Surgical management in biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury

AIM: To discuss the surgical method and skill of biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury. METHODS: From November 2005 to December 2006, eight patients with biliary restricture after Roux-en-Y hepaticojejunostomy for bile duct injury were admitted to our hospital. Their clinical data were analyzed retrospectively. RESULTS: Bile duct injury was caused by cholecys- tectomy in the eight cases, including seven cases with laparoscopic cholecystectomy and one with mini- incision choleystectomy. According to the classification of Strasberg, type E1 injury was found in one patient, type E2 injury in three, type E3 injury in two and type E4 injury in two patients. Both of the type E4 injury patients also had a vascular lesion of the hepatic artery. Six patients received Roux-en-Y hepaticojejunostomy for the second time, and one of them who had type E4 injury with the right hepatic artery disruption received right hepatectomy afterward. One patient who had type E4 injury with the proper hepatic artery lesion underwent liver transplantation, and the remaining one with type E3 injury received external biliary drainage. All the patients recovered fairly well postoperatively. CONCLUSION: Roux-en-Y hepaticojejunostomy is still the main approach for such failed surgical cases with bile duct injury. Special attention should be paid to concomitant vascular injury in these cases. The optimal timing and meticulous and excellent skills are essential to the success in this surgery.

Robotic assisted Roux-en-Y hepaticojejunostomy in a post-cholecystectomy type E2 bile duct injury

Roux-en-Y hepaticojejunostomy anastomosis is the treatment of choice for common hepatic duct injury type E2.It has been performed laparoscopically with the advancement of laparoscopic skill.Recently,a telemanipulative robotic surgical system was introduced,providing laparoscopic instruments with wrist-arm technology and 3-dimensional visualization of theoperative field.We present a case of 36-year-old female patient who had undergone elective cholecystectomy2 mo ago for gall stones and had a common bile duct injury during surgery.As the stricture was old and complete it could not be tackled endoscopically.We did a laparoscopic assisted adhesiolysis followed by robotic Roux-en-Y hepaticojejunostomy.No intraoperative complications or technical problems were encountered.Postoperative period was uneventful and she was discharged on the 4th postoperative day.At followup,she is doing well without evidence of jaundice or cholangitis.This is the first reported case of robotic hepaticojejunostomy following common bile duct injury.The hybrid technique gives the patient benefit of laparoscopic adhesiolysis and robotic suturing.

Treatment of Complicated Hepatic Cystic Hydatidosis with Intrabiliary Rupture by Pericystectomy in Combination with Roux-en-Y Hepaticojejunostomy

This study retrospectively reviewed 9 cases of complicated hepatic cystic hydatidosis with intrabiliary rupture who were surgically treated with pericystectomy in combination with Roux-en-Y hepaticojejunostomy in our hospital from 2004 to 2010. The clinical features, results of laboratory tests, B-mode ultrasonography and CT, post-operative recovery, days of hospital stay after the operation and post-operative complications were statistically analyzed and the patients were followed up. The subjects in our series included 7 males and 2 females, whose average age was 50.78±7.58 years. Before operation, 9 patients suffered from pain of the right upper quadrant and jaundice, which, in 4 cases (44.45%), were accompanied with fever and chills. Preoperative B-mode ul-trosonography and CT showed that all the 9 patients had single hydatid cyst, with their diameter being 9.33±1.58 cm on average. The lesions involved segments Ⅴ, Ⅵ in 6 cases, and segment Ⅳ in 3 cases. By WHO classification, 7 cases were classified as CE3 and 2 cases as CE4. They all had choledochectasia. The subjects underwent the surgery uneventfully. Intraoperatively, 2–4 biliary fistula orifices were found, with the average of the orifice being (0.79±0.20) cm. After the operation, one patient developed incision infection, one had pulmonary infection and one suffered from reflux cholangitis. No anastomotic leaks or peri-operative deaths took place and follow-up revealed no recurrence and implantative metastasis. We are led to conclude that pericystectomy in combination with Roux-en-Y hepaticojejunostomy can achieve satisfactory results for the treatment of complicated hepatic cystic hydatidosis with intrabiliary rupture.

