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The Empirical Analysis on the Dynamic Effect of Rural-urban Migration on the Consumption Growth of Residents in China——Based on Varying Parameter State-space Model 被引量:1
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作者 邹小芳 《Agricultural Science & Technology》 CAS 2016年第2期471-475,共5页
The research constructed varying parameter state-space model and per- formed estimation on dynamic relationship between urban-rural migration and aggre- gate consumption expenditure on basis of dual economic structure... The research constructed varying parameter state-space model and per- formed estimation on dynamic relationship between urban-rural migration and aggre- gate consumption expenditure on basis of dual economic structure. The results showed that urban consumption growth made the most contribution to aggregate consumption growth, followed by urban-rural migration caused consumption. The role of rural consumption growth kept stable, but consumption caused by population growth was decreasing. Therefore, China consumption growth mainly relies on urban consumption expenditure and urban-rural migration. 展开更多
关键词 rural-urban migration Household consumption expenditure URBANIZATION State-space Model
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Rural-urban Migration, Rural Household Income and Local Geographical Contexts——A Case of Northwestern Guangxi, China 被引量:2
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作者 YANG Chunyue LU Qi XIE Lishuang 《Chinese Geographical Science》 SCIE CSCD 2008年第1期17-23,共7页
This paper aims to examine New Economics of Labor Migration (NELM) in the northwestern Guangxi, China and investigate the relationships among rural-urban migration, rural household income and local geographical contex... This paper aims to examine New Economics of Labor Migration (NELM) in the northwestern Guangxi, China and investigate the relationships among rural-urban migration, rural household income and local geographical contexts. Stratified sampling and typical case study were adopted and 236 questionnaires were collected from four vil- lages, Daxin, Lixin, Longhe and Yongchang. We analyzed the rural-urban migration rate, household income and local geographical factors, focusing on the ratio of remittance income to total household income. Data descriptions and sta- tistical methods, such as Pearson Chi-square test, Contingency coefficient, Eta, Pearson correlation coefficient, t-test, multiple comparisons (LSD test, Tamhane T2, Dunnett T3 and Dunnet C test) were used. The results are as follows. Rural households’ income is diversified in survey villages so the motivation of rural-urban migration in the study area can be partly explained by NELM. The migration rate of households (the percentage of households with migrants in survey households) in survey villages varies from 50% to 86%, while the proportion of remittance income to house- hold income is in the range of 30% to 80%. In the village of Yongchang, with the least average arable land area per household, the remittance income plays a vital role in household income (80%). And the statistical findings show that the proportion is significantly and negatively correlated with arable land area per household. The conclusion is that di- rect effect of migration, i.e., the contribution of remittance to household income, is negatively correlated with the con- tribution of resources to local income. 展开更多
关键词 rural-urban migration household income local geographical contexts northwestern Guangxi
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Rural-urban Migration,Rural Household Income and Sustainable Development in Rural Areas of China 被引量:2
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作者 Lu Qi Yang Chunyue Li Juan 《Chinese Journal of Population,Resources and Environment》 北大核心 2008年第2期70-73,共4页
The objective of this paper is to investigate the rela- tionships among rural-urban migration,rural household income and sustainable development in rural areas of China.The typical case study is done and 288 questionn... The objective of this paper is to investigate the rela- tionships among rural-urban migration,rural household income and sustainable development in rural areas of China.The typical case study is done and 288 questionnaires are collected from five villages in Hebei and Guangxi provinces,China.The migration and remittance status,household income and sustainable devel- opment of rural areas are analyzed on the basis of questionnaires. Rural-urban migration is becoming a part of routine life in rural areas.And remittance is an important component in rural house- hold income.Rural-urban migration increases the arable land area per labor,which releases the tight human-land relationship in villages.In total,the migration increases the rural household in- come and accelerates the sustainable development of rural areas. 展开更多
