目的:探讨妊娠期高血压疾病(hypertensive disorders of pregnancy,HDP)患者孕晚期胎盘剪切波速度(SWV)值、脐动脉收缩压与舒张压比值(脐动脉S/D值)预测围产儿预后的临床价值。方法:选取上海市东方医院吉安医院2020年1月-2022年1月收治...目的:探讨妊娠期高血压疾病(hypertensive disorders of pregnancy,HDP)患者孕晚期胎盘剪切波速度(SWV)值、脐动脉收缩压与舒张压比值(脐动脉S/D值)预测围产儿预后的临床价值。方法:选取上海市东方医院吉安医院2020年1月-2022年1月收治的HDP孕妇和血压正常孕妇203例为研究样本,HDP孕妇为观察组(n=102),血压正常孕妇为对照组(n=101),采用声辐射力脉冲成像超声诊断仪监测反映胎盘弹性的胎盘SWV值、围产儿脐动脉S/D值,比较两组胎盘SWV值、脐动脉S/D值,分析其预测围产儿预后的价值。结果:观察组围产儿不良结局发生率高于对照组(P<0.05);观察组妊娠正常结局孕妇胎盘SWV值、脐动脉S/D值与对照组相比,差异均无统计学意义(P>0.05),观察组妊娠不良结局孕妇胎盘SWV值、脐动脉S/D值均高于正常结局与对照组(P<0.05);受试者工作特征(ROC)曲线反映,胎盘SWV值预测妊娠不良结局约登(Youden)指数最大0.790时对应截断值(Cutoff)1.000 m/s,曲线下面积(AUC)0.892,预测HDP妊娠不良结局的敏感度86.84%,特异度90.62%;脐动脉S/D值预测妊娠不良结局Youden指数最大0.790时对应Cut-off为2.800,AUC为0.894,预测妊娠不良结局敏感度为86.84%,特异度为92.19%。结论:孕晚期反映胎盘弹性的胎盘SWV值、脐动脉S/D值在评价胎盘功能上有参考意义,为妊娠期高血压疾病孕妇的临床诊断提供了新维度的超声参考价值,为评估围产儿预后提供一定程度的科学证据。展开更多
Based on the 6-hour-interval reanalysis data with 1°× 1°resolution from the National Center for Environmental Prediction/the National Center for Atmospheric Research (NCEP/NCAR), the eddy kinetic ener...Based on the 6-hour-interval reanalysis data with 1°× 1°resolution from the National Center for Environmental Prediction/the National Center for Atmospheric Research (NCEP/NCAR), the eddy kinetic energy (EKE) budget of a southwest vortex (SWV) that caused heavy rainfall in Guangxi over South China (from 1200 UTC 11 to 0000 UTC 13 June) is calculated. The results are as follows: (a) The SWV is a kind of subtropical vortex, with characteristics of both an extratropical vortex and a tropical vortex. (b) In the case examined, large-scale circulation and other perturbation fields contributed to the formation and development of the SWV. (c) When the SWV moved from weak large-scale circulation EKE areas to strong ones, the EKE of the SWV increased, and vice versa. (d) Sub-grid processes and frictional dissipation were the main sinks of the SWV EKE, which contributed to the decay of the SWV. (e) The residual term (RES) and the Total (composite effect of all right hand side (rhs) terms except the RES in the EKE equation) varied almost in the same tendency, which kept the EKE varying in a moderate way. (f) The EKE between 550 hPa and 850 hPa increased most intensively, corresponding to the vertical stretching of the SWV.展开更多
文摘目的:探讨妊娠期高血压疾病(hypertensive disorders of pregnancy,HDP)患者孕晚期胎盘剪切波速度(SWV)值、脐动脉收缩压与舒张压比值(脐动脉S/D值)预测围产儿预后的临床价值。方法:选取上海市东方医院吉安医院2020年1月-2022年1月收治的HDP孕妇和血压正常孕妇203例为研究样本,HDP孕妇为观察组(n=102),血压正常孕妇为对照组(n=101),采用声辐射力脉冲成像超声诊断仪监测反映胎盘弹性的胎盘SWV值、围产儿脐动脉S/D值,比较两组胎盘SWV值、脐动脉S/D值,分析其预测围产儿预后的价值。结果:观察组围产儿不良结局发生率高于对照组(P<0.05);观察组妊娠正常结局孕妇胎盘SWV值、脐动脉S/D值与对照组相比,差异均无统计学意义(P>0.05),观察组妊娠不良结局孕妇胎盘SWV值、脐动脉S/D值均高于正常结局与对照组(P<0.05);受试者工作特征(ROC)曲线反映,胎盘SWV值预测妊娠不良结局约登(Youden)指数最大0.790时对应截断值(Cutoff)1.000 m/s,曲线下面积(AUC)0.892,预测HDP妊娠不良结局的敏感度86.84%,特异度90.62%;脐动脉S/D值预测妊娠不良结局Youden指数最大0.790时对应Cut-off为2.800,AUC为0.894,预测妊娠不良结局敏感度为86.84%,特异度为92.19%。结论:孕晚期反映胎盘弹性的胎盘SWV值、脐动脉S/D值在评价胎盘功能上有参考意义,为妊娠期高血压疾病孕妇的临床诊断提供了新维度的超声参考价值,为评估围产儿预后提供一定程度的科学证据。
基金supported by the National Natural Science Foundation of China under Grant Nos. 40875021 and 40605016the foundation of the Institute of Heavy Rain, Wuhan under Grant No. IHR2007K05
文摘Based on the 6-hour-interval reanalysis data with 1°× 1°resolution from the National Center for Environmental Prediction/the National Center for Atmospheric Research (NCEP/NCAR), the eddy kinetic energy (EKE) budget of a southwest vortex (SWV) that caused heavy rainfall in Guangxi over South China (from 1200 UTC 11 to 0000 UTC 13 June) is calculated. The results are as follows: (a) The SWV is a kind of subtropical vortex, with characteristics of both an extratropical vortex and a tropical vortex. (b) In the case examined, large-scale circulation and other perturbation fields contributed to the formation and development of the SWV. (c) When the SWV moved from weak large-scale circulation EKE areas to strong ones, the EKE of the SWV increased, and vice versa. (d) Sub-grid processes and frictional dissipation were the main sinks of the SWV EKE, which contributed to the decay of the SWV. (e) The residual term (RES) and the Total (composite effect of all right hand side (rhs) terms except the RES in the EKE equation) varied almost in the same tendency, which kept the EKE varying in a moderate way. (f) The EKE between 550 hPa and 850 hPa increased most intensively, corresponding to the vertical stretching of the SWV.