目的探索心房颤动(简称房颤)与氧化应激的关系。方法以住院行心脏换瓣手术的病人作为研究对象,按患者心律分为房颤组(n=22)和对照组(n=20),对照组为窦性心律。所有研究对象的心房肌组织样本,均作病理形态学观察,并用免疫组织化学法检测...目的探索心房颤动(简称房颤)与氧化应激的关系。方法以住院行心脏换瓣手术的病人作为研究对象,按患者心律分为房颤组(n=22)和对照组(n=20),对照组为窦性心律。所有研究对象的心房肌组织样本,均作病理形态学观察,并用免疫组织化学法检测其热休克蛋白60(HSP60)表达;用乳胶增强免疫比浊法测定其血清C-反应蛋白(CRP)水平。结果房颤病人的心肌细胞肥大与间质纤维化程度都比对照组明显。HSP60表达阳性率房颤组高于对照组(68.2%vs 25.0%),灰度值房颤组低于对照组(157.69±16.00 vs 178.69±28.63)。血清CRP含量房颤组高于对照组(20.72±17.92 mg/L vs 6.80±6.26 mg/L,P均<0.05)。结论氧化应激与房颤关系密切。展开更多
Polymerization of C60 is realized under high temperature and high pressure. X-ray diffraction reveals a rhombohedral lattice structure in the product, and solid-state ^13C nuclear magnetic resonance spectroscopy confi...Polymerization of C60 is realized under high temperature and high pressure. X-ray diffraction reveals a rhombohedral lattice structure in the product, and solid-state ^13C nuclear magnetic resonance spectroscopy confirms the formation of sp^3 bonds between C60 molecules. Specific heat is then measured over the temperature range of 300-2 K. It is found that its specific heat values are significantly less than those in fullerite within the region of 80-2K, and this huge reduction is attributed to the suppression of intermolecular librational modes in polymerized C60. An excellent fit to the experimental data over the entire temperature range is provided by a model, which needs to include only three-dimensional and two-dimensional translational modes in various contributions at different temperatures.展开更多
An initial investigation on the roughness and frictional properties of the self-assembled thin films from polyelectrolytes is presented. Star-shaped C-60-Poly(styrene-maleic anhydride) was successful prepared. The mul...An initial investigation on the roughness and frictional properties of the self-assembled thin films from polyelectrolytes is presented. Star-shaped C-60-Poly(styrene-maleic anhydride) was successful prepared. The multilayer thin films have been fabricated on mica with diazoresin as the cationic polyelectrolyte and hydrolyzed star-shaped C-60-poly(styrene-maleic anhydride) as the anionic polyelectrolyte via self-assembly technique. The crosslinking structure of the films is formed from the conversion of ionic bond to covalent bond after UV irradiation. AFM/FFM investigations provide insights into the roughness and frictional properties on a microscale. The roughness depends strongly on the number of film layers in the case of C-60-containing films. The frictional forces of the films exhibited a well behaved non-linear relationship in response to the change of applied load. It supports the prediction of enhanced load-bearing property Of C60-containing thin films.展开更多
The influence of pre-deformation and heat treatment on mechanicalproperties of as-extruded ZK60 alloy was investigated.The experimentalresults indicated that the solid solution,pre-cold rolling and artificialaging tre...The influence of pre-deformation and heat treatment on mechanicalproperties of as-extruded ZK60 alloy was investigated.The experimentalresults indicated that the solid solution,pre-cold rolling and artificialaging treatments remarkably improved the mechanicalstrength of alloys compared with the asextruded condition.Especially,pre-cold rolling in 5% reduction combined with artificialaging at 150 ℃ for 20 h was determined as the optimum heat treatment condition,which resulted in a yield strength of 333 MPa with an increment of 87 MPa and ultimate tensile strength of 373 MPa.High density of nanoscale precipitates in α-Mg matrix observed in this sample was beneficialto enhancing the strength.The as-extruded sample showed a typicalbrittle fracture while the solution treated sample exhibited ductile-fragile failure characterized by cleavage fractures,river patterns,and tear ridges.And the sample after pre-cold rolling combined with aging presented more equiaxialdimples with a great amount of cracked particles in them.The above-mentioned observations were analyzed in terms of microstructure and possible strengthening mechanism in the extruded ZK60 alloy.展开更多
A new approach to fullerene ferrocenyl derivative has been made. [60]Fullerene reacts with ferrocenylmethyl azide to give N-ferrocenylmethyl imino[60]fullerene in 42% yield.
