目的 比较健康调查简表(the MOS item short from health survey,SF-36)和欧洲癌症研究和治疗组织肿瘤肺癌患者生存质量量表(the European Organization for Research and Treatment of Cancer Quality of Life Core 30 Questionnaire,E...目的 比较健康调查简表(the MOS item short from health survey,SF-36)和欧洲癌症研究和治疗组织肿瘤肺癌患者生存质量量表(the European Organization for Research and Treatment of Cancer Quality of Life Core 30 Questionnaire,EORTC QLQ-LC43)在肺癌患者生活质量测定中的应用效果。方法 选取2020年9月—2022年6月158例肺癌患者作为研究对象,分别采用SF-36量表和EORTC QLQ-LC43量表调查受试对象的生活质量,采用Pearson线性相关性分析比较两种量表不同维度评分之间的相关性,以Karnofsky评分(KPS评分)功能状态评分作为效标,比较两种生存质量量表的相关性及效度。结果 SF-36量表总克朗巴赫系数为0.766,分量表克朗巴赫系数为0.493~0.849。SF-36量表的躯体功能、躯体角色、躯体疼痛、情感职能、社会活动、一般健康等6个分量表分别与EORTC QLQ-LC43量表的躯体功能、角色功能、疼痛、情绪功能、社会功能、整体生活质量的6个分量表对应,其相关系数为0.784~0.842,相关性差异有统计学意义(P<0.001)。上述对应的分量表具有中等程度的一致性(Kappa值> 0.4)。不同临床分期分组中,肺癌患者SF-36各个维度得分与肿瘤分期显著相关,肿瘤分期越晚,生存质量得分越低(P<0.001)。肺癌患者SF-36各个维度得分与患者的体力状态得分显著相关,体力状态越差,生存质量得分越低(P <0.001)。结论 与EORTC QLQ-LC43量表相比,SF-36量表在评价肺癌患者生活质量方面具有较高的一致性和区分能力,可以作为EORTC QLQ-LC43量表的替代。展开更多
We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and...We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.展开更多
文摘目的 比较健康调查简表(the MOS item short from health survey,SF-36)和欧洲癌症研究和治疗组织肿瘤肺癌患者生存质量量表(the European Organization for Research and Treatment of Cancer Quality of Life Core 30 Questionnaire,EORTC QLQ-LC43)在肺癌患者生活质量测定中的应用效果。方法 选取2020年9月—2022年6月158例肺癌患者作为研究对象,分别采用SF-36量表和EORTC QLQ-LC43量表调查受试对象的生活质量,采用Pearson线性相关性分析比较两种量表不同维度评分之间的相关性,以Karnofsky评分(KPS评分)功能状态评分作为效标,比较两种生存质量量表的相关性及效度。结果 SF-36量表总克朗巴赫系数为0.766,分量表克朗巴赫系数为0.493~0.849。SF-36量表的躯体功能、躯体角色、躯体疼痛、情感职能、社会活动、一般健康等6个分量表分别与EORTC QLQ-LC43量表的躯体功能、角色功能、疼痛、情绪功能、社会功能、整体生活质量的6个分量表对应,其相关系数为0.784~0.842,相关性差异有统计学意义(P<0.001)。上述对应的分量表具有中等程度的一致性(Kappa值> 0.4)。不同临床分期分组中,肺癌患者SF-36各个维度得分与肿瘤分期显著相关,肿瘤分期越晚,生存质量得分越低(P<0.001)。肺癌患者SF-36各个维度得分与患者的体力状态得分显著相关,体力状态越差,生存质量得分越低(P <0.001)。结论 与EORTC QLQ-LC43量表相比,SF-36量表在评价肺癌患者生活质量方面具有较高的一致性和区分能力,可以作为EORTC QLQ-LC43量表的替代。
文摘We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.
