Treatment of Special Renal Colic with Ureteroscope and Holmium YAG Laser

Objective To investigate the method of emergent relief of special renal colic and treatment of ureter diseases causing renal colic. Methods By analyzing 63 cases of special renal colic treated with ureteroscope and Holmium YAG laser. Results 61 cases of renal colic were relieved in a short period of time and the original ureter diseases causing renal colic were cured. Conclusion Special renal colic could be treated with ureteroscope and Holmium YAG laser in a quick and effective manner.

Renal Colic: Epidemiological, Clinical Etiological and Therapeutic Aspects at the Urology Department of the National Reference General Hospital of N’Djamena (Chad)

Introduction: Renal colic is a medico-surgical emergency in which complicated forms could progress to renal failure and nonfunctional kidney. The objective of our study is to describe the epidemiological, diagnostic and therapeutic aspects of renal colic at the urology department of the NGRH. Methods: This was a prospective study involving 101 patients followed up for renal colic. The study spanned from July 2015 to July 2016 at the urology department of the NGRH. Results: A total of 101 patients suffering from renal colic were enrolled in the study giving a prevalence of 5.1%. The mean age was 38.89 years with a standard deviation of 14.5 years and a sex ratio of 1:3. Flank or lumbar pain of crushing type (45.5%), constant and of severe intensity (61.4%) were the most frequent clinical characteristics. The plain abdominal radiography (Kidney-Ureter-Bladder) coupled with ultrasonography had a 100% sensitivity for the etiological diagnosis of renal colic. Urinary lithiasis was the most frequent cause with 73.3%. Uroculture revealed a urinary tract infection in 44 patients (43.6%). The most frequent germ isolated on the culture was Escherichia coli (27.7%). Renal function was abnormal in 34 patients (33.7%). Medical treatment was composed of analgesics, NSAIDs and antispasmodic representing 93.1%. Percutaneous nephrostomy was performed in 6.9%. Pyelolithotomy was the most frequently performed surgical procedure and was done in 11 patients that are 39.3%. Fifty seven patients (56.4%) got healed without sequelae;6 cases (5.9%) of recurrence and 2 deaths (2%) were recorded. Conclusion: Renal colic is common in urology. Urinary lithiasis was the major cause in our series. Renal function could be endangered in case of late management.

Electroacupuncture Treatment of 50 Patients with Renal Colic

Treated 50 cases of renal colic with electroacupuncture and compared the results with those in two control groups. Total effective rate in the treatment group, control group Ⅰ and control group Ⅱ was 98.0%,90.0% and 92.0% respectively.

Urological Emergencies at the University Hospital of Brazzaville: Epidemiological, Clinical, and Therapeutic Aspects

Introduction: Urological emergencies play a significant role in the medical and surgical activity of a urology department. The objective of this study was to determine the hospital prevalence of urological emergencies at the University Hospital of Brazzaville (CHUB), identify the different pathologies requiring urgent care, and list the various therapeutic methods. Patients and methods: A retrospective study of patients admitted to the medical and surgical emergencies department of CHUB over a 5-year period. Patient records admitted and treated for a urological emergency were included. The variables studied were the frequency of urological emergencies, patient age at admission, gender, nature of the emergency, and various therapeutic options. Results: Urological emergencies accounted for 4.3% of all medical and surgical emergencies. The mean age was 57 ± 28 years with a range of 3 to 93 years. The male-to-female ratio was 7.1. The most common conditions were urinary retention (54.67%), hematuria (17.20%), and renal colic (8.13%). Therapeutically, surgical urinary drainage was dominated by cystostomy. Conclusion: Urological emergencies are infrequent at the University Hospital of Brazzaville. Their management is often delayed.

