This paper is a continuation of recent work by Guo-Xiang-Zheng[10].We deduce the sharp Morrey regularity theory for weak solutions to the fourth order nonhomogeneous Lamm-Rivière equation △^{2}u=△(V▽u)+div(w▽...This paper is a continuation of recent work by Guo-Xiang-Zheng[10].We deduce the sharp Morrey regularity theory for weak solutions to the fourth order nonhomogeneous Lamm-Rivière equation △^{2}u=△(V▽u)+div(w▽u)+(▽ω+F)·▽u+f in B^(4),under the smallest regularity assumptions of V,ω,ω,F,where f belongs to some Morrey spaces.This work was motivated by many geometrical problems such as the flow of biharmonic mappings.Our results deepens the Lp type regularity theory of[10],and generalizes the work of Du,Kang and Wang[4]on a second order problem to our fourth order problems.展开更多
We consider a generalized form of the porous medium equation where the porosity ϕis a function of time t: ϕ=ϕ(x,t): ∂(ϕS)∂t−∇⋅(k(S)∇S)=Q(S).In many works, the porosity ϕis either assumed to be independent of (or to de...We consider a generalized form of the porous medium equation where the porosity ϕis a function of time t: ϕ=ϕ(x,t): ∂(ϕS)∂t−∇⋅(k(S)∇S)=Q(S).In many works, the porosity ϕis either assumed to be independent of (or to depend very little of) the time variable t. In this work, we want to study the case where it does depend on t(and xas well). For this purpose, we make a change of unknown function V=ϕSin order to obtain a saturation-like (advection-diffusion) equation. A priori estimates and regularity results are established for the new equation based in part on what is known from the saturation equation, when ϕis independent of the time t. These results are then extended to the full saturation equation with time-dependent porosity ϕ=ϕ(x,t). In this analysis, we make explicitly the dependence of the various constants in the estimates on the porosity ϕby the introduced transport vector w, through the change of unknown function. Also we do not assume zero-flux boundary, but we carry the analysis for the case Q≡0.展开更多
This paper examines the occurrence regularity and comprehensive prevention and control techniques for sunflower downy mildew.It provides a detailed discussion of the pathogens,symptoms,and associated risks,as well as ...This paper examines the occurrence regularity and comprehensive prevention and control techniques for sunflower downy mildew.It provides a detailed discussion of the pathogens,symptoms,and associated risks,as well as the transmission pathways,underlying causes,and prevention and control techniques related to sunflower downy mildew.The aim is to offer valuable references and technical guidance for the effective management of this disease.展开更多
[Objectives]The paper was to understand the occurrence and damage regularity of the invasive plant Mikania micrantha in Huadu District of Guangzhou.[Methods]The damage status of M.micranthFa in different forest lands ...[Objectives]The paper was to understand the occurrence and damage regularity of the invasive plant Mikania micrantha in Huadu District of Guangzhou.[Methods]The damage status of M.micranthFa in different forest lands and its annual growth dynamics were investigated by field investigation.[Results]With the change of canopy density from low to high,the occurrence degree of M.micrantha changed from high to low.The occurrence degree of M.micrantha in different forest land types was:abandoned orchard>wasteland>roadside greenbelt>waterside>forest edge>normally managed orchard.[Conclusions]M.micrantha enters the rapid growth period from March to May in spring,with the growth rate gradually slowing down after June.The result provides a theoretical basis and practical guidance for the prevention and control of M.micrantha.展开更多
This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of suff...This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of sufficient regularity of boundary conditions and coefficients, as long as the angle is sufficiently small, the regularity of the solution to the mixed boundary value problem of the second-order elliptic equation can reach any order.展开更多
Hyperbolic conservation laws arise in the context of continuum physics,and are mathematically presented in differential form and understood in the distributional(weak)sense.The formal application of the Gauss-Green th...Hyperbolic conservation laws arise in the context of continuum physics,and are mathematically presented in differential form and understood in the distributional(weak)sense.The formal application of the Gauss-Green theorem results in integral balance laws,in which the concept of flux plays a central role.This paper addresses the spacetime viewpoint of the flux regularity,providing a rigorous treatment of integral balance laws.The established Lipschitz regularity of fluxes(over time intervals)leads to a consistent flux approximation.Thus,fully discrete finite volume schemes of high order may be consistently justified with reference to the spacetime integral balance laws.展开更多
