A systematic review of the efficacy of traditional Chinese medicine retention enema in the treatment of ulcerative colitis

The objective of this study is to summarize the efficacy and safety of traditional Chinese medicine(TCM)enema in the treatment of ulcerative colitis(UC).The randomized controlled trials on TCM enema intervention in the treatment of UC were searched in seven databases:PubMed,Embase,Web of Science,CBM,CNKI,Wanfang Database,and VIP Database from January 1,2013 to June 6,2022,and the data were analyzed using RevMan 5.3 software.A total of 18 studies involving 1514 UC patients were included.Meta analysis results showed that compared with conventional Western medicine,Chinese medicine enema had a significant effect on UC,and the clinical effective rate of the experimental group using Chinese medicine enema was 4.45 times that of the control group using conventional Western medicine(odds ratio=4.45,95%confidence interval[3.27,6.06]).Therefore,Chinese medicine enema is effective in the treatment of UC,and can significantly reduce related symptoms.

A Meta-Analysis of Treating Radiation Proctitis by Retention Enema with Integrated Traditional Chinese and Western Medicine

Objective:To systematically and objectively evaluate clinical efficacy of retention enema with integrated traditional Chinese and western medicine on radiation proctitis(RP).Methods:CNKI,WANFANG,VIP,CMB and foreign language databases like Embase,Central and Medline were searched.Search dates were from establishment of the databases until May 2020.Randomized controlled trials(RCTs)of retention enema with integrated traditional Chinese and western medicine for RP were retrieved.Two system reviewers selected literature materials,extracted literature data,and evaluated the quality of the literatures.RevMan 5.3 software was used for data analysis.Results:A total of 12 studies were included,including 941 patients.Meta-analysis results showed:Clinical efficacy in the retention enema group with integrated traditional Chinese and western medicine was better than that in the simple western medicine enema or blank enema group(OR=5.96,95%CI[5.50,14.29],P<0.00001).Improvement of abdominal pain in the retention enema group with integrated traditional Chinese and western medicine was better than that in the control group(MD=-0.57,95%CI[-0.72,-0.42],P<0.00001).Treatment for hematochezia in the retention enema group with integrated traditional Chinese and western medicine was better than that in the control group(MD=-0.55,95%CI[-0.69,-0.42],P<0.00001).Improvement of diarrhea in the retention enema group with integrated traditional Chinese and western medicine was better than that in the control group(MD=-0.69,95%CI[-0.91,-0.48],P<0.00001).KPS scores in the retention enema group with integrated traditional Chinese and western medicine were better than those in the control group(MD=11.91,95%CI[3.81,20.01],P<0.00001).Conclusion:Clinical efficacy of retention enema with integrated traditional Chinese and western medicine on RP is better than simple western medicine enema or blank enema.Due to the low quality of the included clinical literatures,it is necessary to carry out more deliberate,detailed,high-quality,randomized,double-blind,and multi-center RCTs in order to give more powerful demonstration on its clinical efficacy on RP.

Structural and functional characteristics of microbiota in oropharynx of sub-healthy children with gastrointestinal heat retention syndrome differentiated by traditional Chinese medicine

Objective:To explore the structural and functional characteristics of microbiota in oropharynx of subhealthy children with gastrointestinal heat retention syndrome(GHRS)differentiated by traditional Chinese medicine,and screen the biometric operational taxonomic units(OTUs)to assist the clinical diagnosis.Methods:We recruited children according to the“GHRS diagnostic scale”,collected their oropharyngeal swabs,and sequenced the 16 SrDNA V4 region.We described the bacterial structure with alpha-indexes,beta-distances,and relative abundances;moreover,we screened the differential genera/OTUs with Wilcoxon rank-sum test,Metagenome Seq analysis,and linear discriminant analysis effect size(LEf Se)analysis,in which biometric OTUs were selected to construct the receiver operating characteristic curve to verify the diagnostic value.The bacterial function was predicted with Kyoto Encyclopedia of Genes and Genomes pathways according to 16S rDNA gene by using Phylogenetic Investigation of Communities by Reconstruction of Unobserved States.Results:The study population was composed of 10 children with GHRS and 10 healthy control children.GHRS children were more likely to overeat(gluttony,P=.033).Alpha-indexes,such as Sobs,abundancebased coverage estimator,Bootstrap,and Qstat,were significantly higher in the GHRS group,while betadistances did not exhibit any significant intergroup differences.There were 9 differently distributed nonpredominant genera between the groups in Wilcoxon rank-sum test,as well as 13 non-predominant genera in Metagenome Seq analysis and 3 non-predominant OTUs in LEfSe analysis.OTU44 and OTU196 were used to construct the receiver operating characteristic curve,and the area under curve was 0.92.Predicted functions showed that pathways related to oxidative phosphorylation and carbon metabolism were enriched in healthy control samples,while the pathway related to renin secretion was remarkably enriched in GHRS samples.Conclusion:Unique oropharyngeal microbial structure and function were identified in GHRS children.OTU44 and OTU196 were specific OTUs,which could be used as biomarkers of GHRS to assist clinical diagnosis.