酮咯酸氨丁三醇与氢溴酸山莨菪碱在输尿管结石导致的急性肾绞痛患者中的应用效果比较

目的 比较酮咯酸氨丁三醇与氢溴酸山莨菪碱在输尿管结石导致的急性肾绞痛患者中的应用效果。方法 回顾性分析2020年1月至2022年1月于北京市海淀医院急诊外科就诊的166例输尿管结石导致的急性肾绞痛患者的临床资料,采用随机数字法将研究对象分为对照组(肌内注射氢溴酸山莨菪碱,81例)和观察组(肌内注射酮咯酸氨丁三醇,85例)。比较分析两组患者用药前以及用药后30 min、1 h、4 h的疼痛程度,用药后30 min的临床疗效,用药期间的不良反应发生情况。结果 与用药前比较,两组患者用药后30 min、1 h、4 h的视觉模拟评分法(VAS)评分均降低,差异均有统计学意义(P<0.05)。用药前,两组患者的VAS评分比较差异无统计学意义(P>0.05);用药后30 min、1 h、4 h,观察组患者的VAS评分均低于对照组,差异均有统计学意义(P<0.05)。用药后30 min,观察组患者的总有效率高于对照组,差异有统计学意义(P<0.05)。观察组患者用药期间的不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论 在输尿管结石导致的急性肾绞痛患者中,与肌内注射氢溴酸山莨菪碱比较,肌内注射酮咯酸氨丁三醇的镇痛效果更好,且不良反应更少。

针灸治疗急性肾绞痛临床选穴组方规律研究

【目的】通过数据挖掘技术分析临床针灸治疗急性肾绞痛选穴组方的规律。【方法】检索中国知网期刊全文数据库(CNKI)、万方学术期刊全文数据库(Wanfang)、维普中文科技期刊数据库(VIP)、PubMed数据库已经公开发表并收录的关于针灸治疗急性肾绞痛的临床文献,通过严格筛选,采用Microsoft Excel、SPSS 26.0、IBM SPSS Modeler 15.0软件以及其中的Apriori算法对纳入文献进行信息挖掘与分析。【结果】纳入110篇关于针灸治疗急性肾绞痛的临床文献,统计针灸处方共110条,涉及使用腧穴共59个,其中,肾俞、阿是穴和三阴交的使用频次最高;常用经脉为足太阳膀胱经、足太阴脾经、足阳明胃经;腧穴主要分布在下肢与腰背部;从选用穴位类型来看,五输穴、背俞穴、下合穴为首选;双穴组合配伍中,肾俞、阿是穴组合支持度最高;三穴组合配伍中,肾俞、三阴交、阿是穴组合支持度最高;核心腧穴组合是肾俞与阿是穴组合。【结论】针灸治疗急性肾绞痛的腧穴选择和组方是有规律可循的,所总结的选穴和组方规律能够为其临床治疗和科学研究提供参考。

间苯三酚与山莨菪碱在急诊肾绞痛患者中的应用效果比较

目的探讨间苯三酚与山莨菪碱在急诊肾绞痛患者中的应用效果比较。方法选取2022年3月至2023年9月华中科技大学协和深圳医院急诊收治的86例肾绞痛患者作为研究对象,按随机数字表法将其分为对照组(43例)和观察组(43例)。对照组采用双氯芬酸钠缓释片+山莨菪碱治疗,研究组采用双氯芬酸钠缓释片+间苯三酚治疗。比较两组临床疗效、疼痛程度[视觉模拟评分法(VAS)评分]、疼痛缓解时间、镇痛起效时间、不良反应发生率、24 h复发率。结果研究组总有效率高于对照组,差异有统计学意义(P<0.05);研究组治疗后VAS评分低于对照组,差异有统计学意义(P<0.05);研究组疼痛缓解时间、镇痛起效时间均短于对照组,差异有统计学意义(P<0.05);研究组不良反应总发生率低于对照组,差异有统计学意义(P<0.05);研究组24 h复发率低于对照组,差异有统计学意义(P<0.05)。结论间苯三酚作为一种新型解痉止痛药,与山莨菪碱相比起效快,解痉止痛效果显著,且副作用较小,安全性更高,具有临床应用价值。

