recording is a significant means to separate heart sounds (HS) and combined low frequency noise from instruments (NI), with saving its characteristics. This paper proposes a new ...Advanced processing of lung sound (LS) recording is a significant means to separate heart sounds (HS) and combined low frequency noise from instruments (NI), with saving its characteristics. This paper proposes a new method of LS filtering which separates HS and NI simultaneously. It focuses on the application of least mean squares (LMS) algorithm with adaptive noise cancelling (ANC) technique. The second step of the new method is to modulate the reference input r1(n) of LMS-ANC to acquiesce combining HS and NI signals. The obtained signal is removed from primary signal (original lung sound recording-LS). The original signal is recorded from subjects and derived HS from it and it is modified by a band pass filter. NI is simulated by generating approximately periodic white gaussian noise (WGN) signal. The LMS-ANC designed algorithm is controlled in order to determine the optimum values of the order L and the coefficient convergence μ. The output results are measured using power special density (PSD), which has shown the effectiveness of our suggested method. The result also has shown visual difference PSD (to) normal and abnormal LS recording. The results show that the method is a good technique for heart sound and noise reduction from lung sounds recordings simultaneously with saving LS characteristics.展开更多
The purpose of this paper is to broaden the knowledge of mean difference and,<span><span><span style="font-family:;" "=""> </span></span></span><span sty...The purpose of this paper is to broaden the knowledge of mean difference and,<span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">in particular, of an important distribution model known as Tukey lambda, which is generally used to choose a model to fit data.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">We have obtained compact formulas, which are not yet reported in literature, of mean deviation and mean difference related to the said distribution model.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">These results made it possible to analyze the relationships among variability indexes, namely standard deviation, mean deviation and mean difference, regarding Tukey lambda model.</span></span></span>展开更多
Purpose:This study aimed to examine the reliability and validity of load-velocity(L-V)relationship variables obtained through the 2-point method using different load combinations and velocity variables.Methods:Twenty ...Purpose:This study aimed to examine the reliability and validity of load-velocity(L-V)relationship variables obtained through the 2-point method using different load combinations and velocity variables.Methods:Twenty men performed 2 identical sessions consisting of 2 countermovement jumps against 4 external loads(20 kg,40 kg,60 kg,and80 kg)and a heavy squat against a load linked to a mean velocity(MV)of 0.55 m/s(load_(0.55)).The L-V relationship variables(load-axis intercept(L_(0)),velocity-axis intercept(v_(0)),and area under the L-V relationship line(A_(line)))were obtained using 3 velocity variables(MV,mean propulsive velocity(MPV),and peak velocity)by the multiple-point method including(20-40-60-80-load_(0.55))and excluding(20-40-60-80)the heavy squat,as well as from their respective 2-point methods(20-load_(0.55)and 20-80).Results:The L-V relationship variables were obtained with an acceptable reliability(coefncient of variation(CV)≤7.30%;intra-class correlation coefficient>0.63).The reliability of L_(0)and v_(0)was comparable for both methods(CV_(ratio)(calculated as higher value/lower value):1.11-1.12),but the multiple-point method provided Al_(ine)with a greater reliability(CV_(ratio)=1.26).The use of a heavy squat provided the L-V relationship variables with a comparable or higher reliability than the use of a heavy countermovement jump load(CV_(ratio):1.06-1.19).The peak velocity provided the load-velocity relationship variables with the greatest reliability(CV_(ratio):1.15-1.86)followed by the MV(CV_(ratio):1.07-1.18),and finally the MPV.The 2-point methods only revealed an acceptable validity for the MV and MPV(effect size≤0.19;Pearson s product-moment correlation coefficient≥0.96;Lin's concordance correlation coefficient≥0.94).Conclusion:The 2-point method obtained from a heavy squat load and MV or MPV is a quick,safe,and reliable procedure to evaluate the lower-body maximal neuromuscular capacities through the L-V relationship.展开更多
