Selective benzoylation of secondary hydroxyl on sugar moiety of various ribosides including N-ribosides, O-rihosides and 2＇-deoxy-N-riboside was investigated by using benzoyl chloride and Na2CO3 in aqueous CH3CN. The...Selective benzoylation of secondary hydroxyl on sugar moiety of various ribosides including N-ribosides, O-rihosides and 2＇-deoxy-N-riboside was investigated by using benzoyl chloride and Na2CO3 in aqueous CH3CN. The influence of the aglycone and sugar moiety on the selectivity of benzoylation was discussed as well. A most ef- ficient method for preparation of 2＇,3＇-O-dibenzoylnucleosides was developed.展开更多
文摘Selective benzoylation of secondary hydroxyl on sugar moiety of various ribosides including N-ribosides, O-rihosides and 2＇-deoxy-N-riboside was investigated by using benzoyl chloride and Na2CO3 in aqueous CH3CN. The influence of the aglycone and sugar moiety on the selectivity of benzoylation was discussed as well. A most ef- ficient method for preparation of 2＇,3＇-O-dibenzoylnucleosides was developed.