关键词 rural-urban migration rural household income sustainable development rural areas
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Economic Growth, Demographic Change and Rural-Urban Migration in China 被引量:7
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作者 ZHONG Fu-ning LI Qing +1 位作者 XIANG Jing ZHU Jing 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2013年第10期1884-1895,共12页
Is China able to maintain fast growth after three decades? This paper tries to answer this question by: 1) arguing that factors contributed to sustained long-run growth at supply side;2) focusing on contributions ... Is China able to maintain fast growth after three decades? This paper tries to answer this question by: 1) arguing that factors contributed to sustained long-run growth at supply side;2) focusing on contributions of demographic dividend especially that of rural-urban migration;and 3) analyzing rural demographic change with information collected through village-wide household survey.Policy alternatives to realize remaining potential demographic dividend are proposed based on the analysis of changing rural demographic structure. 展开更多
关键词 demographic dividend rural-urban migration economic growth China
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Impacts of Rural-urban Migration on Food Consumption
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作者 Longling LI 《Asian Agricultural Research》 2022年第12期7-12,共6页
Due to limitation of resource conditions,rural-urban migration leads to increased food consumption and aggravates the tight balance between food supply and demand.This issue has attracted increasing attention.This pap... Due to limitation of resource conditions,rural-urban migration leads to increased food consumption and aggravates the tight balance between food supply and demand.This issue has attracted increasing attention.This paper analyzed the food consumption level and structure of migrant workers,changes in food consumption before and after entering the city,the change range of food consumption and the main influencing factors.Data analysis indicated that there are large differences in the quantity and structure of food consumption of migrant workers in different industries and regions.Migrant workers whose food consumption increased after entering the city were more than those whose food consumption decreased.The increase in income and the management of food provided by work units are the main factors influencing the increase in food consumption. 展开更多
关键词 Food security Population migration Food consumption
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The roles of macrophage migration inhibitory factor in retinal diseases 被引量:1
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作者 Hongbing Zhang Xianjiao Zhang +3 位作者 Hongsong Li Bing Wang Pei Chen Jiamin Meng 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第2期309-315,共7页
Macrophage migration inhibitory factor(MIF),a multifunctional cytokine,is secreted by various cells and participates in inflammatory reactions,including innate and adaptive immunity.There are some evidences that MIF i... Macrophage migration inhibitory factor(MIF),a multifunctional cytokine,is secreted by various cells and participates in inflammatory reactions,including innate and adaptive immunity.There are some evidences that MIF is involved in many vitreoretinal diseases.For example,MIF can exacerbate many types of uveitis;measurements of MIF levels can be used to monitor the effectiveness of uveitis treatment.MIF also alleviates trauma-induced and glaucoma-induced optic nerve damage.Furthermore,MIF is critical for retinal/choroidal neovascularization,especially complex neovascularization.MIF exacerbates retinal degeneration;thus,anti-MIF therapy may help to mitigate retinal degeneration.MIF protects uveal melanoma from attacks by natural killer cells.The mechanism underlying the effects of MIF in these diseases has been demonstrated:it binds to cluster of differentiation 74,inhibits the c-Jun N-terminal kinase pathway,and triggers mitogen-activated protein kinases,extracellular signal-regulated kinase-1/2,and the phosphoinositide-3-kinase/Akt pathway.MIF also upregulates Toll-like receptor 4 and activates the nuclear factor kappa-B signaling pathway.This review focuses on the structure and function of MIF and its receptors,including the effects of MIF on uveal inflammation,retinal degeneration,optic neuropathy,retinal/choroidal neovascularization,and uveal melanoma. 展开更多