Despite its apparently simple genetics,cystic fibrosis(CF) is a rather complex genetic disease.A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator(CFTR) gene to t...Despite its apparently simple genetics,cystic fibrosis(CF) is a rather complex genetic disease.A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator(CFTR) gene to the clinical manifestations originates an uncertain genotype- phenotype relationship.A major determinant of this uncertainty is the incomplete knowledge of the CFTR mutated genotypes,due to the high number of CFTR mutations and to the higher number of their combinations in trans and in cis.Also the very limited knowledge of functional effects of CFTR mutated alleles severely impairs our diagnostic and prognostic ability.The final phenotypic modulation exerted by CFTR modifier genes and interactome further complicates the framework.The next generation sequencing approach is a rapid,lowcost and high-throughput tool that allows a near complete structural characterization of CFTR mutated genotypes,as well as of genotypes of several other genes cooperating to the final CF clinical manifestations.This powerful method perfectly complements the new personalized therapeutic approach for CF.Drugs active on specific CFTR mutational classes are already available for CF patients or are in phase 3 trials.A complete genetic characterization has been becoming crucial for a correct personalized therapy.However,the need of a functional classification of each CFTR mutation potently arises.Future big efforts towards an ever more detailed knowledge of both structural and functional CFTR defects,coupled to parallel personalized therapeutic interventions decisive for CF cure can be foreseen.展开更多
目的利用360°全方向24和36声源测试设备,初步探讨健听中青年和健听老年前期-老年人水平声源定位特点。方法选取2021年4月至2021年9月中国人民解放军总医院耳鼻喉科收治的43例健听成年受试者为研究对象,其中男性22例,女性21例;根据...目的利用360°全方向24和36声源测试设备,初步探讨健听中青年和健听老年前期-老年人水平声源定位特点。方法选取2021年4月至2021年9月中国人民解放军总医院耳鼻喉科收治的43例健听成年受试者为研究对象,其中男性22例,女性21例;根据年龄分为中青年组(21~49岁)20例和老年前期-老年组(50~72岁)23例。两组分别给予纯音听阈测试、全方向24声源(间隔15°)和36声源(间隔10°)水平声源定位(sound localization,SL)能力评估。给声强度60 dB HL,给声刺激为1 kHz啭音,通过计算均方根误差(root mean square,RMS)、平均绝对误差(mean absolutely error,MAE)等评估受试者的声源定位能力。结果24声源老年前期-老年组MAE、RMS均值高于中青年组的MAE、RMS均值,差异有统计学意义(P<0.05);36声源老年前期-老年组MAE、RMS高于中青年组的MAE、RMS,差异无统计学意义(P>0.05)。24声源和36声源前场MAE和RMS均高于后场的MAE和RMS,前后场的MAE和RMS比较,差异有统计学意义(P<0.01);左右场的MAE、RMS比较,差异无统计学意义(P>0.05)。24声源前后混淆比例为7.73%,36声源前后混淆比例为15.42%;24声源和36声源均为正前方的声源定位准确度最差;老年前期-老年组前后混淆的比例高于中青年组,差异无统计学意义(P>0.05)。结论健听老年前期-老年人全方向24声源和36声源水平定位能力,相比健听中青年组有所下降。左右场的定位准确度高,前后场的定位准确度低,正前方定位准确度最低。全方向水平声源定位能力的测试结果与扬声器数量有关,且反应趋势具有一致性。展开更多
文摘here are limitations in using the seasonal rainfall total in studies of Monsoon rainfall climatology. A correlation analysis of the individual station seasonal rainfall with all India seasonal mean rainfall has been made. After taking the significance test (strictly up to 5% level) the stations which are significantly correlated have been considered in this study in normal, flood and drought years respectively. Analysis of seasonal rainfall data of 50 stations spread over a period of 41 years suggests that a linear relationship fits better than the logarithmic relationship when seasonal rainfall versus number of rainy days is studied. The linear relationship is also found to be better in the case of seasonal rainfall versus mean daily intensity.
基金Projects(41204079,41504086)supported by the National Natural Science Foundation of ChinaProject(20160101281JC)supported by the Natural Science Foundation of Jilin Province,ChinaProjects(2016M590258,2015T80301)supported by the Postdoctoral Science Foundation of China
文摘Nano-volt magnetic resonance sounding(MRS) signals are sufficiently weak so that during the actual measurement, they are affected by environmental electromagnetic noise, leading to inaccuracy of the extracted characteristic parameters and hindering effective inverse interpretation. Considering the complexity and non-homogeneous spatial distribution of environmental noise and based on the theory of adaptive noise cancellation, a model system for noise cancellation using multi-reference coils was constructed to receive MRS signals. The feasibility of this system with theoretical calculation and experiments was analyzed and a modified sigmoid variable step size least mean square(SVSLMS) algorithm for noise cancellation was presented. The simulation results show that, the multi-reference coil method performs better than the single one on both signal-to-noise ratio(SNR) improvement and signal waveform optimization after filtering, under the condition of different noise correlations in the reference coils and primary detecting coils and different SNRs. In particular, when the noise correlation is poor and the SNR<0, the SNR can be improved by more than 8 dB after filtering with multi-reference coils. And the average fitting errors for initial amplitude and relaxation time are within 5%. Compared with the normalized least mean square(NLMS) algorithm and multichannel Wiener filter and processing field test data, the effectiveness of the proposed method is verified.
