Using quadrupole mass spectrometer,calibration gas PFTBA was turned on in constant flow to get the signal intensity,and off to get the noise value.Different scan time and dwell time was used separately for full scan m...Using quadrupole mass spectrometer,calibration gas PFTBA was turned on in constant flow to get the signal intensity,and off to get the noise value.Different scan time and dwell time was used separately for full scan mode and SIM to find out the effect of scan rate on signal intensity and noise.展开更多
To find out the effect of scan rate on sensitivity in quadrupole mass spectrometer,DDV and 11 common hypnotic drugs were chosen for GC-MS analysis.Different scan time and dwell time was used separately for full scan m...To find out the effect of scan rate on sensitivity in quadrupole mass spectrometer,DDV and 11 common hypnotic drugs were chosen for GC-MS analysis.Different scan time and dwell time was used separately for full scan mode and SIM.Then charasteristic ions were extracted to calculate signal to noise values.展开更多
The comprehensive scan technique using single quadruple GC-MS was introduced and demonstrated in different applications for improving the sensitivity,selectivity,and speed of analysis of multi-compound in complex matr...The comprehensive scan technique using single quadruple GC-MS was introduced and demonstrated in different applications for improving the sensitivity,selectivity,and speed of analysis of multi-compound in complex matrices. This flexible technique includes eight types of scan functions combined with selectable instrument parameters,which gives additional benefits when compared to traditional single full scan or SIM function. The sensitivity of PBDEs especially dece-BDE was improved by using multiple full scan and multiple simultaneous FS/SIM mode;the method development of multi-residue analysis of pesticides in food was simplified using a combination of FS and SIM展开更多
Chuanxiong Rhizoma(rhizomes of Ligusticumchuanxiong Hort)is a classical Chinese medicine,and it is usually used for the treatment of cardiovascular diseases.The essential oil is the main active constituent of Chuanxio...Chuanxiong Rhizoma(rhizomes of Ligusticumchuanxiong Hort)is a classical Chinese medicine,and it is usually used for the treatment of cardiovascular diseases.The essential oil is the main active constituent of Chuanxiong.In this study,a GC-MS quantitative method based on the SIM scanning mode and batch processing analysis was established,and the total contents of 3-butylidenephthalide and ligustilide were used as the indicators to optimize three extraction methods,including hydro-distillation extraction(HDE),ultrasound-assisted extraction(UAE)and supercritical fluid extraction(SFE).Then the volatile oil obtained by three extraction methods was analyzed qualitatively.The results showed that the volatile oil obtained by the UAE had the highest contents of 3-butylidenephthalide and ligustilide,the volatile oil extracted by HDE had the most types of chemical components,and the SFE volatile oil had the highest oil yield.展开更多
文摘Using quadrupole mass spectrometer,calibration gas PFTBA was turned on in constant flow to get the signal intensity,and off to get the noise value.Different scan time and dwell time was used separately for full scan mode and SIM to find out the effect of scan rate on signal intensity and noise.
文摘To find out the effect of scan rate on sensitivity in quadrupole mass spectrometer,DDV and 11 common hypnotic drugs were chosen for GC-MS analysis.Different scan time and dwell time was used separately for full scan mode and SIM.Then charasteristic ions were extracted to calculate signal to noise values.
文摘The comprehensive scan technique using single quadruple GC-MS was introduced and demonstrated in different applications for improving the sensitivity,selectivity,and speed of analysis of multi-compound in complex matrices. This flexible technique includes eight types of scan functions combined with selectable instrument parameters,which gives additional benefits when compared to traditional single full scan or SIM function. The sensitivity of PBDEs especially dece-BDE was improved by using multiple full scan and multiple simultaneous FS/SIM mode;the method development of multi-residue analysis of pesticides in food was simplified using a combination of FS and SIM
基金Shanxi pharmaceutical comprehensive development and utilization collaborative innovation center project(Grant No.2017JYXT15)Science and technology innovation team project of Shanxi University of Traditional Chinese Medicine(Grant No.2018TD-008)“Basic research project”of Shanxi University of traditional Chinese Medicine(Grant No.2020PY-JC-20)。
文摘Chuanxiong Rhizoma(rhizomes of Ligusticumchuanxiong Hort)is a classical Chinese medicine,and it is usually used for the treatment of cardiovascular diseases.The essential oil is the main active constituent of Chuanxiong.In this study,a GC-MS quantitative method based on the SIM scanning mode and batch processing analysis was established,and the total contents of 3-butylidenephthalide and ligustilide were used as the indicators to optimize three extraction methods,including hydro-distillation extraction(HDE),ultrasound-assisted extraction(UAE)and supercritical fluid extraction(SFE).Then the volatile oil obtained by three extraction methods was analyzed qualitatively.The results showed that the volatile oil obtained by the UAE had the highest contents of 3-butylidenephthalide and ligustilide,the volatile oil extracted by HDE had the most types of chemical components,and the SFE volatile oil had the highest oil yield.