关键词 diabetic retinopathy GLAUCOMA macrophage migration inhibitory factor migration inhibitory factor receptor optic neuropathy retinal degeneration retinal neovascular uveal melanoma UVEITIS
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Runx2 regulates peripheral nerve regeneration to promote Schwann cell migration and re-myelination 被引量:1
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作者 Rong Hu Xinpeng Dun +1 位作者 Lolita Singh Matthew C.Banton 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第7期1575-1583,共9页
Runx2 is a major regulator of osteoblast differentiation and function;however,the role of Runx2 in peripheral nerve repair is unclea r.Here,we analyzed Runx2expression following injury and found that it was specifical... Runx2 is a major regulator of osteoblast differentiation and function;however,the role of Runx2 in peripheral nerve repair is unclea r.Here,we analyzed Runx2expression following injury and found that it was specifically up-regulated in Schwann cells.Furthermore,using Schwann cell-specific Runx2 knocko ut mice,we studied peripheral nerve development and regeneration and found that multiple steps in the regeneration process following sciatic nerve injury were Runx2-dependent.Changes observed in Runx2 knoc kout mice include increased prolife ration of Schwann cells,impaired Schwann cell migration and axonal regrowth,reduced re-myelination of axo ns,and a block in macrophage clearance in the late stage of regeneration.Taken together,our findings indicate that Runx2 is a key regulator of Schwann cell plasticity,and therefore peripheral nerve repair.Thus,our study shows that Runx2 plays a major role in Schwann cell migration,re-myelination,and peripheral nerve functional recovery following injury. 展开更多
关键词 macrophage clearance migration peripheral nerve injury regeneration re-myelination RUNX2 Schwann cells
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Extreme Meteorological Drought Events over China(1951-2022):Migration Patterns,Diversity of Temperature Extremes,and Decadal Variations 被引量:1
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作者 Zhenchen LIU Wen ZHOU Xin WANG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第12期2313-2336,共24页
Recently,extreme meteorological droughts have affected China,causing terrible socioeconomic impacts.Despite previous research on the spatiotemporal characteristics and mechanisms of drought,two crucial issues remain s... Recently,extreme meteorological droughts have affected China,causing terrible socioeconomic impacts.Despite previous research on the spatiotemporal characteristics and mechanisms of drought,two crucial issues remain seldom explored.First,an event-oriented drought chronology with detailed spatiotemporal evolutions is urgently required.Second,the complex migration patterns and diversity of synchronous temperature extremes need to be quantitatively investigated.Accordingly,the main achievements of our investigation are as follows.We produced an event-oriented set of extreme meteorological droughts over China through the application of a newly developed 3D DBSCAN-based detection method(deposited on https://doi.org/10.25452/figshare.plus.25512334),which was verified with a historical atlas and monographs on a case-by-case basis.In addition,distinctive migration patterns(i.e.,stationary/propagation types)are identified and ranked,considering the differences in latitudinal zones and coastal/inland locations.We also analyze the diversity of synchronous temperature extremes(e.g.,hotness and coldness).Notably,an increasing trend in hot droughts occurred over China since the late 1990s,predominantly appearing to the south of 30°N and north of 40°N.All drought events and synchronous temperature extremes are ranked using a comprehensive magnitude index,with the 2022 summer-autumn Yangtze River hot drought being the hottest.Furthermore,Liang-Kleeman information flow-based causality analysis emphasizes key areas where the PDO and AMO influenced decadal variations in coverages of droughts and temperature extremes.We believe that the achievements in this study may offer new insights into sequential mechanism exploration and prediction-related issues. 展开更多
关键词 3D DBSCAN event-oriented drought set migration pattern compound climate extremes
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Rural-urban Migration and Dynamics of Income Distribution in China:A Non-parametric Approach 被引量:10