基金supported by the National Natural Science Foundation of China(41176034,41476028)the Natural Science Foundation of Guangdong,China(10151009001000052)the Key Laboratory of Marine Mineral Resources,Ministry of Land and Resources(KLMMR-2014-B-03)
文摘Density and elastic modulus change ratios are introduced to describe the sound velocity of submarine sediment. The density change ratio is a composite parameter describing the sound velocity. It is expressed by three physical parameters: porosity, solid phase density and seawater density. The elastic modulus change ratio is also a composite parameter of sound velocity. It is expressed by three physical parameters, including porosity, solid phase modulus and seawater bulk modulus. The sound velocity formula can be developed into a Taylor polyno- mial formula of these two composite parameters. The change in the two composite parameters constitutes the sound velocity surface, which contains the complete information regarding ve- locity properties and sediment characteristics. The one-parameter velocity formula is a curve on the velocity surface. Each porosity-velocity empirical formula, which represents various sea locations and conditions, is transformed to a standard form. This result is the product of a reference velocity and a modulation function. Comparisons of the numerical calculation and measurements show that the derived modulation functions yield similar results. The difference between the velocity formula derived in this paper and the Wood velocity formula is due to the elastic modulus models.
基金supported by the National Natural Science Foundation of China(61703131 61703129+1 种基金 61701148 61703128)
文摘The basic idea of multi-class classification is a disassembly method,which is to decompose a multi-class classification task into several binary classification tasks.In order to improve the accuracy of multi-class classification in the case of insufficient samples,this paper proposes a multi-class classification method combining K-means and multi-task relationship learning(MTRL).The method first uses the split method of One vs.Rest to disassemble the multi-class classification task into binary classification tasks.K-means is used to down sample the dataset of each task,which can prevent over-fitting of the model while reducing training costs.Finally,the sampled dataset is applied to the MTRL,and multiple binary classifiers are trained together.With the help of MTRL,this method can utilize the inter-task association to train the model,and achieve the purpose of improving the classification accuracy of each binary classifier.The effectiveness of the proposed approach is demonstrated by experimental results on the Iris dataset,Wine dataset,Multiple Features dataset,Wireless Indoor Localization dataset and Avila dataset.
文摘Advanced processing of lung sound (LS) recording is a significant means to separate heart sounds (HS) and combined low frequency noise from instruments (NI), with saving its characteristics. This paper proposes a new method of LS filtering which separates HS and NI simultaneously. It focuses on the application of least mean squares (LMS) algorithm with adaptive noise cancelling (ANC) technique. The second step of the new method is to modulate the reference input r1(n) of LMS-ANC to acquiesce combining HS and NI signals. The obtained signal is removed from primary signal (original lung sound recording-LS). The original signal is recorded from subjects and derived HS from it and it is modified by a band pass filter. NI is simulated by generating approximately periodic white gaussian noise (WGN) signal. The LMS-ANC designed algorithm is controlled in order to determine the optimum values of the order L and the coefficient convergence μ. The output results are measured using power special density (PSD), which has shown the effectiveness of our suggested method. The result also has shown visual difference PSD (to) normal and abnormal LS recording. The results show that the method is a good technique for heart sound and noise reduction from lung sounds recordings simultaneously with saving LS characteristics.