Feasibility and simulation model of a pilot scale membrane bioreactor for wastewater treatment and reuse from Chinese traditional medicine

The lack and pollution of water resource make wastewater reuse necessary. The pilot scale long-term tests for submerged membrane bioreactor were conducted to treat the effluents of anaerobic or aerobic treatment process for the high-strength Chinese traditional medicine wastewater. This article was focused on the feasibility of the wastewater treatment and reuse at shorter hydraulic retention time （HRT） of 5.0, 3.2 and 2.13 h. MLSS growth, membrane flux, vacuum values and chemical cleaning periods were also investigated. The experimental results of treating two-phase anaerobic treatment effluent demonstrated that the CODfilt was less than 100 mg/L when the influent COD was between 500-10000 mg/L at HRT of 5.0 h, which could satisfy the normal discharged standard in China. The experimental results to treat cross flow aerobic reactor effluent demonstrated that the average value of CODfilt was 17.28 mg/L when the average value of influent COD was 192.84 mg/L at HRT of 2.13 h during 106 d, which could completely meet the normal standard for water reuse. The maximum MLSS and MLVSS reached 24000 and 14500 mg/L at HRT of 3.2 h respectively. Membrane flux had maximal resume degrees of 94.7% at vacuum value of 0.02 MPa after cleaning. Chemical cleaning periods of membrane module were 150 d. A simulation model of operational parameters was also established based on the theory of back propagation neural network and linear regression of traditional mathematical model. The simulation model showed that the optimum operational parameters were suggested as follows： HRT was 5.0 h, SRT was 100 d, the range of COD loading rate was between 10.664-20.451 kg/（m3.d）, the range of MLSS was between 7543-13694 mg/L.

基于子午流注的气交灸法在脑卒中后气虚型尿潴留病人中的应用

目的:探讨基于子午流注的气交灸法治疗脑卒中后气虚型尿潴留病人的临床效果。方法:选取2022年1月—2023年1月在我院住院治疗的60例脑卒中后气虚型尿潴留病人,采用随机数字表法将其分为治疗组和对照组,各30例,对照组给予脑卒中后尿潴留护理常规护理,治疗组在对照组的基础上实施基于子午流注的气交灸法,比较两组治疗前、治疗2周后膀胱残余尿量、治疗后的临床疗效和满意度。结果:治疗2周后,治疗组膀胱残余尿量、临床疗效和满意度均优于对照组,差异有统计学意义(P<0.05)。结论:基于子午流注的气交灸法能有效减少脑卒中后气虚型尿潴留病人的残余尿量,改善临床疗效,提高病人满意度。

双黄溃结宁灌肠方治疗轻中度大肠湿热型溃疡性结肠炎临床观察

目的探讨双黄溃结宁灌肠方治疗轻中度溃疡性结肠炎(UC)的临床疗效和安全性。方法选取医院2021年1月至2023年6月收治的轻中度大肠湿热型UC患者57例,随机分为观察组(28例)和对照组(29例)。两组患者均口服美沙拉嗪,在此基础上,对照组患者加用美沙拉嗪直肠栓剂治疗,观察组患者加用双黄溃结宁保留灌肠。两组患者均连续治疗12周。结果两组患者的临床缓解率相当(92.9%比86.2%,P>0.05)。观察组患者的中医证候改善有效率及生活质量评分均显著优于对照组(P<0.05或P<0.01)。两组均未发生不良反应。结论双黄溃结宁灌肠方治疗轻中度大肠湿热型溃疡性结肠炎疗效较好,安全性较高。

Clinical Study on Treatment of Hyperuricaemia by Retention Enema of Chinese Herbal Medicine Combined with Allopurinol

Objective:To study the effect of retention enema of Chinese herbal medicine combined with allopurinol in treating hyperuricaemia(HUE).Methods:Seventy-eight patients with HUE were assigned to two groups,the 40 patients in the treated group were treated with retention enema of Chinese herbal medicine combined with oral intake of allopurinol,and the 38 patients in the control group were treated with allopurinol alone. The therapeutic course for all was 6 weeks.The clinical efficacy,changes of symptoms,blood le...

