A new comprehensive set of data（n = 178） is compiled by adding a data set（n = 72） collected by Arioglu et al.（2007） to the data set（n = 106） presented in Rezazadeh and Eslami（2017）. Then, the compiled data s...A new comprehensive set of data（n = 178） is compiled by adding a data set（n = 72） collected by Arioglu et al.（2007） to the data set（n = 106） presented in Rezazadeh and Eslami（2017）. Then, the compiled data set is evaluated regardless of the variation in lithology/strength. The proposed empirical equation in this study comprises a wider range of uniaxial compressive strength（UCS）（0.15 MPa 〈 σ_（rc） 〈156 MPa） and various rock types. Rock mass cuttability index（RMCI） is correlated with shaft resistance（r_s） to predict the shaft resistance of rock-socketed piles. The prediction capacity of the RMCI versus r_s equation is also found to be in a fair good agreement with the presented data in Rezazadeh and Eslami（2017）. Since the RMCI is a promising parameter in the prediction of shaft resistance, the researchers in the rock-socketed pile design area should consider this parameter in the further investigations.展开更多
Based on the fictitious soil pile model, the effect of sediment on the vertical dynamic impedance of rock-socketed pile with large diameter was theoretically studied by means of Laplace transform technique and impedan...Based on the fictitious soil pile model, the effect of sediment on the vertical dynamic impedance of rock-socketed pile with large diameter was theoretically studied by means of Laplace transform technique and impedance function transfer method. Firstly, the sediment under rock-socketed pile was assumed to be fictitious soil pile with the same sectional area. The Rayleigh-Love rode model was used to simulate the rock-socketed pile and the fictitious soil pile with the consideration of the lateral inertial effect of large-diameter pile. The layered surrounding soils and bedrock were modeled by the plane strain model. Then, by virtue of the initial conditions and boundary conditions of the soil pile system, the analytical solution of the vertical dynamic impedance at the head of rock-socketed pile was derived for the arbitrary excitation acting on the pile head. Lastly, based on the presented analytical solution, the effect of sediment properties, bedrock property and lateral inertial effect on the vertical dynamic impedance at rock-socketed pile head were investigated in detail. It is shown that the sediment properties have significant effect on the vertical dynamic impedance at the rock-socketed pile head. The ability of soil-pile system to resist dynamic vertical deformation is weakened with the increase of sediment thickness, but amplified with the increase of shear wave velocity of sediment. The ability of soil pile system to resist dynamic vertical deformation is amplified with the bedrock property improving, but the ability of soil-pile system to resist vertical vibration is weakened with the improvement of bedrock property.展开更多
Semi-deep foundations socketed in rocks are considered to be a viable option for the foundations in the presence of heavy load imposed by high-rise structures, due to the low settlement and high bearing capacity. In t...Semi-deep foundations socketed in rocks are considered to be a viable option for the foundations in the presence of heavy load imposed by high-rise structures, due to the low settlement and high bearing capacity. In the optimum design of semi-deep foundations, prediction of the shaft bearing capacity, rs, of foundations socketed in rocks is thus critically important. In this study, the unconfined compressive strength(UCS), qu, has been applied in order to investigate the shaft bearing capacity. For this, a database of 106 full-scale load tests is compiled with UCS values of surrounding rocks, in which 34 tests with rock quality designation(RQD), and 5 tests with rock mass rating(RMR). The bearing rocks for semi-deep foundations include limestone, mudstone, siltstone, shale, granite, tuff, granodiorite, claystone, sandstone, phyllite, schist, and greywacke. Using the database, the applicability and accuracy of the existing empirical methods are evaluated and new relations are derived between the shaft bearing capacity and UCS based on the types of rocks. Moreover, a general equation in case of unknown rock types is proposed and it is verified by another set of data. Since rock-socketed shafts are supported by rock mass(not intact rock), a reduction factor for the compressive strength is suggested and verified in which the effect of discontinuities is considered using the modified UCS, qu(modified), based upon RMR and RQD in order to take into account the effect of the rock mass properties.展开更多