文摘The purpose of this paper is to broaden the knowledge of mean difference and,<span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">in particular, of an important distribution model known as Tukey lambda, which is generally used to choose a model to fit data.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">We have obtained compact formulas, which are not yet reported in literature, of mean deviation and mean difference related to the said distribution model.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">These results made it possible to analyze the relationships among variability indexes, namely standard deviation, mean deviation and mean difference, regarding Tukey lambda model.</span></span></span>
文摘Purpose:This study aimed to examine the reliability and validity of load-velocity(L-V)relationship variables obtained through the 2-point method using different load combinations and velocity variables.Methods:Twenty men performed 2 identical sessions consisting of 2 countermovement jumps against 4 external loads(20 kg,40 kg,60 kg,and80 kg)and a heavy squat against a load linked to a mean velocity(MV)of 0.55 m/s(load_(0.55)).The L-V relationship variables(load-axis intercept(L_(0)),velocity-axis intercept(v_(0)),and area under the L-V relationship line(A_(line)))were obtained using 3 velocity variables(MV,mean propulsive velocity(MPV),and peak velocity)by the multiple-point method including(20-40-60-80-load_(0.55))and excluding(20-40-60-80)the heavy squat,as well as from their respective 2-point methods(20-load_(0.55)and 20-80).Results:The L-V relationship variables were obtained with an acceptable reliability(coefncient of variation(CV)≤7.30%;intra-class correlation coefficient>0.63).The reliability of L_(0)and v_(0)was comparable for both methods(CV_(ratio)(calculated as higher value/lower value):1.11-1.12),but the multiple-point method provided Al_(ine)with a greater reliability(CV_(ratio)=1.26).The use of a heavy squat provided the L-V relationship variables with a comparable or higher reliability than the use of a heavy countermovement jump load(CV_(ratio):1.06-1.19).The peak velocity provided the load-velocity relationship variables with the greatest reliability(CV_(ratio):1.15-1.86)followed by the MV(CV_(ratio):1.07-1.18),and finally the MPV.The 2-point methods only revealed an acceptable validity for the MV and MPV(effect size≤0.19;Pearson s product-moment correlation coefficient≥0.96;Lin's concordance correlation coefficient≥0.94).Conclusion:The 2-point method obtained from a heavy squat load and MV or MPV is a quick,safe,and reliable procedure to evaluate the lower-body maximal neuromuscular capacities through the L-V relationship.
文摘Despite its apparently simple genetics,cystic fibrosis(CF) is a rather complex genetic disease.A lot of variability in the steps of the path from the cystic fibrosis transmembrane conductance regulator(CFTR) gene to the clinical manifestations originates an uncertain genotype- phenotype relationship.A major determinant of this uncertainty is the incomplete knowledge of the CFTR mutated genotypes,due to the high number of CFTR mutations and to the higher number of their combinations in trans and in cis.Also the very limited knowledge of functional effects of CFTR mutated alleles severely impairs our diagnostic and prognostic ability.The final phenotypic modulation exerted by CFTR modifier genes and interactome further complicates the framework.The next generation sequencing approach is a rapid,lowcost and high-throughput tool that allows a near complete structural characterization of CFTR mutated genotypes,as well as of genotypes of several other genes cooperating to the final CF clinical manifestations.This powerful method perfectly complements the new personalized therapeutic approach for CF.Drugs active on specific CFTR mutational classes are already available for CF patients or are in phase 3 trials.A complete genetic characterization has been becoming crucial for a correct personalized therapy.However,the need of a functional classification of each CFTR mutation potently arises.Future big efforts towards an ever more detailed knowledge of both structural and functional CFTR defects,coupled to parallel personalized therapeutic interventions decisive for CF cure can be foreseen.
文摘目的利用360°全方向24和36声源测试设备,初步探讨健听中青年和健听老年前期-老年人水平声源定位特点。方法选取2021年4月至2021年9月中国人民解放军总医院耳鼻喉科收治的43例健听成年受试者为研究对象,其中男性22例,女性21例;根据年龄分为中青年组(21~49岁)20例和老年前期-老年组(50~72岁)23例。两组分别给予纯音听阈测试、全方向24声源(间隔15°)和36声源(间隔10°)水平声源定位(sound localization,SL)能力评估。给声强度60 dB HL,给声刺激为1 kHz啭音,通过计算均方根误差(root mean square,RMS)、平均绝对误差(mean absolutely error,MAE)等评估受试者的声源定位能力。结果24声源老年前期-老年组MAE、RMS均值高于中青年组的MAE、RMS均值,差异有统计学意义(P<0.05);36声源老年前期-老年组MAE、RMS高于中青年组的MAE、RMS,差异无统计学意义(P>0.05)。24声源和36声源前场MAE和RMS均高于后场的MAE和RMS,前后场的MAE和RMS比较,差异有统计学意义(P<0.01);左右场的MAE、RMS比较,差异无统计学意义(P>0.05)。24声源前后混淆比例为7.73%,36声源前后混淆比例为15.42%;24声源和36声源均为正前方的声源定位准确度最差;老年前期-老年组前后混淆的比例高于中青年组,差异无统计学意义(P>0.05)。结论健听老年前期-老年人全方向24声源和36声源水平定位能力,相比健听中青年组有所下降。左右场的定位准确度高,前后场的定位准确度低,正前方定位准确度最低。全方向水平声源定位能力的测试结果与扬声器数量有关,且反应趋势具有一致性。