Application of multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of bile hilar duct lake in the operation of hilar cholangiocarcinoma

BACKGROUND Hilar cholangiocarcinoma is the most common malignant tumor of the extrahepatic bile duct.Until now,radical resection has been the most effective method for the long-term survival of patients with the disease.However,many problems have emerged in the field of hepatobiliary surgery for a long time,including complex surgical procedures,low resection rate,and postoperative complications.We have adopted the“multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of a bile duct lake”technique in the treatment of hilar cholangiocarcinoma since 2008,and obtained satisfactory short-and longterm results.AIM To examine the feasibility of the application of multiple Roux-en-Y hepaticojejunostomy reconstruction by formation of a bile duct lake in the operation of hilar cholangiocarcinoma METHODS A retrospective analysis was performed for the clinical data,surgical methods,and results of 76 patients with hilar cholangiocarcinoma who were treated with hilar bile duct lake-forming multiple Roux-en-Y hepaticojejunostomy reconstruction at Gansu Provincial Hospital.RESULTS In all 76 cases,the operation was successful and no operative death occurred.The mean(range)operation time was 215.4±53.5 min(124–678 min),and the amount of bleeding during the operation was 428.2±63.8 mL(240–2200 mL).The overall 1-year survival rate was 78.9%,and the 3-year survival rate was 32.8%.CONCLUSION The multiple Roux-en-Y hepaticojejunostomy reconstruction technique with formation of a bile duct lake is safe and effective for the surgical treatment of hilar cholangiocarcinoma.

腹腔镜根治性全胃切除术非离断式与传统Roux-en-Y吻合术治疗食管胃结合部腺癌的效果和安全性比较研究

目的比较分析腹腔镜根治性全胃切除术(TLRG)非离断式与传统Roux-en-Y吻合术治疗SiewertⅡ和Ⅲ型局部进展期食管胃结合部腺癌(AEG)的效果和安全性。方法回顾性分析2021-08—2024-01安阳市人民医院行TLRG的109例SiewertⅡ和Ⅲ型AEG患者的临床资料,其中行非离断式Roux-en-Y吻合消化道重建55例(观察组),行传统Roux-en-Y吻合消化道重建54例(对照组)。比较2组患者的手术相关指标,检测手术前后患者的血清红蛋白(Hb)、总蛋白(TP)、白蛋白(ALB)、前白蛋白(PA)、转铁蛋白(TRF)营养指标水平。统计术后并发症发生率。结果观察组患者的消化道重建时间、手术时间及术后排气时间、进流质时间、住院时间均短于对照组,术中出血量少于对照组,差异均有统计学意义(P<0.05)。术后3个月,观察组患者的血清Hb、TP、ALB、PA、TRF水平均高于对照组,差异有统计学意义(P<0.05)。2组患者的术后并发症总发生率的差异无统计学意义(P>0.05)。结论与传统Roux-en-Y吻合术比较,非离断式Roux-en-Y吻合术应用于TLRG,可优化手术相关指标,改善患者的营养状况,而且安全性不受影响。

Petersen's hernia with chylous ascites following laparoscopic total gastrectomy and Roux-en-Y anastomosis:A case report and review of literature

BACKGROUND Petersen’s hernia occurring through the epiploic foramen of the greater omentum,is an uncommon type of internal hernia.When it presents with complications such as chylous ascites,which is the lymphatic fluid accumulation in the abdominal cavity,it is particularly rare.Following laparoscopic total gastrectomy and Roux-en-Y anastomosis,the incidence of this condition is exceedingly low.CASE SUMMARY A 62-year-old male patient developed Petersen’s hernia following laparoscopic total gastrectomy(LTG)for gastric cancer,after Roux-en-Y anastomosis.Intestinal torsion and obstruction were experienced by the patient,along with a small amount of chylous ascites.Imaging studies and clinical assessment confirmed the diagnosis.Emergency surgery was performed promptly for the patient in the operating room.The twisted small intestine was reduced and the defect in Petersen’s space was repaired.The procedure was successful in the correction of the intestinal torsion and approximation of the hernia without the need for bowel resection.The patient’s condition significantly improved following the surgery.The ascites evolved from a milky white appearance to a pale yellow,with a substantial decrease in the triglyceride levels in the ascitic fluid,implying a favorable recovery trajectory.The patient was monitored closely and received appropriate care postoperatively,including nutritional support and fluid management.CONCLUSION This report illustrates the significance of recognizing Petersen’s hernia as a potential complication following gastrectomy for gastric cancer.It highlights the fundamental role of early surgical intervention in the effective management of such complications.The favorable outcome in this patient illustrates that prompt and appropriate surgical management can deter the necessity for more extensive procedures such as bowel resection.