消水圣愈汤治疗老年肺源性心脏病临床观察

目的探讨消水圣愈汤对老年慢性肺源性心脏病(CPHD)患者血栓前状态指标及血清白细胞介素-8(IL-8)和肽素(Copeptin)水平的影响。方法将117例老年CPHD患者随机分为对照组(58例)和试验组(59例)。对照组予常规对症治疗,试验组在对照组的基础上予消水圣愈汤治疗,两组均治疗4周。比较两组临床疗效、血栓前状态指标及血清IL-8、Copeptin水平。结果治疗后,试验组总有效率为94.92%(56/59),高于对照组的79.31%(46/58)(P<0.05)。与对照组比较,试验组治疗后血浆黏度、血浆纤维蛋白原(FIB)水平、血清D-二聚体(D-D)、血管性假血友病因子(vWF)、内皮素(ET-1)水平较低,血清IL-8、Copeptin水平较低(P<0.05)。结论消水圣愈汤能明显改善老年CPHD患者血栓前状态,减轻炎症反应,促进心功能恢复,临床疗效显著。

自拟清化止痛汤联合中药灌肠治疗湿热瘀结型急性盆腔炎的临床效果观察

目的分析湿热瘀结型急性盆腔炎患者临床治疗过程中使用自拟清化止痛汤联合中药灌肠治疗的效果。方法选取60例急性盆腔炎(湿热瘀结型)患者,根据随机数字表法将患者分为两组,每组30例。对照组接受常规西药治疗,治疗组在对照组基础上接受自拟清化止痛汤联合中药灌肠治疗。对比两组治疗效果。结果相比对照组,治疗后治疗组症状缓解时间明显缩短(P<0.05),且主症评分和次症评分明显降低(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论自拟清化止痛汤联合中药灌肠治疗湿热瘀结型急性盆腔炎具有较好的效果和安全性。

中药灌肠对急性期溃疡性结肠炎的临床疗效及肠道黏膜修复作用的Meta分析

目的评价中药灌肠治疗急性期或活动期溃疡性结肠炎(UC)的有效性及对黏膜修复作用的疗效。方法检索中英文数据库,包括中国学术期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、中文科技期刊数据库(VIP)、万方数据库、临床试验注册登记库、PubMed、Embase等,时间为建库至2023年10月,筛选随机对照试验(RCTs),采用RevMan5.3软件对纳入的研究进行Meta分析。结果共纳入17篇RCTs,Meta分析结果示:总有效率[RR=1.22,95%CI=(1.15,1.28),P<0.01];腹泻积分[SMD=-1.38,95%CI=(-2.00,-0.77),P<0.01];脓血便积分[SMD=-1.09,95%CI=(-1.64,-0.53),P<0.01];Baron评分[SMD=-1.38,95%CI=(-2.05,-0.70),P<0.01];黏膜组织评分[SMD=-2.00,95%CI=(-3.35,-0.66),P<0.01];白细胞介素-6(IL-6)水平[SMD=-3.11,95%CI=(-5.71,-0.50),P=0.02];白细胞介素-10(IL-10)水平[SMD=1.65,95%CI=(1.35,1.95),P<0.01];肿瘤坏死因子-α(TNF-α)水平[SMD=-1.93,95%CI=(-2.48,-1.39),P<0.01]。结论中医药灌肠辅助治疗急性期或活动期UC有助于提高治疗效果,缓解腹泻及脓血便的临床症状,促进肠道黏膜修复,抑制炎性因子的释放。