Piles socketed in soft rock were traditionally regarded as end bearing piles, and the loads transferred from superstructure were assumed in design to be shouldered totally by the piles. This paper was designated to ...Piles socketed in soft rock were traditionally regarded as end bearing piles, and the loads transferred from superstructure were assumed in design to be shouldered totally by the piles. This paper was designated to deal with the interaction between the piles socketed in weak rock and surrounding soil through field measurement. The pile head reaction and ground pressure under piled raft foundation were monitored, respectively. The analysis of the data measured in situ shows the characteristics of the pile embedded in weak rock are similar to that of friction pile to some extent. The rock socketed pile, together with the surrounding soil, shoulders the weight of the superstructure. It is suggested that soil bearing should be considered in designing the soft rock socketed piles, which can make the design more economical.展开更多
Interpreting reservoir properties through log data and logging responses in complex strata is critical for efficient petroleum exploitation,particularly for metamorphic rocks.However,the unsatisfactory accuracy of suc...Interpreting reservoir properties through log data and logging responses in complex strata is critical for efficient petroleum exploitation,particularly for metamorphic rocks.However,the unsatisfactory accuracy of such interpretations in complex reservoirs has hindered their widespread application,resulting in severe inconvenience.In this study,we proposed a multi-mineral model based on the least-square method and an optimal principle to interpret the logging responses and petrophysical properties of complex hydrocarbon reservoirs.We began by selecting the main minerals based on a comprehensive analysis of log data,X-ray diffraction,petrographic thin sections and scanning electron microscopy(SEM)for three wells in the Bozhong 19-6 structural zone.In combination of the physical properties of these minerals with logging responses,we constructed the multi-mineral model,which can predict the log curves,petrophysical properties and mineral profile.The predicted and measured log data are evaluated using a weighted average error,which shows that the multi-mineral model has satisfactory prediction performance with errors below 11%in most intervals.Finally,we apply the model to a new well“x”in the Bozhong 19-6 structural zone,and the predicted logging responses match well with measured data with the weighted average error below 11.8%for most intervals.Moreover,the lithology is dominated by plagioclase,K-feldspar,and quartz as shown by the mineral profile,which correlates with the lithology of the Archean metamorphic rocks in this region.It is concluded that the multi-mineral model presented in this study provides reasonable methods for interpreting log data in complex metamorphic hydrocarbon reservoirs and could assist in efficient development in the future.展开更多
目的研究ROCK/SLUG信号通路在内皮素-1(endo-thelin-1,ET-1)促进人卵巢癌细胞上皮向间充质转分化(epi-thelial to mesenchymal transition,EMT)中的作用。方法 ET-1处理人卵巢癌细胞株SK-OV-3和CaOV3,或共用ROCK的活化突变体转染细胞或...目的研究ROCK/SLUG信号通路在内皮素-1(endo-thelin-1,ET-1)促进人卵巢癌细胞上皮向间充质转分化(epi-thelial to mesenchymal transition,EMT)中的作用。方法 ET-1处理人卵巢癌细胞株SK-OV-3和CaOV3,或共用ROCK的活化突变体转染细胞或加入ROCK的抑制剂Y27632,并转染含SLUG启动子的pGL3质粒与Renilla质粒。实验末用Boyden小室体外侵袭实验检测细胞侵袭能力,细胞免疫荧光染色观察细胞形态,报告基因检测试剂盒检测SLUG启动子活性,用实时定量PCR和Western bot方法检测EMT相关基因的表达。结果 ET-1诱导SK-OV-3和CaOV3发生与EMT相一致的形态和基因变化,促进其细胞侵袭力;ET-1与内皮素A受体(endothelin A receptor,ETAR)结合,促进转录因子SLUG的转录;ET-1促进ROCK及fibronectin的表达,同时转染ROCK的活化突变体,促进ET-1诱导的fibronectin表达以及细胞侵袭力的增加。相反,ROCK抑制剂Y27632抑制ET-1对fibronectin表达以及细胞侵袭力的促进作用;转染ROCK的活化突变体,上调SLUG基因转录启动子活性促进其转录,抑制E-cadherin的转录。相反,ROCK的抑制剂Y27632抑制SLUG基因启动子的活性。结论 ET-1通过活化ROCK/SLUG通路促进人卵巢癌细胞发生EMT。展开更多