Proximal small intestinal bypass outperforms Roux-en-Y and jejunoileal bypass in glucose regulation in streptozotocin induced diabetic rats

BACKGROUND The efficacy of various bariatric surgeries varies in reducing blood glucose levels.Given the distinct mechanisms and anatomical alterations associated with each procedure,it is crucial to compare their glycemic control outcomes.We hypothesize that proximal small intestinal bypass(PSIB)is superior in blood glucose reduction over Roux-en-Y gastric bypass(RYGB)and jejunoileal bypass(JIB).AIM To compare the effectiveness of PSIB,RYGB,and JIB in lowering blood glucose.METHODS Rats with streptozotocin-induced diabetes were randomly divided into PSIB,RYGB,JIB,and sham-operated groups.Body weight,food intake,fasting blood glucose level,oral glucose tolerance test,insulin tolerance test,liver enzymes,and blood lipids were measured.RESULTS Postoperatively,only the JIB group had a lower body weight compared to the sham group.The food intake of the rats in all three surgical groups was significantly less than that in the sham group.Fasting blood glucose was reduced in all surgical groups and was lower in the PSIB group than in the RYGB and JIB groups.Glucose tolerance and insulin sensitivity improved in all three surgical groups compared to the sham group,but the improvement appeared earliest in the PSIB group.At six weeks postsurgery,the PSIB group showed a reduction in alanine transaminase levels and maintained a normal lipid profile.CONCLUSION PSIB demonstrated excellent hypoglycemic effects in the early postoperative period,and had better efficacy than RYGB and JIB.

Common bile duct stump stones and recurrent acute pancreatitis after Roux-en-Y choledochojejunostomy in a child:A case report

BACKGROUND Pancreaticobiliary maljunction(PBM)is a rare congenital abnormality in pancreaticobiliary duct development.PBM is commonly found in children,and it often leads to acute pancreatitis and other diseases as a result of pancreaticobiliary reflux.Roux-en-Y choledochojejunostomy is a common surgical method for the treatment of PBM,but there are several associated complications that may occur after this operation.CASE SUMMARY The patient,a 12-year-old female,was hospitalized nearly 20 times in 2021 for recurrent acute pancreatitis.In 2022,she was diagnosed with PBM and underwent laparoscopic common bile duct resection and Roux-en-Y choledochojejunostomy in a tertiary hospital.In the first year after surgery,the patient had more than 10 recurrent acute pancreatitis episodes.After undergoing abdominal computed tomography and other examinations,she was diagnosed with“residual bile duct stones and recurrent acute pancreatitis”.On January 30,2024,the patient was admitted to our hospital due to recurrent upper abdominal pain and was cured through endoscopic retrograde cholangiopancreatography.CONCLUSION This article reports a case of a child with distal residual common bile duct stones and recurrent acute pancreatitis after Roux-en-Y choledochojejunostomy for PBM.The patient was cured through endoscopic retrograde cholangiopancreatography.