[ Objective ] The research aimed to discuss the occurrence regularity of apple early defoliation disease and control effects of fungicides in west Sichuan plateau. [ Method ] Apple early defoliation disease in west Si...[ Objective ] The research aimed to discuss the occurrence regularity of apple early defoliation disease and control effects of fungicides in west Sichuan plateau. [ Method ] Apple early defoliation disease in west Sichuan plateau was systematically investigated during 2009 and 2011, and the control effects of different fungicides during different spraying periods were studied. [ Result] The species of pathogen mainly was Marssonina ma/i ( P. Henn), accounting for 32.5%, Phyl-losticta Pirina Sa accounted for 29.9%, and Alternaria mali Roberts accounted for 25.7%. The field fluctuation regularity was as follows : the disease generally be- gan in the mid-May and ended in early and middle October with only one damage peak during the whole year, the fluctuation had positive correlation with rainfall ( R2 =0.891 8 * * ). Control test showed that 40% flusilazole had the best control effect (86.5%), which was best to apply after anthesis. [ Conclusion ] The paper provided theoretical basis for the effective control against apple early defoliation disease.展开更多
The changes in the evolvement patterns of surface electromyography(EMG)signals during both static and dynamic fatiguing contractions are studied.The main finding is that the EMG signal tends to be more and more regu...The changes in the evolvement patterns of surface electromyography(EMG)signals during both static and dynamic fatiguing contractions are studied.The main finding is that the EMG signal tends to be more and more regular as muscle fatigues.An increase in the summation of all the regular evolvement patterns denoted by Dreg reflects such a tendency.Compared with traditional measurements,Dreg shows less variability among subjects when characterizing a fatigue process.In addition,the calculation of Dreg in the time domain is free from the restrictions disturbing those of spectral parameters.The detection of an increase in the EMG regularity not only proposes a new and easy way to inspect changes in EMG during the fatigue process,but also provides strong supports to estimate muscle fatigue by means of nonlinear analysis methods such as entropy and complexity measures.The detection method of signal regularity can also be applied to other physiological signals.展开更多
The common phenomenon of uneven headway in bus service is explored based on the automatic vehicle location (AVL) data of Route 2 in Yichun City of Jiangxi province from 6:00 to 9:00 in the morning. The headway reg...The common phenomenon of uneven headway in bus service is explored based on the automatic vehicle location (AVL) data of Route 2 in Yichun City of Jiangxi province from 6:00 to 9:00 in the morning. The headway regularity of two stages 6: 00--7:00 and 7: 00--9:00 is comparatively analyzed, and it is found that both the traffic conditions and the passenger demand affect headway regularity. A bus arrival model, which assumes that the dwell time of a bus is linear in headway, is built to probe the effect of scheduled headway, and the model is simulated by Matlab. The simulation results reveal that the departure intervals and fluctuations affect headway regularity. Longer intervals and less fluctuation mean higher regularity of headway. And, the fluctuation has a more obvious influence on headway regularity than the interval. Controlling the fluctuations of scheduled headway can effectively raise the regularity of headway and improve the level of public transport service.展开更多
With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systemati...With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systematical monitoring and field survey, rice blast resistance identification, physiologic races of rice blast monitoring, and meteorological data analysis were performed to study the occurrence and epidemic region division, precise demarcation and occurrence and epidemic regularity of rice blast in Nanchong City. This study first completed the epidemic region division and precise demarcation; first clarified the initial affection(beginning period) locations, occurrence characteristics, epidemic trends and characteristics; explicated the existence of four epidemic peak periods of rice blast in the field, where