右旋布洛芬栓对输尿管结石所致肾绞痛的临床疗效研究

目的探究右旋布洛芬栓对输尿管结石所致肾绞痛的临床疗效及安全性。方法选取64例确诊为输尿管结石所致肾绞痛患者,以随机数字表法分为对照组和观察组,每组32例。两组均给予氢溴酸山莨菪碱治疗,在此基础上,对照组给予双氯芬酸钠栓治疗,观察组给予右旋布洛芬栓治疗。比较两组患者临床疗效、症状缓解时间(疼痛开始缓解时间、疼痛完全缓解时间)、血清中炎症因子[血清白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、白细胞介素-1β(IL-1β)]、不良反应发生情况。结果对照组总有效率为96.88%,观察组总有效率为90.63%。两组患者临床总有效率比较无统计学差异(χ^(2)=1.067,P=0.302>0.05)。对照组疼痛开始缓解时间为(18.73±3.12)min,观察组疼痛开始缓解时间为(12.67±2.91)min,两组相比具有统计学差异(t=8.035,P=0.000<0.05)。对照组疼痛完全缓解时间为(34.12±3.04)min,观察组疼痛完全缓解时间为(24.62±4.81)min,两组相比具有统计学差异(t=9.444,P=0.000<0.05)。与治疗前相比,两组患者治疗后血清中IL-6、TNF-α、IL-1β水平均明显降低(P<0.05);治疗后,与对照组的(4.67±0.37)、(20.01±2.01)、(2.86±0.15)pg/ml相比,观察组血清中IL-6(4.10±0.15)pg/ml、TNF-α(16.25±3.17)pg/ml、IL-1β(2.11±0.17)pg/ml显著降低(P<0.05)。两组患者不良反应发生率比较无统计学差异(χ^(2)=0,P=1>0.05)。结论对于输尿管结石所致肾绞痛患者应用右旋布洛芬栓在疼痛症状改善、降低机体炎症反应方面优于双氯芬酸钠栓,且安全性可控,值得临床推广。

四金石灵膏联合帕瑞昔布治疗湿热瘀阻型输尿管结石伴肾绞痛的效果研究

目的分析四金石灵膏联合帕瑞昔布治疗湿热瘀阻型输尿管结石伴肾绞痛的临床效果。方法116例湿热瘀阻型输尿管结石伴肾绞痛患者,按随机数字表法分为对照组及观察组,每组58例。对照组采用注射用帕瑞昔布钠治疗,观察组采用注射用帕瑞昔布钠联合四金石灵膏治疗。比较两组治疗前后的中医证候积分、视觉模拟评分法(VAS)评分及24 h尿生化指标[尿酸(UA)、尿草酸(UOA)、尿钙(U-Ca)],不良反应发生情况,疗效。结果治疗后,两组腰腹疼痛、小便艰涩、口干欲饮、大便干结中医证候积分均下降,且观察组腰腹疼痛、小便艰涩、口干欲饮、大便干结中医证候积分分别为(0.20±0.05)、(0.27±0.04)、(0.34±0.04)、(0.34±0.04)分,均低于对照组的(0.77±0.11)、(0.91±0.08)、(0.89±0.21)、(0.38±0.05)分,有统计学差异(P<0.05)。治疗后,两组VAS评分下降,且观察组VAS评分(1.22±0.23)分低于对照组的(3.21±0.67)分,有统计学差异(P<0.05)。治疗后,两组24 h尿生化指标UA、U-Ca、UOA均下降,且观察组24 h尿生化指标UA、U-Ca、UOA分别为(2.80±0.95)、(3.27±1.32)、(0.22±0.08)mmol/d,均低于对照组的(3.63±1.03)、(4.64±0.19)、(0.39±0.14)mmol/d,有统计学差异(P<0.05)。治疗后,观察组不良反应发生率低于对照组,但差异无统计学意义(P>0.05)。观察组总有效率96.55%高于对照组的82.76%,有统计学差异(P<0.05)。结论四金石灵膏联合帕瑞昔布治疗湿热瘀阻型输尿管结石伴肾绞痛患者,可快速缓解疼痛,利于结石排出体外,改善其生命健康质量,值得推广。

失笑散加味联合西医治疗结石性肾绞痛的临床效果

目的探讨失笑散加味联合西医治疗结石性肾绞痛的临床效果。方法选取2020年4月—2022年2月云南省大理白族自治州中医医院急诊科诊治的60例结石性肾绞痛患者为研究对象。根据治疗方案的不同均分2组,各30例。以常规西药治疗为对照组,观察组在对照组的基础上加用失笑散加味治疗。比较2组临床疗效、疼痛评分、结石清除率、结石排出时间和不良反应发生情况。结果观察组的总有效率为96.67%,高于对照组的80.00%,差异有统计学意义(P<0.05)。治疗后,观察组的疼痛评分为(1.54±0.23)分,低于对照组的(2.83±0.36)分,差异有统计学意义(P<0.05)。观察组结石清除率(90.00%)高于对照组(66.67%),观察组结石排出时间为(5.87±2.16)d,短于对照组的(8.49±2.83)d,差异有统计学意义(P<0.05)。2组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论失笑散加味联合西药治疗结石性肾绞痛可以缓解患者疼痛,促进结石排出,避免疼痛再发,且具有较好的安全性。