直线切割吻合器在儿童腹腔镜胆总管囊肿根治术Roux-en-Y吻合中的应用

目的探讨直线切割吻合器应用于儿童腹腔镜胆总管囊肿根治术Roux-en-Y吻合中的有效性、安全性及可行性。方法本研究为前瞻性研究,选取2020年1月至2023年1月湖南省儿童医院接受腹腔镜胆总管囊肿根治术Roux-en-Y吻合的34例患儿作为研究对象,按照随机数字表法进行分组,采用直线切割吻合器实施Roux-en-Y吻合术的患儿纳入观察组(n=17),采用传统缝合法实施Roux-en-Y吻合术的患儿纳入对照组(n=17)。记录两组患儿手术时长、术中出血量、术后肠道功能恢复时间、首次进食流质时间、拔除引流管时间、术后住院时间、总住院费用和术后并发症发生率。结果34例均顺利完成手术,无一例中转开放手术。观察组与对照组手术时长[(130.43±31.32)min比(141.51±30.39)min]、术中出血量[(55.45±20.73)mL比(58.62±22.13)mL]差异均无统计学意义(P>0.05);观察组与对照组患儿术后肠道功能恢复时间[(4.03±0.42)min比(4.91±1.13)min]、首次进食流质时间[(3.95±0.61)d比(4.88±1.09)d]、拔除引流管时间[(5.95±0.68)d比(6.65±1.28)d]、术后住院时间[(8.29±2.17)d比(10.33±2.18)d]均短于对照组,差异均有统计学意义(P<0.05);观察组与对照组患儿总住院费用[(34948.17±1019.57)元比(35151.91±1151.15)元]、并发症发生率(1/17比2/17)差异无统计学意义(P>0.05)。结论直线切割吻合器在儿童腹腔镜胆总管囊肿根治术Roux-en-Y吻合中与传统缝合吻合技术的有效性和安全性无明显差异,可促进患儿术后恢复,值得临床推广应用。

肠系膜上动脉压迫综合征腹腔镜十二指肠空肠Roux-en-Y型吻合术后吻合口出血13例临床分析

肠系膜上动脉压迫综合征(superior mesenteric artery syndrome,SMAS)是指腹主动脉与肠系膜上动脉夹角变小,十二指肠水平部肠管受肠系膜上动脉压迫出现急、慢性肠梗阻表现的临床综合征[1],临床表现为间歇性或持续性腹胀、腹痛、恶心、呕吐胆汁及宿食等一系列症候群[2]。SMAS可先给予营养支持、保守治疗,若效果不佳可进行手术治疗[3]。腹腔镜手术治疗SMAS已被证实安全、可行[4-5]。

腹腔镜Roux-en-Y胃旁路术后内疝肠梗阻的防治

随着腹腔镜Roux-en-Y胃旁路术的开展,手术例数逐渐增加,其并发症的防治至关重要。肠梗阻是腹腔镜Roux-en-Y胃旁路术的严重并发症之一,临床症状不典型,诊断假阴性率较高,容易发展为肠坏死,造成严重后果。因此预防、诊断、治疗腹腔镜Roux-en-Y胃旁路术后肠梗阻是减少围手术期死亡、肠坏死等严重并发症的关键。内疝是肠梗阻最常见的病因,预防、早期诊断、治疗内疝可预防大部分肠梗阻的发生。本文现总结国内外减重代谢外科医师的工作经验,对腹腔镜Roux-en-Y胃旁路术后内疝肠梗阻的发病情况、影响因素、诊断要点、治疗方法及预防措施作一综述。

CT定位穿刺经胆肠Roux-en-Y吻合输出袢通路治疗肝内胆管结石1例

胆肠Roux-en-Y吻合术后肝内胆管结石复发或胆肠吻合口狭窄比较常见,通常需要通过再次经腹手术来处理,亦有通过经皮经肝胆道镜取石术和留置皮下空肠盲袢,或经小肠ERCP等创伤小的胆道通路来解决。2023年12月我院收治1例肝内胆管结石患者,无合适经皮肝或空肠盲袢通路,通过CT定位下经皮穿刺建立胆肠Roux-en-Y吻合输出袢通路取出结石,诊疗经过顺利,无并发症发生,报告如下。

肝胆管盆式Roux-en-Y吻合术治疗复杂肝内胆管结石一例

左右叶肝内同时存在多发肝内胆管充满型成堆结石,或全肝5个或以上肝段内存在多发肝内胆管充满型成堆结石,而且不能通过肝段和(或)肝叶切除来除净的肝内胆管结石即称为复杂肝内胆管结石^([1-2])。目前临床上对复杂肝内胆管结石的治疗以肝切除术为主,少数甚至需要行肝移植术。有症状的肝内胆管结石既是患者的痛苦历程,亦往往是对外科医生的严峻挑战。70年代黄志强教授提出“解除梗阻、祛除病灶、取尽结石、通畅引流”的十六字原则。复杂肝内胆管结石治疗中采用盆式胆肠吻合术是指将已切开的1~3级肝管拼合、整形。

