We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and...We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.展开更多
目的分析高血压患者生命质量(quality of life,QOL)的影响因素。方法应用SF-36量表(中文版)调查213例原发性高血压患者的QOL情况,以单因素方差分析、多元逐步线性回归对12种因素进行分析,寻找主要影响因素。结果年龄、居住地区、婚姻状...目的分析高血压患者生命质量(quality of life,QOL)的影响因素。方法应用SF-36量表(中文版)调查213例原发性高血压患者的QOL情况,以单因素方差分析、多元逐步线性回归对12种因素进行分析,寻找主要影响因素。结果年龄、居住地区、婚姻状况、在岗情况、血压控制情况、心功能、心血管系统合并症及家庭人均月收入对患者QOL总得分有显著影响。多元逐步线性回归分析显示,年龄、血压控制情况、心功能、心血管系统合并症及家庭人均月收入是主要影响因素,偏回归系数分别为-4.266、86.237、-48.048、-45.071和36.011。结论关注老龄及低收入高血压患者,积极控制血压、改善心功能、治疗心血管系统合并症对提高患者QOL有重要意义。展开更多
目的建立疾病生命质量谱，反映不同疾病人群的生命质量状态。方法采用健康调查简表（the MOS item short from health survey，SF-36）研究疾病人群生命质量的文献，对不同疾病人群生命质量的相对位置进行研究，采用系统聚类方法建立疾...目的建立疾病生命质量谱，反映不同疾病人群的生命质量状态。方法采用健康调查简表（the MOS item short from health survey，SF-36）研究疾病人群生命质量的文献，对不同疾病人群生命质量的相对位置进行研究，采用系统聚类方法建立疾病生命质量谱，以1～4级生命质量谱段代表严重疾病-较重疾病-中度疾病-轻度疾病的生命质量。结果生命质量的4级谱段反映了生命质量的不同水平：1级生命质量谱段的疾病主要造成躯体活动受限，总体生命质量很差；2级生命质量谱段为精神系统疾病，以心理健康受到严重影响为特点；3级生命质量谱段以慢性迁延性疾病为主，生命质量一般；4级生命质量谱段以轻度疾病或早期疾病为主，生命质量受疾病影响开始下降，但程度不重。结论疾病生命质量谱从轻度疾病到严重疾病的生命质量变化，为不同疾病人群的生命质量评价及疗效评价提供了简便直观的参照体系，同时也可以作为非疾病人群生命质量评价的参考体系，为描述不同群体的生命质量水平提供了新的表达方式。展开更多
文摘We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.
文摘目的分析高血压患者生命质量(quality of life,QOL)的影响因素。方法应用SF-36量表(中文版)调查213例原发性高血压患者的QOL情况,以单因素方差分析、多元逐步线性回归对12种因素进行分析,寻找主要影响因素。结果年龄、居住地区、婚姻状况、在岗情况、血压控制情况、心功能、心血管系统合并症及家庭人均月收入对患者QOL总得分有显著影响。多元逐步线性回归分析显示,年龄、血压控制情况、心功能、心血管系统合并症及家庭人均月收入是主要影响因素,偏回归系数分别为-4.266、86.237、-48.048、-45.071和36.011。结论关注老龄及低收入高血压患者,积极控制血压、改善心功能、治疗心血管系统合并症对提高患者QOL有重要意义。
文摘目的建立疾病生命质量谱，反映不同疾病人群的生命质量状态。方法采用健康调查简表（the MOS item short from health survey，SF-36）研究疾病人群生命质量的文献，对不同疾病人群生命质量的相对位置进行研究，采用系统聚类方法建立疾病生命质量谱，以1～4级生命质量谱段代表严重疾病-较重疾病-中度疾病-轻度疾病的生命质量。结果生命质量的4级谱段反映了生命质量的不同水平：1级生命质量谱段的疾病主要造成躯体活动受限，总体生命质量很差；2级生命质量谱段为精神系统疾病，以心理健康受到严重影响为特点；3级生命质量谱段以慢性迁延性疾病为主，生命质量一般；4级生命质量谱段以轻度疾病或早期疾病为主，生命质量受疾病影响开始下降，但程度不重。结论疾病生命质量谱从轻度疾病到严重疾病的生命质量变化，为不同疾病人群的生命质量评价及疗效评价提供了简便直观的参照体系，同时也可以作为非疾病人群生命质量评价的参考体系，为描述不同群体的生命质量水平提供了新的表达方式。