the damage areas of first peak period played a decisive role during the blast epidemic years; in late May, the cumulative occurrence areas and annual occurrence areas presented higher positive correlation with the correlation coefficient of 0.817;and established a prediction model of occurrence areas per year based on the disease field rate at the end of boot stages and the diseased plant rate at dough stages. The results of investigation on the impact factors investigation of blast disease in Nanchong in recent years suggested that the internal causes were the decrease or loss of blast resistance of the rice cultivars, as well as the increase of physiological races with strong resistance to rice blast and the emergence of new virulent physiologic varieties; the external causes were suitable temperature, too much rainy, and sunlight shortage. Between 2010 and 2015, the short-term forecast accuracy for rice blast in Nanchong was up to 100%, and medium-and long-term forecast accuracy was also up to 98% and 95%, respectively, which increased by 5-15% than that before 1997, thereby making the control effect of rice blast in Nanchong increased by 15-30%.展开更多
Objective] The study aimed to investigate the effects of primary and sec-ondary trunk girdling on the status and distribution regularity of nutrients in grape. [Method] Using grape cultivar ‘Rose Honey’ as the exper...Objective] The study aimed to investigate the effects of primary and sec-ondary trunk girdling on the status and distribution regularity of nutrients in grape. [Method] Using grape cultivar ‘Rose Honey’ as the experimental material, the ef-fects of primary and secondary trunk girdling on carbon and nitrogen nutrition, min-eral nutrition and nutrient distribution regularity in leaves and branches above the girdling wound and roots below the girdling wound were analyzed. [Result] Girdling could significantly increase non-structural carbohydrate content (such as soluble sugar and starch) in branches above the girdling wound, reduce soluble protein and total nitrogen contents, and significantly improve C/N ratio. Specifical y, the highest C/N ratio in primary girdling group and secondary girdling group was 9.04 and 5.35, respectively, but C/N ratio in control group was only 4.89 in the same period. Girdling not only significantly decreased the content of non-structural carbohydrates (such as soluble sugar and starch) in roots, but also significantly declined soluble protein and total nitrogen content, which also reduced C/N ratio in various degrees. Specifical y, the lowest C/N ratio in primary girdling group and secondary girdling group was 1.16 and 3.06, respectively, while that in control group was 3.15 in the same period. ln addition, primary girdling exerted much greater effects on carbon and nitrogen nutrition than secondary girdling. Moreover, girdling significantly de-creased the contents of phosphorus, potassium, ferrum and copper in grape leaves, branches and roots. Specifical y, primary girdling exerted greater effects on ferrum and copper contents in leaves and branches. The contents of ferrum and copper in the first batch of samples exhibited significant differences between primary girdling group and control group: ferrum content in leaves was 75.05 μg/g DW in primary girdling group and that in control group was 85.29 μg/g DW; ferrum content in branches was 76.45 ?g/g DW in primary girdling group and copper content was 7.82 μg/g DW, while ferrum and copper contents in control group were 95.96 and 10.74 μg/g DW, respectively. [Conclusion] This study provided the basis for accu-rately regulating tree nutrition and ensuring safe and effective use of girdling tech-nique in ‘Rose Honey’ production.展开更多
An algorithm named DPP is addressed.In it,a new model based on the concept of irregularity degree is founded to evaluate the regularity of cells.It generates the structure regularity of cells by exploiting the signal ...An algorithm named DPP is addressed.In it,a new model based on the concept of irregularity degree is founded to evaluate the regularity of cells.It generates the structure regularity of cells by exploiting the signal flow of circuit.Then,it converts the bit slice structure to parallel constraints to enable Q place algorithm.The design flow and the main algorithms are introduced.Finally,the satisfied experimental result of the tool compared with the Cadence placement tool SE is discussed.展开更多
We consider the following quasiconvex functional I(u)=∫ Gf(x,δu,D mu) d x where u is a vector valued function in W m,p (G),m>1 and p>2. The partial C m,a —regularity is proved fo...We consider the following quasiconvex functional I(u)=∫ Gf(x,δu,D mu) d x where u is a vector valued function in W m,p (G),m>1 and p>2. The partial C m,a —regularity is proved for minimizers of I(u) under weaker conditions.展开更多