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作者 Yong Liu, Wei Zou 《China & World Economy》 SCIE 2011年第6期37-55,共19页
Extending the income dynamics approach in Quah (2003), the present paper studies the enlarging income inequality in China over the past three decades from the viewpoint of rural-urban migration and economic transiti... Extending the income dynamics approach in Quah (2003), the present paper studies the enlarging income inequality in China over the past three decades from the viewpoint of rural-urban migration and economic transition. We establish non-parametric estimations of rural and urban income distribution functions in China, and aggregate a population- weighted, nationwide income distribution function taking into account rural-urban differences in technological progress and price indexes. We calculate 12 inequality indexes through non-parametric estimation to overcome the biases in existingparametric estimation and, therefore, provide more accurate measurement of income inequalitY. Policy implications have been drawn based on our research. 展开更多
关键词 economic transition income distribution migration non-parametric estimation
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Different Roles of Land in Rural-Urban Migration:Evidence from China's Household Survey 被引量:4
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作者 Xuelong Wang 《China & World Economy》 SCIE 2013年第1期107-126,共20页
This paper explores the influence of land holding on rural-urban migration using China's 2008 household survey data. It shows that the contradictoryfindings of existing published literature can be explained by introd... This paper explores the influence of land holding on rural-urban migration using China's 2008 household survey data. It shows that the contradictoryfindings of existing published literature can be explained by introducing a migration distance variable. The empirical studies show that land holding plays a different role in short-distance and long-distance migration. Land holding has a U-shaped curve association with the probability of short- distance migration and has an inverted-U-shaped association with the probability of long-distance migration. Therefore, the government needs to provide more job information and migration subsidies to farmers who have little land to overcome difficulties in the process of migration so as to reduce rural-urban inequality. 展开更多
关键词 capital constraint INEQUALITY land system migration opportunity cost
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Migration pattern of a population of Barn Swallows(Hirundo rustica)breeding in East Asian tropical region
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作者 Li Tian Yu Liu +3 位作者 Yang Wu Zimei Feng Dan Hu Zhengwang Zhang 《Avian Research》 SCIE CSCD 2024年第3期299-307,共9页
Birds exhibit a high degree of migratory diversity,which is influenced by various ecological factors and life history strategies.Conducting studies on tropical bird migration,of which research is scarce,and comparing ... Birds exhibit a high degree of migratory diversity,which is influenced by various ecological factors and life history strategies.Conducting studies on tropical bird migration,of which research is scarce,and comparing it with temperate birds can enhance our understanding of bird migration behaviour and its underlying mecha-nisms.In this study,we explored the migration behaviour of a breeding population of the Barn Swallow(Hirundo rustica)in Zhanjiang,southern China,a region located in the northern tropics,using light-level geolocators.From 2021 to 2023,we deployed geolocators on 92 breeding swallows and retrieved geolocators successfully from 23 individuals.These swallows all exhibited migratory behaviour,and wintering on various islands in Southeast Asia.They displayed sex differences in their wintering locations.All males concentrated in Borneo,while females primarily chose Borneo but also dispersed to the Philippines,South China Sea,and Vietnam for wintering.The studied swallow population adopted a seasonal migration pattern of“indirect in autumn,direct in spring”,bypassing the ecological barrier of the South China Sea in autumn and tending to directly cross it in spring migration.Moreover,the distance and duration of autumn migration was significantly longer than those of the spring migration.Compared to temperate Barn Swallows,the Barn Swallow population breeding in Zhanjiang adopts a pattern of“intra-tropical migration”and initiates autumn migration earlier.The formation of their migration pattern may be limited by ecological and physiological factors. 展开更多
