We report the highly efficient conversion of readily available biomass-derived polyols with amines to valuable furfurylamines orβ-amino alcohols compounds using ruthenium catalysis.The reaction outcome is readily tun...We report the highly efficient conversion of readily available biomass-derived polyols with amines to valuable furfurylamines orβ-amino alcohols compounds using ruthenium catalysis.The reaction outcome is readily tuned by the simple addition of 4Åmolecular sieves(furfurylamines vs.β-amino alcohols)with high chemo-selectivity.The proposed reaction mechanism involves ruthenium-catalyzed hydrogen borrowing for the reduction of the imine intermediate and C–C bond cleavage of polyols via a retro-aldol process.A series of arylamines was suc-cessfully transformed into the desired products with moderate to good yields.展开更多
基金support from the National Natural Science Foundation of China(NSFC,Nos.21633013,22022204).
文摘We report the highly efficient conversion of readily available biomass-derived polyols with amines to valuable furfurylamines orβ-amino alcohols compounds using ruthenium catalysis.The reaction outcome is readily tuned by the simple addition of 4Åmolecular sieves(furfurylamines vs.β-amino alcohols)with high chemo-selectivity.The proposed reaction mechanism involves ruthenium-catalyzed hydrogen borrowing for the reduction of the imine intermediate and C–C bond cleavage of polyols via a retro-aldol process.A series of arylamines was suc-cessfully transformed into the desired products with moderate to good yields.