BACKGROUND In recent years,many studies have shown that proteasome 26S subunit non-ATPase 6(PSMD6)plays an important role in the occurrence and development of malignant tumours.Unfortunately,there are no reports on th...BACKGROUND In recent years,many studies have shown that proteasome 26S subunit non-ATPase 6(PSMD6)plays an important role in the occurrence and development of malignant tumours.Unfortunately,there are no reports on the evaluation of the potential role of PSMD6 in hepatocellular carcinoma(HCC).AIM To comprehensively evaluate the overexpression pattern and clinical significance of PSMD6 in HCC tissues.METHODS This study integrated PSMD6 mRNA expression profiles from 4672 HCC and 3667 non-HCC tissues,along with immunohistochemical scores from 383 HCC and adjacent tissues,to assess PSMD6 overexpression in HCC.Clustered regularly interspaced short palindromic repeats knockout technology evaluated PSMD6’s essential role in HCC cell growth.Functional enrichment analysis explored the molecular mechanism of PSMD6 abnormalities in HCC.Drug sensitivity analysis and molecular docking analysed the effect of abnormal expression of PSMD6 on the drug sensitivity of HCC cells.RESULTS The results of 41 external and two internal datasets showed that PSMD6 mRNA(SMD=0.26,95%CI:0.09-0.42,P<0.05)and protein(SMD=2.85,95%CI:1.19-4.50,P<0.05)were significantly overexpressed in HCC tissues.The integrated analysis results showed that PSMD6 had a significant overexpression pattern in HCC tissues(SMD=0.40,95%CI:0.15-0.66,P<0.05).PSMD6 knockout inhibited HCC cell growth(chronos scores<-1).Functional enrichment implicated ribosome biogenesis and RNA splicing.Significant enrichment of signalling pathways such as RNA degradation,ribosomes,and chemical carcinogenesis—reactive oxygen species.Drug sensitivity analysis and a molecular docking model showed that high expression of PSMD6 was associated with the tolerance of HCC cells to drugs such as ML323,sepantronium bromide,and GDC0810.Overexpressed PSMD6 effectively distinguished HCC tissues(AUC=0.75,95%CI:0.71-0.79).CONCLUSION This study was the first to discover that PSMD6 was overexpressed in HCC tissues.PSMD6 is essential for the growth of HCC cells and may be involved in ribosome biogenesis and RNA splicing.展开更多
基金supported by the National Natural Science Foundation of China(12271296,12271195).
文摘This paper is a continuation of recent work by Guo-Xiang-Zheng[10].We deduce the sharp Morrey regularity theory for weak solutions to the fourth order nonhomogeneous Lamm-Rivière equation △^{2}u=△(V▽u)+div(w▽u)+(▽ω+F)·▽u+f in B^(4),under the smallest regularity assumptions of V,ω,ω,F,where f belongs to some Morrey spaces.This work was motivated by many geometrical problems such as the flow of biharmonic mappings.Our results deepens the Lp type regularity theory of[10],and generalizes the work of Du,Kang and Wang[4]on a second order problem to our fourth order problems.
文摘We consider a generalized form of the porous medium equation where the porosity ϕis a function of time t: ϕ=ϕ(x,t): ∂(ϕS)∂t−∇⋅(k(S)∇S)=Q(S).In many works, the porosity ϕis either assumed to be independent of (or to depend very little of) the time variable t. In this work, we want to study the case where it does depend on t(and xas well). For this purpose, we make a change of unknown function V=ϕSin order to obtain a saturation-like (advection-diffusion) equation. A priori estimates and regularity results are established for the new equation based in part on what is known from the saturation equation, when ϕis independent of the time t. These results are then extended to the full saturation equation with time-dependent porosity ϕ=ϕ(x,t). In this analysis, we make explicitly the dependence of the various constants in the estimates on the porosity ϕby the introduced transport vector w, through the change of unknown function. Also we do not assume zero-flux boundary, but we carry the analysis for the case Q≡0.
基金Supported by Wujiaqu City Science and Technology Program Project of the Sixth Division(2214)Science and Technology Research Project in Key Areas of the Xinjiang Production and Construction Corps(2024AB014)+4 种基金Financial Program of the Ninth Division(2024JS007)"Strengthening Youth"Science and Technology Innovation Backbone Talent Program of the Xinjiang Production and Construction Corps(2023007-06)Key R&D Program of Xinjiang Autonomous Region(2023B02008-1)Excellence Youth Program of the Xinjiang Production and Construction CorpsEarmarked Fund for China Agriculture Research System(CARS-16).
