This article introduces the basic structure of a symmetric self-electrooptic effect device （S-SEED）, and applies the Kirchoff＇ s current law and a purely equivalent capacitive model, to analyze S-SEED＇s switch cha...This article introduces the basic structure of a symmetric self-electrooptic effect device （S-SEED）, and applies the Kirchoff＇ s current law and a purely equivalent capacitive model, to analyze S-SEED＇s switch characteristics. Linear approximation and N-segment approximation are utilized to obtain S-SEED＇s voltage-time （V-T） and characteristics. Theoretical analysis is verified by simulations, and the results demonstrate that the precision of S-SEED＇s switch time can satisfy the requirement in applications with linear approximation. Moreover, the simulations compare S-SEED＇s switch characteristics with different input powers and input contrast ratios, which reveal that increasing input contrast ratio is an effective way to improve S-SEED＇s switch characteristics.展开更多
目的观察耳穴埋豆联合柴术汤治疗2型糖尿病(Type 2 diabetes mellitus,T2DM)伴抑郁患者的临床疗效及对神经内分泌指标的影响。方法选取2019年9月—2020年5月期间石家庄市中医院收治的90例T2DM伴抑郁患者,按简单随机化法分为治疗组、对照...目的观察耳穴埋豆联合柴术汤治疗2型糖尿病(Type 2 diabetes mellitus,T2DM)伴抑郁患者的临床疗效及对神经内分泌指标的影响。方法选取2019年9月—2020年5月期间石家庄市中医院收治的90例T2DM伴抑郁患者,按简单随机化法分为治疗组、对照1组和对照2组,各30例。治疗组采取氟哌噻吨美利曲辛片联合柴术汤、耳穴埋豆,对照1组采取氟哌噻吨美利曲辛片联合柴术汤,对照2组采取氟哌噻吨美利曲辛片。治疗3个月后,比较3组患者治疗效果、中医证候积分(心情抑郁、胸肋胀满、心烦易怒)、汉密尔顿抑郁量表24项(Hamilton depresssion scale-24,HAMD-24)、血糖指标[糖化血红蛋白(Gglycosylated hemoglobin,HbA1c)、空腹血糖(Fasting plasma glucose,FPG)、餐后2 h血糖(2 h blood glucose after meal,2 h PG)]、神经内分泌指标[5-羟色氨酸(5-hydroxytryptamine,5-HT)、多巴胺(Dopamine,DA)、促肾上腺皮质激素(Adrenocorticotrophic hormone,ACTH)]及不良反应情况。结果治疗3个月后,治疗组总有效率93.10%(27/29)高于对照2组55.17%(16/29)、对照1组65.52%(19/29),差异有统计学意义(P<0.05);对照2组和对照1组治疗总有效率比较,差异无统计学意义(P>0.05)。治疗3个月后3组患者中医证候积分及HAMD-24评分均低于治疗前,差异有统计学意义(P<0.05);且治疗组HAMD-24及心情抑郁、心烦易怒、胸肋胀满评分均低于对照2组、对照1组,对照1组低于对照2组,差异有统计学意义(P<0.05)。治疗3个月后3组患者FPG、2 h PG、HbA1c水平均低于治疗前,差异有统计学意义(P<0.05);且治疗组FPG、2 h PG、HbA1c水平均低于对照2组、对照1组,对照1组低于对照2组,差异有统计学意义(P<0.05)。治疗3个月后3组患者5-HT、DA水平均高于治疗前,ACTH水平均低于治疗前,差异有统计学意义(P<0.05);且治疗组5-HT、DA水平均高于对照2组、对照1组,ACTH水平均低于对照2组、对照1组,对照1组5-HT、DA水平均高于对照2组,ACTH水平低于对照2组,差异有统计学意义(P<0.05)。3组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论耳穴埋豆联合柴术汤有利于控制T2DM伴抑郁患者血糖和抑郁,提高治疗效果,且安全性高,机制可能与调节神经内分泌有关。展开更多
基金the National Natural Science Foundation of China (60677004)the Key Project of Chinese Ministry of Education (107011)the Key Laboratory of Broadband Optical Fiber Transmission and Communication Networks (UESTC), the Ministry of Education, and the Project Sponsored by the Teaching and Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
文摘This article introduces the basic structure of a symmetric self-electrooptic effect device （S-SEED）, and applies the Kirchoff＇ s current law and a purely equivalent capacitive model, to analyze S-SEED＇s switch characteristics. Linear approximation and N-segment approximation are utilized to obtain S-SEED＇s voltage-time （V-T） and characteristics. Theoretical analysis is verified by simulations, and the results demonstrate that the precision of S-SEED＇s switch time can satisfy the requirement in applications with linear approximation. Moreover, the simulations compare S-SEED＇s switch characteristics with different input powers and input contrast ratios, which reveal that increasing input contrast ratio is an effective way to improve S-SEED＇s switch characteristics.
文摘目的观察耳穴埋豆联合柴术汤治疗2型糖尿病(Type 2 diabetes mellitus,T2DM)伴抑郁患者的临床疗效及对神经内分泌指标的影响。方法选取2019年9月—2020年5月期间石家庄市中医院收治的90例T2DM伴抑郁患者,按简单随机化法分为治疗组、对照1组和对照2组,各30例。治疗组采取氟哌噻吨美利曲辛片联合柴术汤、耳穴埋豆,对照1组采取氟哌噻吨美利曲辛片联合柴术汤,对照2组采取氟哌噻吨美利曲辛片。治疗3个月后,比较3组患者治疗效果、中医证候积分(心情抑郁、胸肋胀满、心烦易怒)、汉密尔顿抑郁量表24项(Hamilton depresssion scale-24,HAMD-24)、血糖指标[糖化血红蛋白(Gglycosylated hemoglobin,HbA1c)、空腹血糖(Fasting plasma glucose,FPG)、餐后2 h血糖(2 h blood glucose after meal,2 h PG)]、神经内分泌指标[5-羟色氨酸(5-hydroxytryptamine,5-HT)、多巴胺(Dopamine,DA)、促肾上腺皮质激素(Adrenocorticotrophic hormone,ACTH)]及不良反应情况。结果治疗3个月后,治疗组总有效率93.10%(27/29)高于对照2组55.17%(16/29)、对照1组65.52%(19/29),差异有统计学意义(P<0.05);对照2组和对照1组治疗总有效率比较,差异无统计学意义(P>0.05)。治疗3个月后3组患者中医证候积分及HAMD-24评分均低于治疗前,差异有统计学意义(P<0.05);且治疗组HAMD-24及心情抑郁、心烦易怒、胸肋胀满评分均低于对照2组、对照1组,对照1组低于对照2组,差异有统计学意义(P<0.05)。治疗3个月后3组患者FPG、2 h PG、HbA1c水平均低于治疗前,差异有统计学意义(P<0.05);且治疗组FPG、2 h PG、HbA1c水平均低于对照2组、对照1组,对照1组低于对照2组,差异有统计学意义(P<0.05)。治疗3个月后3组患者5-HT、DA水平均高于治疗前,ACTH水平均低于治疗前,差异有统计学意义(P<0.05);且治疗组5-HT、DA水平均高于对照2组、对照1组,ACTH水平均低于对照2组、对照1组,对照1组5-HT、DA水平均高于对照2组,ACTH水平低于对照2组,差异有统计学意义(P<0.05)。3组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论耳穴埋豆联合柴术汤有利于控制T2DM伴抑郁患者血糖和抑郁,提高治疗效果,且安全性高,机制可能与调节神经内分泌有关。