中药灌肠联合多西环素、甲硝唑治疗合并慢性子宫内膜炎的不孕患者的临床研究

目的探讨中药灌肠联合多西环素、甲硝唑对合并慢性子宫内膜炎(CE)的不孕患者治疗效果及辅助生育结局影响。方法选取2021年6月至2022年5月广东省妇幼保健院收治的80例合并CE的不孕患者,采用随机数字表法将其分为治疗组和对照组,每组各40例。对照组采用多西环素、甲硝唑治疗,治疗组在此基础上加用中药灌肠治疗。比较两组患者治疗前后的疗效。结果两组患者的临床总有效率、子宫内膜形态疗效、妊娠结局、气虚乏力积分比较,差异无统计学意义(P>0.05)。治疗组治疗后的下腹坠痛积分、月经不调积分、白带异常积分、面色萎黄积分、脉沉细积分、血管阻力指数(RI)和血流搏动指数(PI)均低于对照组,差异有统计学意义(P<0.05)。另外,治疗组治疗后的内膜厚度、血流指数(FI)、子宫内膜病理组织疗效均高于对照组,差异有统计学意义(P<0.05)。结论CE合并不孕患者采取中药灌肠联合多西环素、甲硝唑治疗可有效提升临床疗效,改善中医证候,提高辅助生育成功率。

针刺结合中药保留灌肠对溃疡性结肠炎的疗效及免疫功能的影响

目的:探讨针刺结合中药保留灌肠治疗溃疡性结肠炎(UC)的临床疗效及其改善免疫功能的作用。方法:选取符合纳入标准的UC患者70例,依据随机数字表随机分为观察组和对照组,各35例。对照组给予美沙拉嗪缓释片,观察组在对照组基础上加用针刺与中药保留灌肠疗法,两组均治疗8周。比较两组患者治疗前后血清免疫功能指标CD3^(+)、CD4^(+)与CD8^(+)含量、炎症因子指标白细胞介素(IL)-1β、IL-23与转化生长因子-β1(TGF-β1)的改善情况。结果:治疗后,两组患者TGF-β1、CD3^(+)、CD4^(+)含量均较治疗前明显升高(P<0.05),IL-1β、IL-23、CD8^(+)含量下降(P<0.05);且观察组治疗后TGF-β1、CD3^(+)和CD4^(+)水平均高于对照组(P<0.05),IL-1β、IL-23、CD8^(+)水平均低于对照组(P<0.05)。结论:针刺结合中药保留灌肠治疗能显著改善UC患者免疫功能,降低其炎症因子水平。

清热愈疡汤治疗溃疡性结肠炎对患者肠道菌群紊乱和改善炎症效果的组方分析

目的探究清热愈疡汤治疗溃疡性结肠炎的效果,分析其组方对患者肠道菌群和炎症因子的影响。方法选取上海中医药大学附属曙光医院肛肠科2021年1月-2022年9月收治的溃疡性结肠炎患者100例,按随机数字表法将患者分成观察组与对照组,各50例。对照组采用常规治疗,观察组在常规治疗的基础上采用清热愈疡汤灌肠治疗。比较2组患者的临床疗效、治疗前后的肠道菌群、炎症因子[肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)、单核细胞趋化蛋白-1(monocyte chemotactic protein 1,MCP-1)、白细胞介素-10(interleukin 10,IL-10)]水平、中医证候积分、Baron内镜积分、梅奥(Mayo)评分以及不良反应的发生情况。结果观察组的治疗总有效率(92.00%)较对照组(82.00%)明显提高,差异具有统计学意义(P<0.05)。治疗后较治疗前,2组双歧杆菌水平上升,乳酸杆菌、肠杆菌、肠球菌水平均下降,且观察组较对照组的双歧杆菌水平上升明显,乳酸杆菌、肠杆菌、肠球菌水平下降明显,差异具有统计学意义(P<0.05)。治疗后较治疗前2组TNF-α、MCP-1水平均下降,IL-10水平上升,且观察组较对照组的TNF-α、MCP-1水平下降明显,IL-10水平上升明显,差异具有统计学意义(P<0.05)。治疗后较治疗前2组的中医证候积分、Baron内镜积分及Mayo评分均下降,且观察组较对照组的中医证候积分、Baron内镜积分及Mayo评分下降明显,差异具有统计学意义(P<0.05)。观察组的不良反应总发生率(2.00%)较对照组(14.00%)明显降低,差异具有统计学意义(P<0.05)。结论清热愈疡汤在溃疡性结肠炎中的治疗效果较好,能够调节患者肠道菌群紊乱,减轻炎症反应,且安全性较好,值得临床推广应用。