文摘This paper examines the occurrence regularity and comprehensive prevention and control techniques for sunflower downy mildew.It provides a detailed discussion of the pathogens,symptoms,and associated risks,as well as the transmission pathways,underlying causes,and prevention and control techniques related to sunflower downy mildew.The aim is to offer valuable references and technical guidance for the effective management of this disease.
文摘[Objectives]The paper was to understand the occurrence and damage regularity of the invasive plant Mikania micrantha in Huadu District of Guangzhou.[Methods]The damage status of M.micranthFa in different forest lands and its annual growth dynamics were investigated by field investigation.[Results]With the change of canopy density from low to high,the occurrence degree of M.micrantha changed from high to low.The occurrence degree of M.micrantha in different forest land types was:abandoned orchard>wasteland>roadside greenbelt>waterside>forest edge>normally managed orchard.[Conclusions]M.micrantha enters the rapid growth period from March to May in spring,with the growth rate gradually slowing down after June.The result provides a theoretical basis and practical guidance for the prevention and control of M.micrantha.
文摘This paper considers the regularity of solutions to mixed boundary value problems in small-angle regions for elliptic equations. By constructing a specific barrier function, we proved that under the assumption of sufficient regularity of boundary conditions and coefficients, as long as the angle is sufficiently small, the regularity of the solution to the mixed boundary value problem of the second-order elliptic equation can reach any order.
基金supported by the NSFC(Nos.11771054,12072042,91852207)the Sino-German Research Group Project(No.GZ1465)the National Key Project GJXM92579.
文摘Hyperbolic conservation laws arise in the context of continuum physics,and are mathematically presented in differential form and understood in the distributional(weak)sense.The formal application of the Gauss-Green theorem results in integral balance laws,in which the concept of flux plays a central role.This paper addresses the spacetime viewpoint of the flux regularity,providing a rigorous treatment of integral balance laws.The established Lipschitz regularity of fluxes(over time intervals)leads to a consistent flux approximation.Thus,fully discrete finite volume schemes of high order may be consistently justified with reference to the spacetime integral balance laws.
基金Supported by Comprehensive Test Station in West Sichuan Plateau for National Apple's Industrial Technology System ( CARS-28)~~
文摘[ Objective ] The research aimed to discuss the occurrence regularity of apple early defoliation disease and control effects of fungicides in west Sichuan plateau. [ Method ] Apple early defoliation disease in west Sichuan plateau was systematically investigated during 2009 and 2011, and the control effects of different fungicides during different spraying periods were studied. [ Result] The species of pathogen mainly was Marssonina ma/i ( P. Henn), accounting for 32.5%, Phyl-losticta Pirina Sa accounted for 29.9%, and Alternaria mali Roberts accounted for 25.7%. The field fluctuation regularity was as follows : the disease generally be- gan in the mid-May and ended in early and middle October with only one damage peak during the whole year, the fluctuation had positive correlation with rainfall ( R2 =0.891 8 * * ). Control test showed that 40% flusilazole had the best control effect (86.5%), which was best to apply after anthesis. [ Conclusion ] The paper provided theoretical basis for the effective control against apple early defoliation disease.
基金The National Basic Research Program of China(973Program)(No.2005CB724303)the Natural Science Foundation of Shanghai(No.09ZR1409600)the Shanghai Leading Academic Discipline Project(No.B412)
文摘The changes in the evolvement patterns of surface electromyography(EMG)signals during both static and dynamic fatiguing contractions are studied.The main finding is that the EMG signal tends to be more and more regular as muscle fatigues.An increase in the summation of all the regular evolvement patterns denoted by Dreg reflects such a tendency.Compared with traditional measurements,Dreg shows less variability among subjects when characterizing a fatigue process.In addition,the calculation of Dreg in the time domain is free from the restrictions disturbing those of spectral parameters.The detection of an increase in the EMG regularity not only proposes a new and easy way to inspect changes in EMG during the fatigue process,but also provides strong supports to estimate muscle fatigue by means of nonlinear analysis methods such as entropy and complexity measures.The detection method of signal regularity can also be applied to other physiological signals.