腕踝针结合乌芍祛痛散治疗肾绞痛临床研究

目的:观察腕踝针结合乌芍祛痛散治疗肾绞痛的疗效。方法:60例随机分为观察组和对照组各30例,观察组用腕踝针及乌芍祛痛散,对照组给予帕瑞昔布钠治疗。结果:观察组治疗后0.5、1、24h的VAS评分,对照组治疗后1、24h的VAS评分均降低(P<0.05)。观察组的疼痛缓解时间短于对照组(P<0.05),不良反应发生率低于对照组(P<0.05)。结论:腕踝针及乌芍祛痛散治疗肾绞痛能够快速缓解肾绞痛,不良反应少。

壮医点穴疗法配合指压邱氏穴治疗结石性肾绞痛的临床研究

目的深度挖掘壮医点穴疗法配合指压邱氏穴治疗结石性肾绞痛的临床优势,临床观察该治疗方法确切的治疗效果,为进一步探索研究及推广该治疗方法的临床应用打下坚实基础。方法将结石性肾绞痛患者116例随机分为观察组41例、治疗1组38例、治疗2组37例,观察组采用壮医点穴疗法配合指压邱氏穴,治疗1组使用复方双氯芬酸钠注射液,治疗2组采用壮医点穴疗法配合指压邱氏穴联合使用复方双氯芬酸钠注射液,三组分别从止痛起效时间、止痛疗效、24小时复发率、不良反应等方面作比较。结果观察组与治疗1组比较,观察组在止痛起效时间(3.17±0.92、18.21±2.82)、治疗后VAS评分(1.37±1.43、3.21±1.74)、显效率(87.80%、50.00%)、总有效率(95.12.%、76.32%)占有明显的优势,具有显著差异性(P<0.05);治疗2组24小时复发率明显低于观察组及治疗1组(P<0.05);观察组未发现不良反应。结论壮医点穴疗法配合指压邱氏穴治疗结石性肾绞痛具有疗效好、不良反应少等优势,同时联合镇痛药物的治疗,可进一步提高止痛效果,明显降低疼痛复发率,值得临床推广应用。

中医特色护理干预对泌尿系结石肾绞痛患者的影响

目的探讨中医特色护理干预对泌尿系结石肾绞痛患者的影响。方法便利选取2021年1月—2023年5月威海市中医院收治的86例泌尿系结石肾绞痛患者为研究对象,以随机数表法分组,对照组(n=43)实施常规护理,观察组(n=43)则采用中医特色护理干预,比较两组患者干预前后疼痛评分与焦虑/抑郁自评量表评分,以匹兹堡睡眠质量指数评估患者睡眠质量,并调查患者满意度。结果干预后6、12、24、48 h,观察组患者的疼痛视觉模拟法(Visual Analogue Scale,VAS)评分分别为(3.05±1.01)分、(2.86±0.74)分、(2.55±0.61)分、(2.23±0.55)分,均低于对照组,差异有统计学意义(t=5.357、4.390、4.864、5.894,P均<0.05)。干预后,观察组患者的焦虑、抑郁评分低于对照组,差异有统计学意义(P均<0.05)。干预后,观察组匹兹堡睡眠质量指数各维度评分均较对照组低,差异有统计学意义(P均<0.05)。观察组满意度较对照组高,差异有统计学意义(P<0.05)。结论对泌尿系结石肾绞痛患者采用中医特色护理干预效果确切,能减轻患者疼痛,改善其负性情绪与睡眠质量,并可提高护理满意度。