腹腔镜辅助Roux-en-Y吻合术与毕Ⅱ式吻合术用于远端胃癌根治术中消化道重建的疗效及安全性对比

目的比较远端胃癌根治术中应用腹腔镜辅助Roux-en-Y吻合术与毕Ⅱ式吻合术进行消化道重建的疗效和安全性,为临床提供参考。方法选取2020年2月至2023年3月常州市武进人民医院收治的50例胃癌患者为研究对象,按照随机数字表法分为对照组和观察组,各25例。对照组患者给予毕Ⅱ式吻合术治疗,观察组患者给予Roux-en-Y吻合术治疗。比较两组患者手术相关指标、营养指标、欧洲癌症研究与治疗组织生活质量量表(EORTC QLQ-C30)评分和并发症发生情况。结果与对照组比较,观察组患者的术中出血量更少,术后排气时间和住院时间均更短(均P<0.05);两组患者的手术时间、淋巴结清扫数和下床时间比较,差异均无统计学意义(均P>0.05)。术后6个月,两组患者血红蛋白(Hb)、白蛋白(ALB)和总蛋白(TP)水平均升高,BMI水平均降低,且观察组患者Hb、ALB和TP水平均更高(均P<0.05)。术后6个月,两组患者EORTC QLQ-C30评分均升高,且观察组更高(均P<0.05)。两组患者术后6个月并发症总发生率比较,差异无统计学意义(P>0.05)。观察组患者术后1年并发症总发生率低于对照组(P<0.05)。结论与毕Ⅱ式吻合术相比,远端胃癌根治术中应用腹腔镜辅助Roux-en-Y吻合术能更有效减少患者术中出血量,缩短患者术后排气时间和住院时间,还能有效改善营养状况与提高生活质量,且术后1年安全性良好。

腹腔镜袖状胃切除术与Roux-en-Y胃旁路术的临床应用现状

肥胖已成为全球最严重的公共卫生问题之一,其进展性、复发性、异质性、多因素性、易引发多种相关疾病等特点,使肥胖的治疗面临严峻挑战。减重手术被认为是目前治疗肥胖及其相关代谢性疾病最有效的方法。近年迅速发展的减重代谢外科带来多样的手术方式,其中腹腔镜袖状胃切除术与腹腔镜Roux-en-Y胃旁路术一直备受关注,是目前的主流术式,临床应用最广。本文现对两种术式的临床应用现状作一综述。

Roux-en-Y胃旁路术后边缘溃疡1例并文献复习

边缘溃疡是胃旁路术后典型的并发症,处理不当将导致穿孔、出血或狭窄等严重后果。中南大学湘雅三医院收治1例Roux-en-Y胃旁路术后并发吻合口边缘溃疡病人,该例病人因代谢综合征于2011年4月行腹腔镜下Roux-en-Y胃旁路术。2017年9月起反复出现腹痛、伴有大便性状改变。完善检查后诊断为边缘溃疡,考虑为胃囊扩大所致,遂于2019年10月行腹腔镜下扩张胃囊减容术+部分小肠切除术。术后病人规律行抑酸护胃治疗,但仍反复出现腹痛,伴有恶心呕吐,行胃镜提示吻合口边缘溃疡仍未愈合。遂于2022年6月完善术前准备后行腹腔镜下胃部分-胃肠吻合口-营养支空肠切除术+胃旁路修正手术。术后病人症状明显改善,8个月后随访胃镜下未见明显溃疡征象。此例病人历经2次修正手术,前后历时近5年,方得以治愈,显示此并发症处理难度大,过程繁琐。作者对胃旁路术后边缘溃疡这一并发症进行了相关文献复习,对此类并发症的危险因素、治疗及预防策略进行了总结,以期为减重代谢外科临床医师提供参考。