In many situations rocks are subjected to biaxial loading and the failure process is controlled by the lateral confinement stresses. The importance of confinement stresses has been recognized in the literature by many...In many situations rocks are subjected to biaxial loading and the failure process is controlled by the lateral confinement stresses. The importance of confinement stresses has been recognized in the literature by many researchers, in particular, its influence on strength and on the angle of fracture, but still there is not a clear description for the influence of confining stress on the crack propagation mechanism of rocks. This paper presents a numerical pro- cedure for the analysis of crack propagation in rock-like ma- terials under compressive biaxial loads. Several numerical simulations of biaxial tests on the rock specimen have been carried out by a bonded particle model （BPM） and the influ- ence of confinement on the mechanism of crack propagation from a single flaw in rock specimens is studied. For this purpose, several biaxial compressive tests on rectangular spec- imens under different confinement stresses were modeled in （2 dimensional particle flow code） PFC2D. The results show that wing cracks initiate perpendicular to the flaw and trend toward the direction of major stress, however, when the lat- eral stresses increase, this initiation angle gets wider. Also it is concluded that in addition to the material type, the initiation direction of the secondary cracks depends on confine- ment stresses, too. Besides, it is understood that secondary cracks may be produced from both tensile and shear mechanisms.展开更多
Kerogen content and kerogen porosity play a significant role in elastic properties of organic-rich shales. We construct a rock physics model for organic-rich shales to quantify the effect of kerogen content and keroge...Kerogen content and kerogen porosity play a significant role in elastic properties of organic-rich shales. We construct a rock physics model for organic-rich shales to quantify the effect of kerogen content and kerogen porosity using the Kuster and Toks6z theory and the selfconsistent approximation method. Rock physics modeling results show that with the increase of kerogen content and kerogen-related porosity, the velocity and density of shales decrease, and the effect of kerogen porosity becomes more obvious only for higher kerogen content. We also find that the Poisson＇s ratio of the shale is not sensitive to kerogen porosity for the case of gas saturation. Finally, for the seismic reflection responses of an organic-rich shale layer, forward modeling results indicate the fifth type AVO re- sponses which correspond to a negative intercept and a positive gradient. The absolute values of intercept and gradient increase with kerogen content and kerogen porosity, and present predictable variations associated with velocities and density.展开更多
基金support of Yapi Merkezi Construction and Industry Inc.,Istanbul,Turkey
文摘A new comprehensive set of data（n = 178） is compiled by adding a data set（n = 72） collected by Arioglu et al.（2007） to the data set（n = 106） presented in Rezazadeh and Eslami（2017）. Then, the compiled data set is evaluated regardless of the variation in lithology/strength. The proposed empirical equation in this study comprises a wider range of uniaxial compressive strength（UCS）（0.15 MPa 〈 σ_（rc） 〈156 MPa） and various rock types. Rock mass cuttability index（RMCI） is correlated with shaft resistance（r_s） to predict the shaft resistance of rock-socketed piles. The prediction capacity of the RMCI versus r_s equation is also found to be in a fair good agreement with the presented data in Rezazadeh and Eslami（2017）. Since the RMCI is a promising parameter in the prediction of shaft resistance, the researchers in the rock-socketed pile design area should consider this parameter in the further investigations.