文摘目的探索心房颤动(简称房颤)与氧化应激的关系。方法以住院行心脏换瓣手术的病人作为研究对象,按患者心律分为房颤组(n=22)和对照组(n=20),对照组为窦性心律。所有研究对象的心房肌组织样本,均作病理形态学观察,并用免疫组织化学法检测其热休克蛋白60(HSP60)表达;用乳胶增强免疫比浊法测定其血清C-反应蛋白(CRP)水平。结果房颤病人的心肌细胞肥大与间质纤维化程度都比对照组明显。HSP60表达阳性率房颤组高于对照组(68.2%vs 25.0%),灰度值房颤组低于对照组(157.69±16.00 vs 178.69±28.63)。血清CRP含量房颤组高于对照组(20.72±17.92 mg/L vs 6.80±6.26 mg/L,P均<0.05)。结论氧化应激与房颤关系密切。
基金Supported by the National Basic Research Programme of China under Grant No 2006CB705600, the National Natural Science Foundation of China under Grant No 10674060, the Natural Science Foundation of Jiangsu Province under Grant No BK2006109, the Doctoral Programme in Higher Education, and Baptist University of Hong Kong （FRG/05-06/I-52）.
文摘Polymerization of C60 is realized under high temperature and high pressure. X-ray diffraction reveals a rhombohedral lattice structure in the product, and solid-state ^13C nuclear magnetic resonance spectroscopy confirms the formation of sp^3 bonds between C60 molecules. Specific heat is then measured over the temperature range of 300-2 K. It is found that its specific heat values are significantly less than those in fullerite within the region of 80-2K, and this huge reduction is attributed to the suppression of intermolecular librational modes in polymerized C60. An excellent fit to the experimental data over the entire temperature range is provided by a model, which needs to include only three-dimensional and two-dimensional translational modes in various contributions at different temperatures.
基金This project is financially supported by the National Natural Science Foundation of China (No. 59843008).
文摘An initial investigation on the roughness and frictional properties of the self-assembled thin films from polyelectrolytes is presented. Star-shaped C-60-Poly(styrene-maleic anhydride) was successful prepared. The multilayer thin films have been fabricated on mica with diazoresin as the cationic polyelectrolyte and hydrolyzed star-shaped C-60-poly(styrene-maleic anhydride) as the anionic polyelectrolyte via self-assembly technique. The crosslinking structure of the films is formed from the conversion of ionic bond to covalent bond after UV irradiation. AFM/FFM investigations provide insights into the roughness and frictional properties on a microscale. The roughness depends strongly on the number of film layers in the case of C-60-containing films. The frictional forces of the films exhibited a well behaved non-linear relationship in response to the change of applied load. It supports the prediction of enhanced load-bearing property Of C60-containing thin films.
基金Funded by the National Natural Science Foundation of China(No.51571043)the International Science&Technology Cooperation Program of China(No.2014DFG52810)the Fundamental Research Funds for the Central Universities(No.106112015CDJZR135515)
文摘The influence of pre-deformation and heat treatment on mechanicalproperties of as-extruded ZK60 alloy was investigated.The experimentalresults indicated that the solid solution,pre-cold rolling and artificialaging treatments remarkably improved the mechanicalstrength of alloys compared with the asextruded condition.Especially,pre-cold rolling in 5% reduction combined with artificialaging at 150 ℃ for 20 h was determined as the optimum heat treatment condition,which resulted in a yield strength of 333 MPa with an increment of 87 MPa and ultimate tensile strength of 373 MPa.High density of nanoscale precipitates in α-Mg matrix observed in this sample was beneficialto enhancing the strength.The as-extruded sample showed a typicalbrittle fracture while the solution treated sample exhibited ductile-fragile failure characterized by cleavage fractures,river patterns,and tear ridges.And the sample after pre-cold rolling combined with aging presented more equiaxialdimples with a great amount of cracked particles in them.The above-mentioned observations were analyzed in terms of microstructure and possible strengthening mechanism in the extruded ZK60 alloy.
文摘A new approach to fullerene ferrocenyl derivative has been made. [60]Fullerene reacts with ferrocenylmethyl azide to give N-ferrocenylmethyl imino[60]fullerene in 42% yield.