关键词 ASIA Chain migration Light-level geolocators migration Northern tropics
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The Impact of Hula Project (1993-2018) on Nutrient Migrations
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作者 Moshe Gophen 《Open Journal of Ecology》 2024年第3期215-227,共13页
During the 1950s the Hula wetlands and old lake were drained and the land converted utilization to agriculture and ecotourism. As a result of the drainage, the Peat Soil was exposed to atmospheric oxygen. The geochemi... During the 1950s the Hula wetlands and old lake were drained and the land converted utilization to agriculture and ecotourism. As a result of the drainage, the Peat Soil was exposed to atmospheric oxygen. The geochemical environment was modified from reductive to oxidative and the Nitrogen in it was converted from Ammonium to Nitrate. Intensive migration of Nitrate from the Hula Valley induced a national concern of water quality deterioration in the lake which was dissipated when Nitrogen deficiency was developed in Lake Kinneret. Forty years after drainage the ecosystem structure was renovated (Hula Project, HP) aimed at agricultural management and nutrient migration reduction. The paper examines through evaluation of the ecological data record (1993-2018) the impact of hydrological changes, attributed to the HP implementation on nutrient dynamics within surface waters in the Hula Valley. It is suggested that soil moisture elevation by irrigation in summer reduced Phosphorus and enhanced Nitrate concentrations. 展开更多
关键词 Nitrogen PHOSPHORUS migration RUNOFF Peat Land HEADWATERS
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Migration of a Progestin Implant into a Pulmonary Artery: Observation of a Case at the Reference Health Center of Commune III of the District of Bamako in Mali
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作者 Hamady Sissoko Souma Kodio +20 位作者 Hamidou Albachar Cheickna Sylla Salif Diarra Sidy Moctar Diakité Mohamed Traoré Souleymane Traoré Ibrahim Fomba Ouncoumba Diarra Nana Bah Drissa Diarra Mahamoudou Coulibaly Bocary Sidi Koné Hawa Samaké Ahmadou Coulibaly Mamadou Traoré Seydou Z. Dao Sitapha Dembélé Samou Diarra Konimba Koné Alou Samaké Sanogo Siaka Amara 《Open Journal of Obstetrics and Gynecology》 2024年第9期1431-1436,共6页
It was a 36-year-old patient, 5th Pregnancy, 5th Delivery, 4 live children, and I deceased, had a consultation in the department for the removal of implants. Questioning revealed that she had had the implant three yea... It was a 36-year-old patient, 5th Pregnancy, 5th Delivery, 4 live children, and I deceased, had a consultation in the department for the removal of implants. Questioning revealed that she had had the implant three years ago without medical follow-up. It was in view of the difficulties in extracting the capsule that the chest X-ray and CT scan carried out concluded that the implant had migrated into a branch of the left pulmonary artery. Therapeutic abstention has been the attitude of cardiovascular surgeons. 展开更多
关键词 migration IMPLANT Pulmonary Artery BAMAKO
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GIPC1 promotes tumor growth and migration in gastric cancer via activating PDGFR/PI3K/AKT signaling
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作者 TINGTING LI WEI ZHONG +10 位作者 LIU YANG ZHIYU ZHAO LI WANG CONG LIU WANYUN LI HAIYAN LV SHENGYU WANG JIANGHUA YAN TING WU GANG SONG FANGHONG LUO 《Oncology Research》 SCIE 2024年第2期361-371,共11页
The high mortality rate associated with gastric cancer(GC)has resulted in an urgent need to identify novel therapeutic targets for GC.This study aimed to investigate whether GAIP interacting protein,C terminus 1(GIPC1... The high mortality rate associated with gastric cancer(GC)has resulted in an urgent need to identify novel therapeutic targets for GC.This study aimed to investigate whether GAIP interacting protein,C terminus 1(GIPC1)represents a therapeutic target and its regulating mechanism in GC.GIPC1 expression was elevated in GC tissues,liver metastasis tissues,and lymph node metastases.GIPC1 knockdown or GIPC1 blocking peptide blocked the platelet-derived growth factor receptor(PDGFR)/PI3K/AKT signaling pathway,and inhibited the proliferation and migration of GC cells.Conversely,GIPC1 overexpression markedly activated the PDGFR/PI3K/AKT signaling pathway,and promoted GC cell proliferation and migration.Furthermore,platelet-derived growth factor subunit BB(PDGF-BB)cytokines and the AKT inhibitor attenuated the effect of differential GIPC1 expression.Moreover,GIPC1 silencing decreased tumor growth and migration in BALB/c nude mice,while GIPC1 overexpression had contrasting effects.Taken together,our findings suggest that GIPC1 functions as an oncogene in GC and plays a central role in regulating cell proliferation and migration via the PDGFR/PI3K/AKT signaling pathway. 展开更多