全息刮痧联合中药烫熨对泌尿系结石性肾绞痛的护理效果

目的探讨全息刮痧联合中药烫熨对泌尿系结石性肾绞痛患者的护理效果。方法选取2022年5月—2023年9月萍乡市中医院收治的泌尿系结石性肾绞痛患者60例,采用随机数字表法分为两组,每组30例。对照组予常规护理,观察组在此基础上予全息刮痧联合中药烫熨治疗,观察两组疼痛数字评定量表(NRS)评分、疼痛缓解时间、临床疗效及护理满意度。结果干预后15 min、30 min及60 min,观察组NRS评分均低于对照组(P<0.05)。观察组肾绞痛开始缓解时间及完全消失时间均短于对照组(P<0.05)。观察组干预总有效率为93.33%(28/30),高于对照组的70.00%(21/30)(P<0.05)。观察组护理总满意度为100.00%(30/30),高于对照组的76.67%(23/30)(P<0.05)。结论全息刮痧联合中药烫熨干预泌尿系结石性肾绞痛患者,护理效果较明显,满意度较好,应用价值较高。

Effectiveness of Using Renalof®in the Elimination of Kidney Stones under 10 mm Located in the Renal-Ureteral Tract

Background: In view of the high recurrence of kidney stones in patients, the search for less aggressive, preventive treatments has become increasingly essential. Renalof® offers a phytotherapy alternative. Due to its diuretic and kidney stone demineralisation properties, it has been widely used in this patient population, disintegrating and eliminating calcium oxalate and struvite kidney stones painlessly in the genitourinary system. Methods: A Phase II, randomised, prospective, observational, single-blind study with two treatment arms was conducted in order to determine the efficacy of this alternative therapy: a total of 155 patients were enrolled, 120 were assigned to a Renalof® treatment group and 35 to the placebo group. All were over 18 years of age, of both genders, diagnosed with kidney stones of under 10 mm in diameter, present along the entire renal-ureteral-vesicular tract, diagnosed by ultrasound and renal CAT scan. Divided into two study arms, 120 were administered a dosage of a single 325 mg capsule of the Renalof® product half an hour before the two main meals for 3 months. The presence of kidney stones in any part of the renal-ureteral tract was assessed at monthly consultations using one of the above-mentioned diagnostic tools. Results: Study results show a high rate of effectiveness with Renalof®, finding up to a 65% expulsion rate (78 patients) in the first 8 weeks of treatment, compared to 11.4% (4 patients) in the placebo control group, P < 0.001. It is likely a longer follow-up period would be necessary in patients with kidney stones of 10 mm in diameter or larger than the period applied in the study. Discussion: We strongly recommend the inclusion of this product in kidney stone disease management protocols, especially for patients with kidney stones under 10 mm in diameter, where high response and effectiveness have been observed. Thus, it should be evaluated to reduce surgical treatment costs, as well as those for possible colic episodes and other associated complications.

腕踝针在急性肾绞痛治疗中的应用价值

目的探讨腕踝针治疗在急性肾绞痛患者中的应用价值。方法选取2022年10月—2023年9月威海市中医院收治的92例泌尿系结石肾绞痛患者,按照乱数表法随机分为对照组与针刺组,各46例。对照组予以常规西药治疗,针刺组在其基础上增加腕踝针治疗,两组均持续治疗1周。比较两组临床疗效,治疗前后中医证候评分(腰腹绞痛、小便涩痛、排尿不畅),治疗前与治疗后15 min、30 min、60 min疼痛程度[视觉模拟评分法(VAS)],以及等待治疗时间、不良反应发生率、护理满意度。结果治疗后,针刺组临床总有效率高于对照组(P<0.05);两组中医证候评分均较治疗前降低,且针刺组低于对照组,差异有统计学意义(P<0.05);治疗后15 min、30 min、60 min,两组VAS评分均较治疗前降低,且针刺组均低于同期对照组,差异有统计学意义(P<0.05,P<0.01);针刺组等待治疗时间、不良反应总发生率均低于对照组(P<0.01,P<0.05);针刺组护理总满意度高于对照组(P<0.05)。结论腕踝针治疗在急性肾绞痛患者中应用价值较高,能缩短患者等待治疗时间,改善临床症状与疼痛程度,安全性良好,并获得较高的患者满意度。

