目的:对比分析18F-Na F PET/CT与99m Tc-MDP SPECT/CT诊断前列腺癌骨转移灶的临床价值。方法:回顾性分析32例前列腺癌患者(2013年9月至2015年3月)骨转移灶。32例患者均在我科接受了18F-Na F PET/CT与99m Tc-MDP SPECT/CT检查,两种检查...目的:对比分析18F-Na F PET/CT与99m Tc-MDP SPECT/CT诊断前列腺癌骨转移灶的临床价值。方法:回顾性分析32例前列腺癌患者(2013年9月至2015年3月)骨转移灶。32例患者均在我科接受了18F-Na F PET/CT与99m Tc-MDP SPECT/CT检查,两种检查最长间隔不超过一周,以病理学结果或随访结果对显像进行分析。结果:18F-Na F PET/CT骨扫描探测到32例患者中31人存在骨转移灶,其中20处骨骼病灶性质待定。99mTc-MDP SPECT/CT骨显像探测到32例患者中30人存在骨转移灶,18处骨骼病灶性质待定。18F-Na F PET/CT骨显像图像的质量及分辨率均优于99m Tc-MDP SPECT/CT骨显像。18F-Na F PET/CT骨显像和99m Tc-MDP SPECT/CT骨显像诊断前列腺癌骨转移灶的灵敏度分别为97.2%和61%;特异度分别为100%和100%;两种显像方法的阳性预测值分别为100%和100%,而阴性预测值为95.4%和59.7%。结论:18F-Na F PET/CT骨显像评价前列腺癌骨转移灶较99m Tc-MDP SPECT/CT骨显像灵敏度、阴性预测值高,在临床上有更好的应用价值。展开更多
The proposed phantom is designed for the quality control of micro-SPECT/CT and micro-PET/CT systems. However, it is an assembly of six patterns stored in a cylindrical box enabling to control both micro-SPECT unit in ...The proposed phantom is designed for the quality control of micro-SPECT/CT and micro-PET/CT systems. However, it is an assembly of six patterns stored in a cylindrical box enabling to control both micro-SPECT unit in terms of uniformity, spatial linearity and spatial resolution and micro-CT unit in terms of uniformity, spatial linearity, spatial resolution, diffusion rate, low contrast detectability, Hounsfield unit linearity and slice thickness. The construction material is Plexiglas. As for the implementation, it was made on a micro-SPECT/CT machine of the type “speCZT eXplore CT 120”. Compared to the NEMA NU 4-2008 image quality phantom, this phantom offers micro-CT quality control and is more efficient in control of spatial resolution for micro-SPECT and micro- PET systems.展开更多
文摘目的:对比分析18F-Na F PET/CT与99m Tc-MDP SPECT/CT诊断前列腺癌骨转移灶的临床价值。方法:回顾性分析32例前列腺癌患者(2013年9月至2015年3月)骨转移灶。32例患者均在我科接受了18F-Na F PET/CT与99m Tc-MDP SPECT/CT检查,两种检查最长间隔不超过一周,以病理学结果或随访结果对显像进行分析。结果:18F-Na F PET/CT骨扫描探测到32例患者中31人存在骨转移灶,其中20处骨骼病灶性质待定。99mTc-MDP SPECT/CT骨显像探测到32例患者中30人存在骨转移灶,18处骨骼病灶性质待定。18F-Na F PET/CT骨显像图像的质量及分辨率均优于99m Tc-MDP SPECT/CT骨显像。18F-Na F PET/CT骨显像和99m Tc-MDP SPECT/CT骨显像诊断前列腺癌骨转移灶的灵敏度分别为97.2%和61%;特异度分别为100%和100%;两种显像方法的阳性预测值分别为100%和100%,而阴性预测值为95.4%和59.7%。结论:18F-Na F PET/CT骨显像评价前列腺癌骨转移灶较99m Tc-MDP SPECT/CT骨显像灵敏度、阴性预测值高,在临床上有更好的应用价值。
文摘The proposed phantom is designed for the quality control of micro-SPECT/CT and micro-PET/CT systems. However, it is an assembly of six patterns stored in a cylindrical box enabling to control both micro-SPECT unit in terms of uniformity, spatial linearity and spatial resolution and micro-CT unit in terms of uniformity, spatial linearity, spatial resolution, diffusion rate, low contrast detectability, Hounsfield unit linearity and slice thickness. The construction material is Plexiglas. As for the implementation, it was made on a micro-SPECT/CT machine of the type “speCZT eXplore CT 120”. Compared to the NEMA NU 4-2008 image quality phantom, this phantom offers micro-CT quality control and is more efficient in control of spatial resolution for micro-SPECT and micro- PET systems.