关键词 GIPC1 PDGFR Gastric cancer Proliferation migration
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Phase-stable wide-bandgap perovskites enabled by suppressed ion migration
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作者 Zhiyu Gao Yu Zhu +20 位作者 Jingwei Zhu Cong Chen Zongjin Yi Yi Luo Yuliang Xu Kai Wu Tianshu Ma Fangfang Cao Zijun Chen Fang Yao Juncheng Wang Wenwu Wang Chuanxiao Xiao Hao Huang Hongxiang Li Qianqian Lin Pei Cheng Changlei Wang Xia Hao Guanggen Zeng Dewei Zhao 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第9期120-128,共9页
Wide-bandgap(>1.7 eV)perovskites suffer from severe light-induced phase segregation due to high bromine content,causing irreversible damage to devices stability.However,the strategies of suppressing photoinduced ph... Wide-bandgap(>1.7 eV)perovskites suffer from severe light-induced phase segregation due to high bromine content,causing irreversible damage to devices stability.However,the strategies of suppressing photoinduced phase segregation and related mechanisms have not been fully disclosed.Here,we report a new passivation agent 4-aminotetrahydrothiopyran hydrochloride(4-ATpHCl)with multifunctional groups for the interface treatment of a 1.77-eV wide-bandgap perovskite film.4-ATpH^(+)impeded halogen ion migration by anchoring on the perovskite surface,leading to the inhibition of phase segregation and thus the passivation of defects,which is ascribed to the interaction of 4-ATpH^(+)with perovskite and the formation of low-dimensional perovskites.Finally,the champion device achieved an efficiency of 19.32%with an open-circuit voltage(V_(OC))of 1.314 V and a fill factor of 83.32%.Moreover,4-ATpHCl modified device exhibited significant improved stability as compared with control one.The target device maintained 80%of its initial efficiency after 519 h of maximum power output(MPP)tracking under 1 sun illumination,however,the control device showed a rapid decrease in efficiency after 267 h.Finally,an efficiency of 27.38%of the champion 4-terminal all-perovskite tandem solar cell was achieved by mechanically stacking this wide-bandgap top subcell with a 1.25-eV low-bandgap perovskite bottom subcell. 展开更多
关键词 Wide-bandgap perovskite Phase segregation lon migration Interface post-treatment All-perovskite tandems
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The activation of adenosine monophosphate–activated protein kinase inhibits the migration of tongue squamous cell carcinoma cells by targeting Claudin-1 via epithelial–mesenchymal transition
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作者 Xin-Yue Zhou Qiu-Ming Liu +7 位作者 Zhuang Li Xia-Yang Liu Qi-Wei Zhao Yu Wang Feng-Hua Wu Gang Zhao Rui Sun Xiao-Hong Guo 《Animal Models and Experimental Medicine》 CAS CSCD 2024年第5期606-616,共11页
Background:The role of Claudin-1 in tongue squamous cell carcinoma(TSCC)metastasis needs further clarification,particularly its impact on cell migration.Herein,our study aims to investigate the role of Claudin-1 in TS... Background:The role of Claudin-1 in tongue squamous cell carcinoma(TSCC)metastasis needs further clarification,particularly its impact on cell migration.Herein,our study aims to investigate the role of Claudin-1 in TSCC cell migration and its underlying mechanisms.Methods:36 TSCC tissue samples underwent immunohistochemical staining for Claudin-1.Western blotting and immunofluorescence analyses were conducted to evaluate Claudin-1 expression and distribution in TSCC cells.Claudin-1 knockdown cell lines were established using short hairpin RNA transfection.Migration effects were assessed through wound healing assays.Furthermore,the expression of EMTassociated molecules was measured via western blotting.Results:Claudin-1 expression decreased as TSCC malignancy increased.Adenosine monophosphate–activated protein kinase(AMPK)activation led to increased Claudin-1 expression and membrane translocation,inhibiting TSCC cell migration and epithelial–mesenchymal transition(EMT).Conversely,Claudin-1 knockdown reversed these inhibitory effects on migration and EMT caused by AMPK activation.Conclusions:Our results indicated that AMPK activation suppresses TSCC cell migration by targeting Claudin-1 and EMT pathways. 展开更多