基金The National Basic Research Program of China(973 Program)(No.2012CB725402)the National Natural Science Foundation of China(No.50978057)Program of Scientific Innovation Research of College Graduate in Jiangsu Province(No.CXLX12_0108)
文摘The common phenomenon of uneven headway in bus service is explored based on the automatic vehicle location (AVL) data of Route 2 in Yichun City of Jiangxi province from 6:00 to 9:00 in the morning. The headway regularity of two stages 6: 00--7:00 and 7: 00--9:00 is comparatively analyzed, and it is found that both the traffic conditions and the passenger demand affect headway regularity. A bus arrival model, which assumes that the dwell time of a bus is linear in headway, is built to probe the effect of scheduled headway, and the model is simulated by Matlab. The simulation results reveal that the departure intervals and fluctuations affect headway regularity. Longer intervals and less fluctuation mean higher regularity of headway. And, the fluctuation has a more obvious influence on headway regularity than the interval. Controlling the fluctuations of scheduled headway can effectively raise the regularity of headway and improve the level of public transport service.
基金Supported by Notice on the First Batch of National Modern Agricultural Demonstration Zone by the Ministry of Agriculture([2010]22)the Research and Application Project for the Early Warning and Comprehensive Control of the Major Pests and Diseases for Main Grain and Oil Crops(N1997-ZC002)the Fundamental Research Funds for the Central Universities(XDJK2015C060,SWU114046,2362015xk04)~~
文摘With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systematical monitoring and field survey, rice blast resistance identification, physiologic races of rice blast monitoring, and meteorological data analysis were performed to study the occurrence and epidemic region division, precise demarcation and occurrence and epidemic regularity of rice blast in Nanchong City. This study first completed the epidemic region division and precise demarcation; first clarified the initial affection(beginning period) locations, occurrence characteristics, epidemic trends and characteristics; explicated the existence of four epidemic peak periods of rice blast in the field, where the damage areas of first peak period played a decisive role during the blast epidemic years; in late May, the cumulative occurrence areas and annual occurrence areas presented higher positive correlation with the correlation coefficient of 0.817;and established a prediction model of occurrence areas per year based on the disease field rate at the end of boot stages and the diseased plant rate at dough stages. The results of investigation on the impact factors investigation of blast disease in Nanchong in recent years suggested that the internal causes were the decrease or loss of blast resistance of the rice cultivars, as well as the increase of physiological races with strong resistance to rice blast and the emergence of new virulent physiologic varieties; the external causes were suitable temperature, too much rainy, and sunlight shortage. Between 2010 and 2015, the short-term forecast accuracy for rice blast in Nanchong was up to 100%, and medium-and long-term forecast accuracy was also up to 98% and 95%, respectively, which increased by 5-15% than that before 1997, thereby making the control effect of rice blast in Nanchong increased by 15-30%.
基金Supported by National Natural Science Foundation of China(31660559)Scientific Research Project of Kunming University(XJZZ1604)Key Disciplines(Ecology)Project of Yunnan Education Department~~
文摘Objective] The study aimed to investigate the effects of primary and sec-ondary trunk girdling on the status and distribution regularity of nutrients in grape. [Method] Using grape cultivar ‘Rose Honey’ as the experimental material, the ef-fects of primary and secondary trunk girdling on carbon and nitrogen nutrition, min-eral nutrition and nutrient distribution regularity in leaves and branches above the girdling wound and roots below the girdling wound were analyzed. [Result] Girdling could significantly increase non-structural carbohydrate content (such as soluble sugar and starch) in branches above the girdling wound, reduce soluble protein and total nitrogen contents, and significantly improve C/N ratio. Specifical y, the highest C/N ratio in primary girdling group and secondary girdling group was 9.04 and 5.35, respectively, but C/N ratio in control group was only 4.89 in the same period. Girdling not only significantly decreased the content of non-structural carbohydrates (such as soluble sugar and starch) in roots, but also significantly declined soluble protein and total nitrogen content, which also reduced C/N ratio in various degrees. Specifical y, the lowest C/N ratio in primary girdling group and secondary girdling group was 1.16 and 3.06, respectively, while that in control group was 3.15 in the same period. ln addition, primary girdling exerted much greater effects on carbon and nitrogen nutrition than secondary girdling. Moreover, girdling significantly de-creased the contents of phosphorus, potassium, ferrum and copper in grape leaves, branches and roots. Specifical y, primary girdling exerted greater effects on ferrum and copper contents in leaves and branches. The contents of ferrum and copper in the first batch of samples exhibited significant differences between primary girdling group and control group: ferrum content in leaves was 75.05 μg/g DW in primary girdling group and that in control group was 85.29 μg/g DW; ferrum content in branches was 76.45 ?g/g DW in primary girdling group and copper content was 7.82 μg/g DW, while ferrum and copper contents in control group were 95.96 and 10.74 μg/g DW, respectively. [Conclusion] This study provided the basis for accu-rately regulating tree nutrition and ensuring safe and effective use of girdling tech-nique in ‘Rose Honey’ production.
