This paper describes the development of a knowledgebased system (KBS) for determining whether or not, and under what conditions, a bank Ioan officer should grant a business loan to a company. The prototype system deve...This paper describes the development of a knowledgebased system (KBS) for determining whether or not, and under what conditions, a bank Ioan officer should grant a business loan to a company. The prototype system developed focuses on what is bank loans risks management, how to prevent risk by the analysis of the ability of paying back loans. The paper makes the structural analysis involved in the system's decision situation, the structured situation diagram or model, dependency diagram and the document needed by the KBS prototype system thus are developed. Through testing the samples from loan business, the quality for the analysis of the ability of paying back loans can be effectively evaluated by the KBS prototype system.展开更多
To describe the current aging population in China and globally,especially as it applies to age-related macular degeneration(AMD).To review the current standards of care for treating both wet(exudative)eAMD and dry(atr...To describe the current aging population in China and globally,especially as it applies to age-related macular degeneration(AMD).To review the current standards of care for treating both wet(exudative)eAMD and dry(atrophic)aAMD.And to introduce a model for experimentation that is based on the Age-Related Eye Disease Study(AREDS)using eye bank tissue.A literature search that outlines current aging populations,standards of clinical treatment as defined by large,multicenter,randomized clinical trials that present level-I data with a low risk for bias.An experimental model system of AMD is presented that enables scientific analysis of AMD pathogenesis by applying grading criteria from the AREDS to human eye bank eyes.Analysis includes proteomic,cellular,and functional genomics.The standard of care for the treatment of eAMD is currently defined by the use of several anti-vascular endothelial growth(anti-VEGF)agents alone or in combination with photodynamic therapy.Monotherapy treatment intervals may be monthly,as needed,or by using a treat-and-extend(TAE)protocol.There are no proven therapies for aAMD.AMD that is phenotypically defined at AREDS level 3,should be managed with the use of anti-oxidant vitamins,lutein/zeaxanthin and zinc(AREDS-2 formulation).By understanding the multiple etiologies in the pathogenesis of AMD(i.e.,oxidative stress,inflammation,and genetics),the use of human eye bank tissues graded according to the Minnesota Grading System(MGS)will enable future insights into the pathogenesis of AMD.Initial AMD management is with lifestyle modification such as avoiding smoking,eating a healthy diet and using appropriate vitamin supplements(AREDS-2).For eAMD,anti-VEGF therapies using either pro re nata(PRN)or TAE protocols are recommended,with photodynamic therapy in appropriate cases.New cellular information will direct future,potential therapies and these will originate from experimental models,such as the proposed eye bank model using the MGS,that leverages the prospective AREDS database.展开更多
In this practicum, the program objective is to improve the health of Joseph’s Storehouse food bank recipients’ community in the Blessing Center (New Hope Free Clinic and Joseph’s food bank), Redlands, California. T...In this practicum, the program objective is to improve the health of Joseph’s Storehouse food bank recipients’ community in the Blessing Center (New Hope Free Clinic and Joseph’s food bank), Redlands, California. The approach is to implement primary prevention and secondary prevention activity to increase knowledge and skills of the clients and their families of how to prevent and control type 2 diabetes through a wellness program in the clinic. The practicum began January 2015 and ended April 2015. 53 food bank recipients (non-diabetic and diabetic) were recruited. A quasi-experimental study design, pre-test/posttest, was used for the study. The impact of the program targeted diverse audience, high risk ethnic groups, and improved knowledge, awareness, management, and positive behavioral change. The study implication for public health promotion specialists is to narrow venues targeting the most vulnerable populations to promote and reduce type 2 diabetes.展开更多