基金Projects(51109084/E09070151308234/E08061) supported by the National Natural Science Foundation of China+1 种基金Project(2013J05079) supported by the Natural Science Foundation of Fujian Province,ChinaProject(Z012002) supported by the Open Research Fund of State Key Laboratory of Geomechanics and Geotechnical Engineering(Institute of Rock and Soil Mechanics,Chinese Academy of Sciences),China
文摘Based on the fictitious soil pile model, the effect of sediment on the vertical dynamic impedance of rock-socketed pile with large diameter was theoretically studied by means of Laplace transform technique and impedance function transfer method. Firstly, the sediment under rock-socketed pile was assumed to be fictitious soil pile with the same sectional area. The Rayleigh-Love rode model was used to simulate the rock-socketed pile and the fictitious soil pile with the consideration of the lateral inertial effect of large-diameter pile. The layered surrounding soils and bedrock were modeled by the plane strain model. Then, by virtue of the initial conditions and boundary conditions of the soil pile system, the analytical solution of the vertical dynamic impedance at the head of rock-socketed pile was derived for the arbitrary excitation acting on the pile head. Lastly, based on the presented analytical solution, the effect of sediment properties, bedrock property and lateral inertial effect on the vertical dynamic impedance at rock-socketed pile head were investigated in detail. It is shown that the sediment properties have significant effect on the vertical dynamic impedance at the rock-socketed pile head. The ability of soil-pile system to resist dynamic vertical deformation is weakened with the increase of sediment thickness, but amplified with the increase of shear wave velocity of sediment. The ability of soil pile system to resist dynamic vertical deformation is amplified with the bedrock property improving, but the ability of soil-pile system to resist vertical vibration is weakened with the improvement of bedrock property.
文摘Semi-deep foundations socketed in rocks are considered to be a viable option for the foundations in the presence of heavy load imposed by high-rise structures, due to the low settlement and high bearing capacity. In the optimum design of semi-deep foundations, prediction of the shaft bearing capacity, rs, of foundations socketed in rocks is thus critically important. In this study, the unconfined compressive strength(UCS), qu, has been applied in order to investigate the shaft bearing capacity. For this, a database of 106 full-scale load tests is compiled with UCS values of surrounding rocks, in which 34 tests with rock quality designation(RQD), and 5 tests with rock mass rating(RMR). The bearing rocks for semi-deep foundations include limestone, mudstone, siltstone, shale, granite, tuff, granodiorite, claystone, sandstone, phyllite, schist, and greywacke. Using the database, the applicability and accuracy of the existing empirical methods are evaluated and new relations are derived between the shaft bearing capacity and UCS based on the types of rocks. Moreover, a general equation in case of unknown rock types is proposed and it is verified by another set of data. Since rock-socketed shafts are supported by rock mass(not intact rock), a reduction factor for the compressive strength is suggested and verified in which the effect of discontinuities is considered using the modified UCS, qu(modified), based upon RMR and RQD in order to take into account the effect of the rock mass properties.
文摘Piles socketed in soft rock were traditionally regarded as end bearing piles, and the loads transferred from superstructure were assumed in design to be shouldered totally by the piles. This paper was designated to deal with the interaction between the piles socketed in weak rock and surrounding soil through field measurement. The pile head reaction and ground pressure under piled raft foundation were monitored, respectively. The analysis of the data measured in situ shows the characteristics of the pile embedded in weak rock are similar to that of friction pile to some extent. The rock socketed pile, together with the surrounding soil, shoulders the weight of the superstructure. It is suggested that soil bearing should be considered in designing the soft rock socketed piles, which can make the design more economical.
基金funded by Science and Technology Major Project of China National Offshore Oil Corporation(CNOOC-KJ 135 ZDXM36 TJ 08TJ).
文摘Interpreting reservoir properties through log data and logging responses in complex strata is critical for efficient petroleum exploitation,particularly for metamorphic rocks.However,the unsatisfactory accuracy of such interpretations in complex reservoirs has hindered their widespread application,resulting in severe inconvenience.In this study,we proposed a multi-mineral model based on the least-square method and an optimal principle to interpret the logging responses and petrophysical properties of complex hydrocarbon reservoirs.We began by selecting the main minerals based on a comprehensive analysis of log data,X-ray diffraction,petrographic thin sections and scanning electron microscopy(SEM)for three wells in the Bozhong 19-6 structural zone.In combination of the physical properties of these minerals with logging responses,we constructed the multi-mineral model,which can predict the log curves,petrophysical properties and mineral profile.The predicted and measured log data are evaluated using a weighted average error,which shows that the multi-mineral model has satisfactory prediction performance with errors below 11%in most intervals.Finally,we apply the model to a new well“x”in the Bozhong 19-6 structural zone,and the predicted logging responses match well with measured data with the weighted average error below 11.8%for most intervals.Moreover,the lithology is dominated by plagioclase,K-feldspar,and quartz as shown by the mineral profile,which correlates with the lithology of the Archean metamorphic rocks in this region.It is concluded that the multi-mineral model presented in this study provides reasonable methods for interpreting log data in complex metamorphic hydrocarbon reservoirs and could assist in efficient development in the future.