文摘An algorithm named DPP is addressed.In it,a new model based on the concept of irregularity degree is founded to evaluate the regularity of cells.It generates the structure regularity of cells by exploiting the signal flow of circuit.Then,it converts the bit slice structure to parallel constraints to enable Q place algorithm.The design flow and the main algorithms are introduced.Finally,the satisfied experimental result of the tool compared with the Cadence placement tool SE is discussed.
文摘We consider the following quasiconvex functional I(u)=∫ Gf(x,δu,D mu) d x where u is a vector valued function in W m,p (G),m>1 and p>2. The partial C m,a —regularity is proved for minimizers of I(u) under weaker conditions.
基金Supported by National Natural Science Foundation of China,No.82160762Guangxi Zhuang Autonomous Region Administration of Traditional Chinese Medicine Scientific Research Project,No.GXZYA20230267+2 种基金China Undergraduate Innovation and Entrepreneurship Training Program,No.S202410598060XChina Undergraduate Innovation and Entrepreneurship Training Program,No.X202410598360Future Academic Star of Guangxi Medical University,No.WLXSZX24074.
文摘BACKGROUND In recent years,many studies have shown that proteasome 26S subunit non-ATPase 6(PSMD6)plays an important role in the occurrence and development of malignant tumours.Unfortunately,there are no reports on the evaluation of the potential role of PSMD6 in hepatocellular carcinoma(HCC).AIM To comprehensively evaluate the overexpression pattern and clinical significance of PSMD6 in HCC tissues.METHODS This study integrated PSMD6 mRNA expression profiles from 4672 HCC and 3667 non-HCC tissues,along with immunohistochemical scores from 383 HCC and adjacent tissues,to assess PSMD6 overexpression in HCC.Clustered regularly interspaced short palindromic repeats knockout technology evaluated PSMD6’s essential role in HCC cell growth.Functional enrichment analysis explored the molecular mechanism of PSMD6 abnormalities in HCC.Drug sensitivity analysis and molecular docking analysed the effect of abnormal expression of PSMD6 on the drug sensitivity of HCC cells.RESULTS The results of 41 external and two internal datasets showed that PSMD6 mRNA(SMD=0.26,95%CI:0.09-0.42,P<0.05)and protein(SMD=2.85,95%CI:1.19-4.50,P<0.05)were significantly overexpressed in HCC tissues.The integrated analysis results showed that PSMD6 had a significant overexpression pattern in HCC tissues(SMD=0.40,95%CI:0.15-0.66,P<0.05).PSMD6 knockout inhibited HCC cell growth(chronos scores<-1).Functional enrichment implicated ribosome biogenesis and RNA splicing.Significant enrichment of signalling pathways such as RNA degradation,ribosomes,and chemical carcinogenesis—reactive oxygen species.Drug sensitivity analysis and a molecular docking model showed that high expression of PSMD6 was associated with the tolerance of HCC cells to drugs such as ML323,sepantronium bromide,and GDC0810.Overexpressed PSMD6 effectively distinguished HCC tissues(AUC=0.75,95%CI:0.71-0.79).CONCLUSION This study was the first to discover that PSMD6 was overexpressed in HCC tissues.PSMD6 is essential for the growth of HCC cells and may be involved in ribosome biogenesis and RNA splicing.