中药灌肠治疗溃疡性结肠炎指南共识质量评价与内容分析

目的评价中药灌肠治疗溃疡性结肠炎(ulcerative colitis,UC)临床实践指南(clinical practice guidelines,CPGs)和专家共识的质量,并对推荐的中药灌肠方案进行内容一致性分析。方法检索主要中英文数据库和医脉通、SIGN、NICE、WHO等指南网站及数据库,检索时限为建库至2023年11月1日。汇总分析中药灌肠相关推荐内容,并采用AGREE-China、RIGHT和JBI工具分别评价CPGs和专家共识的质量。结果最终纳入2部CPGs和5部专家共识。内容分析结果表明:各CPGs和专家共识中中药灌肠推荐意见存在不一致,未详细报告证据等级和推荐强度。结肠宁、锡类散和康复新液以及血竭、复方黄柏、青黛、乌梅和三七等是不同CPGs和共识中推荐频率相对较高的方剂和中药。AGREE-China 5个领域的总得分(报告率)分别为:(62.86±29.82)分、(76.07±23.29)分、(30.00±31.74)分、(85.24±17.53)分和(14.29±34.99)分。其中,4篇强推荐、2篇弱推荐和1篇不推荐。RIGHT评价结果显示:CPGs报告项目占45.71%、未报告占44.29%、部分报告(不适用)占10.00%。JBI评价结果显示:专家共识整体质量较高。结论我国中药灌肠治疗UC相关CPGs和共识整体方法学质量有待进一步加强,不同CPG和共识中药灌肠治疗UC相关推荐内容不全面且证据基础不足。期待后期国内研究者整合现有CPG和共识证据,制定全面规范的本土化中药灌肠治疗UC的循证指南,提高适用性,正确指导临床和护理合理选择灌肠中药,发挥中药灌肠疗护UC的特色优势。

国医大师王晞星内外合治放射性直肠炎经验撷菁

放射性直肠炎(RP)作为盆腔恶性肿瘤放射治疗后常见的并发症之一,其发病率逐年增加。由于西医治疗目前无特异性药物,且病情易反复、长期效果不佳等缺点,严重影响了肿瘤患者的生活质量。国医大师王晞星教授根据多年诊疗经验,认为应当内外合治RP,临床疗效显著。本文深入剖析王晞星教授3期诊治RP之病机及治法方药,介绍肠瑞灌肠剂等外治方法。并附验案1则加以佐证,以期为临床提供参考。

红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效研究

目的探讨红藤汤加减灌肠治疗粘连性肠梗阻的临床疗效。方法选取2022年9月至2023年4月该院收治的86例粘连性肠梗阻患者作为研究对象,采用随机数字表法分为试验组与对照组,每组43例。对照组给予常规西药治疗,试验组在对照组基础上加用红藤汤加减灌肠治疗。比较两组治疗前及治疗3、7 d后的中医证候积分,患者血液标本中性粒细胞/淋巴细胞(NLR),比较两组疗效及不良反应发生率,比较两组恢复时间(胃管留置时间、腹痛缓解时间、腹胀缓解时间、首次排气时间、自行排便时间、气液平面消失时间、住院时间)及研究周期内因肠梗阻总住院次数。结果试验组治疗总有效率(93.02%)明显高于对照组(76.74%),差异有统计学意义(χ^(2)=4.440,P=0.035)。重复测量方差分析结果显示,两组治疗前及治疗3、7 d后的中医证候积分存在组间效应、时间效应、组间与时间的交互效应(P<0.05)。试验组胃管留置时间、腹痛缓解时间、腹胀缓解时间、首次排气时间、自行排便时间、气液平面消失时间、住院时间均短于对照组(P<0.05);试验组研究周期内因肠梗阻总住院次数少于对照组(P<0.05)。重复测量方差分析结果显示,两组治疗前及治疗3、7 d后的NLR存在组间效应、时间效应、组间与时间的交互效应(P<0.05)。两组不良反应发生率比较,差异无统计学意义(χ2=0.387,P=0.534)。结论粘连性肠梗阻采用红藤汤加减灌肠治疗,能有效调节机体NLR,加快临床症状缓解,提高临床疗效。