探讨指压邱氏穴对肾绞痛的疗效评估及对炎性因子的影响

目的:探讨指压邱氏穴对肾绞痛的疗效评估及对炎性因子的影响。方法:选择2022年6月—2023年7月在罗湖区中医院院就诊的肾绞痛患者70例,按照电脑软件随机法分为两组,每组35例。对照组接受常规一线用药治疗,观察组在对照组的基础上联合指压邱氏穴治疗,观察两组情况。结果:治疗前,两组VAS评分和炎症因子(IL-6)评分没有显著差异,不具有统计学意义(P>0.05);两组治疗后5 min、30 min、60 min的VAS评分均低于治疗前,且观察组VAS评分低于对照组,差异有统计学意义(P<0.05);两组治疗后炎症因子(1L-6)评分均低于治疗前,且观察组炎症因子(1L-6)评分低于对照组,差异有统计学意义(P<0.05);观察组的疼痛缓解快于对照组,差异有统计学意义(P<0.05);两组不良反应差异没有统计学意义(P>0.05);观察组的临床疗效优于对照组,差异有统计学意义(P<0.05)。结论:采用指压邱氏穴治疗肾绞痛具有迅速起效的优势,能够快速实现镇痛效果,在临床值得推广。

Wrist-ankle acupuncture combined with pain nursing for the treatment of urinary calculi with acute pain

BACKGROUND Urological calculi often cause renal colic,which is characterized by paroxysmal or persistent severe pain in the upper abdomen or lumbar region.Development of methods to quickly relieve these pain symptoms has garnered clinical attention.Wrist-ankle acupuncture is a type of floating acupuncture therapy administered at selected points in the carpal and ankle areas,and it has good pain-relieving effects.We used wrist-ankle acupuncture combined with pain nursing for pain intervention in patients with renal calculi to confirm its application and safety.AIM To study the effect of wrist-ankle acupuncture combined with pain nursing in the treatment of urinary calculi with acute pain.METHODS Eighty-two patients with urinary calculi with acute pain as the first symptom followed at our hospital from November 2019 to June 2021 were enrolled in the study and classified into two groups according to the odd and even numbers of the visit sequences,each with 41 cases.The control group received a routine nursing intervention and intramuscular injection of nonsteroidal anti-inflammatory drugs,whereas the observation group received pain management nursing and wrist-ankle acupuncture.Subsequently,the pain-relieving effect was compared between the two groups.RESULTS The score on the visual analog scale(VAS)at 24,48,and 72 h postintervention was decreased in both groups compared with the baseline data;moreover,the observation group scored significantly lower than the control group on the VAS at each time point after the intervention(P<0.05).The clinical efficacy at 24 h postintervention was not significantly different between the two groups(P>0.05).In turn,the pain recurrence rate at 72 h postintervention was lower in the observation group compared with the control group(P<0.05).Finally,the nursing satisfaction rate in the observation group was significantly higher than that observed in the control group(P<0.05).No serious adverse reactions occurred during the treatment and the safety of treatment was high in both groups.CONCLUSION Wrist-ankle acupuncture combined with pain nursing for treating urolithiasis with acute pain effectively alleviated the degree of pain and reduced the recurrence rate,which was worthy of clinical application.

生理盐水穴位注射联合中药封包治疗肾绞痛的临床分析

目的研究生理盐水穴位注射联合中药封包治疗肾绞痛的临床效果。方法选取甘肃省中医院于2020年1月—2021年2月收治的60例肾绞痛患者,采用双色球随机法分组,对照组(30例)和观察组(30例),对照组肾绞痛患者采用生理盐水穴位注射治疗,观察组肾绞痛患者采用生理盐水穴位注射联合中药封包治疗。对比两组肾绞痛患者的各项临床指标。结果观察组肾绞痛患者总有效率为93.33%,高于对照组的70.00%(P<0.05)。观察组肾绞痛患者疼痛缓解时间短于对照组(P<0.05)。观察组肾绞痛患者治疗后0.5、1 h视觉模拟评分法(visual analogue scale,VAS)低于对照组(P<0.05)。观察组治疗后3、7 d的健康调查量表36(36-item short form health survey,short f orm 36,SF-36)评分高于对照组(P<0.05)。观察组肾绞痛患者血尿、排尿困难、头晕、呕吐总发生率为3.33%,低于对照组的20.00%(P<0.05)。结论生理盐水穴位注射联合中药封包治疗肾绞痛的临床效果显著优于单用生理盐水穴位注射治疗,因此联用中药封包治疗更具推广价值。