A framework of IIR two-channel bi-orthogonal filter banks is presented. The design of the analysis/synthesis systems reduces to the design of a single transfer function. The wavelet bases corresponding to the IIR m...A framework of IIR two-channel bi-orthogonal filter banks is presented. The design of the analysis/synthesis systems reduces to the design of a single transfer function. The wavelet bases corresponding to the IIR maximally flat filters are generated. Use the wavelet bases in wavelet packets analysis, take information entropy function as information cost function, adjust the best bases dynamically, and the section of signal's spectramfits its characteristics well. A lot of audio signals are processed. Compared to that of the wavelet transform and the wavelet packet transform using the Daubechies' wavelet which has the same order with our IIR wavelet, the properties of our system are better展开更多
目的:系统评价我国居民对时间银行养老模式参与意愿。方法:2022年1月31日,计算机检索中国知网、万方数据库、中国生物医学文献数据库、维普数据库、PubMed、Web of Science、Wiley数据库中有关我国居民对时间银行养老模式参与意愿的横...目的:系统评价我国居民对时间银行养老模式参与意愿。方法:2022年1月31日,计算机检索中国知网、万方数据库、中国生物医学文献数据库、维普数据库、PubMed、Web of Science、Wiley数据库中有关我国居民对时间银行养老模式参与意愿的横断面研究。由2名研究者根据纳入和排除标准独立筛选文献、提取数据,并根据美国卫生保健质量和研究机构(AHRQ)推荐的横断面研究质量评价标准评价纳入文献偏倚后,采用R软件4.1.2软件进行Meta分析。结果:共纳入31项横断面研究,涉及16500名有效研究对象,愿意参与时间银行养老模式的居民9442人。采用AHRQ进行文献质量评价,28项研究质量为中等以上。我国居民时间银行养老模式的参与意愿率为64.65%[95%CI(59.01%,69.90%)]。亚组分析显示,个体层面中,女性(50.2%)参与意愿高于男性(46.3%),55~<60岁的居民愿意参与率80.9%,高于60~<70岁(73.8%)、70~<80岁(76.6%)、≥80岁(37.5%)年龄段居民(P<0.001);中共党员愿意参与率(82.9%)高于非中共党员(69.1%)(P<0.001);专科及以上学历水平者参与意愿最高(62.0%),但参与意愿与学历水平未呈现完全线性相关(P=0.004);经济宽裕(42.0%)或者贫困(44.0%)的居民参与率高于经济水平一般者(18.7%)(P<0.001);身体健康者参与意愿(79.2%)高于一般(68.4%)或较差(42.5%)者(P<0.001)。家庭层面中,有配偶者参与意愿(48.7%)高于无配偶者(38.0%)(P<0.001);子女数量为1个或2个者参与意愿(79.4%)高于多个者(71.3%)(P<0.001);只与配偶同住者参与意愿较高(51.1%),高于与配偶子女同住者(47.1%)、独居者(45.8%)和只与子女同住者(45.1%)(P<0.001)。社会层面中,东北部(69.3%)和中部(61.0%)居住居民参与意愿高于东部(53.5%)及西部(49.9%)居民(P<0.001);了解时间银行项目者(62.1%)相较不了解者(35.1%)更愿意参与(P<0.001)。结论:现有证据表明,我国居民对时间银行养老模式参与意愿处于中等稍高水平。女性、55~>60岁、中共党员、学历层次专科及以上、经济宽裕/贫困、健康水平较高、有配偶、子女数量较少(1个或2个)、只与配偶同住、东北部/中部地区、了解时间银行的居民参与时间银行养老模式的意愿相对更强。以上结论需要未来更多高质量的研究进行验证。展开更多
基金Supported by the National Science Foundation of China(No.7977086)
文摘This paper describes the development of a knowledgebased system (KBS) for determining whether or not, and under what conditions, a bank Ioan officer should grant a business loan to a company. The prototype system developed focuses on what is bank loans risks management, how to prevent risk by the analysis of the ability of paying back loans. The paper makes the structural analysis involved in the system's decision situation, the structured situation diagram or model, dependency diagram and the document needed by the KBS prototype system thus are developed. Through testing the samples from loan business, the quality for the analysis of the ability of paying back loans can be effectively evaluated by the KBS prototype system.
基金This work was supported in part by NIH/NIA RO1 AG025392 NIH/NEI:RO1 EY022097,JoAnne Smith and Delta Airlines Charitable Donation,and an unrestricted grant from Research to Prevent Blindness to the Mayo Clinic,Department of Ophthalmology,Rochester,MN,USA.
文摘To describe the current aging population in China and globally,especially as it applies to age-related macular degeneration(AMD).To review the current standards of care for treating both wet(exudative)eAMD and dry(atrophic)aAMD.And to introduce a model for experimentation that is based on the Age-Related Eye Disease Study(AREDS)using eye bank tissue.A literature search that outlines current aging populations,standards of clinical treatment as defined by large,multicenter,randomized clinical trials that present level-I data with a low risk for bias.An experimental model system of AMD is presented that enables scientific analysis of AMD pathogenesis by applying grading criteria from the AREDS to human eye bank eyes.Analysis includes proteomic,cellular,and functional genomics.The standard of care for the treatment of eAMD is currently defined by the use of several anti-vascular endothelial growth(anti-VEGF)agents alone or in combination with photodynamic therapy.Monotherapy treatment intervals may be monthly,as needed,or by using a treat-and-extend(TAE)protocol.There are no proven therapies for aAMD.AMD that is phenotypically defined at AREDS level 3,should be managed with the use of anti-oxidant vitamins,lutein/zeaxanthin and zinc(AREDS-2 formulation).By understanding the multiple etiologies in the pathogenesis of AMD(i.e.,oxidative stress,inflammation,and genetics),the use of human eye bank tissues graded according to the Minnesota Grading System(MGS)will enable future insights into the pathogenesis of AMD.Initial AMD management is with lifestyle modification such as avoiding smoking,eating a healthy diet and using appropriate vitamin supplements(AREDS-2).For eAMD,anti-VEGF therapies using either pro re nata(PRN)or TAE protocols are recommended,with photodynamic therapy in appropriate cases.New cellular information will direct future,potential therapies and these will originate from experimental models,such as the proposed eye bank model using the MGS,that leverages the prospective AREDS database.