关键词 AMPK CLAUDIN-1 EMT migration tongue squamous cell carcinoma
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MAD2L2 overexpression attenuates the effects of TNF-α-induced migration and invasion capabilities in colorectal cancer cells
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作者 HAOTONG SUN HEYING WANG +5 位作者 YANJIE HAO XIN LI JUN LING HUAN WANG FEIMIAO WANG FANG XU 《BIOCELL》 SCIE 2024年第9期1311-1322,共12页
Background:Colorectal cancer is a major global health concern,exacerbated by tumor necrosis factor-alpha(TNF-α)and its role in inflammation,with the effects of Mitotic Arrest Deficient 2 Like 2(MAD2L2)in this context... Background:Colorectal cancer is a major global health concern,exacerbated by tumor necrosis factor-alpha(TNF-α)and its role in inflammation,with the effects of Mitotic Arrest Deficient 2 Like 2(MAD2L2)in this context still unclear.Methods:The colorectal carcinoma cell lines HCT116 and SW620 were exposed to TNF-αfor a period of 24 h to instigate an inflammatory response.Subsequent assessments were conducted to measure the expression of inflammatory cytokines,the activity within the p38 mitogen-activated protein kinase(p38 MAPK)and Phosphoinositide 3-Kinase/AKT Serine/Threonine Kinase pathway(PI3K/AKT)signaling cascades.Transcriptome sequencing and subsequent integrative analysis with the Cancer Genome Atlas(TCGA)program database revealed a significant downregulation of the key factor MAD2L2.Enhancement of MAD2L2 expression was facilitated via lentiviral vector-mediated transfection.The influence of this overexpression on TNF-α-prompted inflammation,intracellular signaling pathways,and the migratory and invasive behaviors of the colorectal cancer cells was then scrutinized.Results:TNF-αtreatment significantly increased the expression of Interleukin-1 beta(IL-1β)and Interleukin-6(IL-6),activated the MAPK p38 and PI3K/AKT signaling pathways,and enhanced cell migration and invasion.A decrease in MAD2L2 expression was observed following TNF-αtreatment.However,overexpression of MAD2L2 reversed the effects of TNF-α,reducing IL-1βand IL-6 levels,attenuating PI3K/AKT pathway activation,and inhibiting cell migration and invasion.Conclusions:Overexpression of MAD2L2 attenuates the pro-inflammatory effects of TNF-α,suggesting that MAD2L2 plays a protective role against TNF-α-induced migration and invasion of colorectal carcinoma cells.Therefore,MAD2L2 holds potential as a therapeutic target in the treatment of colorectal cancer. 展开更多
关键词 Colorectal cancer TNF-Α MAD2L2 migration INVASION
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Migration Networks Pattern of China’s Floating Population from the Perspective of Complex Network
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作者 LIU Wangbao CHEN Ranran 《Chinese Geographical Science》 SCIE CSCD 2024年第2期327-341,共15页
Since China’s reform and opening-up,the growing disparity between urban and rural areas and regions has led to massive migration.With China’s Rural Revitalization Strategy and the industrial transfer from the easter... Since China’s reform and opening-up,the growing disparity between urban and rural areas and regions has led to massive migration.With China’s Rural Revitalization Strategy and the industrial transfer from the eastern coastal areas to the inland,the migration direction and pattern of the floating population have undergone certain changes.Using the 2017 China Migrants Dynamic Survey(CMDS),excluding Hong Kong,Macao,and Taiwan regions of China,organized by China’s National Health Commission,the relationship matrix of the floating population is constructed according to the inflow place of the interviewees and their outflow place(the location of the registered residence)in the questionnaire survey.We then apply the complex network model to analyze the migration direction and network pattern of China’s floating population from the city scale.The migration network shows an obvious hierarchical agglomeration.The first-,second-,third-and fourth-tier distribution cities are municipalities directly under the central government,provincial capital cities,major cities in the central and western regions and ordinary cities in all provinces,respectively.The migration trend is from the central and western regions to the eastern coastal areas.The migration network has‘small world’characteristics,forming nine communities.It shows that most node cities in the same community are closely linked and geographically close,indicating that the migration network of floating population is still affected by geographical proximity.Narrowing the urban-rural and regional differences will promote the rational distribution this population.It is necessary to strengthen the reform of the registered residence system,so that the floating population can enjoy urban public services comparable to other populations,and allow migrants to live and work in peace. 展开更多