中药灌肠液辅助治疗溃疡性结肠炎的作用机制研究

目的基于分子药理学方法研究一种中药灌肠制剂对小鼠溃疡性结肠炎的保护及辅助治疗作用。方法构建葡聚糖硫酸钠盐诱导的溃疡性结肠炎小鼠模型,随机分为正常对照组、模型对照组、美沙拉嗪组、美沙拉嗪+灌肠液组,除正常对照组外,其余各组小鼠每天自由饮用4%葡聚糖硫酸钠盐溶液7 d。美沙拉嗪+灌肠液组每天灌胃给予0.52 g·kg^(-1)美沙拉嗪,且每天早晚用自制中药制剂灌肠;美沙拉嗪组每天灌胃给予0.52 g·kg^(-1)美沙拉嗪,且每天早晚用0.9%氯化钠溶液灌肠;正常对照组和模型对照组每天用0.9%氯化钠溶液灌胃,且每天早晚用0.9%氯化钠溶液灌肠,连续14 d后,取结肠组织冷冻备用。结果溃疡性结肠炎可使小鼠体质量显著下降,美沙拉嗪可以帮助小鼠减少体质量下降趋势,美沙拉嗪+灌肠液组效果优于美沙拉嗪组。苏木精-伊红染色法染色及组织学评分结果显示,美沙拉嗪能有效降低小鼠结肠组织的组织学评分,合用灌肠液可以加强这一作用;采用酶联免疫吸附测定方法检测小鼠结肠组织中肿瘤坏死因子-α、干扰素-γ以及白细胞介素-6的含量,灌肠液能增强美沙拉嗪对炎性因子的下调作用;采用蛋白质免疫印迹试验法检测小鼠结肠组织中凋亡基因cleaved caspase-3,Bax,Bcl-2的表达情况,灌肠液可增强美沙拉嗪对cleaved caspase-3、Bax蛋白的上调作用和对Bcl-2蛋白的下调作用。结论联合应用中药灌肠液能增强美沙拉嗪对小鼠溃疡性结肠炎的治疗作用、对炎性因子和细胞凋亡的抑制作用,为临床联合应用提供理论依据。

中医药治疗急性胰腺炎研究进展

急性胰腺炎(AP)是最常见的急腹症之一,其发病特征以上腹部剧烈疼痛和消化道症状为主。AP病情复杂,且发病机制尚不明确,中医药治疗AP具有特色优势,中医药治疗AP以病因病机为基础,辨证分期结合,综合运用中医内外治法辨证施治。临床常用中药内治(中药单体、单味药、复方和中成药注射液)、中药灌肠、贴敷以及针刺等多种治疗方法,在缓解患者临床症状、减轻患者脏器损伤、提高机体免疫力等方面效果显著。综述近年来中医药治疗AP的应用现状,为相关研究提供参考。

清肾颗粒联合中药保留灌肠治疗非透析慢性肾脏病疗效观察

目的:观察清肾颗粒联合中药保留灌肠对非透析慢性肾脏病(CKD)3~5期患者的疗效,并探究其对患者营养状况及钙磷水平的影响。方法:采用清肾颗粒联合黄苓解毒泄浊颗粒保留灌肠治疗非透析CKD 3~5期患者,并设对照组和治疗组,观察临床疗效以及中医证候积分、营养状况改善情况(血清白蛋白、血红蛋白)、钙磷代谢情况(钙、磷等)指标。结果:治疗组和对照组的临床疗效分别为67.5%(27/40)和35%(14/40),治疗组疗效显然胜于对照组(P<0.05);且与对照组比较,治疗组的营养状态和钙磷代谢都有了显著的提高,具有显著的差异。(P<0.05)。结论:清肾颗粒结合中药保留灌肠能缓解非透析CKD 3~5期患者的临床症状,改善其营养状况和钙磷水平,提高临床疗效。

养阴清肺汤联合化疗治疗肺癌研究进展

近年来,肺癌已逐渐成为全球范围内病发率和病死率最高的恶性肿瘤之一。在西医治疗方法上,根据肺癌分期,多包括放疗、化疗、靶向治疗或和手术治疗等,中医治疗则需要根据其病因病机辨证论治、对症治疗,二者在临床上相辅相成,有利于更好地提高治疗效果,改善患者生活质量。文章围绕养阴清肺汤联合化疗在治疗肺癌时的优势展开,阐述养阴清肺汤在肺癌患者化疗时的应用。