不同小肠旷置长度应用于Roux-en-Y胃旁路术的研究进展

小肠旷置是Roux-en-Y胃旁路术(Roux-en-Y gastric bypass,RYGB)的关键环节,然而小肠旷置的长度,依然没有统一意见。在实行精准医疗的当下,通过对病人的小肠长度进行精确测量,个体化的制定合适的小肠旷置长度,可以在达到更佳的手术效果的同时减少术后并发症的发生。此文将结合文献介绍RYGB中不同的小肠旷置长度对手术效果的影响,期望为未来的临床实践和研究设计提供新的思路。

单纯Roux-en-Y胃旁路术治疗超重或肥胖合并食管裂孔疝4例报告

目的:探讨腹腔镜Roux-en-Y胃旁路术对超重或肥胖合并食管裂孔疝患者的治疗效果。方法:回顾分析2012年11月至2019年12月为4例肥胖或超重合并食管裂孔疝患者行减重及代谢手术的临床资料及随访资料。结果:4例患者中2例超重合并2型糖尿病,2例肥胖合并糖尿病或糖耐量异常,均合并高血压及血脂异常。3例术前胃镜提示食管裂孔疝,其中2例合并反流性食管炎(洛杉矶分级B级),诊断为胃食管反流病。4例术中均探查明确食管裂孔疝。4例患者均行单纯Roux-en-Y胃旁路术,未对食管裂孔疝进行修补。术后随访2~11.5年。肥胖患者术后1年内体重下降明显,多余体重减少百分比分别为63.64%与70.59%。2例超重合并糖尿病患者分别于术后第6个月、5年时血糖升高,另1例肥胖伴糖尿病患者完全缓解。4例患者术后均未出现胃食管反流症状;1例轻度贫血;高血压均缓解,肝功、血脂未见异常。结论:单纯Roux-en-Y胃旁路术治疗肥胖合并食管裂孔疝患者可有效减轻体重,对于超重或肥胖伴随疾病有明显改善,是安全、有效的。

腹腔镜下胆管空肠Roux-en-Y吻合术治疗良性胆肠吻合口狭窄的疗效

目的:探究腹腔镜下胆管空肠Roux-en-Y吻合术治疗良性胆肠吻合口狭窄(BBEAS)的临床疗效。方法:选取2019年6月—2023年1月南阳市中心医院收治的100例胆肠吻合术后BBEAS患者作为研究对象,根据不同手术方法分为开放组和腹腔镜组,每组各50例。比较两组患者手术前后的实验室指标[总胆红素(TBIL)、直接胆红素(DBil)、丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、γ-谷胺酰转肽酶(γ-GT)、C-反应蛋白(CRP)]水平、术中和术后情况以及不良反应发生率。结果:治疗后,腹腔镜组患者CRP水平显著低于开放组患者,差异有统计学意义(t=3.802,P<0.05);腹腔镜组患者手术时间长于开放组患者,术中出血量少于开放组,术后排气时间、引流管拔除时间以及住院时间均短于开放组,差异有统计学意义(t=2.139、3.465、6.549、7.553、2.404,P<0.05);腹腔镜组患者术后不良反应发生率显著低于开放组患者,差异有统计学意义(χ^(2)=5.741,P<0.05)。结论:腹腔镜下行胆管空肠Roux-en-Y吻合术,能够有效降低BBEAS患者术后炎症反应,减少术中出血,缩短术后恢复时间,降低术后不良反应发生率。

Current approaches to the management of jejunal variceal bleeding at the site of hepaticojejunostomy after pancreaticoduodenectomy

Jejunal variceal bleeding at the site of hepaticojejunostomy after pancre-aticoduodenectomy due to portal hypertension caused by extrahepatic portal vein obstruction is a life-threatening complication and is very difficult to treat.Pharma-cotherapy,endoscopic methods,transcatheter embolization of veins supplying the jejunal afferent loop,portal venous stenting,and surgical procedures can be used for the treatment of jejunal variceal bleeding.Nevertheless,the optimal mana-gement strategy has not yet been established,which is due to the lack of ran-domized controlled trials involving a large cohort of patients necessary for their development.