文摘目的研究ROCK/SLUG信号通路在内皮素-1(endo-thelin-1,ET-1)促进人卵巢癌细胞上皮向间充质转分化(epi-thelial to mesenchymal transition,EMT)中的作用。方法 ET-1处理人卵巢癌细胞株SK-OV-3和CaOV3,或共用ROCK的活化突变体转染细胞或加入ROCK的抑制剂Y27632,并转染含SLUG启动子的pGL3质粒与Renilla质粒。实验末用Boyden小室体外侵袭实验检测细胞侵袭能力,细胞免疫荧光染色观察细胞形态,报告基因检测试剂盒检测SLUG启动子活性,用实时定量PCR和Western bot方法检测EMT相关基因的表达。结果 ET-1诱导SK-OV-3和CaOV3发生与EMT相一致的形态和基因变化,促进其细胞侵袭力;ET-1与内皮素A受体(endothelin A receptor,ETAR)结合,促进转录因子SLUG的转录;ET-1促进ROCK及fibronectin的表达,同时转染ROCK的活化突变体,促进ET-1诱导的fibronectin表达以及细胞侵袭力的增加。相反,ROCK抑制剂Y27632抑制ET-1对fibronectin表达以及细胞侵袭力的促进作用;转染ROCK的活化突变体,上调SLUG基因转录启动子活性促进其转录,抑制E-cadherin的转录。相反,ROCK的抑制剂Y27632抑制SLUG基因启动子的活性。结论 ET-1通过活化ROCK/SLUG通路促进人卵巢癌细胞发生EMT。
文摘In many situations rocks are subjected to biaxial loading and the failure process is controlled by the lateral confinement stresses. The importance of confinement stresses has been recognized in the literature by many researchers, in particular, its influence on strength and on the angle of fracture, but still there is not a clear description for the influence of confining stress on the crack propagation mechanism of rocks. This paper presents a numerical pro- cedure for the analysis of crack propagation in rock-like ma- terials under compressive biaxial loads. Several numerical simulations of biaxial tests on the rock specimen have been carried out by a bonded particle model （BPM） and the influ- ence of confinement on the mechanism of crack propagation from a single flaw in rock specimens is studied. For this purpose, several biaxial compressive tests on rectangular spec- imens under different confinement stresses were modeled in （2 dimensional particle flow code） PFC2D. The results show that wing cracks initiate perpendicular to the flaw and trend toward the direction of major stress, however, when the lat- eral stresses increase, this initiation angle gets wider. Also it is concluded that in addition to the material type, the initiation direction of the secondary cracks depends on confine- ment stresses, too. Besides, it is understood that secondary cracks may be produced from both tensile and shear mechanisms.
基金supported by the National Natural Science Foundation of China under Grants U1262208the National Natural Science Foundation of China under Grants 41404090
文摘Kerogen content and kerogen porosity play a significant role in elastic properties of organic-rich shales. We construct a rock physics model for organic-rich shales to quantify the effect of kerogen content and kerogen porosity using the Kuster and Toks6z theory and the selfconsistent approximation method. Rock physics modeling results show that with the increase of kerogen content and kerogen-related porosity, the velocity and density of shales decrease, and the effect of kerogen porosity becomes more obvious only for higher kerogen content. We also find that the Poisson＇s ratio of the shale is not sensitive to kerogen porosity for the case of gas saturation. Finally, for the seismic reflection responses of an organic-rich shale layer, forward modeling results indicate the fifth type AVO re- sponses which correspond to a negative intercept and a positive gradient. The absolute values of intercept and gradient increase with kerogen content and kerogen porosity, and present predictable variations associated with velocities and density.