文摘In this practicum, the program objective is to improve the health of Joseph’s Storehouse food bank recipients’ community in the Blessing Center (New Hope Free Clinic and Joseph’s food bank), Redlands, California. The approach is to implement primary prevention and secondary prevention activity to increase knowledge and skills of the clients and their families of how to prevent and control type 2 diabetes through a wellness program in the clinic. The practicum began January 2015 and ended April 2015. 53 food bank recipients (non-diabetic and diabetic) were recruited. A quasi-experimental study design, pre-test/posttest, was used for the study. The impact of the program targeted diverse audience, high risk ethnic groups, and improved knowledge, awareness, management, and positive behavioral change. The study implication for public health promotion specialists is to narrow venues targeting the most vulnerable populations to promote and reduce type 2 diabetes.
文摘A framework of IIR two-channel bi-orthogonal filter banks is presented. The design of the analysis/synthesis systems reduces to the design of a single transfer function. The wavelet bases corresponding to the IIR maximally flat filters are generated. Use the wavelet bases in wavelet packets analysis, take information entropy function as information cost function, adjust the best bases dynamically, and the section of signal's spectramfits its characteristics well. A lot of audio signals are processed. Compared to that of the wavelet transform and the wavelet packet transform using the Daubechies' wavelet which has the same order with our IIR wavelet, the properties of our system are better
文摘目的:系统评价我国居民对时间银行养老模式参与意愿。方法:2022年1月31日,计算机检索中国知网、万方数据库、中国生物医学文献数据库、维普数据库、PubMed、Web of Science、Wiley数据库中有关我国居民对时间银行养老模式参与意愿的横断面研究。由2名研究者根据纳入和排除标准独立筛选文献、提取数据,并根据美国卫生保健质量和研究机构(AHRQ)推荐的横断面研究质量评价标准评价纳入文献偏倚后,采用R软件4.1.2软件进行Meta分析。结果:共纳入31项横断面研究,涉及16500名有效研究对象,愿意参与时间银行养老模式的居民9442人。采用AHRQ进行文献质量评价,28项研究质量为中等以上。我国居民时间银行养老模式的参与意愿率为64.65%[95%CI(59.01%,69.90%)]。亚组分析显示,个体层面中,女性(50.2%)参与意愿高于男性(46.3%),55~<60岁的居民愿意参与率80.9%,高于60~<70岁(73.8%)、70~<80岁(76.6%)、≥80岁(37.5%)年龄段居民(P<0.001);中共党员愿意参与率(82.9%)高于非中共党员(69.1%)(P<0.001);专科及以上学历水平者参与意愿最高(62.0%),但参与意愿与学历水平未呈现完全线性相关(P=0.004);经济宽裕(42.0%)或者贫困(44.0%)的居民参与率高于经济水平一般者(18.7%)(P<0.001);身体健康者参与意愿(79.2%)高于一般(68.4%)或较差(42.5%)者(P<0.001)。家庭层面中,有配偶者参与意愿(48.7%)高于无配偶者(38.0%)(P<0.001);子女数量为1个或2个者参与意愿(79.4%)高于多个者(71.3%)(P<0.001);只与配偶同住者参与意愿较高(51.1%),高于与配偶子女同住者(47.1%)、独居者(45.8%)和只与子女同住者(45.1%)(P<0.001)。社会层面中,东北部(69.3%)和中部(61.0%)居住居民参与意愿高于东部(53.5%)及西部(49.9%)居民(P<0.001);了解时间银行项目者(62.1%)相较不了解者(35.1%)更愿意参与(P<0.001)。结论:现有证据表明,我国居民对时间银行养老模式参与意愿处于中等稍高水平。女性、55~>60岁、中共党员、学历层次专科及以上、经济宽裕/贫困、健康水平较高、有配偶、子女数量较少(1个或2个)、只与配偶同住、东北部/中部地区、了解时间银行的居民参与时间银行养老模式的意愿相对更强。以上结论需要未来更多高质量的研究进行验证。