关键词 complex network floating population migration network spatial pattern community structure
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Application of Gaussian Beam Summation Migration in Reflected In-seam Wave Imaging
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作者 HAN Jianguang LÜQingtian +2 位作者 ZHANG Zhiheng YANG Shun WANG Shuo 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第1期276-284,共9页
The geological conditions for coal mining in China are complex,with various structural issues such as faults and collapsed columns seriously compromising the safety of coal mine production.In-seam wave exploration is ... The geological conditions for coal mining in China are complex,with various structural issues such as faults and collapsed columns seriously compromising the safety of coal mine production.In-seam wave exploration is an effective technique for acquiring detailed information on geological structures in coal seam working faces.However,the existing reflected in-seam wave imaging technique can no longer meet the exploration precision requirements,making it imperative to develop a new reflected in-seam wave imaging technique.This study applies the Gaussian beam summation(GBS)migration method to imaging coal seams'reflected in-seam wave data.Firstly,with regard to the characteristics of the reflected in-seam wave data,methods such as wavefield removal and enveloped superposition are employed for the corresponding wavefield separation,wave train compression and other processing of reflected in-seam waves.Thereafter,imaging is performed using the GBS migration technique.The feasibility and effectiveness of the proposed method for reflected in-seam wave imaging are validated by conducting GBS migration tests on 3D coal-seam fault models with different dip angles and throws.By applying the method to reflected in-seam wave data for an actual coal seam working face,accurate imaging of a fault structure is obtained,thereby validating its practicality. 展开更多
关键词 reflected in-seam wave Gaussian beam summation migration numerical tests fault
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LFM Radar Source Passive Localization Algorithm Based on Range Migration
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作者 Dandan Li Deyi Wang Hao Huan 《Journal of Beijing Institute of Technology》 EI CAS 2024年第2期130-140,共11页
Traditional single-satellite passive localization algorithms are influenced by frequency and angle measurement accuracies,resulting in error estimation of emitter position on the order of kilometers.Subsequently,a sin... Traditional single-satellite passive localization algorithms are influenced by frequency and angle measurement accuracies,resulting in error estimation of emitter position on the order of kilometers.Subsequently,a single-satellite localization algorithm based on passive synthetic aper-ture(PSA)was introduced,enabling high-precision positioning.However,its estimation of azimuth and range distance is considerably affected by the residual frequency offset(RFO)of uncoopera-tive system transceivers.Furthermore,it requires data containing a satellite flying over the radia-tion source for RFO search.After estimating the RFO,an accurate estimation of azimuth and range distance can be carried out,which is difficult to achieve in practical situations.An LFM radar source passive localization algorithm based on range migration is proposed to address the dif-ficulty in estimating frequency offset.The algorithm first provides a rough estimate of the pulse repetition time(PRT).It processes intercepted signals through range compression,range interpola-tion,and polynomial fitting to obtain range migration observations.Subsequently,it uses the changing information of range migration and an accurate PRT to formulate a system of nonlinear equations,obtaining the emitter position and a more accurate PRT through a two-step localization algorithm.Frequency offset only induces a fixed offset in range migration,which does not affect the changing information.This algorithm can also achieve high-precision localization in squint scenar-ios.Finally,the effectiveness of this algorithm is verified through simulations. 展开更多
关键词 passive localization range migration residual frequency offset
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